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Volumn 63, Issue 2, 2009, Pages 103-112

Formulation optimization of serratiopeptidase-loaded PLGA microspheres using selected variables

Author keywords

Biodegradable; Factorial design; Microspheres; Proteolytic activity; Serratiopeptidase; Wound healing

Indexed keywords

MICROSPHERE; POLYGLACTIN; SERRATIOPEPTIDASE; LACTIC ACID; PEPTIDE HYDROLASE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

EID: 68349106904     PISSN: 10797440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (5)

References (34)
  • 1
  • 2
    • 0006499108 scopus 로고
    • The effective period of preventive antibiotic action in experimental incisions and dermal lesions
    • Burke, J. F. The effective period of preventive antibiotic action in experimental incisions and dermal lesions. Surgery 1961, 50 (July), 161-168.
    • (1961) Surgery , vol.50 , Issue.JULY , pp. 161-168
    • Burke, J.F.1
  • 3
    • 3142511048 scopus 로고    scopus 로고
    • Streaming of proteolytic enzyme solutions for wound debridement: A feasibility study
    • Yaakobi, T.; Roth, D.; Chen, Y.; Freeman, A. Streaming of proteolytic enzyme solutions for wound debridement: a feasibility study. Wounds 2004, 16 (6), 201-205. (Pubitemid 38901160)
    • (2004) Wounds , vol.16 , Issue.6 , pp. 201-205
    • Yaakobi, T.1    Roth, D.2    Chen, Y.3    Freeman, A.4
  • 4
    • 17344391922 scopus 로고    scopus 로고
    • Vitamin A-loaded solid lipid nanoparticles for topical use: Drug release properties
    • Jenning, V.; Schafer-Korting, M.; Gohla, S. Vitamin A-loaded solid lipid nanoparticles for topical use: drug release properties. J. Controlled Release 2000, 66 (2-3), 115-126.
    • (2000) J. Controlled Release , vol.66 , Issue.2-3 , pp. 115-126
    • Jenning, V.1    Schafer-Korting, M.2    Gohla, S.3
  • 5
    • 0024511417 scopus 로고
    • The treatment of breast engorgement with Serrapeptase (Danzen): A randomized double-blind controlled trial
    • Kee, W. H.; Tan, S. L.; Lee, V.; Salmon, Y. M. The treatment of breast engorgement with Serrapeptase (Danzen): a randomized double-blind controlled trial. Singapore Med. J. 1989, 30 (1), 48-54.
    • (1989) Singapore Med. J. , vol.30 , Issue.1 , pp. 48-54
    • Kee, W.H.1    Tan, S.L.2    Lee, V.3    Salmon, Y.M.4
  • 6
    • 0025073292 scopus 로고
    • Effects of orally administered drugs on dynamic viscoelasticity of human nasal mucus
    • Majima, Y.; Hirata, K.; Takeuchi, K.; Hattori, M.; Sakakura, Y. Effects of orally administered drugs on dynamic viscoelasticity of human nasal mucus. Am. Rev. Respir. Dis. 1990, 141 (1), 79-83.
    • (1990) Am. Rev. Respir. Dis. , vol.141 , Issue.1 , pp. 79-83
    • Majima, Y.1    Hirata, K.2    Takeuchi, K.3    Hattori, M.4    Sakakura, Y.5
  • 7
    • 33748353240 scopus 로고    scopus 로고
    • Nanocarriers: Promising vehicle for bioactive drugs
    • Rawat, M.; Singh, D.; Saraf, S.; Saraf, S. Nanocarriers: promising vehicle for bioactive drugs. Biol. Pharm. Bull. 2006, 29 (9), 1790-1798.
    • (2006) Biol. Pharm. Bull. , vol.29 , Issue.9 , pp. 1790-1798
    • Rawat, M.1    Singh, D.2    Saraf, S.3    Saraf, S.4
  • 8
    • 0029335538 scopus 로고
    • Biodegradable polymers for protein and peptide drug delivery
    • Gombotz, W. R.; Pettit, D. K. Biodegradable polymers for protein and peptide drug delivery. Bioconjug. Chem. 1995, 6 (4), 332-351.
    • (1995) Bioconjug. Chem. , vol.6 , Issue.4 , pp. 332-351
    • Gombotz, W.R.1    Pettit, D.K.2
  • 10
    • 0028323503 scopus 로고
    • Effect of collagen microparticles on the stability of retinol and its absorption into hairless mouse skin in vitro
    • Rössler, B.; Kreuter, J.; Ross, G. Effect of collagen microparticles on the stability of retinol and its adsorption into hairless mouse skin in vitro. Pharmazie 1994, 49 (2-3), 175-179. (Pubitemid 24093107)
    • (1994) Pharmazie , vol.49 , Issue.2-3 , pp. 175-179
    • Rossler, B.1    Kreuter, J.2    Ross, G.3
  • 11
    • 0033958303 scopus 로고    scopus 로고
    • Preparation of microcapsules for skin allergy testing by solvent evaporation process
    • Brosse, C.; Soutif, J. C.; Bross, J. C. Preparation of microcapsules for skin allergy testing by solvent evaporation process. J. Microencapsul. 2000, 17 (1), 111-116.
    • (2000) J. Microencapsul. , vol.17 , Issue.1 , pp. 111-116
    • Brosse, C.1    Soutif, J.C.2    Bross, J.C.3
  • 12
    • 0023901210 scopus 로고
    • A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid
    • Ogawa, Y.; Yamamoto, M.; Okada, H.; Yashiki, T.; Shimamoto, T. A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid. Chem Pharm Bull. (Tokyo) 1988, 36 (3), 1095-1103.
    • (1988) Chem Pharm Bull. (Tokyo) , vol.36 , Issue.3 , pp. 1095-1103
    • Ogawa, Y.1    Yamamoto, M.2    Okada, H.3    Yashiki, T.4    Shimamoto, T.5
  • 13
    • 0002914655 scopus 로고    scopus 로고
    • Polylactic and Polyglycolic Acid Acids as Drug Carriers
    • Wise, D. L., Ed.; Marcel Dekker: New York
    • Brannon-Peppas, L.; Vert, M. Polylactic and Polyglycolic Acid Acids as Drug Carriers. In Handbook of Pharmaceutical Controlled Release Technology; Wise, D. L., Ed.; Marcel Dekker: New York, 2000; pp 99-130.
    • (2000) Handbook of Pharmaceutical Controlled Release Technology , pp. 99-130
    • Brannon-Peppas, L.1    Vert, M.2
  • 14
    • 39849104152 scopus 로고    scopus 로고
    • Development and in vitro evaluation of alginate gel-encapsulated, chitosan-coated ceramic nanocores for oral delivery of enzyme
    • Rawat, M.; Singh, D.; Saraf, S.; Saraf, S. Development and in vitro evaluation of alginate gel-encapsulated, chitosan-coated ceramic nanocores for oral delivery of enzyme. Drug Dev. Ind. Pharm. 2008, 34 (2), 181-188.
    • (2008) Drug Dev. Ind. Pharm. , vol.34 , Issue.2 , pp. 181-188
    • Rawat, M.1    Singh, D.2    Saraf, S.3    Saraf, S.4
  • 15
    • 38549085762 scopus 로고    scopus 로고
    • Influence of selected formulation variables on the preparation of enzyme entrapped Eudragit S100 microspheres
    • Rawat, M.; Saraf, S.; Saraf, S. Influence of selected formulation variables on the preparation of enzyme entrapped Eudragit S100 microspheres. AAPS PharmSciTech 2007, 8 (4), E116.
    • (2007) AAPS PharmSciTech , vol.8 , Issue.4
    • Rawat, M.1    Saraf, S.2    Saraf, S.3
  • 17
    • 0034714882 scopus 로고    scopus 로고
    • Robustness testing, using experimental design, of a flow-through dissolution method for a product where actives have markedly differing solubility properties
    • Bloomfield, M. S.; Butler, W. C. Robustness testing, using experimental design, of a flow-through dissolution method for a product where actives have markedly differing solubility properties. Int. J. Pharm. 2000, 206 (1-2), 55-61.
    • (2000) Int. J. Pharm. , vol.206 , Issue.1-2 , pp. 55-61
    • Bloomfield, M.S.1    Butler, W.C.2
  • 18
    • 0025731293 scopus 로고
    • Controlled delivery system for proteins based on poly(lactic/glycolic acid) microspheres
    • Cohen, S.; Yoshiaka, T.; Lucarelli, M.; Hwang, L. H.; Langer, R. Controlled delivery system for proteins based on poly(lactic/glycolic acid) microspheres. Pharm. Res. 1991, 8 (6), 713-720.
    • (1991) Pharm. Res. , vol.8 , Issue.6 , pp. 713-720
    • Cohen, S.1    Yoshiaka, T.2    Lucarelli, M.3    Hwang, L.H.4    Langer, R.5
  • 19
    • 27844603314 scopus 로고    scopus 로고
    • Eudragit S100 entrapped insulin microspheres for oral delivery
    • Jain, D.; Panda, A. K.; Majumdar, D. K. Eudragit S100 entrapped insulin microspheres for oral delivery. AAPS PharmSciTech 2005, 6 (1), E100-E107.
    • (2005) AAPS PharmSciTech , vol.6 , Issue.1
    • Jain, D.1    Panda, A.K.2    Majumdar, D.K.3
  • 20
    • 0034602127 scopus 로고    scopus 로고
    • Influence of different nonionic surfactants on the properties of PLGA insulin-loaded microspheres
    • Rosa, G. D.; Iommelli, R.; La Rotonda, M. I.; Miro, A.; Quaglia, F. Influence of different nonionic surfactants on the properties of PLGA insulin-loaded microspheres. J. Controlled Release 2000, 69, 283-295.
    • (2000) J. Controlled Release , vol.69 , pp. 283-295
    • Rosa, G.D.1    Iommelli, R.2    La Rotonda, M.I.3    Miro, A.4    Quaglia, F.5
  • 21
    • 0035176137 scopus 로고    scopus 로고
    • Effect of adding non-volatile oil as a core material for the floating microspheres prepared by emulsion solvent diffusion method
    • Lee, J. H.; Park, T. G.; Lee, Y. B.; Shin, S. C.; Choi, H. K. Effect of adding non-volatile oil as a core material for the floating microspheres prepared by emulsion solvent diffusion method. J. Microencapsul. 2001, 18 (1), 65-75.
    • (2001) J. Microencapsul. , vol.18 , Issue.1 , pp. 65-75
    • Lee, J.H.1    Park, T.G.2    Lee, Y.B.3    Shin, S.C.4    Choi, H.K.5
  • 22
    • 33745568664 scopus 로고    scopus 로고
    • Effect of processing variables on micro particulate system of aceclofenac
    • Dashora, K.; Saraf, S.; Saraf, S. Effect of processing variables on micro particulate system of aceclofenac. Pak. J. Pharm. Sci. 2006, 19 (1), 6-10.
    • (2006) Pak. J. Pharm. Sci. , vol.19 , Issue.1 , pp. 6-10
    • Dashora, K.1    Saraf, S.2    Saraf, S.3
  • 23
    • 70849128673 scopus 로고    scopus 로고
    • Development and validation of derivative spectrophotometric method for determination of serratiopeptidase in pharmaceutical formulation
    • Saudagar, R. B.; Rawat, M.; Singh, D.; Saraf, S.; Saraf, S. Development and validation of derivative spectrophotometric method for determination of serratiopeptidase in pharmaceutical formulation. Oriental J. Chem. 2008, 23, 113-114.
    • (2008) Oriental J. Chem. , vol.23 , pp. 113-114
    • Saudagar, R.B.1    Rawat, M.2    Singh, D.3    Saraf, S.4    Saraf, S.5
  • 24
    • 38549145299 scopus 로고    scopus 로고
    • Committee on Institute of Medicine 4th ed. Washington, DC; National Academic Press
    • Committee on Institute of Medicine. Food and Chemical Codex, 4th ed. Washington, DC; National Academic Press, 2003.
    • (2003) Food and Chemical Codex
  • 25
    • 0028815624 scopus 로고
    • Optimization of preparative conditions for polylactide (PLA) microspheres containing ovalbumin
    • Uchida, T.; Yoshida, K.; Ninomiya, A.; Goto, S. Optimization of preparative conditions for polylactide (PLA) microspheres containing ovalbumin. Chem. Pharm. Bull. (Tokyo) 1995, 43 (9), 1569-1573.
    • (1995) Chem. Pharm. Bull. (Tokyo) , vol.43 , Issue.9 , pp. 1569-1573
    • Uchida, T.1    Yoshida, K.2    Ninomiya, A.3    Goto, S.4
  • 26
    • 0025053154 scopus 로고
    • Biodegradable poly(lactic acid) and poly(lactide-co-glycolide) microcapsules: Problems associated with preparative techniques and release properties
    • Jalil, R.; Nixon, J. R. Biodegradable poly(lactic acid) and poly(lactide-co-glycolide) microcapsules: problems associated with preparative techniques and release properties. J. Microencapsul. 1990, 7 (3), 297-325.
    • (1990) J. Microencapsul. , vol.7 , Issue.3 , pp. 297-325
    • Jalil, R.1    Nixon, J.R.2
  • 27
    • 0030885049 scopus 로고    scopus 로고
    • Production, purification and characterization of a 50-kDa extracellular metalloprotease from Serratia marcescens
    • Salamone, P. R.; Wodzinski, R. J. Production, purification and characterization of a 50-kDa extracellular metalloprotease from Serratia marcescens. Appl. Microbiol. Biotechnol. 1997, 48 (3), 317-324.
    • (1997) Appl. Microbiol. Biotechnol. , vol.48 , Issue.3 , pp. 317-324
    • Salamone, P.R.1    Wodzinski, R.J.2
  • 29
    • 1542328830 scopus 로고    scopus 로고
    • Optimisation of aciclovir poly(D,L-lactide-coglycolide) microspheres for intravitreal administration using a factorial design study
    • Martinez-Sancho, C.; Herrero-Vanrell, R.; Negro, S. Optimisation of aciclovir poly(D,L-lactide-coglycolide) microspheres for intravitreal administration using a factorial design study. Int. J. Pharm. 2004, 273 (1-2), 45-56.
    • (2004) Int. J. Pharm. , vol.273 , Issue.1-2 , pp. 45-56
    • Martinez-Sancho, C.1    Herrero-Vanrell, R.2    Negro, S.3
  • 30
    • 0035218327 scopus 로고    scopus 로고
    • In vitro modified release of acyclovir from ethyl cellulose microspheres
    • 2001
    • Cheu, S. J.; Chen, R. R.; Chen, P. F.; Lin, W. J. In vitro modified release of acyclovir from ethyl cellulose microspheres. J. Microencapsul. 2001, 18 (5), 559-(2001).
    • (2001) J. Microencapsul. , vol.18 , Issue.5 , pp. 559
    • Cheu, S.J.1    Chen, R.R.2    Chen, P.F.3    Lin, W.J.4
  • 31
    • 0033981065 scopus 로고    scopus 로고
    • Studies on microencapsulation of 5-fluorouracil with poly(ortho ester) polymers
    • Lin, Y. H.; Vasavada, R. C. Studies on microencapsulation of 5-fluorouracil with poly(ortho ester) polymers. J. Microencapsul. 2000, 17 (1), 1-11.
    • (2000) J. Microencapsul. , vol.17 , Issue.1 , pp. 1-11
    • Lin, Y.H.1    Vasavada, R.C.2
  • 32
    • 2442421920 scopus 로고    scopus 로고
    • Formulation optimization of water-in-oil-water multiple emulsion for intestinal insulin delivery
    • Onuki, Y.; Morishita, M.; Takayama, K. Formulation optimization of water-in-oil-water multiple emulsion for intestinal insulin delivery. J. Controlled Release 2004, 97 (1), 91-99.
    • (2004) J. Controlled Release , vol.97 , Issue.1 , pp. 91-99
    • Onuki, Y.1    Morishita, M.2    Takayama, K.3
  • 33
    • 33746810003 scopus 로고    scopus 로고
    • Pegylated protein encapsulated multivesicular liposomes: A novel approach for sustained release of Interferon-α
    • Vyas, S. P.; Rawat, M.; Rawat, A.; Mahor, S.; Gupta, P. N. Pegylated protein encapsulated multivesicular liposomes: a novel approach for sustained release of Interferon-α. Drug Dev. Ind. Pharm. 2006, 32 (6), 699-707.
    • (2006) Drug Dev. Ind. Pharm. , vol.32 , Issue.6 , pp. 699-707
    • Vyas, S.P.1    Rawat, M.2    Rawat, A.3    Mahor, S.4    Gupta, P.N.5
  • 34
    • 0033959003 scopus 로고    scopus 로고
    • Mathematical modeling of diffusion-mediated release from bulk degrading matrices
    • Tzafiriri, A. R. Mathematical modeling of diffusion-mediated release from bulk degrading matrices. J. Controlled Release 2000, 63 (1-2), 69-79.
    • (2000) J. Controlled Release , vol.63 , Issue.1-2 , pp. 69-79
    • Tzafiriri, A.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.