Calpain-mediated breakdown of cytoskeletal proteins contributes to cholecystokinin-induced damage of rat pancreatic acini

International Journal of Experimental Pathology

Volumn 90, Issue 4, 2009, Pages 387-399

  Weber, Heike ^a,c   Hühns, Saskia ^a   Lüthen, Frank ^b   Jonas, Ludwig ^c  

^a Laboratory Medicine   (Germany)

^b Department of Internal Medicine ^*  (Germany)

^c UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Acute pancreatitis; Calpain; Calpastatin; Cytoskeletal proteins; Protease activation

Indexed keywords

CALPAIN; CALPAIN 1; CALPAIN 2; CALPASTATIN; CHOLECYSTOKININ; CYTOSKELETON PROTEIN; FLUORESCENT DYE; FODRIN; LACTATE DEHYDROGENASE; UVOMORULIN; VINCULIN;

ACINAR CELL; ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL ISOLATION; CELL LABELING; CELL STIMULATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; ENZYME SUBSTRATE; FEMALE; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; TARGET CELL; TIME SERIES ANALYSIS; ULTRASTRUCTURE ANALYSIS AND ELECTRON MICROSCOPY;

ACTINS; ACUTE DISEASE; ANIMALS; BLOTTING, WESTERN; CADHERINS; CAERULEIN; CALCIUM-BINDING PROTEINS; CALPAIN; CHOLECYSTOKININ; CYSTEINE PROTEINASE INHIBITORS; CYTOSKELETAL PROTEINS; CYTOSKELETON; DIPEPTIDES; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON; MODELS, ANIMAL; ORGAN CULTURE TECHNIQUES; PANCREAS; PANCREATITIS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECTRIN; STIMULATION, CHEMICAL; TIME FACTORS; VINCULIN;

EID: 68849131634     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/j.1365-2613.2009.00638.x     Document Type: Article

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