Mechanisms of epidermal growth factor-induced contraction of guinea pig airways

European Journal of Pharmacology

Volumn 296, Issue 2, 1996, Pages 161-168

  Nasuhara, Yasuyuki ^a   Munakata, Mitsuru ^a   Sato, Atsuko ^a   Amishima, Masaru ^a   Homma, Yukihiko ^a   Kawakami, Yoshikazu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

EGF (epidermal growth factor); Leukotriene; Phospholipase A2; Smooth muscle, airway; Tyrosine kinase

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 1,6 HEXAMETHYLENEDICARBAMIC ACID BIS(CYCLOHEXANONE OXIME) ESTER; 15 CYCLOPENTYL 14 OXO 13 AZA 16,17,18,19,20 PENTANORPINANE THROMBOXANE A2; 3 (4 METHOXYPHENYL) 2 [4 [2 (1 PIPERIDINYL)ETHOXY]PHENYL] 2H 1 BENZOPYRAN; CALPHOSTIN C; DIACYLGLYCEROL LIPASE INHIBITOR; DOCEBENONE; EPIDERMAL GROWTH FACTOR; GENISTEIN; IBUPROFEN; INDOMETACIN; K 7; LEUKOTRIENE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOXYGENASE INHIBITOR; MEPACRINE; OZAGREL; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PHOSPHOLIPASE D INHIBITOR; PHOSPHOLIPASE INHIBITOR; PRANLUKAST; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN SYNTHASE INHIBITOR; PROSTANOID; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; THROMBOXANE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG; WORTMANNIN;

AIRWAY CONSTRICTION; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; GUINEA PIG; MALE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; SMOOTH MUSCLE CONTRACTION;

EID: 0030053940     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00692-3     Document Type: Article

References (36)

1. Akiyama, T., J. Ishida, S. Nakagawa, H. Ogawara, S. Watanabe, N. Itoh and M. Shibuya, 1987, Genistein, a specific inhibitor of tyrosine-specific protein kinases, J. Biol. Chem. 262, 5592.
2. Ashida, Y., T. Saijo, H. Kuriki, H. Makino, S. Terao and Y. Maki, 1983, Pharmacological profile of AA-861, a 5-lipoxygenase inhibitor, Prostaglandins 26, 955.
3. Bakhle, Y.S. and S.H. Ferreira, 1985, Lung metabolism of eicosanoids: prostaglandins, prostacyclin, thromboxane, and leukotrienes, in: Handbook of Physiology. The Respiratory System. Circulatory and Nonrespiratory Functions, ed. A.P. Fishman and A.B. Fisher (Am. Physiol. Soc., Bethesda) p. 365.
4. Berk, B.C. and R.W. Alexander, 1989, Vasoactive effects of growth factors, Biochem. Pharmacol. 38, 219.
5. Berk, B.C., T. Brock, R. Webb, M. Taubman, W. Atkinson, M.J. Gimbrone and R. Alexander, 1985, Epidermal growth factor, a vascular smooth muscle mitogen, induces rat aortic contraction, J. Clin. Invest. 75, 1083.
6. Berk, B.C., R. Alexander, T. Brock, M.J. Gimbrone and R. Webb, 1986, Vasoconstriction: A new activity for platelet-derived growth factor, Science 232, 87.
7. Chuang, M. and D.L. Severson, 1990, Inhibition of diacylglycerol metabolism in isolated cardiac myocytes by U-57908 (RHC 80267), a diacylglycerol lipase inhibitor, J. Mol. Cell. Cardiol. 22, 1009.
8. Ebina, M., T. Takahashi, T. Chiba and M. Motomiya, 1993, Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma, Am. Rev. Respir. Dis. 148, 720.
9. Farmer, S., D. Hay, D. Raeburn and J. Fedan, 1987, Relaxation of guinea-pig tracheal smooth muscle to arachidonate is converted to contraction following epithelium removal, Br. J. Pharmacol. 92, 231.
10. 2 activation, Biochem. J. 267, 461.
11. Hidaka, H., M. Inagaki, S. Kawamoto and Y. Sasaki, 1984, Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C, Biochemistry 23, 5036.
12. Hollenberg, M.D., 1993, Growth factors and signal transduction in smooth muscle systems, in: Lung Biology in Health and Disease, Vol. 65, Signal Transduction in Lung Cells, ed. J.S. Brody, D.M. Center, V.A. Tkachuk (Marcel Dekker, New York) p. 369.
13. Kalsner, S. and R. Richards, 1984, Coronary arteries of cardiac patients are hyperreactive and contain stores of amines: a mechanism for coronary spasm, Science 223, 1435.
14. Kanai, F., K. Ito, M. Todaka, H. Hayashi, S. Kamohara, K. Ishii, T. Okada, O. Hazeki, M. Ui and Y. Ebina, 1993, Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase, Biochem. Biophys. Res. Commun. 195, 762.
15. Kaszkin, M., L. Seidler, R. Kast and V. Kinzel, 1992, Epidermal-growth-factor-induced production of phosphatidylalcohols by HeLa cells and A431 cells through activation of phospholipase D, Biochem. J. 287, 51.
16. Kobayashi, E., H. Nakano, M. Morimoto, T. Tamaoki, 1989, Calphostin C (UCN-1028C), A novel microbial compound, is a highly potent and specific inhibitor of protein kinase C, Biochem. Biophys. Res. Commun. 159, 548.
17. 2/prostaglandin endoperoxide receptor, on platelet aggregation and thrombosis, Eur. J. Pharmacol. 163, 253.
18. Majerus, P., T. Connolly, H. Deckmyn, T. Ross, T. Bross, H. Ishii, V. Bansal and D. Wilson, 1986, The metabolism of phosphoinositide-derived messenger molecules, Science 234, 1519.
19. 2 in vasopressin-treated rat glomerular mesangial cells, Biochem. J. 256, 469.
20. Muramatsu, I., M.D. Hollenberg and K. Lederis, 1985, Vascular actions of epidermal growth factor-urogastrone: possible relationship to prostaglandin production, Can. J. Physiol. Pharmacol. 63, 994.
21. Muramatsu, I., M.D. Hollenberg and K. Lederis, 1986, Modulation by epidermal growth factor-urogastrone of contraction in isolated canine helical mesenteric arterial strips, Can. J. Physiol. Pharmacol. 64, 1561.
22. Naito, J., H. Komatsu, A. Ujiie, S. Hamano, T. Kubota and M. Tsuboshima, 1983, Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets, Eur. J. Pharmacol. 91, 41.
23. Patel, P., H. Itoh, K. Lederis and M.D. Hollenberg, 1988, Contraction of guinea pig trachea by epidermal growth factor - urogastrone, Can. J. Physiol. Pharmacol. 66, 1308.
24. Pfeilschifter, J., 1990, Regulatory functions of protein kinase C in glomerular mesangial cells, Klin. Wochenschr. 68, 1134.
25. Reidy, M.A., 1992, Factors controlling smooth-muscle cell proliferation, Arch. Pathol. Lab. Med. 116, 1276.
26. Reinhold, S.L., S.M. Prescott, G.Y. Zimmerman and T.M. McIntyre, 1990, Activation of human neutrophil phospholipase D by three separable mechanisms, FASEB J. 4, 208.
27. Susa, M., D. Vulevic, H.A. Lane and G. Thomas, 1992, Inhibition or down-regulation of protein kinase C attenuates late phase p70s6k activation induced by epidermal growth factor but not by platelet-derived growth factor or insulin, J. Biol. Chem. 267, 6905.
28. 2 and diglyceride lipase, J. Biol. Chem. 257, 14006.
29. Tschirhart, E., N. Frossard, C. Bertrand and Y. Landry, 1987, Arachidonic acid metabolites and airway epithelium-dependent relaxant factor, J. Pharmacol. Exp. Ther. 243, 310.
30. Ullrich, A. and J. Schlessinger, 1990, Signal transduction by receptors with tyrosine kinase activity, Cell 61, 203.
31. Wang, C.G., T. Du, L.J. Xu and J.G. Martin, 1993, Role of leukotriene D4 in allergen-induced increases in airway smooth muscle in the rat, Am. Rev. Respir. Dis. 148, 413.
32. Yamaguchi, T., H. Kohorogi, I. Honda, O. Kawano, M. Sugimoto, S. Araki and M. Ando, 1992, A novel leukotriene antagonist, ONO-1078, inhibits and reverses human bronchial contraction induced by leukotrienes C4 and D4 and antigen in vitro, Am. Rev. Respir. Dis. 146, 923.
33. Yang, S.G. and M.D. Hollenberg, 1991, Distinct receptors for epidermal growth factor-urogastrone in cultured gastric smooth muscle cells, Am. J. Physiol. 260, G827.
34. Yang, S.G., M. Saifeddine, M. Chuang, D. Severson and M.D. Hollenberg, 1991, Diacylglycerol lipase and the contractile action of epidermal growth factor-urogastrone: evidence for distinct signal pathways in a single strip of gastric smooth muscle, Eur. J. Pharmacol. 207, 225.
35. Yang, S.G., M. Saifeddine and M.D. Hollenberg, 1992, Tyrosine kinase inhibitors and the contractile action of epidermal growth factor-urogastrone and other agonists in gastric smooth muscle, Can. J. Physiol. Pharmacol. 70, 85.
36. Yoshimoto, T., C. Yokoyama, K. Ochi, S. Yamamoto, Y. Maki, Y. Ashida, S. Terao and M. Shiraishi, 1982, AA861, a selective inhibitor of the 5-lipoxygenase reaction and the biosynthesis of slow-reacting substance of anaphylaxis, Biochim. Biophys. Acta 713, 470.