Visuospatial working memory deficits and visual pursuit impairments are not directly related in schizophrenia

Australian and New Zealand Journal of Psychiatry

Volumn 43, Issue 8, 2009, Pages 766-774

  Cocchi, Luca ^a,b,c   Bosisio, Francesca ^a   Carter, Olivia ^c   Wood, Stephen ^c   Berchtold, Andre ^a   Conus, Philippe ^d   Orita, Alina ^d   Debbané, Martin ^e   Schenk, Francoise ^a,b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b Hopital de Cery   (Switzerland)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d DEPT UNIV DE PSYCHIATRIE ADULTE   (Switzerland)

^e UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

Encoding; Eye movements; Schizophrenia; Visual pursuit; Working memory

Indexed keywords

ACCURACY; ADULT; ANALYTICAL ERROR; ARTICLE; CLINICAL ARTICLE; COMPACT DISK; CONTROLLED STUDY; DEPTH PERCEPTION; EPISODIC MEMORY; EYE MOVEMENT DISORDER; EYE TRACKING; FEMALE; HEAD MOVEMENT; HUMAN; INFORMATION PROCESSING; MALE; MEMORY DISORDER; PATTERN RECOGNITION; PERCEPTION DISORDER; PERCEPTIVE THRESHOLD; SCHIZOPHRENIA; SPATIAL DISCRIMINATION; TASK PERFORMANCE; WORKING MEMORY;

ADULT; CASE-CONTROL STUDIES; FEMALE; HUMANS; MALE; MEMORY DISORDERS; OCULOMOTOR MUSCLES; PURSUIT, SMOOTH; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY;

EID: 68549123499     PISSN: 00048674     EISSN: 14401614     Source Type: Journal    
DOI: 10.1080/00048670903001901     Document Type: Article

References (24)

1. Wood SJ, Pantelis C, Proffitt T et al. Spatial working memory ability is a marker of risk-for-psychosis. Psychol Med 2003; 33:1239-1247.
2. Hong LE, Mitchell BD, Avila MT, Adami H, McMahon RP, Thaker GK. Familial aggregation of eye-tracking endophenotypes in families of schizophrenic patients. Arch Gen Psychiatry 2006; 63:259-264.
3. Thaker GK, Avila MT, Hong EL, Medoff DR, Ross DE, Adami HM. A model of smooth pursuit eye movement deficit associated with the schizophrenia phenotype. Psychophysiology 2003; 40:277-284.
4. Nagel M, Sprenger A, Hohagen F, Binkofski F, Lencer R. Cortical mechanisms of retinal and extraretinal smooth pursuit eye movements to different target velocities. Neuroimage 2008; 41:483-492.
5. Nagel M, Sprenger A, Zapf S et al. Parametric modulation of cortical activation during smooth pursuit with and without target blanking: An fMRI study. Neuroimage 2006; 29: 1319-1325.
6. Pierrot-Deseilligny C, Milea D, Muri RM. Eye movement control by the cerebral cortex. Curr Opin Neurol 2004; 17: 17-25.
7. Snitz BE, Curtis CE, Zald DH, Katsanis J, Iacono WG. Neuropsychological and oculomotor correlates of spatial working memory performance in schizophrenia patients and controls. Schizophr Res 1999; 38:37-50.
8. ParkS, Holzman PS. Association of working memory deficit and eye tracking dysfunction in schizophrenia. Schizophr Res 1993; 11:55-61.
9. Katsanis J, Iacono WG. Clinical, neuropsychological, and brain structural correlates of smooth-pursuit eye tracking performance in chronic schizophrenia. J Abnorm Psychol 1991; 100:526-534.
10. Litman RE, Hommer DW, Clem T, Ornsteen ML, Ollo C, Pickar D. Correlation of Wisconsin Card Sorting Test performance with eye tracking in schizophrenia. Am J Psychiatry 1991; 148:1580-1582.
11. Hutton SB, Huddy V, Barnes TR et al. The relationship between antisaccades, smooth pursuit, and executive dysfunction in first-episode schizophrenia. Biol Psychiatry 2004; 56:553-559.
12. Cocchi L, SchenkF, Volken H, Bovet P, Parnas J, Vianin P. Visuo-spatial processing in a dynamic and a static working memory paradigm in schizophrenia. Psychiatry Res 2007; 152:129-142.
13. Sheehan DV, Lecrubier Y, Sheehan KH et al. The Mini- International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998; 59 (Suppl 20):22-33; quiz 4-57.
14. Woods SW. Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry 2003; 64:663-667.
15. Leucht S, WahlbeckK, Hamann J, Kissling W. New generation antipsychotics versus low-potency conventional antipsychotics: A systematic review and meta-analysis. Lancet 2003; 361(9369):1581-1589.
16. Gitelman DR. ILAB: A program for postexperimental eye movement analysis. Behav Res Methods Instrum Comput 2002; 34:605-612.
17. Kojima T, Matsushima E, Ando K et al. Exploratory eye movements and neuropsychological tests in schizophrenic patients. Schizophr Bull 1992; 18:85-94.
18. Phillips ML, David AS. Abnormal visual scan paths: A psychophysiological marker of delusions in schizophrenia. Schizophr Res 1998; 29:235-245.
19. Holzman PS. Eye movements and the search for the essence of schizophrenia. Brain Res Brain Res Rev 2000; 31:350-356.
20. Petit L, Beauchamp MS. Neural basis of visually guided head movements studied with fMRI. J Neurophysiol 2003; 89: 2516-2527.
21. van Haren NE, Hulshoff Pol HE, SchnackHG et al. Focal gray matter changes in schizophrenia across the course of the illness: A 5-year follow-up study. Neuropsychopharmacology 2007; 32:2057-2066.
22. van Haren NE, Hulshoff Pol HE, SchnackHG et al. Progressive brain volume loss in schizophrenia over the course of the illness: Evidence of maturational abnormalities in early adulthood. Biol Psychiatry 2008; 63:106-113.
23. Lee J, ParkS. Working memory impairments in schizophrenia: A meta-analysis. J Abnorm Psychol 2005; 114:599-611.
24. Perlstein WM, Carter CS, Noll DC, Cohen JD. Relation of prefrontal cortex dysfunction to working memory and symptoms in schizophrenia. Am J Psychiatry 2001; 158: 1105-1113.