Methylation of the PTEN gene CpG island is infrequent in juvenile myelomonocytic leukemia: Comments on "PTEN deficiency is a common defect in juvenile myelomonocytic leukemia" [Leuk. Res. 2009;33:671-677 (Epub 2008 November 17)]

Leukemia Research

Volumn 33, Issue 11, 2009, Pages 1578-1579

  Batz, Christiane ^a   Sandrock, Inga ^a   Niemeyer, Charlotte M ^a   Flotho, Christian ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

CONTROLLED STUDY; CPG ISLAND; DENATURING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; DNA METHYLATION; EPIGENETICS; GEOGRAPHIC DISTRIBUTION; HUMAN; JUVENILE MYELOMONOCYTIC LEUKEMIA; LETTER; MAJOR CLINICAL STUDY; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION SITE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CPG ISLANDS; DNA METHYLATION; HUMANS; LEUKEMIA, MYELOMONOCYTIC, JUVENILE; PTEN PHOSPHOHYDROLASE;

EID: 68649098476     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2009.04.040     Document Type: Letter

References (4)

1. Liu YL, Castleberry RP, Emanuel PD. PTEN deficiency is a common defect in juvenile myelomonocytic leukemia. Leukemia Research 2009;33:671-677 (Epub Nov 17,2008).
2. Zysman M.A., Chapman W.B., and Bapat B. Considerations when analysing the methylation status of PTEN tumor suppressor gene. American Journal of Pathology 160 (2002) 795-800
3. Perry A.S., Liyanage H., Lawler M., and Woodson K. Discovery of DNA hypermethylation using a DHPLC screening strategy. Epigenetics 2 (2007) 43-49
4. Betz B., Florl A.R., Seifert H.H., Dall P., Schulz W.A., and Niederacher D. Denaturing high-performance liquid chromatography (DHPLC) as a reliable high-throughput prescreening method for aberrant promoter methylation in cancer. Human Mutations 23 (2004) 612-620