메뉴 건너뛰기




Volumn 122, Issue 12, 2009, Pages 2108-2118

EFA6A encodes two isoforms with distinct biological activities in neuronal cells

Author keywords

ARF6 GEF; Cytoskeletal remodeling; Dendrite branching; EFA6A; Neurite extension; Neurons; Rho GTPases

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 6; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MESSENGER RNA; PROLINE; PROTEIN EFA6A; UNCLASSIFIED DRUG; ISOPROTEIN; PSD PROTEIN, RAT;

EID: 68949170695     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.042325     Document Type: Article
Times cited : (14)

References (43)
  • 1
    • 0037738555 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 and a functional PIX/p95-APP1 complex are required for Rac1B-mediated neurite outgrowth
    • Albertinazzi, C., Za, L., Paris, S. and de Curtis, I. (2003). ADP-ribosylation factor 6 and a functional PIX/p95-APP1 complex are required for Rac1B-mediated neurite outgrowth. Mol. Biol. Cell 14, 1295-1307.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 1295-1307
    • Albertinazzi, C.1    Za, L.2    Paris, S.3    de Curtis, I.4
  • 3
    • 0031889838 scopus 로고    scopus 로고
    • Regulated exocytosis in chromaffin cells: Translocation of ARF6 stimulates a plasma membrane-associated phospholipase D
    • Caumont, A. S., Galas, M. C., Vitale, N., Aunis, D. and Bader, M. F. (1998). Regulated exocytosis in chromaffin cells: translocation of ARF6 stimulates a plasma membrane-associated phospholipase D. J. Biol. Chem. 273, 1373-1379.
    • (1998) J. Biol. Chem , vol.273 , pp. 1373-1379
    • Caumont, A.S.1    Galas, M.C.2    Vitale, N.3    Aunis, D.4    Bader, M.F.5
  • 4
    • 33646934083 scopus 로고    scopus 로고
    • ARF6 and EFA6A regulate the development and maintenance of dendritic spines
    • Choi, S., Ko, J., Lee, J. R., Lee, H. W., Kim, K., Chung, H. S., Kim, H. and Kim, E. (2006). ARF6 and EFA6A regulate the development and maintenance of dendritic spines. J. Neurosci. 26, 4811-4819.
    • (2006) J. Neurosci , vol.26 , pp. 4811-4819
    • Choi, S.1    Ko, J.2    Lee, J.R.3    Lee, H.W.4    Kim, K.5    Chung, H.S.6    Kim, H.7    Kim, E.8
  • 5
    • 1642464740 scopus 로고    scopus 로고
    • Phylogenetic analysis of Sec7-domain-containing Arf nucleotide exchangers
    • Cox, R., Mason-Gamer, R. J., Jackson, C. L. and Segev, N. (2004). Phylogenetic analysis of Sec7-domain-containing Arf nucleotide exchangers. Mol. Biol. Cell 15, 1487-1505.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1487-1505
    • Cox, R.1    Mason-Gamer, R.J.2    Jackson, C.L.3    Segev, N.4
  • 6
    • 0036719449 scopus 로고    scopus 로고
    • Breaking the neuronal sphere: Regulation of the actin cytoskeleton in neuritogenesis
    • da Silva, J. S. and Dotti, C. G. (2002). Breaking the neuronal sphere: regulation of the actin cytoskeleton in neuritogenesis. Nat. Rev. Neurosci. 3, 694-704.
    • (2002) Nat. Rev. Neurosci , vol.3 , pp. 694-704
    • da Silva, J.S.1    Dotti, C.G.2
  • 7
    • 12144252914 scopus 로고    scopus 로고
    • + channel with EFA6, a GDP/GTP exchange factor for ARF6. EMBO Rep. 5, 1171-1175.
    • + channel with EFA6, a GDP/GTP exchange factor for ARF6. EMBO Rep. 5, 1171-1175.
  • 8
    • 0037099033 scopus 로고    scopus 로고
    • A conserved C-terminal domain of EFA6-family ARF6-guanine nucleotide exchange factors induces lengthening of microvilli-like membrane protrusions
    • Derrien, V., Couillault, C., Franco, M., Martineau, S., Montcourrier, P., Houlgatte, R. and Chavrier, P. (2002). A conserved C-terminal domain of EFA6-family ARF6-guanine nucleotide exchange factors induces lengthening of microvilli-like membrane protrusions. J. Cell Sci. 115, 2867-2879.
    • (2002) J. Cell Sci , vol.115 , pp. 2867-2879
    • Derrien, V.1    Couillault, C.2    Franco, M.3    Martineau, S.4    Montcourrier, P.5    Houlgatte, R.6    Chavrier, P.7
  • 9
    • 0142211351 scopus 로고    scopus 로고
    • Multiple roles for Arf6: Sorting, structuring, and signaling at the plasma membrane
    • Donaldson, J. G. (2003). Multiple roles for Arf6: sorting, structuring, and signaling at the plasma membrane. J. Biol. Chem. 278, 41573-41576.
    • (2003) J. Biol. Chem , vol.278 , pp. 41573-41576
    • Donaldson, J.G.1
  • 10
    • 33646184680 scopus 로고    scopus 로고
    • ARF proteins: Roles in membrane traffic and beyond
    • D'Souza-Schorey, C. and Chavrier, P. (2006). ARF proteins: roles in membrane traffic and beyond. Nat. Rev. Mol. Cell. Biol. 7, 347-358.
    • (2006) Nat. Rev. Mol. Cell. Biol , vol.7 , pp. 347-358
    • D'Souza-Schorey, C.1    Chavrier, P.2
  • 12
    • 0033560032 scopus 로고    scopus 로고
    • EFA6, a sec7 domain-containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization
    • Franco, M., Peters, P. J., Boretto, J., van Donselaar, E., Neri, A., D'Souza-Schorey, C. and Chavrier, P. (1999). EFA6, a sec7 domain-containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization. EMBO J. 18, 1480-1491.
    • (1999) EMBO J , vol.18 , pp. 1480-1491
    • Franco, M.1    Peters, P.J.2    Boretto, J.3    van Donselaar, E.4    Neri, A.5    D'Souza-Schorey, C.6    Chavrier, P.7
  • 13
    • 11844304062 scopus 로고    scopus 로고
    • The role of the Rho GTPases in neuronal development
    • Govek, E. E., Newey, S. E. and Van Aelst, L. (2005). The role of the Rho GTPases in neuronal development. Genes Dev. 19, 1-49.
    • (2005) Genes Dev , vol.19 , pp. 1-49
    • Govek, E.E.1    Newey, S.E.2    Van Aelst, L.3
  • 15
    • 0036300155 scopus 로고    scopus 로고
    • Regulation of dendritic development by the ARF exchange factor ARNO
    • Hernandez-Deviez, D. J., Casanova, J. E. and Wilson, J. M. (2002). Regulation of dendritic development by the ARF exchange factor ARNO. Nat. Neurosci. 5, 623-624.
    • (2002) Nat. Neurosci , vol.5 , pp. 623-624
    • Hernandez-Deviez, D.J.1    Casanova, J.E.2    Wilson, J.M.3
  • 16
    • 0346729933 scopus 로고    scopus 로고
    • ARNO and ARF6 regulate axonal elongation and branching through downstream activation of phosphatidylinositol 4-phosphate 5-kinase alpha
    • Hernandez-Deviez, D. J., Roth, M. G., Casanova, J. E. and Wilson, J. M. (2004). ARNO and ARF6 regulate axonal elongation and branching through downstream activation of phosphatidylinositol 4-phosphate 5-kinase alpha. Mol. Biol. Cell 15, 111-120.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 111-120
    • Hernandez-Deviez, D.J.1    Roth, M.G.2    Casanova, J.E.3    Wilson, J.M.4
  • 17
    • 0141918787 scopus 로고    scopus 로고
    • The control of dendrite development
    • Jan, Y. N. and Jan, L. Y. (2003). The control of dendrite development. Neuron 40, 229-242.
    • (2003) Neuron , vol.40 , pp. 229-242
    • Jan, Y.N.1    Jan, L.Y.2
  • 18
    • 34547812229 scopus 로고    scopus 로고
    • ARF6 in the nervous system
    • Jaworski, J. (2007). ARF6 in the nervous system. Eur. J. Cell Biol. 86, 513-524.
    • (2007) Eur. J. Cell Biol , vol.86 , pp. 513-524
    • Jaworski, J.1
  • 19
    • 0032555353 scopus 로고    scopus 로고
    • Complex regulation of multiple cytohesin-like genes in murine tissues and cells
    • Kim, H. S., Chen, Y. and Lonai, P. (1998). Complex regulation of multiple cytohesin-like genes in murine tissues and cells. FEBS Lett. 433, 312-326.
    • (1998) FEBS Lett , vol.433 , pp. 312-326
    • Kim, H.S.1    Chen, Y.2    Lonai, P.3
  • 20
    • 33744966028 scopus 로고    scopus 로고
    • Role of the Arf6 GDP/GTP cycle and Arf6 GTPase-activating proteins in actin remodeling and intracellular transport
    • Klein, S., Franco, M., Chardin, P. and Luton, F. (2006). Role of the Arf6 GDP/GTP cycle and Arf6 GTPase-activating proteins in actin remodeling and intracellular transport. J. Biol. Chem. 281, 12352-12361.
    • (2006) J. Biol. Chem , vol.281 , pp. 12352-12361
    • Klein, S.1    Franco, M.2    Chardin, P.3    Luton, F.4
  • 21
    • 0023665902 scopus 로고
    • An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs
    • Kozak, M. (1987). An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15, 8125-8148.
    • (1987) Nucleic Acids Res , vol.15 , pp. 8125-8148
    • Kozak, M.1
  • 22
    • 0030004228 scopus 로고    scopus 로고
    • Prediction and analysis of coiled-coil structures
    • Lupas, A. (1996). Prediction and analysis of coiled-coil structures. Methods Enzymol. 266, 513-525.
    • (1996) Methods Enzymol , vol.266 , pp. 513-525
    • Lupas, A.1
  • 23
    • 18144398598 scopus 로고    scopus 로고
    • Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells
    • Matsuya, S., Sakagami, H., Tohgo, A., Owada, Y., Shin, H. W., Takeshima, H., Nakayama, K., Kokubun, S. and Kondo, H. (2005). Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells. J. Neurochem. 93, 674-685.
    • (2005) J. Neurochem , vol.93 , pp. 674-685
    • Matsuya, S.1    Sakagami, H.2    Tohgo, A.3    Owada, Y.4    Shin, H.W.5    Takeshima, H.6    Nakayama, K.7    Kokubun, S.8    Kondo, H.9
  • 24
    • 28844440455 scopus 로고    scopus 로고
    • The small GTPase ADP-ribosylation factor 6 negatively regulates dendritic spine formation
    • Miyazaki, H., Yamazaki, M., Watanabe, H., Maehama, T., Yokozeki, T. and Kanaho, Y. (2005). The small GTPase ADP-ribosylation factor 6 negatively regulates dendritic spine formation. FEBS Lett. 579, 6834-6838.
    • (2005) FEBS Lett , vol.579 , pp. 6834-6838
    • Miyazaki, H.1    Yamazaki, M.2    Watanabe, H.3    Maehama, T.4    Yokozeki, T.5    Kanaho, Y.6
  • 25
    • 0037328748 scopus 로고    scopus 로고
    • Convergence of non-clathrin-and clathrin-derived endosomes involves Arf6 inactivation and changes in phosphoinositides
    • Naslavsky, N., Weigert, R. and Donaldson, J. G. (2003). Convergence of non-clathrin-and clathrin-derived endosomes involves Arf6 inactivation and changes in phosphoinositides. Mol. Biol. Cell 14, 417-431.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 417-431
    • Naslavsky, N.1    Weigert, R.2    Donaldson, J.G.3
  • 26
    • 0037477712 scopus 로고    scopus 로고
    • ADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages
    • Niedergang, F., Colucci-Guyon, E., Dubois, T., Raposo, G. and Chavrier, P. (2003). ADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages. J. Cell Biol. 161, 1143-1150.
    • (2003) J. Cell Biol , vol.161 , pp. 1143-1150
    • Niedergang, F.1    Colucci-Guyon, E.2    Dubois, T.3    Raposo, G.4    Chavrier, P.5
  • 27
    • 0010394995 scopus 로고    scopus 로고
    • Identification of a novel gene, PSD, adjacent to NFKB2/lyt-10, which contains Sec7 and pleckstrin-homology domains
    • Perletti, L., Talarico, D., Trecca, D., Ronchetti, D., Fracchiolla, N. S., Maiolo, A. T. and Neri, A. (1997). Identification of a novel gene, PSD, adjacent to NFKB2/lyt-10, which contains Sec7 and pleckstrin-homology domains. Genomics 46, 251-259.
    • (1997) Genomics , vol.46 , pp. 251-259
    • Perletti, L.1    Talarico, D.2    Trecca, D.3    Ronchetti, D.4    Fracchiolla, N.S.5    Maiolo, A.T.6    Neri, A.7
  • 28
    • 0346725004 scopus 로고    scopus 로고
    • Arf GAPs: Multifunctional proteins that regulate membrane traffic and actin remodelling
    • Randazzo, P. A. and Hirsch, D. S. (2004). Arf GAPs: multifunctional proteins that regulate membrane traffic and actin remodelling. Cell. Signal. 16, 401-413.
    • (2004) Cell. Signal , vol.16 , pp. 401-413
    • Randazzo, P.A.1    Hirsch, D.S.2
  • 30
    • 41949093164 scopus 로고    scopus 로고
    • The EFA6 family: Guanine nucleotide exchange factors for ADP ribosylation factor 6 at neuronal synapses
    • Sakagami, H. (2008). The EFA6 family: guanine nucleotide exchange factors for ADP ribosylation factor 6 at neuronal synapses. Tohoku J. Exp. Med. 214, 191-198.
    • (2008) Tohoku J. Exp. Med , vol.214 , pp. 191-198
    • Sakagami, H.1
  • 31
    • 1542359625 scopus 로고    scopus 로고
    • Somatodendritic localization of the mRNA for EFA6A, a guanine nucleotide exchange protein for ARF6, in rat hippocampus and its involvement in dendritic formation
    • Sakagami, H., Matsuya, S., Nishimura, H., Suzuki, R. and Kondo, H. (2004). Somatodendritic localization of the mRNA for EFA6A, a guanine nucleotide exchange protein for ARF6, in rat hippocampus and its involvement in dendritic formation. Eur. J. Neurosci. 19, 863-870.
    • (2004) Eur. J. Neurosci , vol.19 , pp. 863-870
    • Sakagami, H.1    Matsuya, S.2    Nishimura, H.3    Suzuki, R.4    Kondo, H.5
  • 32
    • 33745363517 scopus 로고    scopus 로고
    • Distinct spatiotemporal expression of EFA6D, a guanine nucleotide exchange factor for ARF6, among the EFA6 family in mouse brain
    • Sakagami, H., Suzuki, H., Kamata, A., Owada, Y., Fukunaga, K., Mayanagi, H. and Kondo, H. (2006). Distinct spatiotemporal expression of EFA6D, a guanine nucleotide exchange factor for ARF6, among the EFA6 family in mouse brain. Brain Res. 1093, 1-11.
    • (2006) Brain Res , vol.1093 , pp. 1-11
    • Sakagami, H.1    Suzuki, H.2    Kamata, A.3    Owada, Y.4    Fukunaga, K.5    Mayanagi, H.6    Kondo, H.7
  • 33
    • 33847046379 scopus 로고    scopus 로고
    • Somatodendritic localization of EFA6A, a guanine nucleotide exchange factor for ADP-ribosylation factor 6, and its possible interaction with alpha-actinin in dendritic spines
    • Sakagami, H., Honma, T., Sukegawa, J., Owada, Y., Yanagisawa, T. and Kondo, H. (2007). Somatodendritic localization of EFA6A, a guanine nucleotide exchange factor for ADP-ribosylation factor 6, and its possible interaction with alpha-actinin in dendritic spines. Eur. J. Neurosci. 25, 618-628.
    • (2007) Eur. J. Neurosci , vol.25 , pp. 618-628
    • Sakagami, H.1    Honma, T.2    Sukegawa, J.3    Owada, Y.4    Yanagisawa, T.5    Kondo, H.6
  • 34
    • 0035817625 scopus 로고    scopus 로고
    • Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D
    • Santy, L. C. and Casanova, J. E. (2001). Activation of ARF6 by ARNO stimulates epithelial cell migration through downstream activation of both Rac1 and phospholipase D. J. Cell Biol. 154, 599-610.
    • (2001) J. Cell Biol , vol.154 , pp. 599-610
    • Santy, L.C.1    Casanova, J.E.2
  • 35
    • 0037178797 scopus 로고    scopus 로고
    • Localization and activation of the ARF6 GTPase during cleavage furrow ingression and cytokinesis
    • Schweitzer, J. K. and D'Souza-Schorey, C. (2002). Localization and activation of the ARF6 GTPase during cleavage furrow ingression and cytokinesis. J. Biol. Chem. 277, 27210-27216.
    • (2002) J. Biol. Chem , vol.277 , pp. 27210-27216
    • Schweitzer, J.K.1    D'Souza-Schorey, C.2
  • 36
    • 14944365406 scopus 로고    scopus 로고
    • Guanine nucleotide-exchange factors for arf GTPases: Their diverse functions in membrane traffic
    • Shin, H. W. and Nakayama, K. (2004). Guanine nucleotide-exchange factors for arf GTPases: their diverse functions in membrane traffic. J. Biochem. (Tokyo) 136, 761-767.
    • (2004) J. Biochem. (Tokyo) , vol.136 , pp. 761-767
    • Shin, H.W.1    Nakayama, K.2
  • 37
    • 0035978019 scopus 로고    scopus 로고
    • Localization of mRNAs for six ARFs (ADP-ribosylation factors) in the brain of developing and adult rats and changes in the expression in the hypoglossal nucleus after its axotomy
    • Suzuki, I., Owada, Y., Suzuki, R., Yoshimoto, T. and Kondo, H. (2001). Localization of mRNAs for six ARFs (ADP-ribosylation factors) in the brain of developing and adult rats and changes in the expression in the hypoglossal nucleus after its axotomy. Brain Res. Mol. Brain Res. 88, 124-134.
    • (2001) Brain Res. Mol. Brain Res , vol.88 , pp. 124-134
    • Suzuki, I.1    Owada, Y.2    Suzuki, R.3    Yoshimoto, T.4    Kondo, H.5
  • 38
    • 0037203845 scopus 로고    scopus 로고
    • Localization of mRNAs for subfamily of guanine nucleotide-exchange proteins (GEP) for ARFs (ADP-ribosylation factors) in the brain of developing and mature rats under normal and postaxotomy conditions
    • Suzuki, I., Owada, Y., Suzuki, R., Yoshimoto, T. and Kondo, H. (2002). Localization of mRNAs for subfamily of guanine nucleotide-exchange proteins (GEP) for ARFs (ADP-ribosylation factors) in the brain of developing and mature rats under normal and postaxotomy conditions. Brain Res. Mol. Brain Res. 98, 41-50.
    • (2002) Brain Res. Mol. Brain Res , vol.98 , pp. 41-50
    • Suzuki, I.1    Owada, Y.2    Suzuki, R.3    Yoshimoto, T.4    Kondo, H.5
  • 39
    • 3042798296 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway
    • Tague, S. E., Muralidharan, V. and D'Souza-Schorey, C. (2004). ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway. Proc. Natl. Acad. Sci. USA 101, 9671-9676.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 9671-9676
    • Tague, S.E.1    Muralidharan, V.2    D'Souza-Schorey, C.3
  • 40
    • 0030982564 scopus 로고    scopus 로고
    • Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42
    • Threadgill, R., Bobb, K. and Ghosh, A. (1997). Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42. Neuron 19, 625-634.
    • (1997) Neuron , vol.19 , pp. 625-634
    • Threadgill, R.1    Bobb, K.2    Ghosh, A.3
  • 41
    • 0035975972 scopus 로고    scopus 로고
    • Cell motility: ARNO and ARF6 at the cutting edge
    • Turner, C. E. and Brown, M. C. (2001). Cell motility: ARNO and ARF6 at the cutting edge. Curr. Biol. 11, R875-R877.
    • (2001) Curr. Biol , vol.11
    • Turner, C.E.1    Brown, M.C.2
  • 42
    • 0000036684 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 (ARF6) defines two insulin-regulated secretory pathways in adipocytes
    • Yang, C. Z. and Mueckler, M. (1999). ADP-ribosylation factor 6 (ARF6) defines two insulin-regulated secretory pathways in adipocytes. J. Biol. Chem. 274, 25297-25300.
    • (1999) J. Biol. Chem , vol.274 , pp. 25297-25300
    • Yang, C.Z.1    Mueckler, M.2
  • 43
    • 0000645017 scopus 로고    scopus 로고
    • Subcellular distribution and differential expression of endogenous ADP-ribosylation factor 6 in mammalian cells
    • Yang, C. Z., Heimberg, H., D'Souza-Schorey, C., Mueckler, M. M. and Stahl, P. D. (1998). Subcellular distribution and differential expression of endogenous ADP-ribosylation factor 6 in mammalian cells. J. Biol. Chem. 273, 4006-4011.
    • (1998) J. Biol. Chem , vol.273 , pp. 4006-4011
    • Yang, C.Z.1    Heimberg, H.2    D'Souza-Schorey, C.3    Mueckler, M.M.4    Stahl, P.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.