NOD2/CARD15 polymorphisms impair innate immunity and increase susceptibility to gastric cancer in an Italian population

Human Immunology

Volumn 70, Issue 9, 2009, Pages 729-732

  Angeletti, Silvia ^a   Galluzzo, Sara ^a   Santini, Daniele ^a   Ruzzo, Annamaria ^b   Vincenzi, Bruno ^a   Ferraro, Elisabetta ^a   Spoto, Chiara ^a   Lorino, Giulia ^c   Graziano, Nicoletta ^a   Calvieri, Alice ^a   Magnani, Mauro ^b   Graziano, Francesco ^d   Pantano, Francesco ^a   Tonini, Giuseppe ^a   Dicuonzo, Giordano ^a  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

^b UNIVERSITY OF URBINO   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d Hospital of Urbino   (Italy)

Author keywords

Cancer risk; CARD15 NOD2 polymorphisms; Gastric cancer; Genetic susceptibility; Innate immunity

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN PROTEIN;

ADULT; AGED; ARTICLE; CANCER INCIDENCE; CANCER SUSCEPTIBILITY; CASE CONTROL STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE FREQUENCY; GENE FUNCTION; GENE MUTATION; HAPLOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HUMAN CELL; INNATE IMMUNITY; ITALY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STOMACH CANCER;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IMMUNITY, INNATE; ITALY; MIDDLE AGED; NOD2 SIGNALING ADAPTOR PROTEIN; POLYMORPHISM, GENETIC; RISK FACTORS; STOMACH NEOPLASMS;

EID: 68749115003     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2009.04.026     Document Type: Article

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