Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4+ T-lymphocytes

Virology

Volumn 391, Issue 2, 2009, Pages 203-211

  Stax, Martijn J ^a   van Montfort, Thijs ^a   Sprenger, Richard R ^b   Melchers, Mark ^a   Sanders, Rogier W ^a   van Leeuwen, Elisabeth ^b   Repping, Sjoerd ^b   Pollakis, Georgios ^a   Speijer, Dave ^b   Paxton, William A ^a  

^a Center for Infection and Immunity Amsterdam CINIMA   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

DC SIGN; Dendritic cells; HIV 1; MUC6; Mucin 6

Indexed keywords

BILE SALT; CD209 ANTIGEN; CD4 ANTIGEN; MUCIN 6; TRIACYLGLYCEROL LIPASE;

ARTICLE; CD4+ T LYMPHOCYTE; CELL INTERACTION; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INHIBITION KINETICS; MASS SPECTROMETRY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PURIFICATION; SEMINAL PLASMA; SEXUAL TRANSMISSION; VIRUS TRANSMISSION; WESTERN BLOTTING;

CD4-POSITIVE T-LYMPHOCYTES; CELL ADHESION MOLECULES; CELL LINE; CELLS, CULTURED; DENDRITIC CELLS; HIV-1; HUMANS; LECTINS, C-TYPE; MUCIN-6; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SEMEN;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 68749106231     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.06.011     Document Type: Article

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