Both all-trans retinoic acid and cytochrome P450 (CYP26) inhibitors affect the expression of vitamin A metabolizing enzymes and retinoid biomarkers in organotypic epidermis

Archives of Dermatological Research

Volumn 301, Issue 7, 2009, Pages 475-485

  Pavez Loriè, Elizabeth ^a   Chamcheu, Jean Christopher ^a   Vahlquist, Anders ^a   Törmä, Hans ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

CYP26; Metabolism; RAMBA

Indexed keywords

BINDING PROTEIN; BIOLOGICAL MARKER; CELLULAR RETINOIC ACID BINDING PROTEIN 2; CYTOCHROME P450 26A1; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; KERATIN; KERATIN INTERMEDIATE FILAMENT 2; KERATIN INTERMEDIATE FILAMENT 4; LECITHIN RETINOL ACYLTRANSFERASE; LIAROZOLE; MESSENGER RNA; N [4 [2 ETHYL 1 (1H 1,2,4 TRIAZOL 1 YL)BUTYL]PHENYL] 2 BENZOTHIAZOLAMINE; R 075251; RETINOIC ACID; RETINOID; RETINOL; RETINOL DEHYDROGENASE; RETINOL DEHYDROGENASE 16; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; BIOACCUMULATION; BIOSYNTHESIS; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; ENZYME INHIBITION; EPIDERMIS; ESTERIFICATION; GENE EXPRESSION; GENETIC REGULATION; HUMAN; HUMAN CELL; INTERMEDIATE FILAMENT; KERATINOCYTE; NEWBORN; PRIORITY JOURNAL;

ACYLTRANSFERASES; ALCOHOL OXIDOREDUCTASES; ANDROGEN ANTAGONISTS; BENZOTHIAZOLES; BIOLOGICAL MARKERS; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; EPIDERMIS; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IMIDAZOLES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATIN-2; KERATIN-4; KERATINOCYTES; RECEPTORS, RETINOIC ACID; RETINAL DEHYDROGENASE; TRETINOIN; TRIAZOLES; VITAMIN A;

EID: 68649117375     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-009-0937-7     Document Type: Article

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