Induction of mitotic arrest and apoptosis by a novel synthetic quinolone analogue, CWC-8, via intrinsic and extrinsic apoptotic pathways in human osteogenic sarcoma U-2 OS cells

Anticancer Research

Volumn 29, Issue 8, 2009, Pages 3139-3148

  Chang, Yu Hsun ^a   Yang, Jai Sing ^a   Kuo, Sheng Chu ^a   Chung, Jing Gung ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; CWC 8; Human osteogenic sarcoma U 2 OS cells; Mitotic arrest

Indexed keywords

6 (NAPHTHALEN 1 YL)[1,3]DIOXOLO[4,5 G]QUINOLIN 8(5H) ONE; CWC 8; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL VIABILITY; CHLORINATION; CONTROLLED STUDY; CYCLIZATION; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; MITOSIS INHIBITION; OSTEOSARCOMA; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; BONE NEOPLASMS; CASPASES; CDC2 PROTEIN KINASE; CELL CYCLE; DIOXOLES; HUMANS; MITOSIS; OSTEOSARCOMA; QUINOLONES; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 68549097938     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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