Antitumor effect of retinoic acid receptor-β2 associated with suppression of cyclooxygenase-2

Cancer Prevention Research

Volumn 2, Issue 3, 2009, Pages 274-280

  Song, Shumei ^a   Guan, Baoxiang ^a   Men, Taoyan ^a   Hoque, Ashraful ^a   Lotan, Reuben ^a   Xu, Xiao Chun ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYCLOOXYGENASE 2; ISOTRETINOIN; MESSENGER RNA; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR BETA 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; ESOPHAGUS CANCER; EXPRESSION VECTOR; GENE EXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKOPLAKIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; STABLE TRANSFECTION; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS; CELL SURVIVAL; CYCLOOXYGENASE 2 INHIBITORS; DNA, COMPLEMENTARY; ESOPHAGEAL NEOPLASMS; GENETIC VECTORS; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; RECEPTORS, RETINOIC ACID; TRANSFECTION;

EID: 68349093855     PISSN: 19406207     EISSN: None     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-08-0180     Document Type: Article

References (38)

1. Soprano DR, Qin P, Soprano KJ. Retinoic acid receptors and cancers. Annu Rev Nutr 2004;24:201-221
2. Xu X-C. Tumor-suppressive activity of retinoic acid receptor-β in cancer. Cancer Lett 2007;253:14-24. (Pubitemid 46874724)
3. Cheung B, Hocker JE, Smith SA, Norris MD, Haber M, Marshall GM. Favorable prognostic significance of high-level retinoic acid receptor β expression in neuroblastoma mediated by effects on cell cycle regulation. Oncogene 1998;17:751-759 (Pubitemid 28412496)
4. Wang XD, Liu C, Branson RT, Smith DE, Krinsky NI, Russell M. Retinoid signaling and activator protein-1 expression in ferrets given β-carotene supplements and exposed to tobacco smoke. J Natl Cancer Inst 1999;91:60-66 (Pubitemid 29042444)
5. Vuillemenot BR, Pulling LC, Palmisano WA, Hutt JA, Belinsky SA. Carcinogen exposure differentially modulates RAR-β promoter hypermethylation, an early and frequent event in mouse lung carcinogenesis. Carcinogenesis 2004;25:623-629
6. Song S, Xu XC. Effect of benzo[a]pyrene diol epoxide on expression of retinoic acid receptor-β in immortalized esophageal epithelial cells and esophageal cancer cells. Biochem Biophys Res Commun 2001;281:872-877 (Pubitemid 32917811)
7. 2 expression. Oncogene 2005;24:8268-8276 (Pubitemid 43250919)
8. McGregor F, Wagner E, Felix D, Soutar D, Parkinson K, Harrison PR. Inappropriate retinoic acid receptor-β expression in oral dysplasias: correlation with acquisition of the immortal phenotype. Cancer Res 1997;57:3886-3889 (Pubitemid 27427669)
9. Muntoni A, Fleming J, Gordon KE, et al. Senescing oral dysplasias are not immortalized by ectopic expression of hTERT alone without other molecular changes, such as loss of INK4A and/or retinoic acid receptor-β: but p53 mutations are not necessarily required. Oncogene 2003;22:7804-7808 (Pubitemid 37485539)
10. Fang MZ, Wang Y, Ai N, et al. Tea polyphenol (-)-epigallocatechin-3- gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res 2003;63:7563-7570 (Pubitemid 37466673)
11. Li M, Song S, Lippman SM, et al. Induction of retinoic acid receptor-β suppresses cyclooxygenase-2 expression in esophageal cancer cells. Oncogene 2002;21:411-418 (Pubitemid 34123803)
12. 2 on tumor cell growth and gene expression through binding to and inhibiting RhoA. Cancer Res 2006;66:7111-7118
13. Lotan R, Xu XC, Lippman SM, et al. Suppression of retinoic acid receptor-β in premalignant oral lesions and its up-regulation by isotretinoin. N Engl J Med 1995;332:1405-1410
14. Xu XC, Liu X, Tahara E, Lippman SM, Lotan R. Expression and up-regulation of retinoic acid receptor-β is associated with retinoid sensitivity and colony formation in esophageal cancer cell lines. Cancer Res 1999;59:2477-2483 (Pubitemid 29242300)
15. Khuri FR, Wu H, Lee JJ, et al. Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin Cancer Res 2001;7:861-867 (Pubitemid 32708722)
16. Xu X-C, Lee JJ, Wu TT, Hoque A, Ajani JA, Lippman SM. Increased retinoic acid receptor-B4 correlates in vivo with reduced retinoic acid receptor-β2 in esophageal squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 2005;14:826-829
17. Houle B, Rochette-Egly C, Bradley WE. Tumor-suppressive effect of the retinoic acid receptor β in human epidermoid lung cancer cells. Proc Natl Acad Sci U S A 1993;90:985-989 (Pubitemid 23053935)
18. Sun SY, Schroeder CP, Yue P, Lotan D, Hong WK, Lotan R. Enhanced growth inhibition and apoptosis induction in NSCLC cell lines by combination of celecoxib and 4HPR at clinically relevant concentrations. Cancer Biol Ther 2005;4:407-413 (Pubitemid 41351257)
19. Liu Y, Lee MO, Wang HG, et al. Retinoic acid receptor β mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells. Mol Cell Biol 1996;16:1138-1149 (Pubitemid 26061685)
20. Seewaldt VL, Johnson BS, Parker MB, Collins SJ, Swisshelm K. Expression of retinoic acid receptor β mediates retinoic acid-induced growth arrest and apoptosis in breast cancer cells. Cell Growth Differ 1995;6:1077-1088
21. Treutin PM, Chen LI, Buetow BS, et al. Retinoic acid receptor β2 inhibition of metastasis in mouse mammary gland xenografts. Breast Cancer Res Treat 2002;72:79-88.
22. Timoshenko AV, Chakraborty C, Wagner GF, Lala PK. COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer. Br J Cancer 2006;94:1154-1163
23. Basu GD, Liang WS, Stephan DA, et al. A novel role for cyclooxygenase-2 in regulating vascular channel formation by human breast cancer cells. Breast Cancer Res 2006;8:R69.
24. Teh SH, Hill AK, Foley DA, McDermott EW, O'Higgins NJ, Young LS. COX inhibitors modulate bFGF-induced cell survival in MCF-7 breast cancer cells. J Cell Biochem 2004;91:796-807.
25. Kurie JM, Lotan R, Lee JJ, et al. Treatment of former smokers with 9-cis-retinoic acid reverses loss of retinoic acid receptor-β expression in the bronchial epithelium: results from a randomized placebo-controlled trial. J Natl Cancer Inst 2003;95:206-214 (Pubitemid 36240633)
26. Ayoub J, Jean-Francois R, Cormier Y, et al. Placebo-controlled trial of 13-cis-retinoic acid activity on retinoic acid receptor-β expression in a population at high risk: implications for chemoprevention of lung cancer. J Clin Oncol 1999;17:3546-3552 (Pubitemid 29517926)
27. Lam S, Xu X-C, Parker-Klein H, et al. Surrogate end-point biomarker analysis in a retinol chemoprevention trial in current and former smokers with bronchial dysplasia. Int J Oncol 2003;23:1607-1613
28. Alberts D, Ranger-Moore J, Einspahr J, et al. Safety and efficacy of dose-intensive oral vitamin A in subjects with sun-damaged skin. Clin Cancer Res 2004;10:1875-1880 (Pubitemid 38375542)
29. Geradts J, Chen J-Y, Russell EK, Yankaskas JR, Nieves L, Minna JD. Human lung cancer cell lines exhibit resistance to retinoic acid treatment. Cell Growth Differ 1993;4:799-809.
30. Mestre JR, Subbaramaiah K, Sacks PG, et al. Retinoids suppress epidermal growth factor-induced transcription of cyclooxygenase-2 in human oral squamous carcinoma cells. Cancer Res 1997;57:2890-2895 (Pubitemid 27315035)
31. Xu XC. COX-2 inhibitors in cancer treatment and prevention, a recent development. Anticancer Drugs 2002;13:127-137 (Pubitemid 34183641)
32. Li M, Wu X, Xu X-C. Induction of apoptosis by cyclooxygenase-2 inhibitor NS398 through a cytochrome C-dependent pathway in esophageal cancer cells. Int J Cancer 2001;93:218-223 (Pubitemid 32574278)
33. Li M, Lotan R, Levin B, Tahara E, Lippman SM, Xu XC. Aspirin induction of apoptosis in esophageal cancer: a potential for chemoprevention. Cancer Epidemiol Biomarkers Prev 2000;9:545-549 (Pubitemid 30396174)
34. Solomon SD, McMurray JJ, Pfeffer MA, et al. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 2005;352:1071-1080 (Pubitemid 40365348)
35. Chen T, Hwang H, Rose ME, Nines RG, Stoner GD. Chemopreventive properties of black raspberries in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis: down-regulation of COX-2, iNOS and c-Jun. Cancer Res 2006;66:2853-2859
36. Brown PH, Subbaramaiah K, Salmon AP, et al. Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid. Cancer Prev Res (Phila Pa) 2008;1:208-214
37. van Zandwijk N, Dalesio O, Pastorino U, de Vries N, van Tinteren H. EUROSCAN, a randomized trial of vitamin A and N-acetylcysteine in patients with head and neck cancer or lung cancer. For the European Organization for Research and Treatment of Cancer Head and Neck and Lung Cancer Cooperative Groups. J Natl Cancer Inst 2000;92:977-986
38. Lippman SM, Lee JJ, Karp DD, et al. Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer. J Natl Cancer Inst 2001;93:605-618