NCI-Sponsored trial for the evaluation of safety and preliminary efficacy of 3′-Deoxy-3′-[18F]fluorothymidine (FLT) as a marker of proliferation in patients with recurrent gliomas: Preliminary efficacy studies

Molecular Imaging and Biology

Volumn 11, Issue 5, 2009, Pages 343-355

  Spence, Alexander M ^a   Muzi, Mark ^b   Link, Jeanne M ^b   O'Sullivan, Finbarr ^c   Eary, Janet F ^b   Hoffman, John M ^d   Shankar, Lalitha K ^e   Krohn, Kenneth A ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY COLLEGE CORK   (Ireland)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

3 18F fluoro 3 deoxythymidine; FLT; Fluorothymidine; Glioma; Positron emission tomography (PET); Proliferation imaging; Radionecrosis

Indexed keywords

3' FLUOROTHYMIDINE F 18; FLUORODEOXYGLUCOSE F 18;

ADULT; ARTICLE; ASTROCYTOMA; BLOOD BRAIN BARRIER; BLOOD SAMPLING; CANCER RECURRENCE; CELL PROLIFERATION; CLINICAL ARTICLE; COMPARTMENT MODEL; CONTRAST ENHANCEMENT; DRUG METABOLISM; DRUG PENETRATION; DRUG TRANSPORT; DRUG UPTAKE; FEMALE; GLIOBLASTOMA; GLIOMA; GLIOSARCOMA; HUMAN; IMAGE ANALYSIS; IMAGE ENHANCEMENT; IMAGE QUALITY; ISOTOPE LABELING; MALE; MOLECULAR IMAGING; OLIGODENDROGLIOMA; PATIENT SAFETY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIATION NECROSIS;

ADULT; BRAIN CHEMISTRY; BRAIN NEOPLASMS; CELL GROWTH PROCESSES; DIAGNOSIS, DIFFERENTIAL; DIDEOXYNUCLEOSIDES; FEMALE; GLIOMA; HUMANS; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; NECROSIS; NEOPLASM RECURRENCE, LOCAL; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; STATISTICS, NONPARAMETRIC; YOUNG ADULT;

EID: 68449095057     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-009-0215-2     Document Type: Article

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