메뉴 건너뛰기




Volumn 77, Issue 4, 2009, Pages 301-308

New drug, fospropofol disodium: A propofol prodrug

Author keywords

2,6 Diisopropylphenoxymethyl phosphate disodium salt; Fospropofol disodium; Lipid based emulsion; Prodrug; Propofol

Indexed keywords

FENTANYL; FORMALDEHYDE; FORMIC ACID; FOSPROPOFOL; LUSEDRA; MIDAZOLAM; MORPHINE; PETHIDINE; PHENOL DERIVATIVE; PHOSPHATIDYLCHOLINE; PROPOFOL; SOYBEAN OIL; UNCLASSIFIED DRUG;

EID: 68849113228     PISSN: 00946354     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (20)

References (45)
  • 1
    • 0345283348 scopus 로고    scopus 로고
    • Physicochemical compatibility of propofol-lidocaine mixture
    • Masaki Y, Tanaka M, Nishikawa T. Physicochemical compatibility of propofol-lidocaine mixture. Anesth Analg. 2003;97(6):1646-1651.
    • (2003) Anesth Analg , vol.97 , Issue.6 , pp. 1646-1651
    • Masaki, Y.1    Tanaka, M.2    Nishikawa, T.3
  • 2
    • 0029792136 scopus 로고    scopus 로고
    • The effect of the addition of lignocaine on propofol emulsion stability
    • Lilley EMM, Isert PR, Carraso ML, Kennedy RA. The effect of the addition of lignocaine on propofol emulsion stability. Anaesthesia. 1996;51(9):815-818. (Pubitemid 26305857)
    • (1996) Anaesthesia , vol.51 , Issue.9 , pp. 815-818
    • Lilley, E.M.M.1    Isert, P.R.2    Carasso, M.L.3    Kennedy, R.A.4
  • 3
    • 0041327901 scopus 로고    scopus 로고
    • The effect of lidocaine on the globule size distribution of propofol emulsions
    • Park JW, Park ES, Chi SC, Kil HY, Lee KH. The effect of lidocaine on the globule size distribution of propofol emulsions. Anesth Analg. 2003;97(3):769-771.
    • (2003) Anesth Analg , vol.97 , Issue.3 , pp. 769-771
    • Park, J.W.1    Park, E.S.2    Chi, S.C.3    Kil, H.Y.4    Lee, K.H.5
  • 4
    • 0035857697 scopus 로고    scopus 로고
    • Physical properties and stability of two emulsion formulations of propofol
    • DOI 10.1016/S0378-5173(00)00692-X, PII S037851730000692X
    • Han J, Davis SS, Washington C. Physical properties and stability of two emulsion formulations of propofol. Int J Pharm. 2001;215(1-2):207-220. (Pubitemid 32206618)
    • (2001) International Journal of Pharmaceutics , vol.215 , Issue.1-2 , pp. 207-220
    • Han, J.1    Davis, S.S.2    Washington, C.3
  • 6
    • 34249056453 scopus 로고    scopus 로고
    • Microbial growth in propofol formulations with disodium edetate and the influence of venous access system dead space
    • DOI 10.1111/j.1365-2044.2007.05002.x
    • Fukada T, Osaki M. Microbial growth in propofol formulations with disodium edetate and the influence of venous access system dead space. Anaesthesia. 2007;62(6):575-580. (Pubitemid 46796318)
    • (2007) Anaesthesia , vol.62 , Issue.6 , pp. 575-580
    • Fukada, T.1    Ozaki, M.2
  • 7
    • 0029001266 scopus 로고
    • Postoperative infections traced to an intravenous anesthetic, propofol
    • Bennett SN, McNeil MM, Bland LA, et al. Postoperative infections traced to an intravenous anesthetic, propofol. N Engl J Med. 1995;333(3):147-154.
    • (1995) N Engl J Med , vol.333 , Issue.3 , pp. 147-154
    • Bennett, S.N.1    McNeil, M.M.2    Bland, L.A.3
  • 8
    • 0027406606 scopus 로고
    • Propofol vs midazolam in short-, medium-, and long-term sedation of critically ill patients; a cost-benefit analysis
    • Carrasko G, Molina R, Costa J, Soler JM, Cabré L. Propofol vs midazolam in short-, medium-, and long-term sedation of critically ill patients: A cost-benefit analysis. Chest. 1993;103(2):557-564. (Pubitemid 23070763)
    • (1993) Chest , vol.103 , Issue.2 , pp. 557-564
    • Carrasco, G.1    Molina, R.2    Costa, J.3    Soler, J.-M.4    Cabre, L.5
  • 11
    • 15944403233 scopus 로고    scopus 로고
    • Plasma triglycerides and type III hyperlipidemia are independently associated with premature familial coronary artery disease
    • DOI 10.1016/j.jacc.2004.11.062
    • Hopkins P, Wu L, Hunt S, Brinton E. Plasma triglycerides and type III hyperlipidemia are independently associated with premature familial coronary artery disease. J Am Coll Cardiol. 2005;45(7):1003-1012. (Pubitemid 40432430)
    • (2005) Journal of the American College of Cardiology , vol.45 , Issue.7 , pp. 1003-1012
    • Hopkins, P.N.1    Wu, L.L.2    Hunt, S.C.3    Brinton, E.A.4
  • 14
    • 34447330134 scopus 로고    scopus 로고
    • Development of a new generation of propofol
    • DOI 10.1097/ACO.0b013e3281667777, PII 0000150320070800000006
    • Wang H, Cork R, Rao A. Development of a new generation of propofol. Curr Opin Anaesthesiol. 2007;20(4):311-315. (Pubitemid 47051890)
    • (2007) Current Opinion in Anaesthesiology , vol.20 , Issue.4 , pp. 311-315
    • Wang, H.1    Cork, R.2    Rao, A.3
  • 15
    • 0041343200 scopus 로고    scopus 로고
    • Pharmacokinetics and clinical pharmacodynamics of the new propofol prodrug GPI 15715 in volunteers
    • published correction appears in Anesthesiology. 2008;109(5):940
    • Fechner J, Ihmsen H, Hatterschild D, et al. Pharmacokinetics and clinical pharmacodynamics of the new propofol prodrug GPI 15715 in volunteers [published correction appears in Anesthesiology. 2008;109(5):940]. Anesthesiology. 2003;99(2):303-313.
    • (2003) Anesthesiology , vol.99 , Issue.2 , pp. 303-313
    • Fechner, J.1    Ihmsen, H.2    Hatterschild, D.3
  • 16
    • 0001199533 scopus 로고
    • Chemical aspects of selective toxicity
    • Albert A. Chemical aspects of selective toxicity. Nature. 1958;182(4633):421-422.
    • (1958) Nature , vol.182 , Issue.4633 , pp. 421-422
    • Albert, A.1
  • 17
  • 18
    • 84867794009 scopus 로고    scopus 로고
    • Water soluble prodrugs of hindered alcohols
    • Stella V, Zygmunt JJ, Georg IG, Safadi MS, inventors; University of Kansas, assignee. US patent 7,244,718. July 17, Accessed May 16, 2008
    • Stella V, Zygmunt JJ, Georg IG, Safadi MS, inventors; University of Kansas, assignee. Water soluble prodrugs of hindered alcohols. US patent 7,244,718. July 17, 2007. http://patft.uspto.gov/netacgi/nph-Parser?Sect1= PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum. htm&r=1&f=G&1=50&s1=7244718.PN.&OS=PN/7244718&RS=PN/ 7244718. Accessed May 16, 2008.
    • (2007)
  • 20
    • 26244464421 scopus 로고    scopus 로고
    • AQUAVAN injection, a water-soluble prodrug of propofol, as a bolus injection: A phase I dose-escalation comparison with DIPRIVAN, part 2: pharmacodynamics and safety
    • published correction appears in Anesthesiology. 2008;109(5):940
    • Struys MMRF, Vanluchene ALG, Gibiansky E, et al. AQUAVAN injection, a water-soluble prodrug of propofol, as a bolus injection: a phase I dose-escalation comparison with DIPRIVAN, part 2: pharmacodynamics and safety [published correction appears in Anesthesiology. 2008;109(5):940]. Anesthesiology. 2005;103(4):730-743.
    • (2005) Anesthesiology , vol.103 , Issue.4 , pp. 730-743
    • Struys, M.M.R.F.1    Vanluchene, A.L.G.2    Gibiansky, E.3
  • 21
    • 0002942853 scopus 로고
    • Biochemical role of folate in cellular metabolism
    • Bailey LB, ed. New York, NY: Marcel Dekker
    • Wagner C. Biochemical role of folate in cellular metabolism. In: Bailey LB, ed. Folate in Health and Disease. New York, NY: Marcel Dekker; 1995:23-42.
    • (1995) Folate in Health and Disease , pp. 23-42
    • Wagner, C.1
  • 22
    • 26244438839 scopus 로고    scopus 로고
    • AQUAVAN injection, a water-soluble prodrug of propofol, as a bolus injection: A phase I dose-escalation comparison with DIPRIVAN, part 1: pharmacokinetics
    • published correction appears in Anesthesiology. 2008;109(5):940
    • Gibiansky E, Struys MMRF, Gibiansky L, et al. AQUAVAN injection, a water-soluble prodrug of propofol, as a bolus injection: a phase I dose-escalation comparison with DIPRIVAN, part 1: pharmacokinetics [published correction appears in Anesthesiology. 2008;109(5):940]. Anesthesiology. 2005;103(4):718-729.
    • (2005) Anesthesiology , vol.103 , Issue.4 , pp. 718-729
    • Gibiansky, E.1    Struys, M.M.R.F.2    Gibiansky, L.3
  • 23
    • 55749109196 scopus 로고    scopus 로고
    • Your prodrug releases formaldehyde: Should you be concerned? No!
    • Dharshwar SS, Stella VJ. Your prodrug releases formaldehyde: should you be concerned? No! J Pharm Sci. 2008;97(10):4184-4193.
    • (2008) J Pharm Sci , vol.97 , Issue.10 , pp. 4184-4193
    • Dharshwar, S.S.1    Stella, V.J.2
  • 24
    • 4344681198 scopus 로고    scopus 로고
    • Comparative pharmacokinetics and pharmacodynamics of the new propofol prodrug GPI 15715 and propofol emulsion
    • published correction appears in Anesthesiology. 2008;109(5):940
    • Fechner J, Ihmsen H, Hatterschild D, et al. Comparative pharmacokinetics and pharmacodynamics of the new propofol prodrug GPI 15715 and propofol emulsion [published correction appears in Anesthesiology. 2008;109(5):940]. Anesthesiology. 2004;101(3):626-639.
    • (2004) Anesthesiology , vol.101 , Issue.3 , pp. 626-639
    • Fechner, J.1    Ihmsen, H.2    Hatterschild, D.3
  • 26
    • 0024563476 scopus 로고
    • Effect of prolonged sedation with propofol on serum triglyceride and cholesterol concentrations
    • Gottardis M, Khünl-Brady KS, Koller W, Sigl G, Hackl JM. Effect of prolonged sedation with propofol on serum triglyceride and cholesterol concentrations. Br J Anaesth. 1989;62(4):393-396. (Pubitemid 19111719)
    • (1989) British Journal of Anaesthesia , vol.62 , Issue.4 , pp. 393-396
    • Gottardis, M.1    Khunl-Brady, K.S.2    Koller, W.3    Sigl, G.4    Hackl, J.M.5
  • 27
    • 0022394457 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic modeling of propofol (Diprivan) in volunteers and surgical patients
    • Schüttler J, Stoeckel H, Schwilden H. Pharmacokinetic and pharmacodynamic modeling of propofol (Diprivan) in volunteers and surgical patients. Postgrad Med J. 2005;61(suppl 3):53-54.
    • (2005) Postgrad Med J , vol.61 , Issue.SUPPL. 3 , pp. 53-54
    • Schüttler, J.1    Stoeckel, H.2    Schwilden, H.3
  • 33
    • 52149109838 scopus 로고    scopus 로고
    • Patient and physician satisfaction with fospropofol disodium: Results of a phase 3, randomized, double-blind trial evaluating fospropofol disodium for moderate sedation in patients undergoing colonoscopy
    • abstract Abstract W1440
    • Cohen LB, Rex DK, Kline J, Wang C. Patient and physician satisfaction with fospropofol disodium: results of a phase 3, randomized, double-blind trial evaluating fospropofol disodium for moderate sedation in patients undergoing colonoscopy [abstract]. Gastrointest Endosc. 2007;65(5):AB367. Abstract W1440.
    • (2007) Gastrointest Endosc , vol.65 , Issue.5
    • Cohen, L.B.1    Rex, D.K.2    Kline, J.3    Wang, C.4
  • 34
    • 52949143283 scopus 로고    scopus 로고
    • Fospropofol disodium for minimal-to-moderate sedation during colonoscopy produces clear-headed recovery: Results of a phase 3, randomized, double-blind trial
    • abstract Abstract W1441
    • Rex DK, Cohen LB, Kline J, Wang C. Fospropofol disodium for minimal-to-moderate sedation during colonoscopy produces clear-headed recovery: results of a phase 3, randomized, double-blind trial [abstract]. Gastrointest Endosc. 2007;65(5):AB367. Abstract W1441.
    • (2007) Gastrointest Endosc , vol.65 , Issue.5
    • Rex, D.K.1    Cohen, L.B.2    Kline, J.3    Wang, C.4
  • 35
    • 52149110461 scopus 로고    scopus 로고
    • Fospropofol disodium is effective and safe for minimal to moderate sedation in patients undergoing colonoscopy: Results of a phase 3, randomized, double-blind trial
    • abstract Abstract W1451
    • Rex DK, Cohen LB, Kline J, Wang C. Fospropofol disodium is effective and safe for minimal to moderate sedation in patients undergoing colonoscopy: results of a phase 3, randomized, double-blind trial [abstract]. Gastrointest Endosc. 2007;65(5):AB369. Abstract W1451.
    • (2007) Gastrointest Endosc , vol.65 , Issue.5
    • Rex, D.K.1    Cohen, L.B.2    Kline, J.3    Wang, C.4
  • 36
    • 68849087644 scopus 로고    scopus 로고
    • A phase 1, double-blind, placebo-controlled, parallel-design, drug interaction study of fospropofol disodium (FD) and premedication in healthy, adult subjects
    • Abstract T1327
    • Vornov J, Braitman D, Gibiansky E, Jones J. A phase 1, double-blind, placebo-controlled, parallel-design, drug interaction study of fospropofol disodium (FD) and premedication in healthy, adult subjects. Gastrointest Endosc. 2006;63(5):AB195. Abstract T1327.
    • (2006) Gastrointest Endosc , vol.63 , Issue.5
    • Vornov, J.1    Braitman, D.2    Gibiansky, E.3    Jones, J.4
  • 37
    • 0025720595 scopus 로고
    • Results from the American Society for Gastrointestinal Endoscopy/US Food and Drug Administration collaborative study on complication rates and drug use during gastrointestinal endoscopy
    • Arrowsmith JB, Gerstman BB, Fleischer DE, Benjamin SB. Results from the American Society for Gastrointestinal Endoscopy/US Food and Drug Administration collaborative study on complication rates and drug use during gastrointestinal endoscopy. Gastrointest Endosc. 1991;37(4):421-427.
    • (1991) Gastrointest Endosc , vol.37 , Issue.4 , pp. 421-427
    • Arrowsmith, J.B.1    Gerstman, B.B.2    Fleischer, D.E.3    Benjamin, S.B.4
  • 38
    • 13844314805 scopus 로고    scopus 로고
    • From oral midazolam to propofol: A perspective
    • DOI 10.1016/S0016-5107(04)02800-7, PII S0016510704028007
    • Geller E. From oral midazolam to propofol: a perspective [editorial]. Gastrointest Endosc. 2005;61(2):201-202. (Pubitemid 40261066)
    • (2005) Gastrointestinal Endoscopy , vol.61 , Issue.2 , pp. 201-203
    • Geller, E.1
  • 39
    • 35748935548 scopus 로고    scopus 로고
    • Use of lipid emulsion to reverse local anesthetic-induced toxicity
    • Corman SL, Skledar SL. Use of lipid emulsion to reverse local anesthetic-induced toxicity. Ann Pharmacother. 2007;41(11):1873-1877.
    • (2007) Ann Pharmacother , vol.41 , Issue.11 , pp. 1873-1877
    • Corman, S.L.1    Skledar, S.L.2
  • 40
    • 33646704187 scopus 로고    scopus 로고
    • Lipid emulsion to treat overdose of local anaesthetic [3]
    • DOI 10.1111/j.1365-2044.2006.04664-1.x
    • Moore N, Kirton C, Bane J. Lipid emulsion to treat overdose of local anaesthetic [letter]. Anaesthesia. 2006;61(6):607. (Pubitemid 43740723)
    • (2006) Anaesthesia , vol.61 , Issue.6 , pp. 607
    • Moore, N.1    Kirton, C.2    Bane, J.3
  • 43
    • 0022656441 scopus 로고
    • More on dexamethasone-induced perineal irritation
    • letter
    • Thomas VL. More on dexamethasone-induced perineal irritation [letter]. N Engl J Med. 1986;314(25):1643-1644.
    • (1986) N Engl J Med , vol.314 , Issue.25 , pp. 1643-1644
    • Thomas, V.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.