메뉴 건너뛰기




Volumn 20, Issue 5, 2009, Pages 477-485

Effect of dexamethasone on respiratory syncytial virus-induced lung inflammation in children: Results of a randomized, placebo controlled clinical trial

Author keywords

Bronchiolitis; Children; Corticosteroids; Cytokines; Respiratory syncytial virus

Indexed keywords

ALPHA INTERFERON; DEXAMETHASONE; EOTAXIN; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PLACEBO; RANTES; TUMOR NECROSIS FACTOR ALPHA;

EID: 68349100223     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2009.00852.x     Document Type: Article
Times cited : (42)

References (27)
  • 1
    • 0036020209 scopus 로고    scopus 로고
    • Respiratory syncytial virus-coded pediatric hospitalizations, 1997 to 1999
    • Leader S, Kohlhase K. Respiratory syncytial virus-coded pediatric hospitalizations, 1997 to 1999. Pediatr Infect Dis J. 2002 : 21 : 629 32.
    • (2002) Pediatr Infect Dis J. , vol.21 , pp. 629-32
    • Leader, S.1    Kohlhase, K.2
  • 2
    • 0842327826 scopus 로고    scopus 로고
    • National disease burden of respiratory viruses detected in children by polymerase chain reaction
    • Henrickson KJ, Hoover S, Kehl KS, Hua W. National disease burden of respiratory viruses detected in children by polymerase chain reaction. Pediatr Infect Dis J. 2004 : 23 : S11 8.
    • (2004) Pediatr Infect Dis J. , vol.23 , pp. 11-8
    • Henrickson, K.J.1    Hoover, S.2    Kehl, K.S.3    Hua, W.4
  • 4
    • 0029045869 scopus 로고
    • The clinical efficacy of nebulized racemic epinephrine and albuterol in acute bronchiolitis
    • Reijonen T, Korppi M, Pitkakangas S, Tenhola S, Remes K. The clinical efficacy of nebulized racemic epinephrine and albuterol in acute bronchiolitis. Arch Pediatr Adolesc Med. 1995 : 149 : 686 92.
    • (1995) Arch Pediatr Adolesc Med. , vol.149 , pp. 686-92
    • Reijonen, T.1    Korppi, M.2    Pitkakangas, S.3    Tenhola, S.4    Remes, K.5
  • 5
    • 68349098687 scopus 로고    scopus 로고
    • Respiratory syncytial virus
    • American Academy of Pediatrics. In. Pickering, L.K. Baker, C.J. Long, S.S. McMillan, J.A. eds. 27th ed. Elk Grove Village, IL. American Academy of Pediatrics
    • American Academy of Pediatrics. Respiratory syncytial virus. In : Pickering LK, Baker CJ, Long SS, McMillan JA, eds. Red book: 2006 report of the Committee on Infectious Diseases. 27th ed. Elk Grove Village, IL : American Academy of Pediatrics, 2006 : 27.
    • (2006) Red Book: 2006 Report of the Committee on Infectious Diseases. , pp. 27
  • 6
    • 16644377134 scopus 로고    scopus 로고
    • Efficacy of interventions for bronchiolitis in critically ill infants: A systematic review and meta-analysis
    • Davison C, Ventre KM, Luchetti M, Randolph AG. Efficacy of interventions for bronchiolitis in critically ill infants: a systematic review and meta-analysis. Pediatr Crit Care Med. 2004 : 5 : 482 9.
    • (2004) Pediatr Crit Care Med. , vol.5 , pp. 482-9
    • Davison, C.1    Ventre, K.M.2    Luchetti, M.3    Randolph, A.G.4
  • 7
    • 0038353702 scopus 로고    scopus 로고
    • Randomized controlled trial of nebulized adrenaline in acute bronchiolitis
    • Hariprakash S, Alexander J, Carroll W, et al. Randomized controlled trial of nebulized adrenaline in acute bronchiolitis. Pediatr Allergy Immunol. 2003 : 14 : 134 9.
    • (2003) Pediatr Allergy Immunol. , vol.14 , pp. 134-9
    • Hariprakash, S.1    Alexander, J.2    Carroll, W.3
  • 8
    • 0027280484 scopus 로고
    • A comparison between nebulized terbutaline, nebulized corticosteroid and systemic corticosteroid for acute wheezing in children up to 18 months of age
    • Daugbjerg P, Brenoe E, Forchhammer H, et al. A comparison between nebulized terbutaline, nebulized corticosteroid and systemic corticosteroid for acute wheezing in children up to 18 months of age. Acta Paediatr. 1993 : 82 : 547 51.
    • (1993) Acta Paediatr. , vol.82 , pp. 547-51
    • Daugbjerg, P.1    Brenoe, E.2    Forchhammer, H.3
  • 10
    • 0036569233 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of dexamethasone in severe respiratory syncytial virus (RSV) infection: Effects on RSV quantity and clinical outcome
    • Buckingham SC, Jafri HS, Bush AJ, et al. A randomized, double-blind, placebo-controlled trial of dexamethasone in severe respiratory syncytial virus (RSV) infection: effects on RSV quantity and clinical outcome. J Infect Dis. 2002 : 185 : 1222 8.
    • (2002) J Infect Dis. , vol.185 , pp. 1222-8
    • Buckingham, S.C.1    Jafri, H.S.2    Bush, A.J.3
  • 12
    • 0037650224 scopus 로고    scopus 로고
    • Dexamethasone for treatment of patients mechanically ventilated for lower respiratory tract infection caused by respiratory syncytial virus
    • van Woensel JB, van Aalderen WM, de Weerd W, et al. Dexamethasone for treatment of patients mechanically ventilated for lower respiratory tract infection caused by respiratory syncytial virus. Thorax. 2003 : 58 : 383 7.
    • (2003) Thorax. , vol.58 , pp. 383-7
    • Van Jb, W.1    Van Wm, A.2    De, W.W.3
  • 13
    • 22944484101 scopus 로고    scopus 로고
    • Dexamethasone inhalations in RSV bronchiolitis: A double-blind, placebo-controlled study
    • Bentur L, Shoseyov D, Feigenbaum D, Gorichovsky Y, Bibi H. Dexamethasone inhalations in RSV bronchiolitis: a double-blind, placebo-controlled study. Acta Paediatr. 2005 : 94 : 866 71.
    • (2005) Acta Paediatr. , vol.94 , pp. 866-71
    • Bentur, L.1    Shoseyov, D.2    Feigenbaum, D.3    Gorichovsky, Y.4    Bibi, H.5
  • 14
    • 34547230736 scopus 로고    scopus 로고
    • A multicenter, randomized, controlled trial of dexamethasone for bronchiolitis
    • Corneli HM, Zorc JJ, Mahajan P, et al. A multicenter, randomized, controlled trial of dexamethasone for bronchiolitis. N Engl J Med. 2007 : 357 : 331 9.
    • (2007) N Engl J Med. , vol.357 , pp. 331-9
    • Corneli, H.M.1    Zorc, J.J.2    Mahajan, P.3
  • 15
    • 0034938404 scopus 로고    scopus 로고
    • Nebulized budesonide after hospitalization for recurrent bronchial obstruction in children younger than 18 months
    • Lodrup Carlsen KC, Carlsen KH, Nikander K, et al. Nebulized budesonide after hospitalization for recurrent bronchial obstruction in children younger than 18 months. Pediatr Allergy Immunol. 2001 : 12 : 159 65.
    • (2001) Pediatr Allergy Immunol. , vol.12 , pp. 159-65
    • Kc, L.C.1    Carlsen, K.H.2    Nikander, K.3
  • 16
    • 0033065482 scopus 로고    scopus 로고
    • Elevated cytokine concentrations in the nasopharyngeal and tracheal secretions of children with respiratory syncytial virus disease
    • Sheeran P, Jafri H, Carubelli C, et al. Elevated cytokine concentrations in the nasopharyngeal and tracheal secretions of children with respiratory syncytial virus disease. Pediatr Infect Dis J. 1999 : 18 : 115 22.
    • (1999) Pediatr Infect Dis J. , vol.18 , pp. 115-22
    • Sheeran, P.1    Jafri, H.2    Carubelli, C.3
  • 17
    • 2942748333 scopus 로고    scopus 로고
    • Circulating cytokines in primary Sjogren's syndrome determined by a multiplex cytokine array system
    • Szodoray P, Alex P, Brun JG, Centola M, Jonsson R. Circulating cytokines in primary Sjogren's syndrome determined by a multiplex cytokine array system. Scand J Immunol. 2004 : 59 : 592 9.
    • (2004) Scand J Immunol. , vol.59 , pp. 592-9
    • Szodoray, P.1    Alex, P.2    Brun, J.G.3    Centola, M.4    Jonsson, R.5
  • 18
    • 10044230781 scopus 로고    scopus 로고
    • Human metapneumovirus persists in BALB/c mice despite the presence of neutralizing antibodies
    • Alvarez R, Harrod KS, Shieh WJ, Zaki S, Tripp RA. Human metapneumovirus persists in BALB/c mice despite the presence of neutralizing antibodies. J Virol. 2004 : 78 : 14003 11.
    • (2004) J Virol. , vol.78 , pp. 14003-11
    • Alvarez, R.1    Harrod, K.S.2    Shieh, W.J.3    Zaki, S.4    Tripp, R.A.5
  • 19
    • 17044371439 scopus 로고    scopus 로고
    • Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis
    • McNamara PS, Flanagan BF, Hart CA, Smyth RL. Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis. J Infect Dis. 2005 : 191 : 1225 32.
    • (2005) J Infect Dis. , vol.191 , pp. 1225-32
    • McNamara, P.S.1    Flanagan, B.F.2    Hart, C.A.3    Smyth, R.L.4
  • 20
    • 0035999362 scopus 로고    scopus 로고
    • Beta-chemokines, but neither T helper type 1 nor T helper type 2 cytokines, correlate with severity of illness during respiratory syncytial virus infection
    • Welliver RC, Garofalo RP, Ogra PL. Beta-chemokines, but neither T helper type 1 nor T helper type 2 cytokines, correlate with severity of illness during respiratory syncytial virus infection. Pediatr Infect Dis J. 2002 : 21 : 457 61.
    • (2002) Pediatr Infect Dis J. , vol.21 , pp. 457-61
    • Welliver, R.C.1    Garofalo, R.P.2    Ogra, P.L.3
  • 21
    • 0034110831 scopus 로고    scopus 로고
    • Monocyte IL-10 production during respiratory syncytial virus bronchiolitis is associated with recurrent wheezing in a one-year follow-up study
    • Bont L, Heijnen CJ, Kavelaars A, et al. Monocyte IL-10 production during respiratory syncytial virus bronchiolitis is associated with recurrent wheezing in a one-year follow-up study. Am J Respir Crit Care Med. 2000 : 161 : 1518 23.
    • (2000) Am J Respir Crit Care Med. , vol.161 , pp. 1518-23
    • Bont, L.1    Heijnen, C.J.2    Kavelaars, A.3
  • 22
    • 0035425846 scopus 로고    scopus 로고
    • Local interferon-gamma levels during respiratory syncytial virus lower respiratory tract infection are associated with disease severity
    • Bont L, Heijnen CJ, Kavelaars A, et al. Local interferon-gamma levels during respiratory syncytial virus lower respiratory tract infection are associated with disease severity. J Infect Dis. 2001 : 184 : 355 8.
    • (2001) J Infect Dis. , vol.184 , pp. 355-8
    • Bont, L.1    Heijnen, C.J.2    Kavelaars, A.3
  • 23
    • 0032981366 scopus 로고    scopus 로고
    • Macrophage inflammatory protein-1alpha and RANTES are present in nasal secretions during ongoing upper respiratory tract infection
    • Bonville CA, Rosenberg HF, Domachowske JB. Macrophage inflammatory protein-1alpha and RANTES are present in nasal secretions during ongoing upper respiratory tract infection. Pediatr Allergy Immunol. 1999 : 10 : 39 44.
    • (1999) Pediatr Allergy Immunol. , vol.10 , pp. 39-44
    • Bonville, C.A.1    Rosenberg, H.F.2    Domachowske, J.B.3
  • 24
    • 34248157702 scopus 로고    scopus 로고
    • Immunopathogenesis of respiratory syncytial virus bronchiolitis
    • Bennett BL, Garofalo RP, Cron SG, et al. Immunopathogenesis of respiratory syncytial virus bronchiolitis. J Infect Dis. 2007 : 195 : 1532 40.
    • (2007) J Infect Dis. , vol.195 , pp. 1532-40
    • Bennett, B.L.1    Garofalo, R.P.2    Cron, S.G.3
  • 25
    • 34047205270 scopus 로고    scopus 로고
    • Severe human lower respiratory tract illness caused by respiratory syncytial virus and influenza virus is characterized by the absence of pulmonary cytotoxic lymphocyte responses
    • Welliver TP, Garofalo RP, Hosakote Y, et al. Severe human lower respiratory tract illness caused by respiratory syncytial virus and influenza virus is characterized by the absence of pulmonary cytotoxic lymphocyte responses. J Infect Dis. 2007 : 195 : 1126 36.
    • (2007) J Infect Dis. , vol.195 , pp. 1126-36
    • Welliver, T.P.1    Garofalo, R.P.2    Hosakote, Y.3
  • 26
    • 0033426899 scopus 로고    scopus 로고
    • Prednisolone treatment of respiratory syncytial virus infection: A randomized controlled trial of 147 infants
    • Bulow SM, Nir M, Levin E, et al. Prednisolone treatment of respiratory syncytial virus infection: a randomized controlled trial of 147 infants. Pediatrics. 1999 : 104 : e77.
    • (1999) Pediatrics. , vol.104 , pp. 77
    • Bulow, S.M.1    Nir, M.2    Levin, E.3
  • 27
    • 68349121319 scopus 로고    scopus 로고
    • Impact of Dexamethasone Therapy on TNF-α, IL-8, and RANTES Concentrations in the Lower Respiratory Tract Secretions of Children Intubated for Respiratory Syncytial Virus (RSV) Disease. Abstract 1564
    • Boston, MA
    • Jafri HS, Carubelli CM, Buckingham SC, et al. Impact of Dexamethasone Therapy on TNF-α, IL-8, and RANTES Concentrations in the Lower Respiratory Tract Secretions of Children Intubated for Respiratory Syncytial Virus (RSV) Disease. Abstract 1564. 2000 Pediatric Academic Societies meeting. Boston, MA, 2000.
    • (2000) 2000 Pediatric Academic Societies Meeting.
    • Jafri, H.S.1    Carubelli, C.M.2    Buckingham, S.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.