Pharmacological perspectives of wasp venom

Protein and Peptide Letters

Volumn 16, Issue 8, 2009, Pages 944-952

  Monteiro, Marta C ^a,d   Romão, Pedro R T ^b   Soares, Andreimar M ^c  

^a Instituto de Ciências da Saúde   (Brazil)

^b UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d FEDERAL UNIVERSITY OF PARÁ   (Brazil)

Author keywords

Allergens; Biological activity; Hymenoptera venom; Wasp venom

Indexed keywords

ALLERGEN; INSECT PROTEIN; NEUROTOXIN; PHOSPHOLIPASE; WASP VENOM;

ANIMAL; ARTICLE; ENZYMOLOGY; HUMAN; IMMUNOLOGY; WASP;

ALLERGENS; ANIMALS; HUMANS; INSECT PROTEINS; NEUROTOXINS; PHOSPHOLIPASES; WASP VENOMS; WASPS;

ANIMALIA; HYMENOPTERA;

EID: 68849109952     PISSN: 09298665     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986609788923275     Document Type: Article

References (176)

1. Habermann, E. Bee and wasp venoms. Science, 1972, 177(46), 314-322.
2. Nakajima, T. Biochemistry of vespid venoms. In Handbook of Natural Toxins. Tu, A. T.; Ed.; Marcel Dekker, New York, 1984, 2, pp. 109-133.
3. Nakajima, T. Pharmacological biochemistry of vespid venoms. In Venoms of the Hymenoptera, Piek, T.; Ed.; Academic Press.; London, 1986, pp. 309-327.
4. Banks, B. E. C. Shipolini, R. A. Chemistry and pharmacology of honey-bee venom. In Venoms of the Hymenoptera, Biochemical, Pharmacological and Behavioural Aspects Piek T.; Ed.; Orlando, FL: Academic Press, 1986, pp. 329-416.
5. Schmidt, J. O. Chemistry, pharmacology and chemical ecology of ant venoms. In Venoms of the Hymenoptera. Biochemical, Pharmacological and Behavioural Aspects Piek T.; ed.; Orlando, Florida: Academic Press, 1986, pp. 425-508.
6. Lichtenstein, L. M. Valentine, M. D. Sobotka, A. K. Insect allergy: the state of the art. J. Allergy Clin. Immunol., 1979, 64(1), 5-12.
7. Hoffman, D. R. Allergens in Hymenoptera venom XV: The immunologic basis of vespid venom cross-reactivity. J. Allergy Clin. Immunol.; 1985, 75(5), 611-613.
8. Reisman, R. E. Osur, S. L. Allergic reactions following first insect sting exposure. Ann. Allergy, 1987, 59(6), 429-432.
9. Müller, U. R. Insect sting allergy Clinical Picture, Diagnosis, and Treatment. Gustav Fischer Verlag, Ed.; Stuttgart-New York, 1990.
10. King, T. P. Guralnick, M. Hymenoptera allergens, In Allergens and Allergen Immunotherapy. Lockey R, Bukantz S, Bousquet J. Eds. Marcel Dekker, New York, 2004, pp 339-354.
11. Hoffman, D. R. Hymenoptera venom allergens. Clin. Rev. Allergy Immunol., 2006, 30(2), 109-128.
12. Golden, D. B. Marsh, D. G. Freidhoff, L. R. Kwiterovich, K. A. Addison, B. Kagey-Sobotka, A. Lichtenstein, L. M. Natural history of Hymenoptera venom sensitivity in adults. J. Allergy Clin. Immunol., 1997, 100 (6 Pt 1), 760-766. (Pubitemid 28298993)
13. Antonicelli, L. Bilo, M. B. Bonifazi, F. Epidemiology of Hymenoptera allergy. Curr. Opin. Allergy Clin. Immunol.; 2002, 2(4), 341-346. (Pubitemid 36869643)
14. Vachvanichsanong, P. Dissaneewate, P. Mitarnun, W. Non-fatal acute renal failure due to wasp stings in children. Pediatr. Nephrol., 1997, 11(6), 734-736. (Pubitemid 27520540)
15. Daher Ede, F. da Silva Júnior, G. B. Bezerra, G. P. Pontes, L. B. Martins, A. M. Guimarães, J. A. Acute renal failure after massive honeybee stings. Rev. Inst. Med. Trop. Sao Paulo, 2003, 45(1), 45-50. (Pubitemid 36331514)
16. De Bandt, M.; Atassi-Dumont, M. Kahn, M. F. Herman, D. J. Serum sickness after wasp venom immunotherapy: clinical and biological study. J. Rheumatol., 1997, 24(6), 1195-1197. (Pubitemid 27250133)
17. Creange, A. Saint-Val, C. Guillevin, L. Degos, J. D, Gherardi, R. Peripheral neuropathies after arthropod stings not due to Lyme disease: a report of five cases and review of the literature. Neurology, 1993, 43(8), 1483-1488. (Pubitemid 23230529)
18. Boz, C. Velioglu, S. Ozmenoglu M. Acute disseminated encephalomyelitis after bee sting. Neurol. Sci., 2003, 23(6), 313-315. (Pubitemid 36336062)
19. Biló, B. M. Rueff, F. Mosbech, H. Bonifazi, F. Oude-Elberink, J. N. the EAACI Interest Group on Insect Venom Hypersensitivity. Diagnosis of Hymenoptera venom allergy. Allergy, 2005, 60(11), 1339-1349.
20. Hoffman, D. R. Allergens in hymenoptera venom. V. Identification of some of the enzymes and demonstration of multiple allergens in yellow jacket venom. Ann. Allergy, 1978, 40(3), 171-176.
21. Hoffman, D. R. Allergens in Hymenoptera venom. XXV: The amino acid sequences of antigen 5 molecules and the structural basis of antigenic cross-reactivity. J. Allergy Clin. Immunol., 1993, 92(5), 707-716. (Pubitemid 2014796)
22. King, T. P. Spangfort, M. D. Structure and biology of stinging insect venom allergens. Int. Arch. Allergy Immunol., 2000, 123(2), 99-106.
23. King, T. P. Sobotka, A. K. Kochoumian, L. Lichtenstein, L. M. Allergens of honey bee venom. Arch. Biochem. Biophys., 1976, 172(2), 661-671.
24. Kettner, A. Hughes, G. J. Frutiger, S. Astori, M. Roggero, M. Spertini, F. Corradin, G. Api m 6: a new bee venom allergen. J. Allergy Clin. Immunol., 2001, 107(5), 914-920. (Pubitemid 32436928)
25. Hoffman, D. R. Jacobson, R. S. Allergens in hymenoptera venom XII: how much protein is in a sting? Ann. Allergy, 52, 1984, (4), 276-278.
26. Schumacher, M. J. Tveten, M. S. Egen, N. B. Rate and quantity of delivery of venom from honeybee stings. J. Allergy Clin. Immunol., 1994, 93(5), 831-835.
27. Schumacher, M. J. Schmidt, J. O. Egen, N. B. Dillon, K. A. Biochemical variability of venoms from individual European and Africanized honeybees (Apis mellifera). J. Allergy Clin. Immunol., 1992, 90(1), 59-65.
28. Edery, H. Ishay, J. Gitter, S. Joshua, H. Venom of Vespidae. In Arthropod venoms. Bettini S, ed. Berlin, New York, USA: Sprinter Verlag, 1978, pp. 691-771.
29. Evans, R. E. Summers, R. J. Clinical aspects of Hymenoptera hypersensitivity In Monograph on insect allergy M. I. Levine & R. F. Lockey, eds. Pittsburgh, Pennsylvania, USA, American Academy of Allergy and Immunology, 1986, pp. 23-28.
30. Sakhuja, V. Bhalla, A. Pereira, B. J. Kapoor, M. M. Bhusnurmath, S. R. Chugh, K. S. Acute renal failure following multiple hornet stings. Nephron, 1988, 49(4), 319-321. (Pubitemid 18168813)
31. Korman, S. H. Jabbour, S. Harari, M. D. Multiple hornet (Vespa orientalis) stings with fatal outcome in a child. J. Paediatr. Child. Health, 1990, 26(5), 283-285.
32. Fernandez, J. Rodes, F. Marti, J. Blanca, M. Wasp sting anaphylaxis as a cause of death: a case report. Allergol. Immunopathol. (Madr), 1992, 20(1), 40-41.
33. Watemberg, N. Weizman, Z. Shahak, E. Aviram, M. Maor, E. Fatal multiple organ failure following massive hornet stings. J. Toxicol. Clin. Toxicol., 1995, 33(5), 471-474.
34. Chao, S. C. Lee, Y. Y. Acute rhabdomyolysis and intravascular hemolysis following extensive wasp stings. Int. J. Dermatol., 1999, 38(2), 135-137.
35. Chen, D. M. Lee, P. T. Chou, K. J. Fang, H. C. Chung, H. M. Chen, D. M. Chang, L. K. Descending aortic thrombosis and cerebral infarction after massive wasp stings. Am. J. Med., 2004, 116(8), 567-569.
36. Piek T. Pharmacology of hymenoptera venom in Handbook of Natural Toxins. Tu, A. T.; Ed. Marcel Dekker, New York, 1984, 2, pp. 135-185.
37. Johansson, S. G. Hourihane, J. O. Bousquet, J. Bruijnzeel-Koomen, C. Dreborg, S. Haahtela, T. Kowalski, M. L. Mygind, N. Ring, J. van Cauwenberge, P.; van Hage-Hamsten, M.; Wüthrich, B. EAACI (the European Academy of Allergology and Cinical Immunology) nomenclature task force. A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force. Allergy, 2001, 56(9), 813-824.
38. Reisman, R. E. Livingston, A. Venom immunotherapy:10 years of experience with administration of single venoms and 50 micrograms maintenance doses. J. Allergy Clin. Immunol., 1992, 89(6), 1189-1195.
39. Muller, U. R. New developments in the diagnosis and treatment of hymenoptera venom allergy. Int. Arch. Allergy Immunol., 2001, 124(4), 447-453. (Pubitemid 32429687)
40. Bousquet, J. Lockey, R. Malling, H. J. Allergen immunotherapy: therapeutic vaccines for allergic diseases. A WHO position paper. J. Allergy Clin. Immunol., 1998, 102 (4 Pt 1), 558-562. (Pubitemid 28487930)
41. Bellinghausen, I. Klostermann, B. Böttcher, I. Knop, J. Saloga, J. Importance of the inducible costimulator molecule for the induction of allergic immune responses and its decreased expression on T helper cells after venom immunotherapy. Immunology, 2004, 112(1), 80-86. (Pubitemid 38609825)
42. Levings, M. K. Sangregorio, R. Galbiati, F. Squadrone, S. de Waal Malefyt, R. Roncarolo, M. G. IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells. J. Immunol., 2001, 166(9), 5530-5539. (Pubitemid 32374175)
43. Mamessier, E. Birnbaum, J. Dupuy, P. Vervloet, D. Magnan, A. Ultra-rush venom immunotherapy induces differential T cell activation and regulatory patterns according to the severity of allergy. Clin. Exp. Allergy, 2006, 36(6), 704-713. (Pubitemid 43972965)
44. Reisman, R. E. Muller, U. R. Wypych, J. I. Lazell, M. I. Studies of coexisting honeybee and vespid-venom sensitivity. J. Allergy Clin. Immunol., 1984, 73(2), 246-252.
45. Backman, A. Belin, L. Dreborg, S. Halvorsen, R. Malling, H. J. Weeke, B. Standardization of allergenic preparations. Comments with reference to the second edition of the common Nordic guidelines for registration of allergenic preparations. Allergy, 1991, 46(2), 81-84.
46. Muller, U. R. Hymenoptera venom hypersensitivity: an update. Clin. Exp. Allergy, 1998, 28(1), 4-6.
47. Littler, S. Wypych, J. I. Noble, R. W. Abeyounis, C. J. Reisman, R. E. Allergenic components of bald-faced hornet (V. maculata) venom. Int. Arch. Allergy Appl. Immunol., 1985, 76(1), 1-8. (Pubitemid 15155480)
48. Dudler, T. Machado, D. C. Kolbe, L. Annand, R. R. Rhodes, N. Gelb, M. H. Koelsch, K. Suter, M. Helm, B. A. A link between catalytic activity, IgE-independent mast cell activation, and allergenicity of bee venom phospholipase A2. J. Immunol., 1995, 155(5), 2605-2613.
49. Machado, D. C. Horton, D. Harrop, R. Peachell, P. T. Helm, B. A. Potential allergens stimulate the release of mediators of the allergic response from cells of mast cell lineage in the absence of sensitization with antigen-specific IgE. Eur. J. Immunol., 1996, 26(12), 2972-2980. (Pubitemid 26411502)
50. King, T. P. Sobotka, A. K. Alagon, A. Kochoumian, L. Lichtenstein, L. M. Protein allergens of white-faced hornet, yellow hornet, and yellow jacket venoms. Biochemistry, 1978, 17(24), 5165-5174. (Pubitemid 9063056)
51. Cascone, O. Amaral, V. Ferrara, P. Vita, N. Guillemot, J. C. Díaz, L. E. Purification and characterization of two forms of antigen 5 from polybia scutellaris venom. Toxicon, 1995, 33(5), 659-365.
52. Henriksen, A. King, T. P. Mirza, O. Monsalve, R. I. Meno, K. Ipsen, H. Larsen, J. N. Gajhede, M. Spangfort, M. D. Major venom allergen of yellow jackets, Ves v 5: structural characterization of a pathogenesis-related protein superfamily. Proteins, 2001, 4(4), 438-448. (Pubitemid 33108078)
53. King, T. P. Kochoumian, L. Lam, T. Immunochemical observations of antigen 5, a major venom allergen of hornets, yellowjackets and wasps. Mol. Immunol., 1987, 24(8), 857-864. (Pubitemid 17095911)
54. Fang, K. S. Vitale, M. Fehlner, P. King, T. P. cDNA cloning and primary structure of a white-face hornet venom allergen, antigen 5. Proc. Natl. Acad. Sci. USA, 1988, 85(3), 895-899. (Pubitemid 18073934)
55. Lu, G. Villalba, M. Coscia, M. R. Hoffman, D. R. King, T. P. Sequence analysis and antigenic cross-reactivity of a venom allergen, antigen 5, from hornets, wasps, and yellow jackets. J. Immunol., 1993, 50(7), 2823-2830. (Pubitemid 23127532)
56. Tomalski, M. D. King, T. P. Miller, L. K. Expression of hornet genes encoding venom allergen antigen 5 in insects. Arch. Insect. Biochem. Physiol., 1993, 22 (3-4), 303-313.
57. Reisman, R. E. Dvorin, D. J. Randolph, C. C. Georgitis, J. W. Stinging insect allergy: natural history and modification with venom immunotherapy. J. Allergy Clin. Immunol., 1985, 75(6), 735-740.
58. King, T. P. Joslyn, A. Kochoumian, L. Antigenic cross-reactivity of venom proteins from hornets, wasps, and yellow jackets. J. Allergy Clin. Immunol., 1985, 75(5), 621-628. (Pubitemid 15056725)
59. Kasahara, M. Gutknecht, J. Brew, K. Spurr, N. Goodfellow, P. N. Cloning and mapping of a testis-specific gene with sequence similarity to a sperm-coating glycoprotein gene. Genomics, 1989, 5(3), 527-534.
60. Murphy E. V. Zhang Y. Zhu W. Biggs J. The human glioma pathogenesis-related protein is structurally related to plant pathogenesis-related proteins and its gene is expressed specifically in brain tumors. Gene, 1995, 159(1), 131-135.
61. Hawdon, J. M. Jones, B. F. Hoffman, D. R. Hotez, P. J. Cloning and characterization of Ancylostoma-secreted protein. A novel protein associated with the transition to parasitism by infective hookworm larvae. J. Biol. Chem., 1996, 271(12), 6672-6678. (Pubitemid 26104096)
62. Morissette, J. Côté, G. Anctil, J. L. Plante, M. Amyot, M. Héon, E. Trope, G. E. Weissenbach, J. Raymond, V. A common gene for juvenile and adult-onset primary open-angle glaucomas confined on chromosome 1q. Am. J. Hum. Genet., 1995, 56(6), 1431-1442.
63. Lu, G. Kochoumian, L. King, T. P. Sequence identity and antigenic cross-reactivity of white face hornet venom allergen, also a hyaluronidase, with other proteins. J. Biol. Chem., 1995, 270(9), 4457-4465.
64. Kolarich, D. Léonard, R. Hemmer, W. Altmann, F. The N-glycans of yellow jacket venom hyaluronidases and the protein sequence of its major isoform in Vespula vulgaris. FEBS J., 2005, 272(20), 5182-5190. (Pubitemid 41503149)
65. Henrissat, B. Bairoch, A. Updating the sequence-based classification of glycosyl hydrolases. Biochem. J., 1996, 316 (Pt 2), 695-696. (Pubitemid 26182174)
66. King, T. P. Lu, G. Gonzalez, M. Qian, N. Soldatova, L. Yellow jacket venom allergens, hyaluronidase and phospholipase: sequence similarity and antigenic cross-reactivity with their hornet and wasp homologs and possible implications for clinical allergy. J. Allergy Clin. Immunol., 1996, 98(3), 588-600. (Pubitemid 26377925)
67. Soldatova, L. N. Crameri, R. Gmachl, M. Kemeny, D. M. Schmidt, M. Weber, M. Mueller, U. R. Superior biologic activity of the recombinant bee venom allergen hyaluronidase expressed in baculovirus-infected insect cells as compared with Escherichia coli. J. Allergy Clin. Immunol., 1998, 101(5), 691-698. (Pubitemid 28228315)
68. Wypych, J. I. Abeyounis, C. J. Reisman, R. E. Analysis of differing patterns of cross-reactivity of honeybee and yellow jacket venomspecific IgE: use of purified venom fractions. Int. Arch. Allergy Appl. Immunol., 1989, 89(1), 60-66.
69. Hemmer, W. Focke, M. Kolarich, D. Dalik, I. Gotz, M. Jarisch, R. Identification by immunoblot of venom glycoproteins displaying immunoglobulin E-binding N-glycans as cross-reactive allergens in honeybee and yellow jacket venom. Clin. Exp. Allergy, 2004, 34(3), 460-469. (Pubitemid 38373011)
70. King, T. P. Valentine, M. D. Allergens of hymenopteran venoms. Clin. Rev. Allergy, 1987, 5(2), 137-148.
71. Abe, T. Sugita, M. Fujikura, T. Hiyoshi, J. Akasu, M. Giant hornet (Vespa mandarinia) venomous phospholipases. The purification, characterization and inhibitory properties by biscoclaurine alkaloids. Toxicon, 2000, 38(12), 1803-1816. (Pubitemid 30349130)
72. Kini, R. M. Phospholipase A2 - a complex multifunctional protein puzzle. In Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism. Kini, R. M.; Ed.; John Wiley and Sons Ltda, London, England, 1997, pp. 1-28.
73. Mustafa, F. B. Ng, F. S. P. Nguyen, T. H. Lim, L. H. K. Honeybee venom secretory phospholipase A2 induces leukotriene production but not histamine release from human basophils. Clin. Exp. Immunol., 2007, 151(1), 94-100.
74. Santos, L. D. Santos, K. S. de Souza, B. M. Arcuri, H. A. Cunha-Neto, E. Castro, F. M. Kalil, J. E. Palma, M. S. Purification, sequencing and structural characterization of the phospholipase A1 from the venom of the social wasp Polybia paulista (Hymenoptera, Vespidae). Toxicon, 2007, 450(7), 923-937.
75. Dotimas, E. M. Hamid, K. R. Hider, R. C. Ragnarsson, U. Isolation and structure analysis of bee venom mast cell degranulating peptide. Biochim Biophys Acta, 1987, 911(3), 285-293.
76. Kuchler, K. Gmachl, M. Sippl, M. J. Kreil, G. Analysis of the cDNA for phospholipase A2 from honeybee venom glands. The deduced amino acid sequence reveals homology to the corresponding vertebrate enzymes. Eur. J. Biochem., 1989, 184, 249.
77. Müller, U. R. Dudler, T. Schneider, T. Crameri, R. Fischer, H. Skrbic, D. Maibach, R. Blaser, K. Suter, M. Type I skin reactivity to native and recombinant phospholipase A2 from honeybee venom is similar. J. Allergy Clin. Immunol., 1995, 96(1), 249-254.
78. de Oliveira, M. R.; Palma, M. S. Polybitoxins: a group of phospholipases A2 from the venom of the neotropical social wasp paulistinha (Polybia paulista). Toxicon, 1998, 36(1), 189-199.
79. Costa, H. Palma, M. S. Agelotoxin: a phospholipase A (2) from the venom of the neotropical social wasp cassununga (Agelaia pallipes pallipes) (Hymenoptera-Vespidae). Toxicon, 2000, 38(10), 1367-1379. (Pubitemid 30176107)
80. Argiolas, A. Pisano, J. J. Facilitation of phospholipase A2 activity by mastoparans, a new class of mast cell degranulating peptides from wasp venom. J. Biol. Chem., 1983, 258(22), 13697-13702. (Pubitemid 14212010)
81. King, T. P. Alagon, A. C. Kuan, J. Sobotka, A. F. Lichtenstein, L. M. Immunochemical studies of yellowjacket venom proteins. Mol. Immunol., 1983, 20(3), 297-308. (Pubitemid 13160638)
82. King, T. P. Kochoumian, L. Joslyn, A. Wasp venom proteins: phospholipase A1 and B. Arch. Biochem. Biophys., 1984, 230(1), 1-12.
83. King T. P. Jim S. Y. Wittkowski K. M. Inflammatory role of two venom components of yellow jackets (Vespula vulgaris): a mast cell degranulating peptide mastoparan and phospholipase A1. Int. Arch. Allergy Immunol., 2003, 131(1), 25-32.
84. Hoffman, D. Sakell, R. Schmidt, M. Solil, the phospholipase allergen of imported fire ant venom. J. Allergy Clin. Immunol., 2005, 115(3), 611-616. (Pubitemid 40341718)
85. Hoffman, D. R. Allergens in Hymenoptera venom. XVI: Studies of the structures and cross-reactivities of vespid venom phospholipases. J. Allergy Clin. Immunol., 1986, 78(2), 337-343.
86. Sanchez, F. Blanca, M. Miranda, A. Carmona, M. J. Garcia, J. Fernandez, J. Torres, M. J. Rondon, M. C. Juarez, C. Comparison of Vespula germanica venoms obtained from different sources. Int. Arch. Allergy Immunol., 1994, 404(4), 385-389. (Pubitemid 24224642)
87. Soldatova, L. Kochoumian, L. King, T. P. Sequence similarity of a hornet (D. maculata) venom allergen phospholipase A1 with mammalian lipases. FEBS Lett., 1993, 320(2), 145-149. (Pubitemid 23098497)
88. Moawad, T. I. Hoffman, D. R. Zalat, S. Isolation, cloning and characterization of Polistes dominulus venom phospholipase A1 and its isoforms. Acta. Biol. Hung., 2005, 56 (3-4), 261-274. (Pubitemid 41238272)
89. Yang, H. Xu, X. Ma, D. Zhang, K. Lai, R. A phospholipase A1 platelet activator from the wasp venom of Vespa magnifica (Smith). Toxicon, 2008, 51(2), 289-296.
90. Mendes, M. A. de Souza, B. M. Marques, M. R. Palma, M. S. Structural and biological characterization of two novel peptides from the venom of the neotropical social wasp Agelaia pallipes pallipes. Toxicon., 2004, 44(1), 67-74. (Pubitemid 38844244)
91. Higashijima, T. Inubushi, T. Ueno, T. Miyazawa, T. NMR saturation transfer and line shape analyses of cyclic tetradepsipeptide AM toxin II: conformational equilibrium with very unequal populations. FEBS Lett., 1979, 105(2), 337-340. (Pubitemid 10237623)
92. Hancock, R. E. Chapple, D. S. Peptide antibiotics. Antimicrob. Agents Chemother., 1999, 43(6), 1317-1323.
93. Kamysz, W. Okrój, M. Łukasiak, J. Novel properties of antimicrobial peptides. Acta Biochim. Pol, 2003, 150(2), 461-469. (Pubitemid 37034698)
94. Cerovský, V. Slaninová, J. Fucík, V. Hulacová, H. Borovicková, L. Jezek, R. Bednárová, L. New potent antimicrobial peptides from the venom of Polistinae wasps and their analogs. Peptides, 2008, 29(6), 992-1003.
95. Hancock, R. E. Falla, T. Brown, M. Cationic bactericidal peptides. Adv. Microb. Physiol, 1995, 37, 135-175.
96. Wu, M. Hancock, R. E. Interaction of the cyclic antimicrobial cationic peptide bactenecin with the outer and cytoplasmic membrane. J. Biol. Chem., 1999, 274(1), 29-35. (Pubitemid 29035025)
97. Nakajima, T. Uzu, S. Wakamatsu, K. Saito, K. Miyazawa, T. Yasuhara, T. Tsukamoto, Y. Fujino, M. Amphiphilic peptides in wasp venom. Biopolymers, 1986, 25 (Suppl), S115-21.
98. Ho, C. L. Shih, Y. P. Wang, K. T. Yu, H. M. Enhancing the hypotensive effect and diminishing the cytolytic activity of hornet mastoparan B by D-amino acid substitution. Toxicon, 2001, 39(10), 1561-1566.
99. Argiolas, A. Pisano, J. J. Isolation and characterization of two new peptides, mastoparan C and crabrolin, from the venom of the European hornet, Vespa crabro. J. Biol Chem., 1984, 259(16), 10106-10111. (Pubitemid 14067684)
100. Argiolas, A. Pisano, J. J. Bombolitins, a new class of mast cell degranulating peptides from the venom of the bumblebee Megabombus pennsylvanicus. J. Biol. Chem., 1985, 260(3), 1437-1444. (Pubitemid 15144157)
101. Hirai, Y. Kuwada, M. Yasuhara, T. Yoshida, H. Nakajima, T. A new mast cell degranulating peptide homologous to mastoparan in the venom of Japanese hornet (Vespa xanthoptera). Chem. Pharm. Bull (Tokyo), 1979, 27(8), 1945-1946. (Pubitemid 10223844)
102. Hirai, Y. Yasuhara, T. Yoshida, H. Nakajima, T. Fujino, M. Kitada, C. A new mast cell degranulating peptide "mastoparan" in the venom of Vespula lewisii. Chem. Pharm. Bull (Tokyo), 1979, 27(8), 1942-1944. (Pubitemid 10223843)
103. Ho, C. L. Hwang, L. L. Structure and biological activities of a new mastoparan isolated from the venom of the hornet Vespa basalis. Biochem. J., 1991, 274 (Pt 2), 453-456.
104. Konno, K. Hisada, M. Naoki, H. Itagaki, Y. Kawai, N. Miwa, A. Yasuhara, T. Morimoto, Y. Nakata, Y. Structure and biological activities of eumenine mastoparan-AF (EMP-AF), a new mast cell degranulating peptide in the venom of the solitary wasp (Anterhynchium flavomarginatum micado). Toxicon, 2000, 38(11), 1505-1515. (Pubitemid 30206996)
105. Konno, K. Hisada, M. Fontana, R. Lorenzi, C. C. Naoki, H. Itagaki, Y. Miwa, A. Kawai, N. Nakata, Y. Yasuhara, T. Ruggiero Neto, J. de Azevedo, W. F. Jr, Palma, M. S. Nakajima, T. Anoplin, a novel antimicrobial peptide from the venom of the solitary wasp Anoplius samariensis. Biochim. Biophys. Acta, 2001, 1550(1), 70-80. (Pubitemid 33153066)
106. Ribeiro, S. P. Mendes, M. A. Dos Santos, L. D. de Souza, B. M. Marques, M. R. de Azevedo, W. F. Jr. Palma, M. S. Structural and functional characterization of N-terminally blocked peptides isolated from the venom of the social wasp Polybia paulista. Peptides, 2004, 25(12), 2069-2078. (Pubitemid 39574447)
107. Souza, B. M. Mendes, M. A. Santos, L. D. Marques, M. R. César, L. M. Almeida, R. N. Pagnocca, F. C. Konno, K. Palma, M. S. Structural and functional characterization of two novel peptide toxins isolated from the venom of the social wasp Polybia paulista. Peptides, 2005, 26(11), 2157-2164. (Pubitemid 41584079)
108. Mendes, M. A. de Souza, B. M. Palma, M. S. Structural and biological characterization of three novel mastoparan peptides from the venom of the neotropical social wasp Protopolybia exigua (Saussure). Toxicon, 2005, 45(1), 101-106.
109. Murata, K. Shinada, T. Ohfune, Y. Hisada, M. Yasuda, A. Naoki, H. Nakajima, T. Novel biologically active peptides from the venom of Polistes rothneyi iwatai. Biol. Pharm. Bull, 2006, 29(12), 2493-2497. (Pubitemid 44885875)
110. Konno, K. Hisada, M. Naoki, H. Itagaki, Y. Fontana, R. Rangel, M. Oliveira, J. S. Cabrera, M. P. Neto, J. R. Hide, I. Nakata, Y. Yasuhara, T. Nakajima, T. Eumenitin, a novel antimicrobial peptide from the venom of the solitary eumenine wasp Eumenes rubronotatus. Peptides, 2006, 27(11), 2624-2631. (Pubitemid 44584380)
111. Cerovský, V. Pohl, J. Yang, Z. Alam, N. Attygalle, A. B. Identification of three novel peptides isolated from the venom of the neotropical social wasp Polistes major major. J. Pept. Sci., 2007, 13(7), 445-450. (Pubitemid 47082894)
112. Delatorre, P. Olivieri, J. R. Ruggiero, N. J. Lorenzi, C. C. Canduri, F. Fadel, V. Konno, K. Palma, M. S. Yamane, T. de Azevedo, W. F. Jr. Preliminary cryocrystallography analysis of an eumenine mastoparan toxin isolated from the venom of the wasp Anterhynchium flavomarginatum micado. Biochim. Biophys. Acta, 2001, 1545 (1-2), 372-376. (Pubitemid 32124837)
113. Xu, X. Li, J. Lu, Q. Yang, H. Zhang, Y. Lai, R. Two families of antimicrobial peptides from wasp (Vespa magnifica) venom. Toxicon, 2006, 47(2), 249-253. (Pubitemid 43143233)
114. Malencik, D. A. Anderson, S. R. High affinity binding of the mastoparans by calmodulin. Biochem. Biophys. Res. Commun., 1983, 114(1), 50-56.
115. Okano, Y. Takagi, H. Tohmatsu, T. Nakashima, S. Kuroda, Y. Saito, K. Nozawa, Y. A wasp venom mastoparan-induced polyphosphoinositide breakdown in rat peritoneal mast cells. FEBS Lett, 1985, 188(2), 363-366. (Pubitemid 16249760)
116. Higashijima, T. Uzu, S. Nakajima, T. Ross, E. M. Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). J. Biol. Chem., 1988, 263(14), 6491-6494. (Pubitemid 18150028)
117. Higashijima, T. Burnier, J. Ross, E. M. Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity. J. Biol Chem., 1990, 265(24), 14176-14186. (Pubitemid 20281788)
118. Perianin, A. Snyderman, R. Mastoparan, a wasp venom peptide, identifies two discrete mechanisms for elevating cytosolic calcium and inositol trisphosphates in human polymorphonuclear leukocytes. J. Immunol, 1989, 143(5), 1669-1673. (Pubitemid 19217435)
119. Song D. L. Chang G. D. Ho C. L. Chang C. H. Structural requirements of mastoparan for activation of membrane-bound guanylate cyclase. Eur. J. Pharmacol, 1993, 247(3), 283-288. (Pubitemid 2012346)
120. Nakahata, N. Abe, M. T. Matsuoka, I. Nakanishi, H. Mastoparan inhibits phosphoinositide hydrolysis via pertussis toxin-insensitive G-protein in human astrocytoma cells. FEBS Lett, 1990, 260(1), 91-94. (Pubitemid 20029437)
121. Mizuno, K. Nakahata, N. Ohizumi, Y. Mastoparan-induced phosphatidylcholine hydrolysis by phospholipase D activation in human astrocytoma cells. Br. J. Pharmacol, 1995, 116(3), 2090-2096.
122. Todokoro, Y. Yumen, I. Fukushima, K. Kang, S. W. Park, J. S. Kohno, T. Wakamatsu, K. Akutsu, H. Fujiwara, T. Structure of tightly membrane-bound mastoparan-X, a G-protein-activating peptide, determined by solid-state NMR. Biophys. J., 2006, 91(4), 1368-1379. (Pubitemid 44174253)
123. Ozaki, Y. Matsumoto, Y. Yatomi, Y. Higashihara, M. Kariya, T. Kume, S. Mastoparan, a wasp venom, activates platelets via pertussis toxin-sensitive GTP-binding proteins. Biochem. Biophys. Res. Commun., 1990, 170(2), 779-785. (Pubitemid 20249487)
124. Yokokawa, N. Komatsu, M. Takeda, T. Aizawa, T. Yamada, T. Mastoparan, a wasp venom, stimulates insulin release by pancreatic islets through pertussis toxin sensitive GTP-binding protein. Biochem. Biophys. Res. Commun., 1989, 158(3), 712-716. (Pubitemid 19075981)
125. Li M. L. Liao R. W. Qiu J. W. Wang Z. J., Wu T. M. Antimicrobial activity of synthetic all-D mastoparan M. Int. J. Antimicrob. Agents, 2000, 13(3), 203-208.
126. Nakajima, T. Wakamatsu, K. Mukai, H. Mastoparan as a G Protein Activator. In Animal Toxins Rochat H, Martin-Eauclaire MF, Editors, Basel, Switzerland: Birkhäuser Verlag, 2000, p. p. 116-126.
127. Hirata, Y. Nakahata, N. Ohizumi, Y. Identification of a 97-kDa mastoparan-binding protein involving in Ca (2+) release from skeletal muscle sarcoplasmic reticulum. Mol Pharmacol, 2000, 57(6), 1235-1242. (Pubitemid 30354396)
128. Hirata, Y. Atsumi, M. Ohizumi, Y. Nakahata, N. Mastoparan binds to glycogen phosphorylase to regulate sarcoplasmic reticular Ca2+ release in skeletal muscle. Biochem. J., 2003, 371 (Pt 1), 81-88. (Pubitemid 36458081)
129. Pfeiffer, D. R. Gudz, T. I. Novgorodov, S. A. Erdahl, W. L. The peptide mastoparan is a potent facilitator of the mitochondrial permeability transition. J. Biol. Chem., 1995, 270(9), 4923-4932.
130. Rocha, T. de Souza, B. M. Palma, M. S. da Cruz-Höfling, M. A. Myotoxic effects of mastoparan from Polybia paulista (Hymenoptera, Epiponini) wasp venom in mice skeletal muscle. Toxicon, 2007, 50(5), 589-599. (Pubitemid 47404624)
131. Wang, K. R. Zhang, B. Z. Zhang, W. Yan, J. X. Li, J. Wang, R. Antitumor effects, cell selectivity and structure-activity relationship of a novel antimicrobial peptide polybia-MPI. Peptides, 2008, 29(6), 963-968.
132. Eisenbrandt, D. L. Allen, S. L. Berry, P. H. Classen, W. Bury, D. Mellert, W. Millischer, R. J. Schuh, W. Bontinck, W. J. Evaluation of the neurotoxic potential of chemicals in animals. Food Chem. Toxicol., 1994, 32(7), 655-669. (Pubitemid 24248002)
133. McCormick, K. D. Meinwald, J. Neurotoxic acylpolyamines from spider venoms J. Chem. Ecol., 1993, 19(10), 2411-2451. (Pubitemid 2000904)
134. Piek, T. Neurotoxic kinins from wasp and ant venoms. Toxicon, 1991, 29(2), 139-149.
135. Beleboni, R. O. Carolino, R. O. Pizzo, A. B. Castellan-Baldan, L. Coutinho-Netto, J. dos Santos, W. F. Coimbra, N. C. Pharmacological and biochemical aspects of GABAergic neurotransmission: pathological and neuropsychobiological relationships. Cell. Mol. Neurobiol., 2004, 24(6), 707-728. (Pubitemid 40174223)
136. Quistad, G. B. Reuter, C. C. Skinner, W. S. Dennis, P. A. Suwanrumpha, S. Fu, E. W. Paralytic and insecticidal toxins from the funnel web spider, Hololena curta. Toxicon, 1991, 29(3), 329-336.
137. Bloomquist, J. R. Kinne, L. P. Deutsch, V. Simpson, S. F. Mode of action of an insecticidal peptide toxin from the venom of a weaving spider (Diguetia canities). Toxicon, 1996, 34(9), 1072-1075. (Pubitemid 26320020)
138. Harvey, A. L. Bradley, K. N. Cochran, S. A. Rowan, E. G. Pratt, J. A. Quillfeldt, J. A. Jerusalinsky, D. A. What can toxins tell us for drug discovery? Toxicon, 1998, 36(11), 1635-1640. (Pubitemid 28511078)
139. Heading, C. E. Conus peptides and neuroprotection. Curr. Opin. Investig. Drugs, 2002, 3(6), 915-920.
140. Piek, T. Spanjer, W. Chemistry and pharmacology of solitary wasp venoms. In Venoms of the Hymenoptera. T. Piek Ed.; Academic Press, London, 1986, pp. 161-307.
141. Piek, T. Mantel, P. Van Ginkel, C. J. Megascoliakinin, a bradykinin-like compound in the venom of Megascolia flavifrons Fab. (Hymenoptera: Scoliidae). Comp. Biochem. Physiol. C, 1984, 78(2), 473-474. (Pubitemid 14095946)
142. Piek, T. Hue, B. Mony, L. Nakajima, T. Pelhate, M. Yasuhara, T. Block of synaptic transmission in insect CNS by toxins from the venom of the wasp Megascolia flavifrons (Fab.). Comp. Biochem. Physiol. C, 1987, 87(2), 287-295. (Pubitemid 17105629)
143. Yasuhara, T. Mantel, P. Nakajima, T. Piek, T. Two kinins isolated from an extract of the venom reservoirs of the solitary wasp Megascolia flavifrons. Toxicon, 1987, 25(5), 527-535. (Pubitemid 17111093)
144. Piek, T. Hue, B. Mantel, P. Nakajima, T. Pelhate, M. Yasuhara, T. Threonine6-bradykinin in the venom of the wasp Colpa interrupta (F.) presynaptically blocks nicotinic synaptic transmission in the insect CNS. Comp. Biochem. Physiol. C, 1990, 96(1), 157-162. (Pubitemid 20289562)
145. Piek, T. Duval, A. Hue, B. Karst, H. Lapied, B. Mantel, P. Nakajima, T. Pelhate, M. Schmidt, J. O. Poneratoxin, a novel peptide neurotoxin from the venom of the ant, Paraponera clavata. Comp. Biochem. Physiol. C, 1991, 99(3), 487-495.
146. Konno, K. Miwa, A. Takayama, H. Hisada, M. Itagaki, Y. Naoki, H. Yasuhara, T. Kawai, N. Alpha-pompilidotoxin (alpha-PMTX), a novel neurotoxin from the venom of a solitary wasp, facilitates transmission in the crustacean neuromuscular synapse. Neurosci. Lett., 1997, 238(3), 99-102. (Pubitemid 28034332)
147. Konno, K. Hisada, M. Itagaki, Y. Naoki, H. Kawai, N. Miwa, A. Yasuhara, T. Takayama, H. Isolation and structure of pompilidotoxins, novel peptide neurotoxins in solitary wasp venoms. Biochem. Biophys. Res. Commun., 1998, 250(3), 612-616. (Pubitemid 28484776)
148. Konno, K. Hisada, M. Naoki, H. Itagaki, Y. Yasuhara, T. Juliano, M. A. Juliano, L. Palma, M. S. Yamane, T. Nakajima, T. Isolation and sequence determination of peptides in the venom of the spider wasp (Cyphononyx dorsalis) guided by matrix-assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry. Toxicon, 2001, 39(8), 1257-1260. (Pubitemid 32295896)
149. Eldefrawi, A. T. Eldefrawi, M. E. Konno, K. Mansour, N. A. Nakanishi, K. Oltz, E. Usherwood, P. N. Structure and synthesis of a potent glutamate receptor antagonist in wasp venom. Proc. Natl. Acad. Sci. USA, 1988, 85(13), 4910-4913.
150. Piek, T. Delta-Philanthotoxin, a semi-irreversible blocker of ionchannels. Comp. Biochem. Physiol. C, 1982, 72(2), 311-315.
151. Sahara, Y. Gotoh, M. Konno, K. Miwa, A. Tsubokawa, H. Robinson, H. P. Kawai, N. A new class of neurotoxin from wasp venom slows inactivation of sodium current. Eur. J. Neurosci., 2000, 12(6), 1961-1970. (Pubitemid 30348835)
152. Miyawaki, T. Tsubokawa, H. Yokota, H. Oguro, K. Konno, K. Masuzawa, T. Kawai, N. Differential effects of novel wasp toxin on rat hippocampal interneurons. Neurosci. Lett., 2002, 328(1), 25-28. (Pubitemid 34786035)
153. Bruce, M. Bukownik, R. Eldefrawi, A. T. Eldefrawi, M. E. Goodnow, R. Jr. Kallimopoulos, T. Konno, K. Nakanishi, K. Niwa, M. Usherwood, P. N. Structure-activity relationships of analogues of the wasp toxin philanthotoxin: non-competitive antagonists of quisqualate receptors. Toxicon, 1990, 28(11), 1333-1346. (Pubitemid 20376608)
154. Piek, T. Hue, B. Lind, A. Mantel, P. van Marle, J. Visser, J. H. The venom of Ampulex compressa effects on behaviour and synaptic transmission of cockroaches. Comp. Biochem. Physiol. C, 1989, 92(2), 175-183. (Pubitemid 19090958)
155. Abe, T. Kawai, N. Niwa, A. Purification and properties of a presynaptically acting neurotoxin, mandaratoxin, from hornet (Vespa mandarinia). Biochemistry, 1982, 21(7), 1693-1697.
156. Tuǐchibaev, M. U. Tashmukhamedov, B. A. Gotgil'f, I. G. Mazannik, L. G. Orientotoxin a new presynaptic neurotoxin from the venom of the giant hornet Vespa orientalis. Bioorg. Khim., 1984, 10(3), 318-322.
157. de Oliveira, L. Cunha, A. O. Mortari, M. R. Pizzo, A. B. Miranda, A. Coimbra, N. C. dos Santos, W. F. Effects of microinjections of neurotoxin AvTx8, isolated from the social wasp Agelaia vicina (Hymenoptera, Vespidae) venom, on GABAergic nigrotectal pathways. Brain Res., 2005, 1031(1), 74-81.
158. Mendes, M. A. Palma, M. S. Two new bradykinin-related peptides from the venom of the social wasp Protopolybia exigua (Saussure). Peptides, 2006, 27(11), 2632-2639.
159. Mortari, M. R. Cunha, A. O. Carolino, R. O. Coutinho-Netto, J. Tomaz, J. C. Lopes, N. P. Coimbra, N. C. Dos Santos, W. F. Inhibition of acute nociceptive responses in rats after i.c. v. injection of Thr6-bradykinin, isolated from the venom of the social wasp, Polybia occidentalis. Br. J. Pharmacol, 2007, 151(6), 860-869. (Pubitemid 47075316)
160. Kolarich, D. Léonard, R. Hemmer, W. Altmann, F. The N-glycans of yellow jacket venom hyaluronidases and the protein sequence of its major isoform in Vespula vulgaris. FEBS J., 2005, 272(20), 5182-5190. (Pubitemid 41503149)
161. Kolarich, D. Loos, A. Léonard, R. Mach, L. Marzban, G. Hemmer, W. Altmann, F. A proteomic study of the major allergens from yellow jacket venoms. Proteomics, 2007, 7(10), 1615-1623. (Pubitemid 46841823)
162. Skov, L. K. Seppälá, U. Coen, J. J. Crickmore, N. King, T. P. Monsalve, R. Kastrup, J. S. Spangfort, M. D. Gajhede, M. Structure of recombinant Ves v 2 at 2.0 Angstrom resolution: structural analysis of an allergenic hyaluronidase from wasp venom. Acta Crystallogr. D Biol. Crystallogr., 2006, 62 (Pt 6), 595-604. (Pubitemid 43806637)
163. Tan, N. H. Ponnudurai, G. Comparative study of the enzymatic, hemorrhagic, procoagulant and anticoagulant activities of some animal venoms. Comp. Biochem. Physiol. C, 1992, 103(2), 299-302.
164. Stern, R. Devising a pathway for hyaluronan catabolism: are we there yet? Glycobiology, 2003, 13(12), 105R-115R. (Pubitemid 37508893)
165. Sunnergren, K. P. Fairman, R. P. de Blois, G. G. Glauser, F. L. Effects of protamine, heparinase, and hyaluronidase on endothelial permeability and surface charge. J. Appl. Physiol, 1987, 63(5), 1987-1992.
166. Barker, S. A. Mitchell, A. W. Walton, K. W. Weston, P. D. Separation and isolation of the hyaluronidase and phospholipase components of bee-venom and investigation of bee-venom-human serum interactions. Clin. Chim. Acta, 1966, 13(5), 582-596.
167. Son, D. J. Lee, J. W. Lee, Y. H. Song, H. S. Lee, C. K. Hong, J. T. Therapeutic application of anti-arthritis, pain-releasing, and anticancer effects of bee venom and its constituent compounds. Pharmacol. Ther., 2007, 115(2), 246-270.
168. Ohara-Imaizumi, M. Nakamichi, Y. Ozawa, S. Katsuta, H. Ishida, H. Nagamatsu, S. Mastoparan stimulates GABA release from MIN6 cells: relationship between SNARE proteins and mastoparan action. Biochem. Biophys. Res. Commun., 2001, 289(5), 1025-1030. (Pubitemid 34076292)
169. Eddlestone, G. T. Komatsu, M. Shen, L. Sharp, G. W. Mastoparan increases the intracellular free calcium concentration in two insulin-secreting cell lines by inhibition of ATP-sensitive potassium channels. Mol. Pharmacol., 1995, 47(4), 787-797.
170. Cunha, A. O. Mortari, M. R. Oliveira, L. Carolino, R. O. Coutinho-Netto, J. dos Santos, W. F. Anticonvulsant effects of the wasp Polybia ignobilis venom on chemically induced seizures and action on GABA and glutamate receptors. Comp. Biochem. Physiol. C Toxicol. Pharmacol., 2005, 141(1), 50-57. (Pubitemid 40961582)
171. Zalat, S. Elbana, S. Rizzoli, S. Schmidt, J. O. Mellor, I. R. Modulation of nicotinic acetylcholine and N-methyl-d-aspartate receptors by some Hymenopteran venoms. Toxicon, 2005, 46(3), 282-290. (Pubitemid 41033160)
172. Rozental, R. Scoble, G. T. Albuquerque, E. X. Idriss, M. Sherby, S. Sattelle, D. B. Nakanishi, K. Konno, K. Eldefrawi, A. T. Eldefrawi, M. E. Allosteric inhibition of nicotinic acetylcholine receptors of vertebrates and insects by philanthotoxin. J. Pharmacol. Exp. Ther., 1989, 249(1), 123-130. (Pubitemid 19115798)
173. Mortari, M. R. Cunha, A. O. Ferreira, L. B. dos Santos, W. F. Neurotoxins from invertebrates as anticonvulsants: from basic research to therapeutic application. Pharmacol. Ther., 2007, 114(2), 171-183.
174. Mortari M. R. Cunha A. O. de Oliveira L. Vieira E. B. Gelfuso E. A. Coutinho-Netto J. Ferreira dos Santos W. Anticonvulsant and behavioural effects of the denatured venom of the social wasp Polybia occidentalis (Polistinae, Vespidae). Basic Clin. Pharmacol. Toxicol., 2005, 97(5), 289-295. (Pubitemid 41608121)
175. Ragsdale, D. Gant, D. B. Anis, N. A. Eldefrawi, A. T. Eldefrawi, M. E. Konno, K. Miledi, R. Inhibition of rat brain glutamate receptors by philanthotoxin. J. Pharmacol. Exp. Ther., 1989, 251(1), 156-163. (Pubitemid 19261958)
176. Dohtsu, K. Okumura, K. Hagiwara, K. Palma, M. S. Nakajima, T. Isolation and sequence analysis of peptides from the venom of Protonectarina sylveirae (Hymenoptera-Vespidae). Nat. Toxins, 1993, 1(5), 271-276. (Pubitemid 23241948)