메뉴 건너뛰기




Volumn 2, Issue 3, 2008, Pages 149-161

Review: Evaluating combination therapies for asthma: Pros, cons, and comparative benefits

Author keywords

asthma; combination therapy; inhaled corticosteroid; leukotriene receptor antagonist; long acting 2 agonist

Indexed keywords

ANTIASTHMATIC AGENT; BECLOMETASONE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; BUDESONIDE PLUS FORMOTEROL; BUDESONIDE PLUS TERBUTALINE; CORTICOSTEROID; FLUTICASONE PLUS MONTELUKAST; FLUTICASONE PLUS SALMETEROL; FORMOTEROL; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONTELUKAST; PLACEBO; PREDNISOLONE; PREDNISONE; SALBUTAMOL; SALMETEROL; TERBUTALINE;

EID: 68749098714     PISSN: 17534658     EISSN: None     Source Type: Journal    
DOI: 10.1177/1753465808092280     Document Type: Review
Times cited : (8)

References (64)
  • 3
    • 0142074290 scopus 로고    scopus 로고
    • Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomised, comparative trial
    • Bjermer, L., Bisgaard, H., Bousquet, J., Fabbri, L.M., Greening, A.P., Haahtela, T. et al. (2003) Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomised, comparative trial. BMJ 327: 1-6.
    • (2003) BMJ , vol.327 , pp. 1-6
    • Bjermer, L.1    Bisgaard, H.2    Bousquet, J.3    Fabbri, L.M.4    Greening, A.P.5    Haahtela, T.6
  • 4
    • 0036165978 scopus 로고    scopus 로고
    • A meta-analysis of the dose-response relationship of inhaled corticosteroids in adolescents and adults with mild to moderate persistent asthma
    • Bousquet, J., Ben-Joseph, R., Messonnier, M., Alemao, E. and Gould, A.L. (2002) A meta-analysis of the dose-response relationship of inhaled corticosteroids in adolescents and adults with mild to moderate persistent asthma. Clin Ther 24: 1-20.
    • (2002) Clin Ther , vol.24 , pp. 1-20
    • Bousquet, J.1    Ben-Joseph, R.2    Messonnier, M.3    Alemao, E.4    Gould, A.L.5
  • 5
    • 21844431891 scopus 로고    scopus 로고
    • Increased risk of asthma attacks and emergency visits among asthma patients with allergic rhinitis: a subgroup analysis of the investigation of montelukast as a partner agent for complementary therapy [corrected]
    • Bousquet, J., Gaugris, S., Kocevar, V.S., Zhang, Q., Yin, D.D., Polos, P.G. et al. (2005) Increased risk of asthma attacks and emergency visits among asthma patients with allergic rhinitis: a subgroup analysis of the investigation of montelukast as a partner agent for complementary therapy [corrected]. Clin Exp Allergy 35: 723-727.
    • (2005) Clin Exp Allergy , vol.35 , pp. 723-727
    • Bousquet, J.1    Gaugris, S.2    Kocevar, V.S.3    Zhang, Q.4    Yin, D.D.5    Polos, P.G.6
  • 7
    • 31444450081 scopus 로고    scopus 로고
    • Efficacy of montelukast during the allergy season in patients with chronic asthma and seasonal aeroallergen sensitivity
    • Busse, W.W., Casale, T.B., Dykewicz, M.S., Meltzer, E.O., Bird, S.R., Hustad, C.M. et al. (2006) Efficacy of montelukast during the allergy season in patients with chronic asthma and seasonal aeroallergen sensitivity. Ann Allergy Asthma Immunol 96: 60-68.
    • (2006) Ann Allergy Asthma Immunol , vol.96 , pp. 60-68
    • Busse, W.W.1    Casale, T.B.2    Dykewicz, M.S.3    Meltzer, E.O.4    Bird, S.R.5    Hustad, C.M.6
  • 9
    • 0031895962 scopus 로고    scopus 로고
    • Personality profiles and breathlessness perception in outpatients with different gradings of asthma
    • Chetta, A., Gerra, G., Foresi, A., Zaimovic, A., Del, D.M., Chittolini, B. et al. (1998) Personality profiles and breathlessness perception in outpatients with different gradings of asthma. Am J Respir Crit Care Med 157: 116-122.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 116-122
    • Chetta, A.1    Gerra, G.2    Foresi, A.3    Zaimovic, A.4    Del, D.M.5    Chittolini, B.6
  • 10
    • 0031042155 scopus 로고    scopus 로고
    • Allergic rhinitis and asthma: how important is the link?
    • Corren, J. (1997) Allergic rhinitis and asthma: how important is the link? J Allergy Clin Immunol 99: S781-S786.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. S781-S786
    • Corren, J.1
  • 11
    • 0038555464 scopus 로고    scopus 로고
    • Effects of montelukast on surrogate inflammatory markers in corticosteroid-treated patients with asthma
    • Currie, G.P., Lee, D.K., Haggart, K., Bates, C.E. and Lipworth, B.J. (2003) Effects of montelukast on surrogate inflammatory markers in corticosteroid-treated patients with asthma. Am J Respir Crit Care Med 167: 1232-1238.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1232-1238
    • Currie, G.P.1    Lee, D.K.2    Haggart, K.3    Bates, C.E.4    Lipworth, B.J.5
  • 12
    • 0036308418 scopus 로고    scopus 로고
    • Bronchoprotective effects of leukotriene receptor antagonists in asthma: a meta-analysis
    • Currie, G.P. and Lipworth, B.J. (2002) Bronchoprotective effects of leukotriene receptor antagonists in asthma: a meta-analysis. Chest 122: 146-150.
    • (2002) Chest , vol.122 , pp. 146-150
    • Currie, G.P.1    Lipworth, B.J.2
  • 13
    • 33746049481 scopus 로고    scopus 로고
    • CONtrol Centered Patient Treatment (CONCEPT)
    • D'Urzo, A.D. (2005) CONtrol Centered Patient Treatment (CONCEPT). Clin Ther 27: 1312-1315.
    • (2005) Clin Ther , vol.27 , pp. 1312-1315
    • D'Urzo, A.D.1
  • 14
    • 34147176795 scopus 로고    scopus 로고
    • Long-acting beta2-agonists versus anti-leukotrienes as add-on therapy to inhaled corticosteroids for chronic asthma
    • Ducharme, F.M., Lasserson, T.J. and Cates, C.J. (2006) Long-acting beta2-agonists versus anti-leukotrienes as add-on therapy to inhaled corticosteroids for chronic asthma. Cochrane Database Syst Rev: CD003137.
    • (2006) Cochrane Database Syst Rev , pp. CD003137
    • Ducharme, F.M.1    Lasserson, T.J.2    Cates, C.J.3
  • 16
    • 0031042693 scopus 로고    scopus 로고
    • Cigarette smoking stimulates cysteinyl leukotriene production in man
    • Fauler, J. and Frolich, J.C. (1997) Cigarette smoking stimulates cysteinyl leukotriene production in man. Eur J Clin Invest 27: 43-47.
    • (1997) Eur J Clin Invest , vol.27 , pp. 43-47
    • Fauler, J.1    Frolich, J.C.2
  • 17
    • 0034821077 scopus 로고    scopus 로고
    • Salmeterol powder provides significantly better benefit than montelukast in asthmatic patients receiving concomitant inhaled corticosteroid therapy
    • Fish, J.E., Israel, E., Murray, J.J., Emmett, A., Boone, R., Yancey, S.W. et al. (2001) Salmeterol powder provides significantly better benefit than montelukast in asthmatic patients receiving concomitant inhaled corticosteroid therapy. Chest 120: 423-430.
    • (2001) Chest , vol.120 , pp. 423-430
    • Fish, J.E.1    Israel, E.2    Murray, J.J.3    Emmett, A.4    Boone, R.5    Yancey, S.W.6
  • 18
    • 19544364869 scopus 로고    scopus 로고
    • The CONCEPT trial: a 1-year, multicenter, randomized,double-blind, double-dummy comparison of a stable dosing regimen of salmeterol/fluticasone propionate with an adjustable maintenance dosing regimen of formoterol/budesonide in adults with persistent asthma
    • FitzGerald, J.M., Boulet, L.P. and Follows, R.M. (2005) The CONCEPT trial: a 1-year, multicenter, randomized,double-blind, double-dummy comparison of a stable dosing regimen of salmeterol/fluticasone propionate with an adjustable maintenance dosing regimen of formoterol/budesonide in adults with persistent asthma. Clin Ther 27: 393-406.
    • (2005) Clin Ther , vol.27 , pp. 393-406
    • FitzGerald, J.M.1    Boulet, L.P.2    Follows, R.M.3
  • 19
    • 10744229972 scopus 로고    scopus 로고
    • Adjustable maintenance dosing with budesonide/ formoterol reduces asthma exacerbations compared with traditional fixed dosing: a five-month multicentre Canadian study
    • FitzGerald, J.M., Sears, M.R., Boulet, L.P., Becker, A.B., McIvor, A.R., Ernst, P. et al. (2003) Adjustable maintenance dosing with budesonide/ formoterol reduces asthma exacerbations compared with traditional fixed dosing: a five-month multicentre Canadian study. Can Respir J 10: 427-434.
    • (2003) Can Respir J , vol.10 , pp. 427-434
    • FitzGerald, J.M.1    Sears, M.R.2    Boulet, L.P.3    Becker, A.B.4    McIvor, A.R.5    Ernst, P.6
  • 21
    • 0028264310 scopus 로고
    • Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Allen & Hanburys Limited UK Study Group
    • Greening, A.P., Ind, P.W., Northfield, M. and Shaw, G. (1994) Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Allen & Hanburys Limited UK Study Group. Lancet 344: 219-224.
    • (1994) Lancet , vol.344 , pp. 219-224
    • Greening, A.P.1    Ind, P.W.2    Northfield, M.3    Shaw, G.4
  • 22
    • 10944232455 scopus 로고    scopus 로고
    • How representative are clinical study patients with asthma or COPD for a larger “real life” population of patients with obstructive lung disease?
    • Herland, K., Akselsen, J.P., Skjonsberg, O.H. and Bjermer, L. (2005) How representative are clinical study patients with asthma or COPD for a larger “real life” population of patients with obstructive lung disease? Respir Med 99: 11-19.
    • (2005) Respir Med , vol.99 , pp. 11-19
    • Herland, K.1    Akselsen, J.P.2    Skjonsberg, O.H.3    Bjermer, L.4
  • 24
    • 0033807715 scopus 로고    scopus 로고
    • Asthma drug adherence in a long term clinical trial
    • Jonasson, G., Carlsen, K.H. and Mowinckel, P. (2000) Asthma drug adherence in a long term clinical trial. Arch Dis Child 83: 330-333.
    • (2000) Arch Dis Child , vol.83 , pp. 330-333
    • Jonasson, G.1    Carlsen, K.H.2    Mowinckel, P.3
  • 25
    • 0027194120 scopus 로고
    • Airways hyperresponsiveness, bronchodilator response, allergy and smoking predict improvement in FEV1 during long-term inhaled corticosteroid treatment. Dutch CNSLD Study Group
    • Kerstjens, H.A., Overbeek, S.E., Schouten, J.P., Brand, P.L. and Postma, D.S. (1993) Airways hyperresponsiveness, bronchodilator response, allergy and smoking predict improvement in FEV1 during long-term inhaled corticosteroid treatment. Dutch CNSLD Study Group. Eur Respir J 6: 868-876.
    • (1993) Eur Respir J , vol.6 , pp. 868-876
    • Kerstjens, H.A.1    Overbeek, S.E.2    Schouten, J.P.3    Brand, P.L.4    Postma, D.S.5
  • 26
  • 28
    • 0033405946 scopus 로고    scopus 로고
    • Montelukast added to inhaled beclomethasone in treatment of asthma. Montelukast/Beclomethasone Additivity Group
    • Laviolette, M., Malmstrom, K., Lu, S., Chervinsky, P., Pujet, J.C., Peszek, I. et al. (1999) Montelukast added to inhaled beclomethasone in treatment of asthma. Montelukast/Beclomethasone Additivity Group. Am J Respir Crit Care Med 160: 1862-1868.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1862-1868
    • Laviolette, M.1    Malmstrom, K.2    Lu, S.3    Chervinsky, P.4    Pujet, J.C.5    Peszek, I.6
  • 29
    • 0035938606 scopus 로고    scopus 로고
    • Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: a randomized controlled trial
    • Lemanske, Jr R.F., Sorkness C.A
    • Lazarus, S.C., Boushey, H.A., Fahy, J.V., Chinchilli, V.M., Lemanske Jr, R.F., Sorkness, C.A. et al. (2001) Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: a randomized controlled trial. JAMA 285: 2583-2593.
    • (2001) JAMA , vol.285 , pp. 2583-2593
    • Lazarus, S.C.1    Boushey, H.A.2    Fahy, J.V.3    Chinchilli, V.M.4
  • 31
    • 18744421762 scopus 로고    scopus 로고
    • Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction
    • Leff, J.A., Busse, W.W., Pearlman, D., Bronsky, E.A., Kemp, J., Hendeles, L. et al. (1998) Montelukast, a leukotriene-receptor antagonist, for the treatment of mild asthma and exercise-induced bronchoconstriction. N Engl J Med 339: 147-152.
    • (1998) N Engl J Med , vol.339 , pp. 147-152
    • Leff, J.A.1    Busse, W.W.2    Pearlman, D.3    Bronsky, E.A.4    Kemp, J.5    Hendeles, L.6
  • 32
    • 0035041624 scopus 로고    scopus 로고
    • Fluticasone propionate/ salmeterol combination
    • Lipworth, B.J. (2001) Fluticasone propionate/ salmeterol combination. J Allergy Clin Immunol 107: 746.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 746
    • Lipworth, B.J.1
  • 33
    • 18344372554 scopus 로고    scopus 로고
    • Bronchodilator reversibility to albuterol predicts bronchodilator response to salmeterol
    • Lipworth, B.J. and Jackson, C.M. (2002) Bronchodilator reversibility to albuterol predicts bronchodilator response to salmeterol. Chest 121: 1382.
    • (2002) Chest , vol.121 , pp. 1382
    • Lipworth, B.J.1    Jackson, C.M.2
  • 34
    • 0035135829 scopus 로고    scopus 로고
    • Inhaled budesonide/formoterol combination
    • McGavin, J.K., Goa, K.L. and Jarvis, B. (2001) Inhaled budesonide/formoterol combination. Drugs 61: 71-78.
    • (2001) Drugs , vol.61 , pp. 71-78
    • McGavin, J.K.1    Goa, K.L.2    Jarvis, B.3
  • 36
    • 0034538067 scopus 로고    scopus 로고
    • Fluticasone propionate/salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast
    • Nelson, H.S., Busse, W.W., Kerwin, E., Church, N., Emmett, A., Rickard, K. et al. (2000) Fluticasone propionate/salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast. J Allergy Clin Immunol 106: 1088-1095.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 1088-1095
    • Nelson, H.S.1    Busse, W.W.2    Kerwin, E.3    Church, N.4    Emmett, A.5    Rickard, K.6
  • 37
    • 33144476873 scopus 로고    scopus 로고
    • The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol
    • SMART Study Group
    • Nelson, H.S., Weiss, S.T., Bleecker, E.R., Yancey, S.W., Dorinsky, P.M.; SMART Study Group. (2006) The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest 129: 15-26.
    • (2006) Chest , vol.129 , pp. 15-26
    • Nelson, H.S.1    Weiss, S.T.2    Bleecker, E.R.3    Yancey, S.W.4    Dorinsky, P.M.5
  • 38
    • 79959344460 scopus 로고    scopus 로고
    • Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007
    • Nih/Nhlbi (2007) Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. J Allergy Clin Immunol 120: S94-138.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. S94-138
    • Nih/Nhlbi1
  • 39
    • 0035016114 scopus 로고    scopus 로고
    • What is “more effective asthma control
    • O'Brien, K. and Bukstein, D. (2001) What is “more effective asthma control”? J Allergy Clin Immunol 107: 1107-1109.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 1107-1109
    • O'Brien, K.1    Bukstein, D.2
  • 40
    • 12144270425 scopus 로고    scopus 로고
    • Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma
    • O'Byrne, P.M., Bisgaard, H., Godard, P.P., Pistolesi, M., Palmqvist, M., Zhu,Y. et al. (2005) Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma. Am J Respir Crit Care Med 171: 129-136.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 129-136
    • O'Byrne, P.M.1    Bisgaard, H.2    Godard, P.P.3    Pistolesi, M.4    Palmqvist, M.5    ZhuY.6
  • 41
    • 1842370350 scopus 로고    scopus 로고
    • Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group
    • Pauwels, R.A., Lofdahl, C.G., Postma, D.S., Tattersfield, A.E., O'Byrne, P., Barnes, P.J. et al. (1997) Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med 337: 1405-1411.
    • (1997) N Engl J Med , vol.337 , pp. 1405-1411
    • Pauwels, R.A.1    Lofdahl, C.G.2    Postma, D.S.3    Tattersfield, A.E.4    O'Byrne, P.5    Barnes, P.J.6
  • 42
    • 0029985810 scopus 로고    scopus 로고
    • Eosinophil and neutrophil activity in asthma in a one-year trial with inhaled budesonide. The impact of smoking
    • Pedersen, B., Dahl, R., Karlstrom, R., Peterson, C.G. and Venge, P. (1996) Eosinophil and neutrophil activity in asthma in a one-year trial with inhaled budesonide. The impact of smoking. Am J Respir Crit Care Med 153: 1519-1529.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 1519-1529
    • Pedersen, B.1    Dahl, R.2    Karlstrom, R.3    Peterson, C.G.4    Venge, P.5
  • 43
    • 7644224295 scopus 로고    scopus 로고
    • The effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis
    • Philip, G., Nayak, A.S., Berger, W.E., Leynadier, F., Vrijens, F., Dass, S.B. et al. (2004) The effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis. Curr Med Res Opin 20: 1549-1558.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1549-1558
    • Philip, G.1    Nayak, A.S.2    Berger, W.E.3    Leynadier, F.4    Vrijens, F.5    Dass, S.B.6
  • 44
    • 0032866048 scopus 로고    scopus 로고
    • Montelukast reduces airway eosinophilic inflammation in asthma: a randomized, controlled trial
    • Pizzichini, E., Leff, J.A., Reiss, T.F., Hendeles, L., Boulet, L.P., Wei, L.X. et al. (1999) Montelukast reduces airway eosinophilic inflammation in asthma: a randomized, controlled trial. Eur Respir J 14: 12-18.
    • (1999) Eur Respir J , vol.14 , pp. 12-18
    • Pizzichini, E.1    Leff, J.A.2    Reiss, T.F.3    Hendeles, L.4    Boulet, L.P.5    Wei, L.X.6
  • 45
    • 0037338743 scopus 로고    scopus 로고
    • Randomised controlled trial of montelukast plus inhaled budesonide versus double dose inhaled budesonide in adult patients with asthma
    • Price, D.B., Hernandez, D., Magyar, P., Fiterman, J., Beeh, K.M., James, I.G. et al. (2003) Randomised controlled trial of montelukast plus inhaled budesonide versus double dose inhaled budesonide in adult patients with asthma. Thorax 58: 211-216.
    • (2003) Thorax , vol.58 , pp. 211-216
    • Price, D.B.1    Hernandez, D.2    Magyar, P.3    Fiterman, J.4    Beeh, K.M.5    James, I.G.6
  • 46
    • 33747761653 scopus 로고    scopus 로고
    • Effect of budesonide in combination with formoterol for reliever therapy in asthma exacerbations: a randomised controlled, double-blind study
    • Rabe, K.F., Atienza, T., Magyar, P., Larsson, P., Jorup, C. and Lalloo, U.G. (2006a) Effect of budesonide in combination with formoterol for reliever therapy in asthma exacerbations: a randomised controlled, double-blind study. Lancet 368: 744-753.
    • (2006) Lancet , vol.368 , pp. 744-753
    • Rabe, K.F.1    Atienza, T.2    Magyar, P.3    Larsson, P.4    Jorup, C.5    Lalloo, U.G.6
  • 47
    • 33344471388 scopus 로고    scopus 로고
    • Budesonide/ formoterol in a single inhaler for maintenance and relief in mild-to-moderate asthma: a randomized, double-blind trial
    • Rabe, K.F., Pizzichini, E., Stallberg, B., Romero, S., Balanzat, A.M., Atienza, T. et al. (2006b) Budesonide/ formoterol in a single inhaler for maintenance and relief in mild-to-moderate asthma: a randomized, double-blind trial. Chest 129: 246-256.
    • (2006) Chest , vol.129 , pp. 246-256
    • Rabe, K.F.1    Pizzichini, E.2    Stallberg, B.3    Romero, S.4    Balanzat, A.M.5    Atienza, T.6
  • 48
    • 0028226021 scopus 로고
    • Reduced protection against exercise induced bronchoconstriction after chronic dosing with salmeterol
    • Ramage, L., Lipworth, B.J., Ingram, C.G., Cree, I.A. and Dhillon, D.P. (1994) Reduced protection against exercise induced bronchoconstriction after chronic dosing with salmeterol. Respir Med 88: 363-368.
    • (1994) Respir Med , vol.88 , pp. 363-368
    • Ramage, L.1    Lipworth, B.J.2    Ingram, C.G.3    Cree, I.A.4    Dhillon, D.P.5
  • 49
    • 33644649189 scopus 로고    scopus 로고
    • Determinants of patient adherence to an aerosol regimen
    • Rau, J.L. (2005) Determinants of patient adherence to an aerosol regimen. Respir Care 50: 1346-1356.
    • (2005) Respir Care , vol.50 , pp. 1346-1356
    • Rau, J.L.1
  • 51
    • 84992816892 scopus 로고    scopus 로고
    • asthma: a multicenter, randomized, double-blind trial. Montelukast Clinical Research Study Group
    • asthma: a multicenter, randomized, double-blind trial. Montelukast Clinical Research Study Group. Arch Intern Med 158: 1213-1220.
    • Arch Intern Med , vol.158 , pp. 1213-1220
  • 52
    • 5444248773 scopus 로고    scopus 로고
    • Efficacy and safety of budesonide/formoterol single inhaler therapy versus a higher dose of budesonide in moderate to severe asthma
    • Scicchitano, R., Aalbers, R., Ukena, D., Manjra, A., Fouquert, L., Centanni, S. et al. (2004) Efficacy and safety of budesonide/formoterol single inhaler therapy versus a higher dose of budesonide in moderate to severe asthma. Curr Med Res Opin 20: 1403-1418.
    • (2004) Curr Med Res Opin , vol.20 , pp. 1403-1418
    • Scicchitano, R.1    Aalbers, R.2    Ukena, D.3    Manjra, A.4    Fouquert, L.5    Centanni, S.6
  • 53
    • 0035002482 scopus 로고    scopus 로고
    • Montelukast added to budesonide in children with persistent asthma: a randomized, double-blind, crossover study
    • Simons, F.E., Villa, J.R., Lee, B.W., Teper, A.M., Lyttle, B., Aristizabal, G. et al. (2001) Montelukast added to budesonide in children with persistent asthma: a randomized, double-blind, crossover study. J Pediatr 138: 694-698.
    • (2001) J Pediatr , vol.138 , pp. 694-698
    • Simons, F.E.1    Villa, J.R.2    Lee, B.W.3    Teper, A.M.4    Lyttle, B.5    Aristizabal, G.6
  • 54
    • 0242575119 scopus 로고    scopus 로고
    • Budesonide/formoterol adjustable maintenance dosing reduces asthma exacerbations versus fixed dosing
    • Stallberg, B., Olsson, P., Jorgensen, L.A., Lindarck, N. and Ekstrom, T. (2003) Budesonide/formoterol adjustable maintenance dosing reduces asthma exacerbations versus fixed dosing. Int J Clin Pract 57: 656-661.
    • (2003) Int J Clin Pract , vol.57 , pp. 656-661
    • Stallberg, B.1    Olsson, P.2    Jorgensen, L.A.3    Lindarck, N.4    Ekstrom, T.5
  • 55
    • 4844221717 scopus 로고    scopus 로고
    • A comparison of the effects of oral montelukast and inhaled salmeterol on response to rescue bronchodilation after challenge
    • Storms, W., Chervinsky, P., Ghannam, A.F., Bird, S., Hustad, C.M. and Edelman, J.M. (2004) A comparison of the effects of oral montelukast and inhaled salmeterol on response to rescue bronchodilation after challenge. Respir Med 98: 1051-1062.
    • (2004) Respir Med , vol.98 , pp. 1051-1062
    • Storms, W.1    Chervinsky, P.2    Ghannam, A.F.3    Bird, S.4    Hustad, C.M.5    Edelman, J.M.6
  • 56
  • 57
    • 33744510422 scopus 로고    scopus 로고
    • High-dose inhaled corticosteroids and add-on therapy use in adults with asthma in the UK in 2003: an observational study
    • Thomas, M., Leather, D. and Price, D. (2006) High-dose inhaled corticosteroids and add-on therapy use in adults with asthma in the UK in 2003: an observational study. Prim Care Respir J 15: 166-172.
    • (2006) Prim Care Respir J , vol.15 , pp. 166-172
    • Thomas, M.1    Leather, D.2    Price, D.3
  • 59
    • 0037342603 scopus 로고    scopus 로고
    • Effect of montelukast added to inhaled budesonide on control of mild to moderate asthma
    • Vaquerizo, M.J., Casan, P., Castillo, J., Perpina, M., Sanchis, J., Sobradillo, V. et al. (2003) Effect of montelukast added to inhaled budesonide on control of mild to moderate asthma. Thorax 58: 204-210.
    • (2003) Thorax , vol.58 , pp. 204-210
    • Vaquerizo, M.J.1    Casan, P.2    Castillo, J.3    Perpina, M.4    Sanchis, J.5    Sobradillo, V.6
  • 60
    • 0032842408 scopus 로고    scopus 로고
    • Montelukast versus salmeterol in patients with asthma and exercise-induced bronchoconstriction. Montelukast/Salmeterol Exercise Study Group
    • Villaran, C., O'Neill, S.J., Helbling, A., van Noord, J.A., Lee, T.H., Chuchalin, A.G. et al. (1999) Montelukast versus salmeterol in patients with asthma and exercise-induced bronchoconstriction. Montelukast/Salmeterol Exercise Study Group. J Allergy Clin Immunol 104: 547-553.
    • (1999) J Allergy Clin Immunol , vol.104 , pp. 547-553
    • Villaran, C.1    O'Neill, S.J.2    Helbling, A.3    van Noord, J.A.4    Lee, T.H.5    Chuchalin, A.G.6
  • 61
    • 33749044069 scopus 로고    scopus 로고
    • Efficacy and safety of montelukast in adults with asthma and allergic rhinitis
    • Virchow, J.C. and Bachert, C. (2006) Efficacy and safety of montelukast in adults with asthma and allergic rhinitis. Respir Med 100: 1952-1959.
    • (2006) Respir Med , vol.100 , pp. 1952-1959
    • Virchow, J.C.1    Bachert, C.2
  • 62
    • 27744557795 scopus 로고    scopus 로고
    • Budesonide/formoterol maintenance and reliever therapy: an effective asthma treatment option?
    • Vogelmeier, C., D'Urzo, A., Pauwels, R., Merino, J.M., Jaspal, M., Boutet, S. et al. (2005) Budesonide/formoterol maintenance and reliever therapy: an effective asthma treatment option? Eur Respir J 26: 819-828.
    • (2005) Eur Respir J , vol.26 , pp. 819-828
    • Vogelmeier, C.1    D'Urzo, A.2    Pauwels, R.3    Merino, J.M.4    Jaspal, M.5    Boutet, S.6
  • 63
    • 9644291519 scopus 로고    scopus 로고
    • Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma
    • Williams, L.K., Pladevall, M., Xi, H., Peterson, E.L., Joseph, C., Lafata, J.E. et al. (2004) Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma. J Allergy Clin Immunol 114: 1288-1293.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 1288-1293
    • Williams, L.K.1    Pladevall, M.2    Xi, H.3    Peterson, E.L.4    Joseph, C.5    Lafata, J.E.6
  • 64
    • 0030479464 scopus 로고    scopus 로고
    • An inhaled glucocorticoid does not prevent tolerance to the bronchoprotective effect of a long-acting inhaled beta 2-agonist
    • Yates, D.H., Kharitonov, S.A. and Barnes, P.J. (1996) An inhaled glucocorticoid does not prevent tolerance to the bronchoprotective effect of a long-acting inhaled beta 2-agonist. Am J Respir Crit Care Med 154: 1603-1607.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 1603-1607
    • Yates, D.H.1    Kharitonov, S.A.2    Barnes, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.