메뉴 건너뛰기




Volumn 10, Issue 3, 2009, Pages 381-386

The use of dexmedetomidine in critically ill children

Author keywords

Anesthesia; Critical care; Dexmedetomidine; Mechanical ventilation; Pediatric; Sedation

Indexed keywords

BENZODIAZEPINE; DEXMEDETOMIDINE; OPIATE; HYPNOTIC SEDATIVE AGENT;

EID: 68849097671     PISSN: 15297535     EISSN: None     Source Type: Journal    
DOI: 10.1097/PCC.0b013e3181a3191f     Document Type: Article
Times cited : (63)

References (50)
  • 1
    • 0023903938 scopus 로고
    • Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-ad-renoceptor agonist
    • Virtanen R, Savola JM, Saano V, et al: Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-ad-renoceptor agonist. Eur J Pharmacol 1988; 150:9-14
    • (1988) Eur J Pharmacol , vol.150 , pp. 9-14
    • Virtanen, R.1    Savola, J.M.2    Saano, V.3
  • 2
    • 0025981022 scopus 로고
    • Central alpha 2-adre-noceptors are highly stereoselective for dexmedetomidine, the dextro enantiomer of medetomidine
    • Savola JM, Virtanen R: Central alpha 2-adre-noceptors are highly stereoselective for dexmedetomidine, the dextro enantiomer of medetomidine. Eur J Pharmacol 1991; 195: 193-199
    • (1991) Eur J Pharmacol , vol.195 , pp. 193-199
    • Savola, J.M.1    Virtanen, R.2
  • 3
    • 0036166695 scopus 로고    scopus 로고
    • Initial experience with dexmedetomidine in paediatric-aged patients
    • Tobias JD, Berkenbosch JW: Initial experience with dexmedetomidine in paediatric-aged patients. Paediatr Anaesth 2002; 12: 171-175
    • (2002) Paediatr Anaesth , vol.12 , pp. 171-175
    • Tobias, J.D.1    Berkenbosch, J.W.2
  • 4
    • 0037707400 scopus 로고    scopus 로고
    • Awake craniotomy with dexmedetomidine in pediatric patients
    • Ard J, Doyle W, Bekker A: Awake craniotomy with dexmedetomidine in pediatric patients. J Neurosurg Anesthesiol 2003; 15:263-266
    • (2003) J Neurosurg Anesthesiol , vol.15 , pp. 263-266
    • Ard, J.1    Doyle, W.2    Bekker, A.3
  • 5
    • 0142151427 scopus 로고    scopus 로고
    • Preliminary experience with dexmedetomidine in the treatment of cyclic vomiting syndrome
    • Khasawinah TA, Ramirez A, Berkenbosch JW, et al: Preliminary experience with dexmedetomidine in the treatment of cyclic vomiting syndrome. Am J Ther 2003; 10: 303-307
    • (2003) Am J Ther , vol.10 , pp. 303-307
    • Khasawinah, T.A.1    Ramirez, A.2    Berkenbosch, J.W.3
  • 6
    • 0642335955 scopus 로고    scopus 로고
    • Additional experience with dexmedetomidine in pediatric patients
    • Tobias JD, Berkenbosch JW, Russo P: Additional experience with dexmedetomidine in pediatric patients. South Med J 2003; 96: 871-875
    • (2003) South Med J , vol.96 , pp. 871-875
    • Tobias, J.D.1    Berkenbosch, J.W.2    Russo, P.3
  • 7
    • 11444260524 scopus 로고    scopus 로고
    • Sedation for paediatric stereotactic radiosurgery: The dexmedetomidine experience
    • Fahy CJ, Okumura M: Sedation for paediatric stereotactic radiosurgery: The dexmedetomi-dine experience. Anaesth Intensive Care 2004; 32:809-811
    • (2004) Anaesth Intensive Care , vol.32 , pp. 809-811
    • Fahy, C.J.1    Okumura, M.2
  • 8
    • 2442685706 scopus 로고    scopus 로고
    • The use of dexmedetomidine to facilitate opioid and benzodiazepine detoxification in an infant
    • table of contents
    • Finkel JC, Elrefai A: The use of dexmedeto-midine to facilitate opioid and benzodiaz-epine detoxification in an infant. Anesth Analg 2004; 98:1658-1659; table of contents
    • (2004) Anesth Analg , vol.98 , pp. 1658-1659
    • Finkel, J.C.1    Elrefai, A.2
  • 9
    • 0347363666 scopus 로고    scopus 로고
    • Single dose dexmedetomidine reduces agitation after sevoflurane anesthesia in children
    • table of contents
    • Ibacache ME, Munoz HR, Brandes V, et al: Single-dose dexmedetomidine reduces agitation after sevoflurane anesthesia in children. Anesth Analg 2004; 98:60-63; table of contents
    • (2004) Anesth Analg , vol.98 , pp. 60-63
    • Ibacache, M.E.1    Munoz, H.R.2    Brandes, V.3
  • 10
    • 2442680584 scopus 로고    scopus 로고
    • Dexmedetomidine in pediatrics: Controlled studies needed [8]
    • Serlin S: Dexmedetomidine in pediatrics: Controlled studies needed. Anesth Analg 2004; 98:1814 (Pubitemid 38668947)
    • (2004) Anesthesia and Analgesia , vol.98 , Issue.6 , pp. 1814
    • Serlin, S.1
  • 11
    • 2442584848 scopus 로고    scopus 로고
    • Sedation during mechanical ventilation in infants and children: Dexmedetomidine versus midazolam
    • Tobias JD, Berkenbosch JW: Sedation during mechanical ventilation in infants and children: Dexmedetomidine versus midazolam. South Med J 2004; 97:451-455
    • (2004) South Med J , vol.97 , pp. 451-455
    • Tobias, J.D.1    Berkenbosch, J.W.2
  • 12
    • 20644454903 scopus 로고    scopus 로고
    • Dexme detomidine in the treatment of withdrawal syndromes in cardiothoracic surgery patients
    • Baddigam K, Russo P, Russo J, et al: Dexme-detomidine in the treatment of withdrawal syndromes in cardiothoracic surgery patients. J Intensive Care Med 2005; 20: 118-123
    • (2005) J Intensive Care Med , vol.20 , pp. 118-123
    • Baddigam, K.1    Russo, P.2    Russo, J.3
  • 13
    • 22144448567 scopus 로고    scopus 로고
    • Prospective evaluation of dexmedetomidine for noninvasive procedural sedation in children
    • quiz 440
    • Berkenbosch JW, Wankum PC, Tobias JD: Prospective evaluation of dexmedetomidine for noninvasive procedural sedation in children. Pediatr Crit Care Med 2005; 6:435- 439; quiz 440
    • (2005) Pediatr Crit Care Med , vol.6 , pp. 435-439
    • Berkenbosch, J.W.1    Wankum, P.C.2    Tobias, J.D.3
  • 14
    • 29544446531 scopus 로고    scopus 로고
    • Use of dexme-detomidine in a pediatric heart transplant patient
    • Chrysostomou C, Zeballos T: Use of dexme-detomidine in a pediatric heart transplant patient. Pediatr Cardiol 2005; 26:651-654
    • (2005) Pediatr Cardiol , vol.26 , pp. 651-654
    • Chrysostomou, C.1    Zeballos, T.2
  • 15
    • 24944552207 scopus 로고    scopus 로고
    • The use of dexmedetomidine to facilitate acute discontinuation of opioids after cardiac transplantation in children
    • Finkel JC, Johnson YJ, Quezado ZM: The use of dexmedetomidine to facilitate acute discontinuation of opioids after cardiac transplantation in children. Crit Care Med 2005; 33:2110-2112
    • (2005) Crit Care Med , vol.33 , pp. 2110-2112
    • Finkel, J.C.1    Johnson, Y.J.2    Quezado, Z.M.3
  • 16
    • 28044471360 scopus 로고    scopus 로고
    • Single-dose dexmedetomidine reduces agitation and provides smooth extubation after pediatric adenotonsillectomy
    • Guler G, Akin A, Tosun Z, et al: Single-dose dexmedetomidine reduces agitation and provides smooth extubation after pediatric ad-enotonsillectomy. Paediatr Anaesth 2005; 15:762-766
    • (2005) Paediatr Anaesth , vol.15 , pp. 762-766
    • Guler, G.1    Akin, A.2    Tosun, Z.3
  • 17
    • 21444437093 scopus 로고    scopus 로고
    • Prolonged infusion of dexmedetomidine for sedation following tracheal resection
    • Hammer GB, Philip BM, Schroeder AR, et al: Prolonged infusion of dexmedetomidine for sedation following tracheal resection. Paedi-atr Anaesth 2005; 15:616-620
    • (2005) Paediatr Anaesth , vol.15 , pp. 616-620
    • Hammer, G.B.1    Philip, B.M.2    Schroeder, A.R.3
  • 18
    • 25644456010 scopus 로고    scopus 로고
    • Fiberoptic intubation with dexmedetomidine in two children with spinal cord impingements
    • Jooste EH, Ohkawa S, Sun LS: Fiberoptic intubation with dexmedetomidine in two children with spinal cord impingements. Anesth Analg 2005; 101:1248
    • (2005) Anesth Analg , vol.101 , pp. 1248
    • Jooste, E.H.1    Ohkawa, S.2    Sun, L.S.3
  • 19
    • 19944386258 scopus 로고    scopus 로고
    • Sedative, haemodynamic and respiratory effects of dexmedetomidine in children undergoing magnetic resonance imaging examination: Preliminary results
    • Koroglu A, Demirbilek S, Teksan H, et al: Sedative, haemodynamic and respiratory effects of dexmedetomidine in children undergoing magnetic resonance imaging examination: Preliminary results. Br J Anaesth 2005; 94:821-824
    • (2005) Br J Anaesth , vol.94 , pp. 821-824
    • Koroglu, A.1    Demirbilek, S.2    Teksan, H.3
  • 20
    • 14944369631 scopus 로고    scopus 로고
    • Rescue sedation with dexmedetomidine for diagnostic imaging: A preliminary report
    • Nichols DP, Berkenbosch JW, Tobias JD: Rescue sedation with dexmedetomidine for diagnostic imaging: A preliminary report. Paedi-atr Anaesth 2005; 15:199-203
    • (2005) Paediatr Anaesth , vol.15 , pp. 199-203
    • Nichols, D.P.1    Berkenbosch, J.W.2    Tobias, J.D.3
  • 21
    • 14944360431 scopus 로고    scopus 로고
    • Dexmedetomidine as the primary sedative agent for brain radiation therapy in a 21-month old child
    • Shukry M, Ramadhyani U: Dexmedetomidine as the primary sedative agent for brain radi- ation therapy in a 21-month old child. Pae-diatr Anaesth 2005; 15:241-242
    • (2005) Paediatr Anaesth , vol.15 , pp. 241-242
    • Shukry, M.1    Ramadhyani, U.2
  • 22
    • 33644878464 scopus 로고    scopus 로고
    • Does dexmedetomidine prevent emergence delirium in children after sevoflurane based general anesthesia?
    • Shukry M, Clyde MC, Kalarickal PL, et al: Does dexmedetomidine prevent emergence delirium in children after sevoflurane-based general anesthesia? Paediatr Anaesth 2005; 15 :1098-1104
    • (2005) Paediatr Anaesth , vol.15 , pp. 1098-1104
    • Shukry, M.1    Clyde, M.C.2    Kalarickal, P.L.3
  • 23
    • 34147146298 scopus 로고    scopus 로고
    • The pharmacokinetics and pharmacodynamics of dexmedetomidine in infants following open heart surgery
    • Su F, Nicolson SC, Adamson PC, et al: The pharmacokinetics and pharmacodynamics of dexmedetomidine in infants following open heart surgery. Crit Care Med 2005; 33(Suppl 12):A6
    • (2005) Crit Care Med , vol.33 , Issue.SUPPL. 12
    • Su, F.1    Nicolson, S.C.2    Adamson, P.C.3
  • 24
    • 27844570845 scopus 로고    scopus 로고
    • Dexmedetomidine sedation in a pediatric cardiac patient scheduled for MRI
    • Young ET: Dexmedetomidine sedation in a pediatric cardiac patient scheduled for MRI. Can J Anaesth 2005; 52:730-732
    • (2005) Can J Anaesth , vol.52 , pp. 730-732
    • Young, E.T.1
  • 25
    • 33645553849 scopus 로고    scopus 로고
    • Use of dexmedetomidine in children after cardiac and thoracic surgery
    • Chrysostomou C, Di Filippo S, Manrique AM, et al: Use of dexmedetomidine in children after cardiac and thoracic surgery. Pediatr Crit Care Med 2006; 7:126-131
    • (2006) Pediatr Crit Care Med , vol.7 , pp. 126-131
    • Chrysostomou, C.1    Di Filippo, S.2    Manrique, A.M.3
  • 26
    • 33645325370 scopus 로고    scopus 로고
    • Use of dexmedetomidine in awake craniotomy in adolescents: Report of two cases
    • Everett LL, van Rooyen IF, Warner MH, et al: Use of dexmedetomidine in awake craniot-omy in adolescents: Report of two cases. Pae-diatr Anaesth 2006; 16:338-342
    • (2006) Paediatr Anaesth , vol.16 , pp. 338-342
    • Everett, L.L.1    Van Rooyen, I.F.2    Warner, M.H.3
  • 27
    • 33748341460 scopus 로고    scopus 로고
    • Dexmedetomidine decreases emergence agitation in pediatric patients after sevoflurane anesthesia without surgery
    • Isik B, Arslan M, Tunga AD, et al: Dexme-detomidine decreases emergence agitation in pediatric patients after sevoflurane anesthesia without surgery. Paediatr Anaesth 2006; 16:748-753
    • (2006) Paediatr Anaesth , vol.16 , pp. 748-753
    • Isik, B.1    Arslan, M.2    Tunga, A.D.3
  • 28
    • 33745820883 scopus 로고    scopus 로고
    • A comparison of the sedative, hemodynamic, and respiratory effects of dexmedetomidine and propofol in children undergoing magnetic resonance imaging
    • table of contents
    • Koroglu A, Teksan H, Sagir O, et al: A comparison of the sedative, hemodynamic, and respiratory effects of dexmedetomidine and propofol in children undergoing magnetic resonance imaging. Anesth Analg 2006; 103: 63- 67; table of contents
    • (2006) Anesth Analg , vol.103 , pp. 63-67
    • Koroglu, A.1    Teksan, H.2    Sagir, O.3
  • 29
    • 33748352311 scopus 로고    scopus 로고
    • Monitored anesthesia care with a combination of ketamine and dexmedetomidine during magnetic resonance imaging in three children with trisomy 21 and obstructive sleep apnea
    • Luscri N, Tobias JD: Monitored anesthesia care with a combination of ketamine and dexmedetomidine during magnetic resonance imaging in three children with tri-somy 21 and obstructive sleep apnea. Paedi-atr Anaesth 2006; 16:782-786
    • (2006) Paediatr Anaesth , vol.16 , pp. 782-786
    • Luscri, N.1    Tobias, J.D.2
  • 30
    • 33745833089 scopus 로고    scopus 로고
    • Dexmedetomidine for pediatric sedation for computed tomography imaging studies
    • table of contents
    • Mason KP, Zgleszewski SE, Dearden JL, et al: Dexmedetomidine for pediatric sedation for computed tomography imaging studies. Anesth Analg 2006; 103:57- 62; table of contents
    • (2006) Anesth Analg , vol.103 , pp. 57-62
    • Mason, K.P.1    Zgleszewski, S.E.2    Dearden, J.L.3
  • 31
    • 33745862411 scopus 로고    scopus 로고
    • Preliminary experience with dexmedetomidine in pediatric anesthesia
    • Mukhtar AM, Obayah EM, Hassona AM: Preliminary experience with dexmedetomidine in pediatric anesthesia. Anesth Analg 2006; 103:250
    • (2006) Anesth Analg , vol.103 , pp. 250
    • Mukhtar, A.M.1    Obayah, E.M.2    Hassona, A.M.3
  • 32
    • 33745827424 scopus 로고    scopus 로고
    • The use of dexmedetomidine in pediatric cardiac surgery
    • table of contents
    • Mukhtar AM, Obayah EM, Hassona AM: The use of dexmedetomidine in pediatric cardiac surgery. Anesth Analg 2006; 103:52-56; table of contents
    • (2006) Anesth Analg , vol.103 , pp. 52-56
    • Mukhtar, A.M.1    Obayah, E.M.2    Hassona, A.M.3
  • 33
    • 33751312459 scopus 로고    scopus 로고
    • A phase I, two center study of the pharmacokinetics and pharmacodynamics of dexmedetomidine in children
    • Petroz GC, Sikich N, James M, et al: A phase I, two-center study of the pharmacokinetics and pharmacodynamics of dexmedetomidine in children. Anesthesiology 2006; 105: 1098-1110
    • (2006) Anesthesiology , vol.105 , pp. 1098-1110
    • Petroz, G.C.1    Sikich, N.2    James, M.3
  • 34
    • 33745834806 scopus 로고    scopus 로고
    • Short duration large dose dexmedetomidine in a pediatric patient during procedural sedation
    • table of contents
    • Rosen DA, Daume JT: Short duration large dose dexmedetomidine in a pediatric patient during procedural sedation. Anesth Analg 2006; 103:68 - 69; table of contents
    • (2006) Anesth Analg , vol.103 , pp. 68-69
    • Rosen, D.A.1    Daume, J.T.2
  • 35
    • 33947209104 scopus 로고    scopus 로고
    • Dexmedetomidine to treat opioid withdrawal in infants following prolonged sedation in the pediatric ICU
    • Tobias JD: Dexmedetomidine to treat opioid withdrawal in infants following prolonged sedation in the pediatric ICU. J Opioid Manag 2006; 2:201-205
    • (2006) J Opioid Manag , vol.2 , pp. 201-205
    • Tobias, J.D.1
  • 36
    • 33746375052 scopus 로고    scopus 로고
    • Dexmedeto- midine-ketamine and propofol-ketamine combinations for anesthesia in spontaneously breathing pediatric patients undergoing cardiac catheterization
    • Tosun Z, Akin A, Guler G, et al: Dexmedeto- midine-ketamine and propofol-ketamine combinations for anesthesia in spontaneously breathing pediatric patients undergoing cardiac catheterization. J Cardiothorac Vasc Anesth 2006; 20:515-519
    • (2006) J Cardiothorac Vasc Anesth , vol.20 , pp. 515-519
    • Tosun, Z.1    Akin, A.2    Guler, G.3
  • 37
    • 33745336884 scopus 로고    scopus 로고
    • Sedation using dexmedetomidine in pediatric burn patients
    • Walker J, Maccallum M, Fischer C, et al: Sedation using dexmedetomidine in pediatric burn patients. J Burn Care Res 2006; 27:206-210
    • (2006) J Burn Care Res , vol.27 , pp. 206-210
    • Walker, J.1    MacCallum, M.2    Fischer, C.3
  • 38
    • 33847632825 scopus 로고    scopus 로고
    • Dexmedetomidine for the treatment of post-anesthesia shivering in children
    • Blaine Easley R, Brady KM, Tobias JD: Dexmedetomidine for the treatment of post-anesthesia shivering in children. Paediatr Anaesth 2007; 17:341-346
    • (2007) Paediatr Anaesth , vol.17 , pp. 341-346
    • Blaine Easley, R.1    Brady, K.M.2    Tobias, J.D.3
  • 39
    • 34247396969 scopus 로고    scopus 로고
    • Hemodynamic and respiratory changes following dexmedetomi-dine administration during general anesthesia: Sevoflurane vs desflurane
    • Deutsch E, Tobias JD: Hemodynamic and respiratory changes following dexmedetomi-dine administration during general anesthesia: Sevoflurane vs desflurane. Paediatr An-aesth 2007; 17:438-444
    • (2007) Paediatr Anaesth , vol.17 , pp. 438-444
    • Deutsch, E.1    Tobias, J.D.2
  • 40
    • 34548670030 scopus 로고    scopus 로고
    • Pharma-cokinetics of dexmedetomidine in postsurgical pediatric intensive care unit patients: Preliminary study
    • Diaz SM, Rodarte A, Foley J, et al: Pharma-cokinetics of dexmedetomidine in postsurgical pediatric intensive care unit patients: Preliminary study. Pediatr Crit Care Med 2007; 8:419-424
    • (2007) Pediatr Crit Care Med , vol.8 , pp. 419-424
    • Diaz, S.M.1    Rodarte, A.2    Foley, J.3
  • 41
    • 34547691502 scopus 로고    scopus 로고
    • Dexmedeto-midine for pediatric MRI sedation: A review of a series of cases
    • Heard CM, Joshi P, Johnson K: Dexmedeto-midine for pediatric MRI sedation: A review of a series of cases. Paediatr Anaesth 2007; 17:888-892
    • (2007) Paediatr Anaesth , vol.17 , pp. 888-892
    • Heard, C.M.1    Joshi, P.2    Johnson, K.3
  • 42
    • 34548668947 scopus 로고    scopus 로고
    • Use of dexmedetomidine in patients with trisomy 21 after cardiac surgery
    • Kalyanaraman M, Costello JL, Starr JP: Use of dexmedetomidine in patients with trisomy 21 after cardiac surgery. Pediatr Cardiol 2007; 28:396-399
    • (2007) Pediatr Cardiol , vol.28 , pp. 396-399
    • Kalyanaraman, M.1    Costello, J.L.2    Starr, J.P.3
  • 43
    • 33846130582 scopus 로고    scopus 로고
    • Initial experience with dexmedetomidine for diagnostic and interventional cardiac catheterization in children
    • Munro HM, Tirotta CF, Felix DE, et al: Initial experience with dexmedetomidine for diagnostic and interventional cardiac catheterization in children. Paediatr Anaesth 2007; 17:109-112
    • (2007) Paediatr Anaesth , vol.17 , pp. 109-112
    • Munro, H.M.1    Tirotta, C.F.2    Felix, D.E.3
  • 44
    • 34548312239 scopus 로고    scopus 로고
    • Dexme-detomidine as an analgesic for pediatric tonsillectomy and adenoidectomy
    • Olutoye O, Kim T, Giannoni C, et al: Dexme-detomidine as an analgesic for pediatric tonsillectomy and adenoidectomy. Paediatr An-aesth 2007; 17:1007-1008
    • (2007) Paediatr Anaesth , vol.17 , pp. 1007-1008
    • Olutoye, O.1    Kim, T.2    Giannoni, C.3
  • 45
    • 34250355622 scopus 로고    scopus 로고
    • Effects of preanesthetic administration of midazolam, clonidine, or dexmedetomidine on postoperative pain and anxiety in children
    • Schmidt AP, Valinetti EA, Bandeira D, et al: Effects of preanesthetic administration of midazolam, clonidine, or dexmedetomidine on postoperative pain and anxiety in children. Paediatr Anaesth 2007; 17:667-674
    • (2007) Paediatr Anaesth , vol.17 , pp. 667-674
    • Schmidt, A.P.1    Valinetti, E.A.2    Bandeira, D.3
  • 46
    • 35848963854 scopus 로고    scopus 로고
    • The use of dexmedetomidine during laryngoscopy, bronchoscopy, and tracheal extubation following tracheal reconstruction
    • Seybold JL, Ramamurthi RJ, Hammer GB: The use of dexmedetomidine during laryn-goscopy, bronchoscopy, and tracheal extuba-tion following tracheal reconstruction. Pae-diatr Anaesth 2007; 17:1212-1214
    • (2007) Paediatr Anaesth , vol.17 , pp. 1212-1214
    • Seybold, J.L.1    Ramamurthi, R.J.2    Hammer, G.B.3
  • 47
    • 0026571542 scopus 로고
    • Assessing distress in pediatric intensive care environments: The COMFORT scale
    • Ambuel B, Hamlett KW, Marx CM, et al: Assessing distress in pediatric intensive care environments: The COMFORT scale. J Pedi-atr Psychol 1992; 17:95-109
    • (1992) J Pediatr Psychol , vol.17 , pp. 95-109
    • Ambuel, B.1    Hamlett, K.W.2    Marx, C.M.3
  • 48
    • 33847392052 scopus 로고    scopus 로고
    • Dexmedetomidine: An updated review
    • Gerlach AT, Dasta JF: Dexmedetomidine: An updated review. Ann Pharmacother 2007; 41: 245-252
    • (2007) Ann Pharmacother , vol.41 , pp. 245-252
    • Gerlach, A.T.1    Dasta, J.F.2
  • 49
    • 34147136551 scopus 로고    scopus 로고
    • Dexmedetomidine: Applications in pediatric critical care and pediatric anesthesiology
    • Tobias JD: Dexmedetomidine: Applications in pediatric critical care and pediatric anesthesiology. Pediatr Crit Care Med 2007; 8:115-131
    • (2007) Pediatr Crit Care Med , vol.8 , pp. 115-131
    • Tobias, J.D.1
  • 50
    • 0037313063 scopus 로고    scopus 로고
    • The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep promoting pathway to exert its sedative effects
    • Nelson LE, Lu J, Guo T, et al: The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects. Anesthesiology 2003; 98:428-436
    • (2003) Anesthesiology , vol.98 , pp. 428-436
    • Nelson, L.E.1    Lu, J.2    Guo, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.