메뉴 건너뛰기




Volumn 48, Issue 8, 2009, Pages 742-750

Nuclear import of human MLH1, PMS2, and MutLα: Redundancy is the key

Author keywords

Bipartite NLS; DNA mismatch repair; Human MutL; Human non polyposis colorectal cancer; Nuclear transport

Indexed keywords

MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MUTL; PROTEIN MUTLALPHA; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; DNA BINDING PROTEIN; MLH1 PROTEIN, HUMAN; MUTLALPHA PROTEIN, HUMAN; NUCLEAR PROTEIN; PMS2 PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 68849118239     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20514     Document Type: Article
Times cited : (19)

References (32)
  • 5
    • 24144463165 scopus 로고    scopus 로고
    • Lynch syndrome genes
    • Peltomaki P. Lynch syndrome genes. Fam Cancer 2005;4: 227-232.
    • (2005) Fam Cancer , vol.4 , pp. 227-232
    • Peltomaki, P.1
  • 6
    • 33746189409 scopus 로고    scopus 로고
    • Endonucleolytic Function of MutLalpha in Human Mismatch Repair
    • DOI 10.1016/j.cell.2006.05.039, PII S0092867406008129
    • Kadyrov FA, Dzantiev L, Constantin N, Modrich P. Endonucleolytic function of MutLalpha in human mismatch repair. Cell 2006;126:297-308. (Pubitemid 44092957)
    • (2006) Cell , vol.126 , Issue.2 , pp. 297-308
    • Kadyrov, F.A.1    Dzantiev, L.2    Constantin, N.3    Modrich, P.4
  • 7
    • 0035859003 scopus 로고    scopus 로고
    • HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes
    • Jager AC, Rasmussen M, Bisgaard HC, Singh KK, Nielsen FC, Rasmussen LJ. HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes. Oncogene 2001;20:3590-3595.
    • (2001) Oncogene , vol.20 , pp. 3590-3595
    • Jager, A.C.1    Rasmussen, M.2    Bisgaard, H.C.3    Singh, K.K.4    Nielsen, F.C.5    Rasmussen, L.J.6
  • 9
    • 16344393332 scopus 로고    scopus 로고
    • Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements
    • DOI 10.1073/pnas.0407069102
    • Chen J, Sadowski I. Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements. Proc Natl Acad Sci USA 2005; 102:4813-4818. (Pubitemid 40471536)
    • (2005) Proceedings of the National Academy of Sciences of the United States of America , vol.102 , Issue.13 , pp. 4813-4818
    • Chen, J.1    Sadowski, I.2
  • 13
    • 0037019607 scopus 로고    scopus 로고
    • Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1
    • DOI 10.1016/S1568-7864(02)00079-4, PII S1568786402000794
    • Her C, Vo AT, Wu X. Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1. DNA Repair (Amst) 2002;1:719-729. (Pubitemid 34907869)
    • (2002) DNA Repair , vol.1 , Issue.9 , pp. 719-729
    • Her, C.1    Vo, A.T.2    Wu, X.3
  • 14
    • 0242442569 scopus 로고    scopus 로고
    • Dna Mismatch Repair: Molecular Mechanisms and Biological Function
    • DOI 10.1146/annurev.micro.57.030502.090847
    • Schofield MJ, Hsieh P. DNA mismatch repair: Molecular mechanisms and biological function. Annu Rev Microbiol 2003;57:579-608. (Pubitemid 37406637)
    • (2003) Annual Review of Microbiology , vol.57 , pp. 579-608
    • Schofield, M.J.1    Hsieh, P.2
  • 15
    • 0345357346 scopus 로고    scopus 로고
    • DNA mismatch repair and cancer
    • Li GM. DNA mismatch repair and cancer. Front Biosci 2003; 8:d997-d1017.
    • (2003) Front Biosci , vol.8
    • Li, G.M.1
  • 16
    • 34248572591 scopus 로고    scopus 로고
    • Structure of the Human MutSalpha DNA Lesion Recognition Complex
    • DOI 10.1016/j.molcel.2007.04.018, PII S1097276507002547
    • Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS. Structure of the human MutSalpha DNA lesion recognition complex. Mol Cell 2007;26:579-592. (Pubitemid 46765184)
    • (2007) Molecular Cell , vol.26 , Issue.4 , pp. 579-592
    • Warren, J.J.1    Pohlhaus, T.J.2    Changela, A.3    Iyer, R.R.4    Modrich, P.L.5    Beese, L.6
  • 17
    • 0035477839 scopus 로고    scopus 로고
    • Structure and function of the N-terminal 40 kDa fragment of human PMS2: A monomeric GHL ATpase
    • DOI 10.1093/emboj/20.19.5521
    • Guarné A, Junop MS, Yang W. Structure and function of the N-terminal 40 kDa fragment of human PMS2: A monomeric GHL ATPase. EMBO J 2001;20:5521-5531. (Pubitemid 32959472)
    • (2001) EMBO Journal , vol.20 , Issue.19 , pp. 5521-5531
    • Guarne, A.1    Junop, M.S.2    Yang, W.3
  • 18
    • 0037405122 scopus 로고    scopus 로고
    • Dimerization of MLH1 and PMS2 limits nuclear localization of MutLalpha
    • DOI 10.1128/MCB.23.9.3320-3328.2003
    • WuX, Platt JL, Cascalho M. Dimerization of MLH1 and PMS2 limits nuclear localization of MutLalpha. Mol Cell Biol 2003; 23:3320-3328. (Pubitemid 36459243)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.9 , pp. 3320-3328
    • Wu, X.1    Platt, J.L.2    Cascalho, M.3
  • 22
    • 34247135913 scopus 로고    scopus 로고
    • Classical nuclear localization signals: Definition, function, and interaction with importin alpha
    • DOI 10.1074/jbc.R600026200
    • Lange A, Mills RE, Lange CJ, Stewart M, Devine SE, Corbett AH. Classical nuclear localization signals: Definition, function, and interaction with importin alpha. J Biol Chem 2007; 282:5101-5105. (Pubitemid 47093710)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.8 , pp. 5101-5105
    • Lange, A.1    Mills, R.E.2    Lange, C.J.3    Stewart, M.4    Devine, S.E.5    Corbett, A.H.6
  • 23
    • 0032936125 scopus 로고    scopus 로고
    • Mapping of nuclear localization signals by simultaneous fusion to green fluorescent protein and to beta-galactosidase
    • Sorg G, Stamminger T. Mapping of nuclear localization signals by simultaneous fusion to green fluorescent protein and to beta-galactosidase. Biotechniques 1999;26:858-862. (Pubitemid 129506848)
    • (1999) BioTechniques , vol.26 , Issue.5 , pp. 858-862
    • Sorg, G.1    Stamminger, T.2
  • 26
    • 0029096730 scopus 로고
    • A hPMS2 mutant cell line is defective in strand-specific mismatch repair
    • Risinger JI, Umar A, Barrett JC, Kunkel TA. A hPMS2 mutant cell line is defective in strand-specific mismatch repair. J Biol Chem 1995;270:18183-18186.
    • (1995) J Biol Chem , vol.270 , pp. 18183-18186
    • Risinger, J.I.1    Umar, A.2    Barrett, J.C.3    Kunkel, T.A.4
  • 28
    • 0026078249 scopus 로고
    • Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
    • Robbins J, Dilworth SM, Laskey RA, Dingwall C. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence. Cell 1991;64:615-623. (Pubitemid 121002977)
    • (1991) Cell , vol.64 , Issue.3 , pp. 615-623
    • Robbins, J.1    Dilworth, S.M.2    Laskey, R.A.3    Dingwall, C.4
  • 29
    • 18244428910 scopus 로고    scopus 로고
    • Characterization of the bipartite nuclear localization signal of protein LANA2 from Kaposi's sarcoma-associated herpesvirus
    • DOI 10.1042/BJ20021890
    • Munoz-Fontela C, Rodriguez E, Nombela C, Arroyo J, Rivas C. Characterization of the bipartite nuclear localization signal of protein LANA2 from Kaposi's sarcoma-associated herpesvirus. Biochem J 2003;374:545-550. (Pubitemid 37094115)
    • (2003) Biochemical Journal , vol.374 , Issue.2 , pp. 545-550
    • Munoz-Fontela, C.1    Rodriguez, E.2    Nombela, C.3    Arroyo, J.4    Rivas, C.5
  • 30
    • 38149104520 scopus 로고    scopus 로고
    • Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutLalpha
    • Sacho EJ, Kadyrov FA, Modrich P, Kunkel TA, Erie DA. Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutLalpha. Mol Cell 2008;29: 112-121.
    • (2008) Mol Cell , vol.29 , pp. 112-121
    • Sacho, E.J.1    Kadyrov, F.A.2    Modrich, P.3    Kunkel, T.A.4    Erie, D.A.5
  • 31
    • 0036479106 scopus 로고    scopus 로고
    • Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast MLH1 and PMS1 proteins
    • Hall MC, Shcherbakova PV, Kunkel TA. Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast MLH1 and PMS1 proteins. J Biol Chem 2002;277:3673-3679.
    • (2002) J Biol Chem , vol.277 , pp. 3673-3679
    • Hall, M.C.1    Shcherbakova, P.V.2    Kunkel, T.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.