Preoperative irradiation affects functional results after surgery for rectal cancer: Results from a randomized study

Diseases of the Colon and Rectum

Volumn 41, Issue 5, 1998, Pages 543-549

  Dahlberg, Michael ^a   Glimelius, Bengt ^a   Graf, Wilhelm ^a   Påhlman, Lars ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Anorectal function; Anterior resection syndrome; Radiotherapy; Rectal cancer

Indexed keywords

ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER RECURRENCE; CLINICAL TRIAL; COLORECTAL CANCER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; INTESTINE FUNCTION; MAJOR CLINICAL STUDY; MALE; PREOPERATIVE TREATMENT; RADIATION DOSE; RANDOMIZED CONTROLLED TRIAL; RECTUM ANTERIOR RESECTION; RECTUM CANCER; TREATMENT OUTCOME;

EID: 0031978182     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02235256     Document Type: Article

References (38)

1. Nicholls RJ, Ritchie JK, Wadsworth J, Parks AG. Total excision or restorative resection for carcinoma of the middle third of the rectum. Br J Surg 1979;66:625-7.
2. Williams NS, Johnston D. Survival and recurrence after sphincter saving resection and abdominoperineal resection for carcinoma of the middle third of the rectum. Br J Surg 1984;71:278-82.
3. Odou MW, O'Connel TX. Changes in the treatment of rectal carcinoma and effects on local recurrence. Arch Surg 1986;121:1114-6.
4. Påhlman L, Glimelius B. Radiotherapy additional to surgery in the management of primary rectal carcinoma. Acta Chir Scand 1990;156:475-85.
5. Williams NS, Johnston D. The quality of life after rectal excision of low rectal cancer. Br J Surg 1983; 70:460-2.
6. Frigell A, Ottander M, Stenbeck H, Påhlman L. Quality of life of patients treated with abdominoperineal resection or anterior resection for rectal carcinoma. Ann Chir Gynaecol 1990;79:26-30.
7. Swedish Rectal Cancer Trial. Local recurrence rate in a randomized multicentre trial of preoperative radiotherapy compared to surgery alone in resectable rectal carcinoma. Eur J Surg 1996;162:397-402.
8. Marsh PJ, James RD, Schofield PF. Adjuvant preoperative radiotherapy for locally advanced rectal carcinoma: results of a prospective randomized trial. Dis Colon Rectum 1994;37:1205-14.
9. Påhlman L, Glimelius B. Pre- and postoperative radiotherapy in rectal carcinoma: report from a randomized multicentre trial. Ann Surg 1990;211:187-95.
10. Gérard A, Buyse M, Nordlinger B, et al. Preoperative radiotherapy as adjuvant treatment in rectal cancer. Ann Surg 1988;208:606-14.
11. Stockholm Rectal Cancer Study Group. Preoperative short-term radiation therapy in operable rectal carcinoma: a prospective randomized trial. Cancer 1990;66: 49-55.
12. Buyse M, Zeleniuch-Jacuotte A, Chalmes TC. Adjuvant therapy of colorectal cancer: why we still don't know. JAMA 1988;259:3571-8.
13. Swedish Rectal Cancer Trial. Preoperative radiotherapy improves survival in resectable rectal carcinoma: report from a nation-wide Swedish trial. N Engl J Med 1997; 336:980-7.
14. Cedermark B, for the Stockholm Colo-Rectal Cancer Study Group. Randomized study on preoperative radiotherapy in rectal carcinoma. Ann Surg Oncol 1996;3: 423-30.
15. Påhlman L, Glimelius B, Graffman S. Pre- versus postoperative radiotherapy in rectal carcinoma: an interim report from a randomized multicentre trial. Br J Surg 1985;72:961-6.
16. Swedish Rectal Cancer Trial. Initial report from a Swedish multicentre study examining the role of preoperative irradiation in the treatment of patients with resectable rectal carcinoma. Br J Surg 1993;80:1333-6.
17. Frykholm GJ, Glimelius B. Påhlman L. Preoperative or postoperative irradiation in adenocarcinoma of the rectum: final treatment results of a randomized trial and an evaluation of late secondary effects. Dis Colon Rectum 1993;36:564-72.
18. Holm T, Singnomklao T, Rutqvist LE, Cedermark B. Adjuvant preoperative radiotherapy in patients with rectal carcinoma: adverse effects during long term follow-up of two randomized trials. Cancer 1996;78: 968-76.
19. Graf W, Ekström K, Glimelius B, Påhlman L. A pilot study of factors influencing bowel function after colorectal anastomosis. Dis Colon Rectum 1996;39:744-9.
20. Paty PB, Enker WE, Cohen AM, Minsky BD, Friedlander-Klar H. Long-term functional results of coloanal anastomosis for rectal cancer. Am J Surg 1994;167:90-5.
21. Lewis WG, Williamson ME, Kuzu A, et al. Potential disadvantages of postoperative radiotherapy after anterior resection for rectal cancer: a pilot study of sphincter function, rectal capacity and clinical outcome. Int J Colorectal Dis 1995;10:133-7.
22. McDonald PJ, Heald RJ. A survey of postoperative function after rectal anastomosis with circular stapling devices. Br J Surg 1983;70:727-9.
23. Batignani G, Monaci I, Ficari F, Tonelli F. What affects continence after anterior resection of the rectum? Dis Colon Rectum 1991;34:329-35.
24. Horgan PG, O'Connell PR, Shinkwin CA, Kirwan WO. Effect of anterior resection on anal sphincter function. Br J Surg 1989;76:783-6.
25. Molloy RG, Moran KT, Coulter J, Waldron R, Kirwan WO. Mechanism of sphincter impairment following low anterior resection. Dis Colon Rectum 1992;35:462-4.
26. O'Riordain MG, Molloy RG, Gillen P, Morgan A, Kirwan WO. Rectoanal inhibitory reflex following low stapled anterior resection of the rectum. Dis Colon Rectum 1992;35:874-8.
27. Pedersen IK, Hint K, Olsen J, Christiansen J, Jensen P, Mortensen P. Anorectal function after low anterior resection for carcinoma. Ann Surg 1986;204:133-5.
28. Nakahara S, Itoh H, Mibu R, et al. Clinical and manometric evaluation of anorectal function following low anterior resection with low anastomotic line using an EEA™ stapler for rectal cancer. Dis Colon Rectum 1988; 31:762-6.
29. Fowler JF. The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol 1989;62:679-94.
30. Emami B, Lyman J, Brown A, et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys 1991;21:109-22.
31. Coia LR, Myerson RJ, Tepper JE. Late effects of radiation therapy on gastrointestinal tract. Int J Radiat Oncol Biol Phys 1995;31:1213-36.
32. Gillette EL, Mahler PA, Powers BE, Gillette SM, Vujaskovic Z. Late radiation injury to muscle and peripheral nerves. Int J Radiat Oncol Biol Phys 1995;31: 1309-18.
33. Birnbaum EH, Myerson RJ, Fry RD, Kodner IJ, Fleshman JW. Chronic effects of pelvic radiation therapy on anorectal function. Dis Colon Rectum 1994;37:909-15.
34. Stoll BA, Andrews JT. Radiation induced peripheral neuropathy. BMJ 1966;1:834-7.
35. Frykholm GJ, Isacsson U, Nygard K, et al. Preoperative radiotherapy in rectal carcinoma - aspects of acute adverse effects and radiation technique. Int J Radiat Oncol Biol Phys 1996;35:1039-48.
36. Karanjia ND, Scache DJ, Heald RJ. Function of the distal rectum after low anterior resection for carcinoma. Br J Surg 1992;79;114-6.
37. Carmona JA, Ortiz H, Perez-Cabanas I. Alterations in anorectal function after anterior resection for cancer of the rectum. Int J Colorectal Dis 1991;6:108-10.
38. Ho YH, Wong J, Goh HS. Level of anastomosis and anorectal manometry in predicting function following anterior resection for adenocarcinoma. Int J Colorectal Dis 1993;8:170-4.