Light-induced aggregation of type I soluble tumor necrosis factor receptor

Journal of Pharmaceutical Sciences

Volumn 98, Issue 9, 2009, Pages 3182-3199

  Roy, Shouvik ^a   Mason, Bruce D ^b   Schöneich, Christian S ^c   Carpenter, John F ^a   Boone, Thomas C ^b   Kerwin, Bruce A ^d  

^a UNIVERSITY OF COLORADO   (United States)

^b AMGEN INC   (United States)

^c UNIVERSITY OF KANSAS   (United States)

^d AMGEN INC   (United States)

Author keywords

Absorption spectroscopy; Biotechnology; Circular dichroism; High performance pressure liquid chromatography (HPLC); Protein aggregation; Protein formulation; Protein structure; Proteins; Stability; UV Vis spectroscopy

Indexed keywords

DIMER; DISULFIDE; GLUTAMINE; METHIONINE; REACTIVE OXYGEN METABOLITE; SUCROSE; TRYPTOPHAN; TUMOR NECROSIS FACTOR RECEPTOR 1;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CIRCULAR DICHROISM; CROSS LINKING; DEOXYGENATION; DISULFIDE BOND; DRUG CONFORMATION; DRUG FORMULATION; ELECTRON; HYDRATION; PH; PHOTOCHEMISTRY; PHOTODEGRADATION; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; REDUCTION; ULTRAVIOLET B RADIATION;

EID: 68949107393     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21750     Document Type: Article

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