Design and synthesis of (2R,3S)-iodoreboxetine analogues for SPECT imaging of the noradrenaline transporter

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 17, 2009, Pages 4996-4998

  Jobson, Nicola K ^a   Crawford, Andrew R ^a   Dewar, Deborah ^a   Pimlott, Sally L ^a   Sutherland, Andrew ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Imaging; Noradrenaline transporter; Reboxetine; SPECT; Stereoselective synthesis

Indexed keywords

DOPAMINE TRANSPORTER; NORADRENALIN TRANSPORTER; REBOXETINE; SEROTONIN TRANSPORTER;

ARTICLE; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STEREOCHEMISTRY;

DRUG DESIGN; IODINE RADIOISOTOPES; MORPHOLINES; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; RADIOPHARMACEUTICALS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 68349158660     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.07.064     Document Type: Article

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