Mepacrine inhibits subepithelial fibrosis by reducing the expression of arginase and TGF-β1 in an extended subacute mouse model of allergic asthma

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 297, Issue 3, 2009, Pages

  Mabalirajan, Ulaganathan ^a   Aich, Jyotirmoi ^a   Agrawal, Anurag ^a   Ghosh, Balaram ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

Author keywords

Lung; Transforming growth factor 1

Indexed keywords

ALLERGEN; ARGINASE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 13; INTERLEUKIN 4; MEPACRINE; OVALBUMIN; PHOSPHOLIPASE A2; TRANSFORMING GROWTH FACTOR BETA1;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOSOL; DRUG DOSE TITRATION; DRUG MECHANISM; EOSINOPHIL; FIBROSIS; GOBLET CELL; IMMUNOLOCALIZATION; IMMUNOREGULATION; INFLAMMATORY CELL; MALE; MEDIATOR; METAPLASIA; MOUSE; NONHUMAN; OPTIMAL DRUG DOSE; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; TH2 CELL;

ANIMALS; ARGINASE; ASTHMA; BRONCHIAL HYPERREACTIVITY; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FIBROSIS; GOBLET CELLS; HYDROXYEICOSATETRAENOIC ACIDS; INFLAMMATION; LUNG; METAPLASIA; MICE; MICE, INBRED BALB C; OVALBUMIN; PHOSPHOLIPASES A2, CYTOSOLIC; QUINACRINE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 68949116242     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00138.2009     Document Type: Article

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