Expression of retinoid-regulated genes in lamellar ichthyosis vs. healthy control epidermis: Changes after oral treatment with liarozole

Acta Dermato-Venereologica

Volumn 89, Issue 1, 2009, Pages 12-20

  Pavez Loriè, Elizabeth ^a   Gånemo, Agneta ^a   Borgers, Marcel ^b   Wouters, Luc ^b   Blockhuys, Stan ^b   Van de Plassche, Lieve ^b   Törmä, Hans ^a   Vahlquist, Anders ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b Barrier Therapeutics nv   (Belgium)

Author keywords

Cytochrome P450, skin disorders; Keratin; Retinoic acid metabolism blocking agents; Vitamin A metabolism

Indexed keywords

CYTOCHROME P450 26A1; CYTOKERATIN 2; CYTOKERATIN 4; INTERLEUKIN 1ALPHA; LIAROZOLE; MESSENGER RNA; PLACEBO; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; RETINOIC ACID BINDING PROTEIN; RETINOID; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; EPIDERMIS; FEMALE; GENE CONTROL; GENE EXPRESSION; GENETIC MARKER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LAMELLAR ICHTHYOSIS; MALE; MULTICENTER STUDY; PHARMACOGENETICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SKIN BIOPSY; SYSTEMIC DISEASE;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGED; BIOLOGICAL MARKERS; DERMATOLOGIC AGENTS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; ICHTHYOSIS, LAMELLAR; IMIDAZOLES; INTERLEUKIN-1ALPHA; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; RECEPTORS, RETINOIC ACID; RNA, MESSENGER; SKIN; TRETINOIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58549100950     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: 10.2340/00015555-0573     Document Type: Article

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