-
1
-
-
0035825643
-
Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
-
Abel ED, Peroni O, Kim JK, Kim YB, Boss O, Hadro E, Minnemann T, Shulman GI & Kahn BB (2001). Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature 409, 729 733.
-
(2001)
Nature
, vol.409
, pp. 729-733
-
-
Abel, E.D.1
Peroni, O.2
Kim, J.K.3
Kim, Y.B.4
Boss, O.5
Hadro, E.6
Minnemann, T.7
Shulman, G.I.8
Kahn, B.B.9
-
2
-
-
33846154292
-
Renin receptor expression in human adipose tissue
-
Achard V, Boullu-Ciocca S, Desbriere R, Nguyen G & Grino M (2007). Renin receptor expression in human adipose tissue. Am J Physiol Regul Integr Comp Physiol 292, R274 R282.
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.292
-
-
Achard, V.1
Boullu-Ciocca, S.2
Desbriere, R.3
Nguyen, G.4
Grino, M.5
-
3
-
-
0344373794
-
Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
-
ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial
-
ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (2002). Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 288, 2981 2997.
-
(2002)
JAMA
, vol.288
, pp. 2981-2997
-
-
-
4
-
-
0037160968
-
Cardiovascular morbidity and mortality in the Losartan Intervention for Endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol
-
Dahlof B, Devereux RB, Kjeldsen SE, Julius S, Beevers G, de Faire U, Fyhrquist F, Ibsen H, Kristiansson K, Lederballe-Pedersen O, Lindholm LH, Nieminen MS, Omvik P, Oparil S & Wedel H (2002). Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 359, 995 1003.
-
(2002)
Lancet
, vol.359
, pp. 995-1003
-
-
Dahlof, B.1
Devereux, R.B.2
Kjeldsen, S.E.3
Julius, S.4
Beevers, G.5
De Faire, U.6
Fyhrquist, F.7
Ibsen, H.8
Kristiansson, K.9
Lederballe-Pedersen, O.10
Lindholm, L.H.11
Nieminen, M.S.12
Omvik, P.13
Oparil, S.14
Wedel, H.15
-
5
-
-
33646075100
-
Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan
-
Fan YY, Baba R, Nagai Y, Miyatake A, Hosomi N, Kimura S, Sun GP, Kohno M, Fujita M, Abe Y & Nishiyama A (2006). Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan. Hypertens Res 29, 169 178.
-
(2006)
Hypertens Res
, vol.29
, pp. 169-178
-
-
Fan, Y.Y.1
Baba, R.2
Nagai, Y.3
Miyatake, A.4
Hosomi, N.5
Kimura, S.6
Sun, G.P.7
Kohno, M.8
Fujita, M.9
Abe, Y.10
Nishiyama, A.11
-
6
-
-
39749098706
-
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide
-
Feldt S, Batenburg WW, Mazak I, Maschke U, Wellner M, Kvakan H, Dechend R, Fiebeler A, Burckle C, Contrepas A, Jan Danser AH, Bader M, Nguyen G, Luft FC & Muller DN (2008). Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension 51, 682 688.
-
(2008)
Hypertension
, vol.51
, pp. 682-688
-
-
Feldt, S.1
Batenburg, W.W.2
Mazak, I.3
Maschke, U.4
Wellner, M.5
Kvakan, H.6
Dechend, R.7
Fiebeler, A.8
Burckle, C.9
Contrepas, A.10
Jan Danser, A.H.11
Bader, M.12
Nguyen, G.13
Luft, F.C.14
Muller, D.N.15
-
7
-
-
0033034404
-
Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: The Captopril Prevention Project (CAPPP) randomised trial
-
Hansson L, Lindholm LH, Niskanen L, Lanke J, Hedner T, Niklason A, Luomanmaki K, Dahlof B, de Faire U, Morlin C, Karlberg BE, Wester PO & Bjorck JE (1999). Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial. Lancet 353, 611 616.
-
(1999)
Lancet
, vol.353
, pp. 611-616
-
-
Hansson, L.1
Lindholm, L.H.2
Niskanen, L.3
Lanke, J.4
Hedner, T.5
Niklason, A.6
Luomanmaki, K.7
Dahlof, B.8
De Faire, U.9
Morlin, C.10
Karlberg, B.E.11
Wester, P.O.12
Bjorck, J.E.13
-
8
-
-
0035724736
-
Selective angiotensin II receptor antagonism reduces insulin resistance in obese Zucker rats
-
Henriksen EJ, Jacob S, Kinnick TR, Teachey MK & Krekler M (2001). Selective angiotensin II receptor antagonism reduces insulin resistance in obese Zucker rats. Hypertension 38, 884 890.
-
(2001)
Hypertension
, vol.38
, pp. 884-890
-
-
Henriksen, E.J.1
Jacob, S.2
Kinnick, T.R.3
Teachey, M.K.4
Krekler, M.5
-
9
-
-
9644283069
-
Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin
-
Ichihara A, Hayashi M, Kaneshiro Y, Suzuki F, Nakagawa T, Tada Y, Koura Y, Nishiyama A, Okada H, Uddin MN, Nabi AH, Ishida Y, Inagami T & Saruta T (2004). Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin. J Clin Invest 114, 1128 1135.
-
(2004)
J Clin Invest
, vol.114
, pp. 1128-1135
-
-
Ichihara, A.1
Hayashi, M.2
Kaneshiro, Y.3
Suzuki, F.4
Nakagawa, T.5
Tada, Y.6
Koura, Y.7
Nishiyama, A.8
Okada, H.9
Uddin, M.N.10
Nabi, A.H.11
Ishida, Y.12
Inagami, T.13
Saruta, T.14
-
10
-
-
33750274126
-
Prorenin receptor blockers: Effects on cardiovascular complications of diabetes and hypertension
-
Ichihara A, Kaneshiro Y & Suzuki F (2006a). Prorenin receptor blockers: effects on cardiovascular complications of diabetes and hypertension. Expert Opin Investig Drugs 15, 1137 1139.
-
(2006)
Expert Opin Investig Drugs
, vol.15
, pp. 1137-1139
-
-
Ichihara, A.1
Kaneshiro, Y.2
Suzuki, F.3
-
11
-
-
33748044643
-
Contribution of nonproteolytically activated prorenin in glomeruli to hypertensive renal damage
-
Ichihara A, Kaneshiro Y, Takemitsu T, Sakoda M, Nakagawa T, Nishiyama A, Kawachi H, Shimizu F & Inagami T (2006b). Contribution of nonproteolytically activated prorenin in glomeruli to hypertensive renal damage. J Am Soc Nephrol 17, 2495 2503.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2495-2503
-
-
Ichihara, A.1
Kaneshiro, Y.2
Takemitsu, T.3
Sakoda, M.4
Nakagawa, T.5
Nishiyama, A.6
Kawachi, H.7
Shimizu, F.8
Inagami, T.9
-
12
-
-
33646160993
-
Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension
-
Ichihara A, Kaneshiro Y, Takemitsu T, Sakoda M, Suzuki F, Nakagawa T, Nishiyama A, Inagami T & Hayashi M (2006c). Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension. Hypertension 47, 894 900.
-
(2006)
Hypertension
, vol.47
, pp. 894-900
-
-
Ichihara, A.1
Kaneshiro, Y.2
Takemitsu, T.3
Sakoda, M.4
Suzuki, F.5
Nakagawa, T.6
Nishiyama, A.7
Inagami, T.8
Hayashi, M.9
-
13
-
-
51849092929
-
Angiotensin receptor blockers improve insulin resistance in type 2 diabetic rats by modulating adipose tissue
-
Lee MH, Song HK, Ko GJ, Kang YS, Han SY, Han KH, Kim HK, Han JY & Cha DR (2008). Angiotensin receptor blockers improve insulin resistance in type 2 diabetic rats by modulating adipose tissue. Kidney Int 74, 890 900.
-
(2008)
Kidney Int
, vol.74
, pp. 890-900
-
-
Lee, M.H.1
Song, H.K.2
Ko, G.J.3
Kang, Y.S.4
Han, S.Y.5
Han, K.H.6
Kim, H.K.7
Han, J.Y.8
Cha, D.R.9
-
14
-
-
0035907394
-
Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes
-
Le Lay S, Krief S, Farnier C, Lefrere I, Le Liepvre X, Bazin R, Ferre P & Dugail I (2001). Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes. J Biol Chem 276, 16904 16910.
-
(2001)
J Biol Chem
, vol.276
, pp. 16904-16910
-
-
Le Lay, S.1
Krief, S.2
Farnier, C.3
Lefrere, I.4
Le Liepvre, X.5
Bazin, R.6
Ferre, P.7
Dugail, I.8
-
15
-
-
18544376399
-
Risk of new-onset diabetes in the Losartan Intervention for Endpoint reduction in hypertension study
-
Lindholm LH, Ibsen H, Borch-Johnsen K, Olsen MH, Wachtell K, Dahlof B, Devereux RB, Beevers G, de Faire U, Fyhrquist F, Julius S, Kjeldsen SE, Kristianson K, Lederballe-Pedersen O, Nieminen MS, Omvik P, Oparil S, Wedel H, Aurup P, Edelman JM & Snapinn S (2002). Risk of new-onset diabetes in the Losartan Intervention For Endpoint reduction in hypertension study. J Hypertens 20, 1879 1886.
-
(2002)
J Hypertens
, vol.20
, pp. 1879-1886
-
-
Lindholm, L.H.1
Ibsen, H.2
Borch-Johnsen, K.3
Olsen, M.H.4
Wachtell, K.5
Dahlof, B.6
Devereux, R.B.7
Beevers, G.8
De Faire, U.9
Fyhrquist, F.10
Julius, S.11
Kjeldsen, S.E.12
Kristianson, K.13
Lederballe-Pedersen, O.14
Nieminen, M.S.15
Omvik, P.16
Oparil, S.17
Wedel, H.18
Aurup, P.19
Edelman, J.M.20
Snapinn, S.21
more..
-
16
-
-
0034611678
-
Towards a molecular understanding of adaptive thermogenesis
-
Lowell BB & Spiegelman BM (2000). Towards a molecular understanding of adaptive thermogenesis. Nature 404, 652 660.
-
(2000)
Nature
, vol.404
, pp. 652-660
-
-
Lowell, B.B.1
Spiegelman, B.M.2
-
17
-
-
20544471721
-
Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats
-
Nagai Y, Yao L, Kobori H, Miyata K, Ozawa Y, Miyatake A, Yukimura T, Shokoji T, Kimura S, Kiyomoto H, Kohno M, Abe Y & Nishiyama A (2005). Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats. J Am Soc Nephrol 16, 703 711.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 703-711
-
-
Nagai, Y.1
Yao, L.2
Kobori, H.3
Miyata, K.4
Ozawa, Y.5
Miyatake, A.6
Yukimura, T.7
Shokoji, T.8
Kimura, S.9
Kiyomoto, H.10
Kohno, M.11
Abe, Y.12
Nishiyama, A.13
-
18
-
-
0036266596
-
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
-
Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T & Sraer JD (2002). Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109, 1417 1427.
-
(2002)
J Clin Invest
, vol.109
, pp. 1417-1427
-
-
Nguyen, G.1
Delarue, F.2
Burckle, C.3
Bouzhir, L.4
Giller, T.5
Sraer, J.D.6
-
19
-
-
10544231924
-
Insulin resistance, hyperinsulinemia, and hypertriglyceridemia in the etiology and clinical course of hypertension
-
Reaven GM (1991). Insulin resistance, hyperinsulinemia, and hypertriglyceridemia in the etiology and clinical course of hypertension. Am J Med 90, 7S 12S.
-
(1991)
Am J Med
, vol.90
-
-
Reaven, G.M.1
-
20
-
-
0034881956
-
You are what you secrete
-
Saltiel AR (2001). You are what you secrete. Nat Med 7, 887 888.
-
(2001)
Nat Med
, vol.7
, pp. 887-888
-
-
Saltiel, A.R.1
-
21
-
-
67650236573
-
(Pro)renin receptor-mediated transduction and tissue renin-angiotensin system contribute to diabetes-induced retinal inflammation
-
(in press); DOI: 10.2337/db08-0254.
-
Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y & Ishida S (2009). (Pro)renin receptor-mediated transduction and tissue renin-angiotensin system contribute to diabetes-induced retinal inflammation. Diabetes (in press); DOI : 10.2337/db08-0254.
-
(2009)
Diabetes
-
-
Satofuka, S.1
Ichihara, A.2
Nagai, N.3
Noda, K.4
Ozawa, Y.5
Fukamizu, A.6
Tsubota, K.7
Itoh, H.8
Oike, Y.9
Ishida, S.10
-
22
-
-
42649086029
-
Characterization of a functional (pro)renin receptor in rat brain neurons
-
Shan Z, Cuadra AE, Sumners C & Raizada MK (2008). Characterization of a functional (pro)renin receptor in rat brain neurons. Exp Physiol 93, 701 708.
-
(2008)
Exp Physiol
, vol.93
, pp. 701-708
-
-
Shan, Z.1
Cuadra, A.E.2
Sumners, C.3
Raizada, M.K.4
-
23
-
-
33947502786
-
Relationship between adipocyte size and adipokine expression and secretion
-
Skurk T, Alberti-Huber C, Herder C & Hauner H (2007). Relationship between adipocyte size and adipokine expression and secretion. J Clin Endocrinol Metab 92, 1023 1033.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1023-1033
-
-
Skurk, T.1
Alberti-Huber, C.2
Herder, C.3
Hauner, H.4
-
24
-
-
0037591344
-
Human prorenin has "gate and handle" regions for its non-proteolytic activation
-
Suzuki F, Hayakawa M, Nakagawa T, Nasir UM, Ebihara A, Iwasawa A, Ishida Y, Nakamura Y & Murakami K (2003). Human prorenin has "gate and handle" regions for its non-proteolytic activation. J Biol Chem 278, 22217 22222.
-
(2003)
J Biol Chem
, vol.278
, pp. 22217-22222
-
-
Suzuki, F.1
Hayakawa, M.2
Nakagawa, T.3
Nasir, U.M.4
Ebihara, A.5
Iwasawa, A.6
Ishida, Y.7
Nakamura, Y.8
Murakami, K.9
-
25
-
-
0035171047
-
Effects of cilnidipine on muscle fiber composition, capillary density and muscle blood flow in fructose-fed rats
-
Takada M, Ura N, Higashiura K, Murakami H, Togashi N & Shimamoto K (2001). Effects of cilnidipine on muscle fiber composition, capillary density and muscle blood flow in fructose-fed rats. Hypertens Res 24, 565 572.
-
(2001)
Hypertens Res
, vol.24
, pp. 565-572
-
-
Takada, M.1
Ura, N.2
Higashiura, K.3
Murakami, H.4
Togashi, N.5
Shimamoto, K.6
-
26
-
-
40449086344
-
Skeletal muscle insulin resistance: Role of inflammatory cytokines and reactive oxygen species
-
Wei Y, Chen K, Whaley-Connell AT, Stump CS, Ibdah JA & Sowers JR (2008). Skeletal muscle insulin resistance: role of inflammatory cytokines and reactive oxygen species. Am J Physiol Regul Integr Comp Physiol 294, R673 R680.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.294
-
-
Wei, Y.1
Chen, K.2
Whaley-Connell, A.T.3
Stump, C.S.4
Ibdah, J.A.5
Sowers, J.R.6
-
27
-
-
0035904369
-
Ramipril and the development of diabetes
-
Yusuf S, Gerstein H, Hoogwerf B, Pogue J, Bosch J, Wolffenbuttel BH & Zinman B (2001). Ramipril and the development of diabetes. JAMA 286, 1882 1885.
-
(2001)
JAMA
, vol.286
, pp. 1882-1885
-
-
Yusuf, S.1
Gerstein, H.2
Hoogwerf, B.3
Pogue, J.4
Bosch, J.5
Wolffenbuttel, B.H.6
Zinman, B.7
|