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Volumn 6, Issue 6, 2009, Pages 29-37

Should psychiatrists use atypical antipsychotics to treat nonpsychotic anxiety?

Author keywords

Anxiety disorder; Atypical antipsychotic; Extrapyramidal side effects; Generalized anxiety disorder; Neuroleptic malignant syndrome; Obsessive compulsive disorder; Off label; Posttraumatic stress disorder; Social anxiety disorder; Tardive dyskinesia

Indexed keywords

4 AMINOBUTYRIC ACID; AMITRIPTYLINE PLUS PERPHENAZINE; ARIPIPRAZOLE; ATYPICAL ANTIPSYCHOTIC AGENT; DOPAMINE 2 RECEPTOR; OLANZAPINE; QUETIAPINE; RISPERIDONE; TRIFLUOPERAZINE;

EID: 68349128598     PISSN: 15505952     EISSN: 15555194     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (26)

References (51)
  • 1
    • 54949154218 scopus 로고    scopus 로고
    • World Federation of Society of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders - first revision
    • Bandelow B, Zohar J, Hollander E, et al. World Federation of Society of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders - first revision. World J Biol Psychiatry. 2008;9:248-312.
    • (2008) World J Biol Psychiatry , vol.9 , pp. 248-312
    • Bandelow, B.1    Zohar, J.2    Hollander, E.3
  • 2
    • 33750063164 scopus 로고    scopus 로고
    • Efficacy of typical and atypical antipsychotics for primary and comorbid anxiety symptoms or disorders: A review
    • Gao K, Muzina D, Gajwani P, Calabrese JR. Efficacy of typical and atypical antipsychotics for primary and comorbid anxiety symptoms or disorders: a review. J Clin Psychiatry. 2006;67:1327-1340.
    • (2006) J Clin Psychiatry , vol.67 , pp. 1327-1340
    • Gao, K.1    Muzina, D.2    Gajwani, P.3    Calabrese, J.R.4
  • 3
    • 0022610150 scopus 로고
    • Effective short-term treatment of generalized anxiety disorder with trifluoperazine
    • Mendels J, Krajewski TF, Huffer V, et al. Effective short-term treatment of generalized anxiety disorder with trifluoperazine. J Clin Psychiatry. 1986;47:170-174.
    • (1986) J Clin Psychiatry , vol.47 , pp. 170-174
    • Mendels, J.1    Krajewski, T.F.2    Huffer, V.3
  • 4
    • 68349156084 scopus 로고    scopus 로고
    • Stelazine [package insert, Collegeville, PA: GlaxoSmithKline; 2001. Available at:, Accessed April 14, 2009
    • Stelazine [package insert]. Collegeville, PA: GlaxoSmithKline; 2001. Available at: http://www.fda.gov/cder/foi/label/2001/11552s112lbl.PDF. Accessed April 14, 2009.
  • 5
    • 68349148603 scopus 로고    scopus 로고
    • Brawman-Mintzer O, Nietert PJ, Rynn M, et al. Quetiapine monotherapy in patients with GAD. In the New Research Abstract of the 159th Annual Meeting of American Psychiatric Association, Toronto, Canada, May 20-25, 2006. NR: 634.
    • Brawman-Mintzer O, Nietert PJ, Rynn M, et al. Quetiapine monotherapy in patients with GAD. In the New Research Abstract of the 159th Annual Meeting of American Psychiatric Association, Toronto, Canada, May 20-25, 2006. NR: 634.
  • 6
    • 68349139963 scopus 로고    scopus 로고
    • Chouinard G, Bandelow B, Ahokas A, et al. Once-daily extended release quetiapine fumarate (Quetiapine XR) monotherapy in generalized anxiety disorder: a phase III, double-blind, placebo-controlled study. In the Abstract Viewer of the 46th American College of Neuropsychopharmacology Annual Meeting, Boca Raton, Florida, USA. December 9-13, 2007:25.
    • Chouinard G, Bandelow B, Ahokas A, et al. Once-daily extended release quetiapine fumarate (Quetiapine XR) monotherapy in generalized anxiety disorder: a phase III, double-blind, placebo-controlled study. In the Abstract Viewer of the 46th American College of Neuropsychopharmacology Annual Meeting, Boca Raton, Florida, USA. December 9-13, 2007:25.
  • 7
    • 68349159203 scopus 로고    scopus 로고
    • Joyce M, Khan A, Atkinson S, et al. Efficacy and safety of extended release quetiapine fumarate (quetiapine XR) monotherapy in patients with generalized anxiety disorder (GAD). In the New Research Abstract of the 159th Annual Meeting of American Psychiatric Association, Washington DC, USA, May 3-8, 2008. NR:3138.
    • Joyce M, Khan A, Atkinson S, et al. Efficacy and safety of extended release quetiapine fumarate (quetiapine XR) monotherapy in patients with generalized anxiety disorder (GAD). In the New Research Abstract of the 159th Annual Meeting of American Psychiatric Association, Washington DC, USA, May 3-8, 2008. NR:3138.
  • 8
    • 68349143181 scopus 로고    scopus 로고
    • Katzman M, Brawman-Mintzer O, Reyes E, et al. Extended release quetiapine fumarate (quetiapine XR) monotherapy in maintenance treatment of generalized anxiety disorder (GAD): efficacy and tolerability results from a randomized, placebo-controlled trial. In the New Research Abstract of the 159th Annual Meeting of American Psychiatric Association, Washington DC, USA, May 3-8, 2008. NR:3140.
    • Katzman M, Brawman-Mintzer O, Reyes E, et al. Extended release quetiapine fumarate (quetiapine XR) monotherapy in maintenance treatment of generalized anxiety disorder (GAD): efficacy and tolerability results from a randomized, placebo-controlled trial. In the New Research Abstract of the 159th Annual Meeting of American Psychiatric Association, Washington DC, USA, May 3-8, 2008. NR:3140.
  • 9
    • 68349148604 scopus 로고    scopus 로고
    • Tefera L, Tomao LC. Anxiety. eMedicine Emergency Medicine. 2008 Nov 20. Available at: http://emedicine.medscape.com/article/805265-overview. Accessed April 14, 2009.
    • Tefera L, Tomao LC. Anxiety. eMedicine Emergency Medicine. 2008 Nov 20. Available at: http://emedicine.medscape.com/article/805265-overview. Accessed April 14, 2009.
  • 10
    • 0002345644 scopus 로고    scopus 로고
    • Neurobiological basis of anxiety disorders
    • Davis KL, Charney D, Coyle JT, Nemeroff C eds, Philadelphia: Lippincott Williams & Wilkins;
    • Charney DS, Drevets WC. Neurobiological basis of anxiety disorders. In: Davis KL, Charney D, Coyle JT, Nemeroff C (eds). Neuropsychopharmacology: The Fifth Generation of Progress. Philadelphia: Lippincott Williams & Wilkins; 2002:901-930.
    • (2002) Neuropsychopharmacology: The Fifth Generation of Progress , pp. 901-930
    • Charney, D.S.1    Drevets, W.C.2
  • 11
    • 4644336231 scopus 로고    scopus 로고
    • The Role of GABA in the pathophysiology and treatment of anxiety disorders
    • Nemeroff CB. The Role of GABA in the pathophysiology and treatment of anxiety disorders. Psychopharmacol Bull. 2003;37:133-146.
    • (2003) Psychopharmacol Bull , vol.37 , pp. 133-146
    • Nemeroff, C.B.1
  • 12
    • 0031018537 scopus 로고    scopus 로고
    • Dopamine reuptake site densities in patients with social phobia
    • Tiihonen J, Kuikka J, Bergström K, et al. Dopamine reuptake site densities in patients with social phobia. Am J Psychiatry. 1997;154:239-242.
    • (1997) Am J Psychiatry , vol.154 , pp. 239-242
    • Tiihonen, J.1    Kuikka, J.2    Bergström, K.3
  • 13
    • 58549108041 scopus 로고    scopus 로고
    • The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans, compared with controls
    • Voisey J, Swagell CD, Hughes IP, et al. The DRD2 gene 957C>T polymorphism is associated with posttraumatic stress disorder in war veterans, compared with controls. Depress Anxiety. 2009;26:28-33.
    • (2009) Depress Anxiety , vol.26 , pp. 28-33
    • Voisey, J.1    Swagell, C.D.2    Hughes, I.P.3
  • 14
    • 0034077277 scopus 로고    scopus 로고
    • Clozapine inhibits synaptic transmission at GABAergic synapses established by ventral tegmental area neurones in culture
    • Michel FJ, Trudeau LE. Clozapine inhibits synaptic transmission at GABAergic synapses established by ventral tegmental area neurones in culture. Neuropharmacology. 2000;39:1536-1543.
    • (2000) Neuropharmacology , vol.39 , pp. 1536-1543
    • Michel, F.J.1    Trudeau, L.E.2
  • 15
    • 43849098918 scopus 로고    scopus 로고
    • Olanzapine counteracts stress-induced anxiety-like behavior in rats
    • Locchi F, Dall'olio R, Gandolfi O, Rimondini R. Olanzapine counteracts stress-induced anxiety-like behavior in rats. Neurosci Lett. 2008;438:146-149.
    • (2008) Neurosci Lett , vol.438 , pp. 146-149
    • Locchi, F.1    Dall'olio, R.2    Gandolfi, O.3    Rimondini, R.4
  • 16
    • 0034091239 scopus 로고    scopus 로고
    • A positron emission tomography study of quetiapine in schizophrenia: A preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy
    • Kapur S, Zipursky R, Jones C, et al. A positron emission tomography study of quetiapine in schizophrenia: a preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy. Arch Gen Psychiatry. 2000;57:553-559.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 553-559
    • Kapur, S.1    Zipursky, R.2    Jones, C.3
  • 17
    • 39649112850 scopus 로고    scopus 로고
    • Histaminergic system of the lateral septum in the modulation of anxiety-like behaviour in rats
    • Zarrindast MR, Valizadegan F, Rostami P, Rezayof A. Histaminergic system of the lateral septum in the modulation of anxiety-like behaviour in rats. Eur J Pharmacol. 2008;583:108-114.
    • (2008) Eur J Pharmacol , vol.583 , pp. 108-114
    • Zarrindast, M.R.1    Valizadegan, F.2    Rostami, P.3    Rezayof, A.4
  • 20
    • 60349130186 scopus 로고    scopus 로고
    • Adjunctive aripiprazole in major depressive disorder: Analysis of efficacy and safety in patients with anxious and atypical features
    • Trivedi MH, Thase ME, Fava M, et al. Adjunctive aripiprazole in major depressive disorder: analysis of efficacy and safety in patients with anxious and atypical features. J Clin Psychiatry. 2008;69:1928-1936.
    • (2008) J Clin Psychiatry , vol.69 , pp. 1928-1936
    • Trivedi, M.H.1    Thase, M.E.2    Fava, M.3
  • 21
    • 41849148995 scopus 로고    scopus 로고
    • Quetiapine augmentation of paroxetine CR for the treatment of refractory generalized anxiety disorder: Preliminary findings
    • Simon NM, Connor KM, LeBeau RT, et al. Quetiapine augmentation of paroxetine CR for the treatment of refractory generalized anxiety disorder: preliminary findings. Psychopharmacology (Berl). 2008;197:675-681.
    • (2008) Psychopharmacology (Berl) , vol.197 , pp. 675-681
    • Simon, N.M.1    Connor, K.M.2    LeBeau, R.T.3
  • 22
    • 68349146747 scopus 로고    scopus 로고
    • Efficacy and tolerability of extended release quetiapine fumarate (quetiapine XR) monotherapy in the treatment of generalized anxiety disorder
    • Merideth C, Cutler A, Neijber A, et al. Efficacy and tolerability of extended release quetiapine fumarate (quetiapine XR) monotherapy in the treatment of generalized anxiety disorder. Eur Neuropsychopharmacol. 2008;18:S499-S500.
    • (2008) Eur Neuropsychopharmacol , vol.18
    • Merideth, C.1    Cutler, A.2    Neijber, A.3
  • 23
    • 32144450616 scopus 로고    scopus 로고
    • Olanzapine augmentation of fluoxetine for refractory generalized anxiety disorder: A placebo controlled study
    • Pollack MH, Simon NM, Zalta AK, et al. Olanzapine augmentation of fluoxetine for refractory generalized anxiety disorder: a placebo controlled study. Biol Psychiatry. 2006;59:211-215.
    • (2006) Biol Psychiatry , vol.59 , pp. 211-215
    • Pollack, M.H.1    Simon, N.M.2    Zalta, A.K.3
  • 24
    • 27544471383 scopus 로고    scopus 로고
    • Adjunctive risperidone in generalized anxiety disorder: A double-blind, placebo-controlled study
    • Brawman-Mintzer O, Knapp RG, Nietert PJ. Adjunctive risperidone in generalized anxiety disorder: a double-blind, placebo-controlled study. J Clin Psychiatry. 2005;66:1321-1325.
    • (2005) J Clin Psychiatry , vol.66 , pp. 1321-1325
    • Brawman-Mintzer, O.1    Knapp, R.G.2    Nietert, P.J.3
  • 25
    • 61849136054 scopus 로고    scopus 로고
    • Adjunctive risperidone in the treatment of generalized anxiety disorder: A double-blind, prospective, placebo-controlled, randomized trial
    • Pandina GJ, Canuso CM, Turkoz I, et al. Adjunctive risperidone in the treatment of generalized anxiety disorder: a double-blind, prospective, placebo-controlled, randomized trial. Psychopharmacol Bull. 2007;40(3):41-57.
    • (2007) Psychopharmacol Bull , vol.40 , Issue.3 , pp. 41-57
    • Pandina, G.J.1    Canuso, C.M.2    Turkoz, I.3
  • 26
    • 68349128922 scopus 로고    scopus 로고
    • Sheehan DV, McElroy SL, Harnett-Sheehan K, et al. Randomized, placebo-controlled trial of risperidone for acute treatment of bipolar anxiety. J Affect Disorder. In press.
    • Sheehan DV, McElroy SL, Harnett-Sheehan K, et al. Randomized, placebo-controlled trial of risperidone for acute treatment of bipolar anxiety. J Affect Disorder. In press.
  • 27
    • 1542617053 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of olanzapine addition in fluoxetine-refractory obsessive-compulsive disorder
    • Shapira NA, Ward HE, Mandoki M, et al. A double-blind, placebo-controlled trial of olanzapine addition in fluoxetine-refractory obsessive-compulsive disorder. Biol Psychiatry. 2004;55:553-555.
    • (2004) Biol Psychiatry , vol.55 , pp. 553-555
    • Shapira, N.A.1    Ward, H.E.2    Mandoki, M.3
  • 28
    • 2442562322 scopus 로고    scopus 로고
    • Augmentation of serotonin reuptake inhibitors in refractory obsessive-compulsive disorder using adjunctive olanzapine: A placebo-controlled trial
    • Bystritsky A, Ackerman DL, Rosen RM, et al. Augmentation of serotonin reuptake inhibitors in refractory obsessive-compulsive disorder using adjunctive olanzapine: a placebo-controlled trial. J Clin Psychiatry. 2004;65:565-568.
    • (2004) J Clin Psychiatry , vol.65 , pp. 565-568
    • Bystritsky, A.1    Ackerman, D.L.2    Rosen, R.M.3
  • 29
    • 4544252050 scopus 로고    scopus 로고
    • A double-blind, randomized, placebo-controlled trial of quetiapine addition in patients with obsessive-compulsive disorder refractory to serotonin reuptake inhibitors
    • Denys D, de Geus F, van Megen HJ, Westenberg HG. A double-blind, randomized, placebo-controlled trial of quetiapine addition in patients with obsessive-compulsive disorder refractory to serotonin reuptake inhibitors. J Clin Psychiatry. 2004;65:1040-1048.
    • (2004) J Clin Psychiatry , vol.65 , pp. 1040-1048
    • Denys, D.1    de Geus, F.2    van Megen, H.J.3    Westenberg, H.G.4
  • 30
    • 26844543672 scopus 로고    scopus 로고
    • Quetiapine augmentation of SRIs in treatment refractory obsessive-compulsive disorder: A double-blind, randomised, placebo-controlled study
    • Jan 24;
    • Carey PD, Vythilingum B, Seedat S, et al. Quetiapine augmentation of SRIs in treatment refractory obsessive-compulsive disorder: a double-blind, randomised, placebo-controlled study. BMC Psychiatry. 2005 Jan 24;5:5.
    • (2005) BMC Psychiatry , vol.5 , pp. 5
    • Carey, P.D.1    Vythilingum, B.2    Seedat, S.3
  • 31
    • 0033846191 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of risperidone addition in serotonin reuptake inhibitor-refractory obsessive-compulsive disorder
    • McDougle CJ, Epperson CN, Pelton GH, et al. A double-blind, placebo-controlled study of risperidone addition in serotonin reuptake inhibitor-refractory obsessive-compulsive disorder. Arch Gen Psychiatry. 2000;57:794-801.
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 794-801
    • McDougle, C.J.1    Epperson, C.N.2    Pelton, G.H.3
  • 32
    • 0742270813 scopus 로고    scopus 로고
    • Risperidone augmentation in treatment-resistant obsessive-compulsive disorder: A double-blind, placebo-controlled study
    • Hollander E, Baldini Rossi N, Sood E, Pallanti S. Risperidone augmentation in treatment-resistant obsessive-compulsive disorder: a double-blind, placebo-controlled study. Int J Neuropsychopharmacol. 2003;6:397-401.
    • (2003) Int J Neuropsychopharmacol , vol.6 , pp. 397-401
    • Hollander, E.1    Baldini Rossi, N.2    Sood, E.3    Pallanti, S.4
  • 33
    • 21744462907 scopus 로고    scopus 로고
    • Risperidone and haloperidol augmentation of serotonin reuptake inhibitors in refractory obsessive-compulsive disorder: A crossover study
    • Li X, May RS, Tolbert LC, et al. Risperidone and haloperidol augmentation of serotonin reuptake inhibitors in refractory obsessive-compulsive disorder: a crossover study. J Clin Psychiatry. 2005;66:736-743.
    • (2005) J Clin Psychiatry , vol.66 , pp. 736-743
    • Li, X.1    May, R.S.2    Tolbert, L.C.3
  • 34
    • 9644302676 scopus 로고    scopus 로고
    • Low-dose risperidone augmentation of fluvoxamine treatment in obsessive-compulsive disorder: A double-blind, placebo-controlled study
    • Erzegovesi S, Guglielmo E, Siliprandi F, Bellodi L. Low-dose risperidone augmentation of fluvoxamine treatment in obsessive-compulsive disorder: a double-blind, placebo-controlled study. Eur Neuropsychopharmacol. 2005;15:69-74.
    • (2005) Eur Neuropsychopharmacol , vol.15 , pp. 69-74
    • Erzegovesi, S.1    Guglielmo, E.2    Siliprandi, F.3    Bellodi, L.4
  • 35
    • 0034956343 scopus 로고    scopus 로고
    • Olanzapine in the treatment of post-traumatic stress disorder: A pilot study
    • Butterfield MI, Becker ME, Connor KM, et al. Olanzapine in the treatment of post-traumatic stress disorder: a pilot study. Int Clin Psychopharmacol. 2001;16:197-203.
    • (2001) Int Clin Psychopharmacol , vol.16 , pp. 197-203
    • Butterfield, M.I.1    Becker, M.E.2    Connor, K.M.3
  • 36
    • 0036789143 scopus 로고    scopus 로고
    • Adjunctive olanzapine for SSRI-resistant combat-related PTSD: A double-blind, placebo-controlled study
    • Stein MB, Kline NA, Matloff JL. Adjunctive olanzapine for SSRI-resistant combat-related PTSD: a double-blind, placebo-controlled study. Am J Psychiatry. 2002;159:1777-1779.
    • (2002) Am J Psychiatry , vol.159 , pp. 1777-1779
    • Stein, M.B.1    Kline, N.A.2    Matloff, J.L.3
  • 37
    • 0037239124 scopus 로고    scopus 로고
    • Adjunctive risperidone treatment in post-traumatic stress disorder: A preliminary controlled trial of effects on comorbid psychotic symptoms
    • Hamner MB, Faldowski RA, Ulmer HG, et al. Adjunctive risperidone treatment in post-traumatic stress disorder: a preliminary controlled trial of effects on comorbid psychotic symptoms. Int Clin Psychopharmacol. 2003;18:1-8.
    • (2003) Int Clin Psychopharmacol , vol.18 , pp. 1-8
    • Hamner, M.B.1    Faldowski, R.A.2    Ulmer, H.G.3
  • 38
    • 14644423248 scopus 로고    scopus 로고
    • Adjunctive risperidone in the treatment of chronic combat-related posttraumatic stress disorder
    • Bartzokis G, Lu PH, Turner J, et al. Adjunctive risperidone in the treatment of chronic combat-related posttraumatic stress disorder. Biol Psychiatry. 2005;57:474-479.
    • (2005) Biol Psychiatry , vol.57 , pp. 474-479
    • Bartzokis, G.1    Lu, P.H.2    Turner, J.3
  • 39
    • 33746686967 scopus 로고    scopus 로고
    • Risperidone monotherapy for post-traumatic stress disorder related to sexual assault and domestic abuse in women
    • Padala PR, Madison J, Monnahan M, et al. Risperidone monotherapy for post-traumatic stress disorder related to sexual assault and domestic abuse in women. Int Clin Psychopharmacol. 2006;21:275-280.
    • (2006) Int Clin Psychopharmacol , vol.21 , pp. 275-280
    • Padala, P.R.1    Madison, J.2    Monnahan, M.3
  • 40
    • 0036902244 scopus 로고    scopus 로고
    • Efficacy of olanzapine in social anxiety disorder: A pilot study
    • Barnett SD, Kramer ML, Casat CD, et al. Efficacy of olanzapine in social anxiety disorder: a pilot study. J Psychopharmacol. 2002;16:365-368.
    • (2002) J Psychopharmacol , vol.16 , pp. 365-368
    • Barnett, S.D.1    Kramer, M.L.2    Casat, C.D.3
  • 41
    • 34548137738 scopus 로고    scopus 로고
    • Quetiapine as monotherapy for social anxiety disorder: A placebo-controlled study
    • Vaishnavi S, Alamy S, Zhang W, et al. Quetiapine as monotherapy for social anxiety disorder: a placebo-controlled study. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31:1464-1469.
    • (2007) Prog Neuropsychopharmacol Biol Psychiatry , vol.31 , pp. 1464-1469
    • Vaishnavi, S.1    Alamy, S.2    Zhang, W.3
  • 42
    • 68349125807 scopus 로고    scopus 로고
    • Off-label use of atypical antipsychotics linked to increased mortality in elderly
    • April 12. Available at:, Accessed April 14, 2009
    • Waknine Y. Off-label use of atypical antipsychotics linked to increased mortality in elderly. Medscape Alert. 2005 April 12. Available at: http://www.medscape.com/viewarticle/502902. Accessed April 14, 2009.
    • (2005) Medscape Alert
    • Waknine, Y.1
  • 43
    • 68349132004 scopus 로고    scopus 로고
    • Prescribing atypical antipsychotics: What are the risks? The Carlat Psychiatry Report
    • Posternak M. Prescribing atypical antipsychotics: what are the risks? The Carlat Psychiatry Report. 2009;7:3-8.
    • (2009) , vol.7 , pp. 3-8
    • Posternak, M.1
  • 44
    • 1542373740 scopus 로고    scopus 로고
    • Lower risk for tardive dyskinesia associated with second-generation antipsychotics: A systematic review of 1-year studies
    • Correll CU, Leucht S, Kane JM. Lower risk for tardive dyskinesia associated with second-generation antipsychotics: a systematic review of 1-year studies. Am J Psychiatry. 2004;161:414-425.
    • (2004) Am J Psychiatry , vol.161 , pp. 414-425
    • Correll, C.U.1    Leucht, S.2    Kane, J.M.3
  • 45
    • 40949136198 scopus 로고    scopus 로고
    • Antipsychotic-induced extrapyramidal side effects in bipolar disorder and schizophrenia: A systematic review
    • Gao K, Kemp DE, Ganocy SJ, et al. Antipsychotic-induced extrapyramidal side effects in bipolar disorder and schizophrenia: a systematic review. J Clin Psychopharmacol. 2008;28:203-209.
    • (2008) J Clin Psychopharmacol , vol.28 , pp. 203-209
    • Gao, K.1    Kemp, D.E.2    Ganocy, S.J.3
  • 46
    • 18744366088 scopus 로고    scopus 로고
    • Second-generation (atypical) antipsychotics and metabolic effects: A comprehensive literature review
    • Newcomer JW. Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. CNS Drugs. 2005;19 Suppl 1:1-93.
    • (2005) CNS Drugs , vol.19 , Issue.SUPPL. 1 , pp. 1-93
    • Newcomer, J.W.1
  • 47
    • 43049125770 scopus 로고    scopus 로고
    • Metabolic syndrome in first episode schizophrenia - a randomized double-blind controlled, short-term prospective study
    • Saddichha S, Manjunatha N, Ameen S, Akhtar S. Metabolic syndrome in first episode schizophrenia - a randomized double-blind controlled, short-term prospective study. Schizophr Res. 2008;101(1-3):266-272.
    • (2008) Schizophr Res , vol.101 , Issue.1-3 , pp. 266-272
    • Saddichha, S.1    Manjunatha, N.2    Ameen, S.3    Akhtar, S.4
  • 48
    • 58349114259 scopus 로고    scopus 로고
    • Atypical antipsychotic drugs and the risk of sudden cardiac death
    • Ray WA, Chung CP, Murray KT, et al. Atypical antipsychotic drugs and the risk of sudden cardiac death. N Engl J Med. 2009;36:225-235.
    • (2009) N Engl J Med , vol.36 , pp. 225-235
    • Ray, W.A.1    Chung, C.P.2    Murray, K.T.3
  • 49
    • 28844501994 scopus 로고    scopus 로고
    • QTc interval measurement and metabolic parameters in psychiatric patients taking typical or atypical antipsychotic drugs: A preliminary study
    • Mackin P, Young AH. QTc interval measurement and metabolic parameters in psychiatric patients taking typical or atypical antipsychotic drugs: a preliminary study. J Clin Psychiatry. 2005;66:1386-1391.
    • (2005) J Clin Psychiatry , vol.66 , pp. 1386-1391
    • Mackin, P.1    Young, A.H.2
  • 50
    • 36849026757 scopus 로고    scopus 로고
    • Abuse of olanzapine by substance abusers
    • Reeves RR. Abuse of olanzapine by substance abusers. J Psychoactive Drugs. 2007;39:297-299.
    • (2007) J Psychoactive Drugs , vol.39 , pp. 297-299
    • Reeves, R.R.1


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