Synthesis, characterization and evaluation of thiolated quaternary ammonium-chitosan conjugates for enhanced intestinal drug permeation

European Journal of Pharmaceutical Sciences

Volumn 38, Issue 2, 2009, Pages 112-120

  Zambito, Ylenia ^a   Fogli, Stefano ^a   Zaino, Chiara ^a   Stefanelli, Fabio ^a   Breschi, Maria C ^a   Di Colo, Giacomo ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Caco 2 cell culture; Epithelial permeability enhancement; Intestinal absorption enhancement; Intestinal epithelium model; Thiolated quaternary ammonium chitosan; Thiomer

Indexed keywords

CHITOSAN; DESOXIMETASONE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; QUATERNARY AMMONIUM DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG ABSORPTION; DRUG FORMULATION; DRUG PENETRATION; DRUG TRANSPORT; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNTHESIS;

ANIMALS; CACO-2 CELLS; CHITOSAN; DEXAMETHASONE; HUMANS; INTESTINAL MUCOSA; MAGNETIC RESONANCE SPECTROSCOPY; MALE; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, WISTAR; SULFHYDRYL COMPOUNDS;

EID: 68749100591     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2009.06.006     Document Type: Article

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