Alteration of transcriptional profile in human bronchial epithelial cells induced by cigarette smoke condensate

Toxicology Letters

Volumn 190, Issue 1, 2009, Pages 23-31

  Hu, Ying Chun ^a   Yang, Zhi Hua ^a   Zhong, Ke Jun ^b   Niu, Li Jing ^c   Pan, Xiu Jie ^a   Wu, De Chang ^a   Sun, Xian Jun ^b   Zhou, Ping Kun ^a   Zhu, Mao Xiang ^a   Huo, Yan Ying ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b China Tobacco Hunan Industrial Co Ltd   (China)

^c CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Bronchial epithelial cells; Cigarette smoke condensate; Transcriptional profile; Transformation

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; H19 PROTEIN; MEG3 PROTEIN; NDN PROTEIN; SOMATOMEDIN B; TOBACCO SMOKE; TUMOR MARKER; UNCLASSIFIED DRUG;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL EXPERIMENT; ARTICLE; CARCINOGENICITY; CELL DIFFERENTIATION; CELL GROWTH; CIGARETTE SMOKING; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LUNG CARCINOGENESIS; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTOMICS; UNINDEXED SEQUENCE; UPREGULATION;

ANIMALS; AZACITIDINE; BLOTTING, NORTHERN; BRONCHI; CELL DIFFERENTIATION; CELL LINE; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL CELLS; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HUMANS; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOBACCO; TRANSCRIPTION, GENETIC;

MUS MUSCULUS; PAPILLOMAVIRIDAE;

EID: 68349128506     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.06.860     Document Type: Article

References (42)

1. Beer D.G., et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat. Med. 8 8 (2002) 816-824
2. Benetatos L., et al. Promoter hypermethylation of the MEG3 (DLK1/MEG3) imprinted gene in multiple myeloma. Clin. Lymphoma Myeloma 8 3 (2008) 171-175
3. Bhattacharjee A., et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc. Natl. Acad. Sci. U.S.A. 98 24 (2001) 13790-13795
4. Ezzati M., and Lopez A.D. Estimates of global mortality attributable to smoking in 2000. Lancet 362 9387 (2003) 847-852
5. Franklin W.A., et al. Widely dispersed p53 mutation in respiratory epithelium A novel mechanism for field carcinogenesis. J. Clin. Invest. 100 8 (1997) 2133-2137
6. Gandini S., et al. Tobacco smoking and cancer: a meta-analysis. Int. J. Cancer 122 1 (2008) 155-164
7. Garber M.E., et al. Diversity of gene expression in adenocarcinoma of the lung. Proc. Natl. Acad. Sci. U.S.A. 98 24 (2001) 13784-13789
8. Garcia M., et al. Global Cancer Facts & Figures 2007 (2007), American Cancer Society, Atlanta, GA
9. Golubkov V.S., et al. Membrane type-1 matrix metalloproteinase confers aneuploidy and tumorigenicity on mammary epithelial cells. Cancer Res. 66 21 (2006) 10460-10465
10. Guo M., et al. Promoter hypermethylation of resected bronchial margins: a field defect of changes?. Clin. Cancer Res. 10 15 (2004) 5131-5136
11. Hahn F.F., et al. A review of the histopathology of cigarette smoke-induced lung cancer in rats and mice. Int. J. Toxicol. 26 4 (2007) 307-313
12. Hasegawa K., and Yoshikawa K. Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons. J. Neurosci. 28 35 (2008) 8772-8784
13. Hecht S.S. Carcinogenicity studies of inhaled cigarette smoke in laboratory animals: old and new. Carcinogenesis 26 9 (2005) 1488-1492
14. Hei T.K., et al. Malignant transformation of human bronchial epithelial cells by radon-simulated alpha-particles. Carcinogenesis 15 3 (1994) 431-437
15. Hei T.K., Wu L.J., and Piao C.Q. Malignant transformation of immortalized human bronchial epithelial cells by asbestos fibers. Environ. Health Perspect. 105 Suppl. 5 (1997) 1085-1088
16. Herman J.G., and Baylin S.B. Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 349 21 (2003) 2042-2054
17. Herman J.G., et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc. Natl. Acad. Sci. U.S.A. 95 12 (1998) 6870-6875
18. Hoffmann D., Hoffmann I., and El-Bayoumy K. The less harmful cigarette: a controversial issue. Atribute to Ernst L. Wynder. Chem. Res. Toxicol. 14 7 (2001) 767-790
19. Jeanmart M., et al. Value of immunohistochemical markers in preinvasive bronchial lesions in risk assessment of lung cancer. Clin. Cancer Res. 9 6 (2003) 2195-2203
20. Kohda M., et al. Frequent loss of imprinting of IGF2 and MEST in lung adenocarcinoma. Mol. Carcinog. 31 4 (2001) 184-191
21. Langenfeld J., et al. Inhibited transformation of immortalized human bronchial epithelial cells by retinoic acid is linked to cyclin E down-regulation. Oncogene 13 9 (1996) 1983-1990
22. Lecomte J., and Mercier C. The WHO atlas on global resources for persons with intellectual disabilities: a right to health perspective. Salud Publica Mex 50 Suppl. 2 (2008) ps160-ps166
23. Levin M.L., Goldstein H., and Gerhardt P.R. Cancer and tobacco smoking; a preliminary report. J. Am. Med. Assoc. 143 4 (1950) 336-338
24. Lonardo F., et al. Evidence for the epidermal growth factor receptor as a target for lung cancer prevention. Clin. Cancer Res. 8 1 (2002) 54-60
25. Mackay J., et al. The Cancer Atlas (2006), American Cancer Society, Atlanta
26. Meckley D., et al. A responsive, sensitive, and reproducible dermal tumor promotion assay for the comparative evaluation of cigarette smoke condensates. Regul. Toxicol. Pharmacol. 39 2 (2004) 135-149
27. Miura K., et al. Laser capture microdissection and microarray expression analysis of lung adenocarcinoma reveals tobacco smoking- and prognosis-related molecular profiles. Cancer Res. 62 11 (2002) 3244-3250
28. Miyazu Y.M., et al. Telomerase expression in noncancerous bronchial epithelia is a possible marker of early development of lung cancer. Cancer Res. 65 21 (2005) 9623-9627
29. Nguyen C.T., et al. Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2′-deoxycytidine. Cancer Res. 62 22 (2002) 6456-6461
30. Niklinski J., et al. Prognostic molecular markers in non-small cell lung cancer. Lung Cancer 34 Suppl. 2 (2001) S53-S58
31. Powell C.A., et al. Loss of heterozygosity in epithelial cells obtained by bronchial brushing: clinical utility in lung cancer. Clin. Cancer Res. 5 8 (1999) 2025-2034
32. Santiago L.N., et al. The effect of different doses of cigarette smoke in a mouse lung tumor model. Int. J. Clin. Exp. Pathol. 2 2 (2009) 176-181
33. Siddiq F., et al. Increased osteonectin expression is associated with malignant transformation and tumor associated fibrosis in the lung. Lung Cancer 45 2 (2004) 197-205
34. Spira A., et al. Effects of cigarette smoke on the human airway epithelial cell transcriptome. Proc. Natl. Acad. Sci. U.S.A. 101 27 (2004) 10143-10148
35. Spira A., et al. Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat. Med. 13 3 (2007) 361-366
36. Willey J.C., et al. Immortalization of normal human bronchial epithelial cells by human papillomaviruses 16 or 18. Cancer Res. 51 19 (1991) 5370-5377
37. Wistuba I.I., et al. Molecular damage in the bronchial epithelium of current and former smokers. J. Natl. Cancer Inst. 89 18 (1997) 1366-1373
38. Wistuba I.I., Mao L., and Gazdar A.F. Smoking molecular damage in bronchial epithelium. Oncogene 21 48 (2002) 7298-7306
39. Yao R., et al. Budesonide exerts its chemopreventive efficacy during mouse lung tumorigenesis by modulating gene expressions. Oncogene 23 46 (2004) 7746-7752
40. Yashima K., et al. Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas. Cancer Res. 57 12 (1997) 2373-2377
41. Yoshimizu T., et al. The H19 locus acts in vivo as a tumor suppressor. Proc. Natl. Acad. Sci. U.S.A. 105 34 (2008) 12417-12422
42. Zhou H., Calaf G.M., and Hei T.K. Malignant transformation of human bronchial epithelial cells with the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Int. J. Cancer 106 6 (2003) 821-826