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Volumn 8, Issue 4, 2009, Pages 273-283

Dynamic compression inhibits fibronectin fragment induced iNOS and COX-2 expression in chondrocyte/agarose constructs

Author keywords

NO; Cartilage; COX 2; FN f; INOS; Mechanotransduction; PGE2

Indexed keywords

CELL PROLIFERATION; CELL SIGNALING; DYNAMICS;

EID: 68549122712     PISSN: 16177959     EISSN: 16822978     Source Type: Journal    
DOI: 10.1007/s10237-008-0134-1     Document Type: Article
Times cited : (5)

References (55)
  • 2
    • 0029100088 scopus 로고
    • Signal transduction through chondrocyte integrin receptors induces matrix metalloproteinase synthesis and synergizes with interleukin-1
    • EC Arner MD Tortorella 1995 Signal transduction through chondrocyte integrin receptors induces matrix metalloproteinase synthesis and synergizes with interleukin-1 Arthritis Rheum 38 9 1304 1314
    • (1995) Arthritis Rheum , vol.38 , Issue.9 , pp. 1304-1314
    • Arner, E.C.1    Tortorella, M.D.2
  • 3
    • 34249815837 scopus 로고    scopus 로고
    • Mechanical regulation of MMPs
    • EJ Blain 2007 Mechanical regulation of MMPs Front Biosci 12 507 527
    • (2007) Front Biosci , vol.12 , pp. 507-527
    • Blain, E.J.1
  • 4
    • 0036978326 scopus 로고    scopus 로고
    • The effect of cyclical compressive loading on gene expression in articular cartilage
    • EJ Blain DJ Mason VC Duance 2001 The effect of cyclical compressive loading on gene expression in articular cartilage Biorheology 40 111 117
    • (2001) Biorheology , vol.40 , pp. 111-117
    • Blain, E.J.1    Mason, D.J.2    Duance, V.C.3
  • 9
    • 0043063935 scopus 로고    scopus 로고
    • Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression
    • TT Chowdhury DL Bader JC Shelton DA Lee 2003 Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression Arch Biochem Biophys 417 105 111
    • (2003) Arch Biochem Biophys , vol.417 , pp. 105-111
    • Chowdhury, T.T.1    Bader, D.L.2    Shelton, J.C.3    Lee, D.A.4
  • 10
    • 33747088826 scopus 로고    scopus 로고
    • Dynamic compression counteracts IL-1beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs
    • TT Chowdhury DL Bader DA Lee 2006 Dynamic compression counteracts IL-1beta induced iNOS and COX-2 activity by human chondrocytes cultured in agarose constructs Biorheology 43 413 429
    • (2006) Biorheology , vol.43 , pp. 413-429
    • Chowdhury, T.T.1    Bader, D.L.2    Lee, D.A.3
  • 11
    • 42049112399 scopus 로고    scopus 로고
    • Dynamic compression counteracts IL-1β induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs
    • TT Chowdhury S Arghandawi J Brand OO Akanji DL Bader DM Salter DA Lee 2008 Dynamic compression counteracts IL-1β induced inducible nitric oxide synthase and cyclo-oxygenase-2 expression in chondrocyte/agarose constructs Arthritis Res Ther 10 2 R35
    • (2008) Arthritis Res Ther , vol.10 , Issue.2 , pp. 35
    • Chowdhury, T.T.1    Arghandawi, S.2    Brand, J.3    Akanji, O.O.4    Bader, D.L.5    Salter, D.M.6    Lee, D.A.7
  • 12
    • 0036171665 scopus 로고    scopus 로고
    • Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species
    • M Del Carlo Jr RF Loeser 2002 Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species Arthritis Rheum 46 2 394 403
    • (2002) Arthritis Rheum , vol.46 , Issue.2 , pp. 394-403
    • Del Carlo Jr, M.1    Loeser, R.F.2
  • 13
    • 33947511182 scopus 로고    scopus 로고
    • Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments
    • M Del Carlo D Schwartz EA Erickson R Loeser 2007 Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments Free Radical Biol Med 42 1350 1358
    • (2007) Free Radical Biol Med , vol.42 , pp. 1350-1358
    • Del Carlo, M.1    Schwartz, D.2    Erickson, E.A.3    Loeser, R.4
  • 14
  • 16
    • 0036746088 scopus 로고    scopus 로고
    • Fibronectin fragments and blocking antibodies to alpha2beta1 and alpha5beta1 integrins stimulate mitogen-activated protein kinase signaling and increase collagenase 3 (matrix metalloproteinase 13) production by human articular chondrocytes
    • CB Forsyth J Pulai RF Loeser 2002 Fibronectin fragments and blocking antibodies to alpha2beta1 and alpha5beta1 integrins stimulate mitogen-activated protein kinase signaling and increase collagenase 3 (matrix metalloproteinase 13) production by human articular chondrocytes Arthritis Rheum 46 9 2368 2376
    • (2002) Arthritis Rheum , vol.46 , Issue.9 , pp. 2368-2376
    • Forsyth, C.B.1    Pulai, J.2    Loeser, R.F.3
  • 17
    • 0037059836 scopus 로고    scopus 로고
    • Focal adhesion kinase and mitogen-activated protein kinases are involved in chondrocyte activation by the 29-kDa amino-terminal fibronectin fragment
    • T Gemba J Valbracht S Alsalmeh M Lotz 2002 Focal adhesion kinase and mitogen-activated protein kinases are involved in chondrocyte activation by the 29-kDa amino-terminal fibronectin fragment J Biol Chem 277 2 907 911
    • (2002) J Biol Chem , vol.277 , Issue.2 , pp. 907-911
    • Gemba, T.1    Valbracht, J.2    Alsalmeh, S.3    Lotz, M.4
  • 18
    • 27244432788 scopus 로고    scopus 로고
    • The role of mechanical loading in the onset and progression of osteoarthritis
    • TM Griffin F Guilak 2005 The role of mechanical loading in the onset and progression of osteoarthritis Exerc Sport Sci Rev 33 4 195 200
    • (2005) Exerc Sport Sci Rev , vol.33 , Issue.4 , pp. 195-200
    • Griffin, T.M.1    Guilak, F.2
  • 20
    • 0033569125 scopus 로고    scopus 로고
    • Potential regulation of cartilage metabolism in osteoarthritis by fibronectin fragments
    • Malemud CJ (ed) Special issue "fundamental pathways in osteoarthritis"
    • Homandberg GA (1999) Potential regulation of cartilage metabolism in osteoarthritis by fibronectin fragments. In: Malemud CJ (ed) Special issue "fundamental pathways in osteoarthritis". Front Biosci 4:D713-D730
    • (1999) Front Biosci , vol.4
    • Homandberg, G.A.1
  • 21
    • 0030588252 scopus 로고    scopus 로고
    • Association of proteoglycan degradation with catabolic cytokine and stromelysin release from cartilage cultured with fibronectin fragments
    • GA Homandberg F Hui 1996 Association of proteoglycan degradation with catabolic cytokine and stromelysin release from cartilage cultured with fibronectin fragments Arch Biochem Biophys 334 2 325 331
    • (1996) Arch Biochem Biophys , vol.334 , Issue.2 , pp. 325-331
    • Homandberg, G.A.1    Hui, F.2
  • 22
    • 0026731793 scopus 로고
    • Fibronectin fragments cause chondrolysis of bovine articular cartilage slices in culture
    • GA Homandberg R Meyers D Xie 1992 Fibronectin fragments cause chondrolysis of bovine articular cartilage slices in culture J Biol Chem 267 6 3597 3604
    • (1992) J Biol Chem , vol.267 , Issue.6 , pp. 3597-3604
    • Homandberg, G.A.1    Meyers, R.2    Xie, D.3
  • 23
    • 0031057650 scopus 로고    scopus 로고
    • Fibronectin-fragment-induced cartilage chondrolysis is associated with release of catabolic cytokines
    • GA Homandberg F Hui C Wen C Purple K Bewsey H Koepp K Huch A Harris 1997 Fibronectin-fragment-induced cartilage chondrolysis is associated with release of catabolic cytokines Biochem J 321 3 751 757
    • (1997) Biochem J , vol.321 , Issue.3 , pp. 751-757
    • Homandberg, G.A.1    Hui, F.2    Wen, C.3    Purple, C.4    Bewsey, K.5    Koepp, H.6    Huch, K.7    Harris, A.8
  • 24
    • 0032127059 scopus 로고    scopus 로고
    • Cartilage damaging activities of the fibronectin fragments derived from cartilage and synovial fluid
    • GA Homandberg C Wen F Hui 1998 Cartilage damaging activities of the fibronectin fragments derived from cartilage and synovial fluid Osteoarthr Cartil 6 231 244
    • (1998) Osteoarthr Cartil , vol.6 , pp. 231-244
    • Homandberg, G.A.1    Wen, C.2    Hui, F.3
  • 25
    • 0842323826 scopus 로고    scopus 로고
    • Fibronectin fragments cause release and degradation of collagen-binding molecules from equine explant cultures
    • A Johnson R Smith T Saxne M Hickery D Heinegard 2003 Fibronectin fragments cause release and degradation of collagen-binding molecules from equine explant cultures Osteoarthr Cartil 12 149 159
    • (2003) Osteoarthr Cartil , vol.12 , pp. 149-159
    • Johnson, A.1    Smith, R.2    Saxne, T.3    Hickery, M.4    Heinegard, D.5
  • 26
    • 0023616963 scopus 로고
    • An immunohistochemical study of fibronectin in human osteoarthritic and disease-free articular cartilage
    • KL Jones M Brown SY Ali RA Brown 1987 An immunohistochemical study of fibronectin in human osteoarthritic and disease-free articular cartilage Ann Rheum Dis 46 809 815
    • (1987) Ann Rheum Dis , vol.46 , pp. 809-815
    • Jones, K.L.1    Brown, M.2    Ali, S.Y.3    Brown, R.A.4
  • 27
    • 3442883589 scopus 로고    scopus 로고
    • Molecular diffusion in tissue-engineered cartilage constructs: Effects of scaffold material, time, and culture conditions
    • HA Leddy HA Awad F Guilak 2004 Molecular diffusion in tissue-engineered cartilage constructs: effects of scaffold material, time, and culture conditions J Biomed Mater Res B Appl Biomater 70 2 397 406
    • (2004) J Biomed Mater Res B Appl Biomater , vol.70 , Issue.2 , pp. 397-406
    • Leddy, H.A.1    Awad, H.A.2    Guilak, F.3
  • 28
    • 0031105663 scopus 로고    scopus 로고
    • Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose
    • DA Lee DL Bader 1997 Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose J Orthop Res 15 181 188
    • (1997) J Orthop Res , vol.15 , pp. 181-188
    • Lee, D.A.1    Bader, D.L.2
  • 29
    • 16644403620 scopus 로고    scopus 로고
    • Mechanical loading of chondrocytes embedded in 3D constructs: In vitro methods for assessment of morphological and metabolic response to compressive strain
    • DA Lee MM Knight 2004 Mechanical loading of chondrocytes embedded in 3D constructs: in vitro methods for assessment of morphological and metabolic response to compressive strain Methods Mol Med 100 307 324
    • (2004) Methods Mol Med , vol.100 , pp. 307-324
    • Lee, D.A.1    Knight, M.M.2
  • 30
    • 33646477967 scopus 로고    scopus 로고
    • Molecular mechanisms of cartilage destruction: Mechanics, inflammatory mediators, and aging collide
    • RF Loeser 2006 Molecular mechanisms of cartilage destruction: mechanics, inflammatory mediators, and aging collide Arthritis Rheum 54 5 1357 1360
    • (2006) Arthritis Rheum , vol.54 , Issue.5 , pp. 1357-1360
    • Loeser, R.F.1
  • 31
    • 0042090276 scopus 로고    scopus 로고
    • Fibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathway
    • RF Loeser CB Forsyth AM Samarel HJ Im 2003 Fibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathway J Biol Chem 278 27 24577 24585
    • (2003) J Biol Chem , vol.278 , Issue.27 , pp. 24577-24585
    • Loeser, R.F.1    Forsyth, C.B.2    Samarel, A.M.3    Im, H.J.4
  • 32
    • 7944226150 scopus 로고    scopus 로고
    • Altered patterns and synthesis of extracellular matrix macromolecules in early OA
    • P Lorenzo MT Bayliss D Heinegard 2004 Altered patterns and synthesis of extracellular matrix macromolecules in early OA Matrix Biol 23 381 391
    • (2004) Matrix Biol , vol.23 , pp. 381-391
    • Lorenzo, P.1    Bayliss, M.T.2    Heinegard, D.3
  • 33
    • 0033036389 scopus 로고    scopus 로고
    • The role of nitric oxide in articular cartilage damage
    • M Lotz 1999 The role of nitric oxide in articular cartilage damage Rheum Dis Clin North Am 25 269 282
    • (1999) Rheum Dis Clin North Am , vol.25 , pp. 269-282
    • Lotz, M.1
  • 36
    • 0032215333 scopus 로고    scopus 로고
    • Effects of fibronectin on articular cartilage chondrocyte proteoglycan synthesis and response to IGF-1
    • JA Martin JA Buckwalter 1998 Effects of fibronectin on articular cartilage chondrocyte proteoglycan synthesis and response to IGF-1 J Orthop Res 16 6 752 757
    • (1998) J Orthop Res , vol.16 , Issue.6 , pp. 752-757
    • Martin, J.A.1    Buckwalter, J.A.2
  • 37
    • 5444228751 scopus 로고    scopus 로고
    • Protein kinases in chondrocyte signalling and osteoarthritis
    • CJ Malemud 2004 Protein kinases in chondrocyte signalling and osteoarthritis Clin Orthop Relat Res Suppl 427 145 151
    • (2004) Clin Orthop Relat Res , vol.427 , pp. 145-151
    • Malemud, C.J.1
  • 38
    • 2942624012 scopus 로고    scopus 로고
    • Integrin-dependent signal cascades in chondrocyte mechanotransduction
    • SJ Millward-Sadler DM Salter 2004 Integrin-dependent signal cascades in chondrocyte mechanotransduction Ann Biomed Eng 32 435 446
    • (2004) Ann Biomed Eng , vol.32 , pp. 435-446
    • Millward-Sadler, S.J.1    Salter, D.M.2
  • 39
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group wise comparison and statistical analysis of relative expression results in real time PCR
    • MW Pfaffl GW Horgan L Dempfle 2002 Relative expression software tool (REST) for group wise comparison and statistical analysis of relative expression results in real time PCR Nucleic Acids Res 30 e3
    • (2002) Nucleic Acids Res , vol.30 , pp. 3
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 40
    • 4344566132 scopus 로고    scopus 로고
    • Fibronectin fragments elevate nitric oxide (NO) and inducible NO synthetase (iNOS) levels in bovine cartilage and iNOS inhibitors block fibronectin fragment mediated damage and promote repair
    • R Pichika GA Homandberg 2004 Fibronectin fragments elevate nitric oxide (NO) and inducible NO synthetase (iNOS) levels in bovine cartilage and iNOS inhibitors block fibronectin fragment mediated damage and promote repair Inflamm Res 53 8 405 412
    • (2004) Inflamm Res , vol.53 , Issue.8 , pp. 405-412
    • Pichika, R.1    Homandberg, G.A.2
  • 41
    • 0033387185 scopus 로고    scopus 로고
    • Down-regulation of chondrocyte aggrecan and type-II collagen gene expression correlates with increases in static compression magnitude and duration
    • PM Ragan AM Badger M Cook VI Chin M Gowen AJ Grodzinsky MW Lark 1999 Down-regulation of chondrocyte aggrecan and type-II collagen gene expression correlates with increases in static compression magnitude and duration J Orthop Res 17 836 842
    • (1999) J Orthop Res , vol.17 , pp. 836-842
    • Ragan, P.M.1    Badger, A.M.2    Cook, M.3    Chin, V.I.4    Gowen, M.5    Grodzinsky, A.J.6    Lark, M.W.7
  • 42
    • 0026448197 scopus 로고
    • Fluorimetric DNA assay for cell growth estimation
    • J Rao WR Otto 1991 Fluorimetric DNA assay for cell growth estimation Anal Biochem 207 186 192
    • (1991) Anal Biochem , vol.207 , pp. 186-192
    • Rao, J.1    Otto, W.R.2
  • 43
    • 33847219960 scopus 로고    scopus 로고
    • Inflammatory signaling in cartilage: MAPK and NF-kappaB pathways in chondrocytes and the use of inhibitors for research into pathogenesis and therapy of osteoarthritis
    • J Saklatvala 2007 Inflammatory signaling in cartilage: MAPK and NF-kappaB pathways in chondrocytes and the use of inhibitors for research into pathogenesis and therapy of osteoarthritis Curr Drug Targets 8 2 305 313
    • (2007) Curr Drug Targets , vol.8 , Issue.2 , pp. 305-313
    • Saklatvala, J.1
  • 45
    • 0037093523 scopus 로고    scopus 로고
    • The 45 kDa collagen-binding fragment o fibronectin induces MMP-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases
    • H Stanton L Ung AJ Fosang 2002 The 45 kDa collagen-binding fragment o fibronectin induces MMP-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases Biochem J 364 181 190
    • (2002) Biochem J , vol.364 , pp. 181-190
    • Stanton, H.1    Ung, L.2    Fosang, A.J.3
  • 47
    • 34547609625 scopus 로고    scopus 로고
    • NOS and COX interactions in cartilage and meniscus: Relationships to joint physiology, arthritis and tissue repair
    • JB Weinberg B Fermor F Guilak 2007 NOS and COX interactions in cartilage and meniscus: relationships to joint physiology, arthritis and tissue repair Subcell Biochem 42 31 62
    • (2007) Subcell Biochem , vol.42 , pp. 31-62
    • Weinberg, J.B.1    Fermor, B.2    Guilak, F.3
  • 48
    • 0027367049 scopus 로고
    • Fibronectin fragments alter matrix protein synthesis in cartilage tissue cultured in vitro
    • D Xie F Hua GA Homandberg 1993 Fibronectin fragments alter matrix protein synthesis in cartilage tissue cultured in vitro Arch Biophys 307 1 110 118
    • (1993) Arch Biophys , vol.307 , Issue.1 , pp. 110-118
    • Xie, D.1    Hua, F.2    Homandberg, G.A.3
  • 49
    • 0027367049 scopus 로고
    • Cartilage chondrolysis by fibronectin fragments is associated with release of several proteinases: Stromelysin plays a major role in chondrolysis
    • D Xie F Hui GA Homandberg 1994 Cartilage chondrolysis by fibronectin fragments is associated with release of several proteinases: stromelysin plays a major role in chondrolysis Arch Biochem Biophys 307 1 110 118
    • (1994) Arch Biochem Biophys , vol.307 , Issue.1 , pp. 110-118
    • Xie, D.1    Hui, F.2    Homandberg, G.A.3
  • 50
    • 33747203514 scopus 로고    scopus 로고
    • Cartilage destruction by matrix degradation products
    • T Yasuda 2006 Cartilage destruction by matrix degradation products Mod Rheumatol 16 197 205
    • (2006) Mod Rheumatol , vol.16 , pp. 197-205
    • Yasuda, T.1
  • 51
    • 35348823017 scopus 로고    scopus 로고
    • Inhibition of nuclear factor-κB by hyaluronan in rheumatoid chondrocytes stimulated with COOH-terminal heparin-binding fibronectin fragment
    • T Yasuda T Nakamura 2007 Inhibition of nuclear factor-κB by hyaluronan in rheumatoid chondrocytes stimulated with COOH-terminal heparin-binding fibronectin fragment Mod Rheumatol 17 5 391 397
    • (2007) Mod Rheumatol , vol.17 , Issue.5 , pp. 391-397
    • Yasuda, T.1    Nakamura, T.2
  • 52
    • 0036161629 scopus 로고    scopus 로고
    • A fibronectin fragment induces type II collagen degradation by collagenase through an interleukin-1-mediated pathway
    • T Yasuda AR Poole 2002 A fibronectin fragment induces type II collagen degradation by collagenase through an interleukin-1-mediated pathway Arthritis Rheum 46 138 148
    • (2002) Arthritis Rheum , vol.46 , pp. 138-148
    • Yasuda, T.1    Poole, A.R.2
  • 53
    • 0038667483 scopus 로고    scopus 로고
    • Involvement of CD44 in induction of matrix metalloproteinases by a COOH-terminal heparin-binding fragment of fibronectin in human articular cartilage in culture
    • T Yasuda RA Poole M Shimizu T Nakagawa SM Julovi H Tamamura N Fujii T Nakamura 2003 Involvement of CD44 in induction of matrix metalloproteinases by a COOH-terminal heparin-binding fragment of fibronectin in human articular cartilage in culture Arthritis Rheum 48 5 1271 1280
    • (2003) Arthritis Rheum , vol.48 , Issue.5 , pp. 1271-1280
    • Yasuda, T.1    Poole, R.A.2    Shimizu, M.3    Nakagawa, T.4    Julovi, S.M.5    Tamamura, H.6    Fujii, N.7    Nakamura, T.8
  • 54
    • 4544300871 scopus 로고    scopus 로고
    • COOH-terminal heparin-binding fibronectin fragment induces nitric oxide production in rheumatoid cartilage through CD44
    • T Yasuda T Kakinuma SM Julovi M Yoshida T Hiramitsu M Akiyoshi T Nakamura 2004 COOH-terminal heparin-binding fibronectin fragment induces nitric oxide production in rheumatoid cartilage through CD44 Rheumatology 43 1116 1120
    • (2004) Rheumatology , vol.43 , pp. 1116-1120
    • Yasuda, T.1    Kakinuma, T.2    Julovi, S.M.3    Yoshida, M.4    Hiramitsu, T.5    Akiyoshi, M.6    Nakamura, T.7
  • 55
    • 0142260971 scopus 로고    scopus 로고
    • FN metabolism of cartilage explants in response to the frequency of intermittent loading
    • A Wolf RX Raiss J Steinmeyer 2003 FN metabolism of cartilage explants in response to the frequency of intermittent loading J Orthop Res 21 1081 1089
    • (2003) J Orthop Res , vol.21 , pp. 1081-1089
    • Wolf, A.1    Raiss, R.X.2    Steinmeyer, J.3


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