Translocation of botulinum neurotoxin light chain protease by the heavy chain protein-conducting channel

Toxicon

Volumn 54, Issue 5, 2009, Pages 565-569

  Montal, Mauricio ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Channels; Chaperone; Membranes; Neurotoxicity; Protein translocation

Indexed keywords

BOTULINUM TOXIN; BOTULINUM TOXIN A; BOTULINUM TOXIN E; PROTEINASE; SNARE PROTEIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE TRANSPORT; CHANNEL GATING; CHLOROPLAST; CONFORMATIONAL TRANSITION; ENDOPLASMIC RETICULUM; HEAVY CHAIN; INTRACELLULAR TRANSPORT; LIGHT CHAIN; LIPID BILAYER; MITOCHONDRION; MOLECULAR DYNAMICS; NERVE CELL MEMBRANE CONDUCTANCE; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; TOXIN STRUCTURE;

ANIMALS; BOTULINUM TOXINS; ENDOCYTOSIS; EXOCYTOSIS; HUMANS; ION CHANNELS; MOLECULAR CHAPERONES; NEUROTOXINS; PROTEIN BINDING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SNARE PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SYNAPTIC MEMBRANES;

EID: 68849127717     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.11.018     Document Type: Article

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