Patterns and concentration levels of polybrominated diphenyl ethers (PBDEs) in placental tissue of women in Denmark

Chemosphere

Volumn 76, Issue 11, 2009, Pages 1464-1469

  Frederiksen, Marie ^a,b   Thomsen, Marianne ^b   Vorkamp, Katrin ^b   Knudsen, Lisbeth E ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NATIONAL ENVIRONMENTAL RESEARCH INSTITUTE   (Denmark)

Author keywords

BDE 209; BFR; Flame retardant; Human biomonitoring; PCA

Indexed keywords

FLAME RETARDANTS; HEALTH; MIXTURES; ORGANIC POLLUTANTS; PRINCIPAL COMPONENT ANALYSIS;

BDE-209; CONCENTRATION LEVELS; ELEVATED CONCENTRATIONS; HUMAN BIOMONITORING; INTERNAL EXPOSURE; MEDIAN CONCENTRATION; POLYBROMINATED DIPHENYL ETHER (PBDES); TECHNICAL MIXTURES;

TISSUE;

POLYBROMINATED DIPHENYL ETHER;

BIOMONITORING; PBDE; PRINCIPAL COMPONENT ANALYSIS; SERUM; WOMENS HEALTH;

ADULT; AIR POLLUTION; ARTICLE; BODY MASS; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); DENMARK; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; NORMAL HUMAN; PLACENTA; TISSUE LEVEL;

DENMARK; EURASIA; EUROPE; NORTHERN EUROPE; SCANDINAVIA;

EID: 68849099856     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2009.07.017     Document Type: Article

References (50)

1. Alaee M., Arias P., Sjödin A., and Bergman A. An overview of commercially used brominated flame retardants, their applications, their use patterns in different countries/regions and possible modes of release. Environ. Int. 29 (2003) 683-689
2. Briggs, D., 2003. Making a difference: indicators to improve children's environmental health, report from the WHO. (last accessed 01.06.09).
3. BSEF, 2009. (last accessed 13.06.09).
4. Chan S.Y., Vasilopoulou E., and Kilby M.D. The role of the placenta in thyroid hormone delivery to the fetus. Nat. Clin. Pract. End. Met. 5 (2009) 45-54
5. COP4 Final, 2009. Summary of the Fourth Conference of the Parties to the Stockholm Convention on Persistent Organic Pollutants: 4-8 May 2009. Earth Negotiations Bull., 15. (last accessed 14.06.09).
6. Costa L.G., and Giordano G. Developmental neurotoxicity of polybrominated diphenyl ether (PBDE) flame retardants. Neurotoxicology 28 (2007) 1047-1067
7. Cross J.C. Placental function in development and disease. Reprod. Fertil. Dev. 18 (2005) 71-76
8. Darnerud P.O., Eriksen G.S., Jóhannesson T., Larsen P.B., and Viluksela M. Polybrominated diphenyl ethers: occurrence, dietary exposure, and toxicology. Environ. Health Perspect. 109 Suppl. 1 (2001) 49-68
9. Darras V. Endocrine disrupting polyhalogenated organic pollutants interfere with thyroid hormone signalling in the developing brain. Cerebellum 7 (2008) 26-37
10. de Wit C.A. An overview of brominated flame retardants in the environment. Chemosphere 46 (2002) 583-624
11. Frederiksen M., Vorkamp K., Thomsen M., and Knudsen L.E. Human internal and external exposure to PBDEs - a review of levels and sources. Int. J. Hyg. Environ. Health 212 (2009) 109-134
12. Gomara B., Herrero L., Ramos J.J., Mateo J.R., Fernandez M.A., Garcia J.F., and Gonzalez M.J. Distribution of polybrominated diphenyl ethers in human umbilical cord serum, paternal serum, maternal serum, placentas, and breast milk from Madrid population, Spain. Environ. Sci. Technol. 41 (2007) 6961-6968
13. Hallgren S., and Darnerud P.O. Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and chlorinated paraffins (CPs) in rats - testing interactions and mechanisms for thyroid hormone effects. Toxicology 177 (2002) 227-243
14. Hardy M.L. A comparison of the properties of the major commercial PBDPO/PBDE product to those of major PBB and PCB products. Chemosphere 46 (2002) 717-728
15. Herbstman J., Sjodin A., Patterson D.G., Apelberg B.J., Witter F.R., Halden R.U., Heidler J., Needham L.L., and Goldman L.R. Determinants of prenatal exposure to polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in an urban population. Environ. Health Perspect. 115 (2007) 1794-1800
16. Hertz-Picciotto I., Croen L.A., Hansen R., Jones C.R., van de Water J., and Pessah I.N. The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism. Environ. Health Perspect. 114 (2006) 1119-1125
17. Hites R.A. Polybrominated diphenyl ethers in the environment and in people: a meta-analysis of concentrations. Environ. Sci. Technol. 38 (2004) 945-956
18. Höskuldsson A. Prediction Methods in Science and Technology, Basic Theory vol. 1 (1996), Thor Publishing, Denmark
19. Kierkegaard A., Balk L., Tjarnlund U., de Wit C.A., and Jansson B. Dietary uptake and biological effects of decabromodiphenyl ether in rainbow trout (Oncorhynchus mykiss). Environ. Sci. Technol. 33 (1999) 1612-1617
20. Kierkegaard A., Asplund L., de Wit C.A., McLachlan M.S., Thomas G.O., Sweetman A.J., and Jones K.C. Fate of higher brominated PBDEs in lactating cows. Environ. Sci. Technol. 41 (2007) 417-423
21. La Guardia M.J., Hale R.C., and Harvey E. Detailed polybrominated diphenyl ether (PBDE) congener composition of the widely used penta-, octa-, and deca-PBDE technical flame-retardant mixtures. Environ. Sci. Technol. 40 (2006) 6247-6254
22. Law R.J., Allchin C.R., de Boer J., Covaci A., Herzke D., Lepom P., Morris S., Tronczynski J., and de Wit C.A. Levels and trends of brominated flame retardants in the European environment. Chemosphere 64 (2006) 187-208
23. Main K.M., Kiviranta H., Virtanen H.E., Sundquist E., Tuomisto J.T., Toumisto J., Vartiainen T., Skakkebæk N.E., and Toppari J. Flame retardants in placenta and breast milk and cryptorchidism in newborn boys. Environ. Health Perspect. 115 (2007) 1519-1526
24. Marchesini G.R., Meimaridou A., Haasnoot W., Meulenberg E., Albertus F., Mizuguchi M., Takeuchi M., Irth H., and Murk A.J. Biosensor discovery of thyroxine transport disrupting chemicals. Toxicol. Appl. Pharmacol. 232 (2008) 150-160
25. Mathiesen L., Rytting E., Mose T., and Knudsen L.E. Transport of benzo[a]pyrene in the dually perfused human placenta perfusion model: effect of albumin in the perfusion medium. Basic Clin. Pharmacol. Toxicol. (2009) 10.1111/j.1742-7843.2009.00431.x (Epub ahead of print)
26. Mazdai A., Dodder N.G., Abernathy M.P., Hites R.A., and Bigsby R.M. Polybrominated diphenyl ethers in maternal and fetal blood samples. Environ. Health Perspect. 111 (2003) 1249-1252
27. Meijer L., Weiss J., van Velzen M., Brouwer A., Bergman A., and Sauer P.J.J. Serum concentrations of neutral and phenolic organohalogens in pregnant women and some of their infants in The Netherlands. Environ. Sci. Technol. 42 (2008) 3428-3433
28. Morck A., Hakk H., Orn U., and Wehler E.K. Decabromodiphenyl ether in the rat: absorption, distribution, metabolism, and excretion. Drug Metab. Dispos. 31 (2003) 900-907
29. Myren M., Mose T., Mathiesen L., and Knudsen L.E. The human placenta - an alternative for studying foetal exposure. Toxicol. in Vitro 21 (2007) 1332-1340
30. Opperhulzen A., Volde E.W., Gobas F.A.P.C., Liem D.A.K., Steen J.M.D., and Hutzinger O. Relationship between bioconcentration in fish and steric factors of hydrophobic chemicals. Chemosphere 14 (1985) 1871-1896
31. Sandholm A., Emanuelsson B.-M., and Wehler E.K. Bioavailability and half-life of decabromodiphenyl ether (BDE-209) in rat. Xenobiotica 33 (2003) 1149-1158
32. Schecter A., Johnson-Welch S., Tung K.C., Harris T.R., Päpke O., and Rosen R. Polybrominated diphenyl ether (PBDE) levels in livers of U.S. human fetuses and newborns. J. Toxicol. Environ. Health, Part A 70 (2007) 1-6
33. Siddiqi M.A., Laessig R.H., and Reed K.D. Polybrominated diphenyl ethers (PBDEs): new pollutants-old diseases. Clin. Med. Res. 1 (2003) 281-290
34. Sjodin A., Carlsson H., Thuresson K., Sjolin S., Bergman A., and Ostman C. Flame retardants in indoor air at an electronics recycling plant and at other work environments. Environ. Sci. Technol. 35 (2001) 448-454
35. Sjodin A., Patterson D.G., and Bergman A. Brominated flame retardants in serum from U.S. blood donors. Environ. Sci. Technol. 35 (2001) 3830-3833
36. Sjodin A., Jones R., Focant J.F., Lapeza C., Wang R., McGahee E., Zhang Y., Turner W., Slazyk B., Needham L.L., and Patterson D.G. Retrospective time-trend study of polybrominated diphenyl ether and polybrominated and polychlorinated biphenyl levels in human serum from the United States. Environ. Health Perspect. 112 (2004) 654-658
37. Smedes F. Determination of total lipid using non-chlorinated solvents. The Analyst 124 (1999) 1711-1718
38. Stapleton H.M., Alaee M., Letcher R.J., and Baker J.E. Debromination of the flame retardant decabromodiphenyl ether by Juvenile Carp (Cyprinus carpio) following dietary exposure. Environ. Sci. Technol. 38 (2004) 112-119
39. Stapleton H.M., Brazil B., Holbrook R.D., Mitchelmore C.L., Benedict R., Konstantinov A., and Potter D. In vivo and in vitro debromination of decabromodiphenyl ether (BDE 209) by Juvenile Rainbow Trout and Common Carp. Environ. Sci. Technol. 40 (2006) 4653-4658
40. Strandman T., Koistinen J., and Vartiainen T. Polybrominated diphenyl ethers (PBDEs) in placenta and human milk. Organohal. Compd. 47 (2000) 61-64
41. Thomsen M., and Carlsen L. Evaluation of empirical versus non-empirical descriptors. SAR QSAR Environ. Res. 13 (2002) 525-540
42. Thomsen C., Liane V.H., and Becher G. Automated solid-phase extraction for the determination of polybrominated diphenyl ethers and polychlorinated biphenyls in serum - application on archived Norwegian samples from 1977 to 2003. J. Chromatogr. B 846 (2007) 252-263
43. Thuresson K., Bergman A., and Jakobsson K. Occupational exposure to commercial decabromodiphenyl ether in workers manufacturing or handling flame-retarded rubber. Environ. Sci. Technol. 39 (2005) 1980-1986
44. Vorkamp K., Christensen J.H., Glasius M., and Riget F.F. Persistent halogenated compounds in black guillemots (Cepphus grylle) from Greenland-levels, compound patterns and spatial trends. Mar. Pollut. Bull. 48 (2004) 111-121
45. Vorkamp K., Thomsen M., Falk K., Leslie H., Møller S., and Sørensen P.B. Temporal development of brominated flame retardants in peregrine Falcon (Falco peregrinus) eggs from South Greenland (1986-2003). Environ. Sci. Technol. 39 (2005) 8199
46. Vorkamp K., Frederiksen M., and Thomsen M. Polybrominated diphenyl ethers in the indoor environment - preliminary results from an exposure study in Denmark. Organohal. Compd. 70 (2008) 859-862
47. Wong M.H., Leung A.O.W., Chan J.K.Y., Xing G.H., Wu S.C., Xu Y., Chen L.X., Liang Y., and Leung C.K.M. Human body loadings of PCDD/Fs, PBDEs, and PCBs due to uncontrolled e-waste recycling. Organohal. Compd. 70 (2008) 946-949
48. Wu N., Herrmann T., Paepke O., Tickner J., Hale R., Harvey E., LaGuardia M., McClean M.D., and Webster T.F. Human exposure to PBDEs: associations of PBDE body burdens with food consumption and house dust concentrations. Environ. Sci. Technol. 41 (2007) 1584-1589
49. Zhou T., Ross D.G., DeVito M.J., and Crofton K.M. Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats. Toxicol. Sci. 61 (2001) 76-82
50. Zota A.R., Rudel R.A., Morello-Frosch R.A., and Brody J.G. Elevated house dust and serum concentrations of PBDEs in California: unintended consequences of furniture flammability standards?. Environ. Sci. Technol. 42 (2008) 8158-8164