Perilesional changes of focal osteochondral defects in an ovine model and their relevance to human osteochondral injuries

Journal of Bone and Joint Surgery - Series B

Volumn 91, Issue 8, 2009, Pages 1110-1119

  Hepp, P ^a   Osterhoff, G ^a   Niederhagen, M ^a,b   Marquass, B ^a   Aigner, T ^a   Bader, A ^a   Josten, C ^a   Schulz, R ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE; CHONDROPATHY; CHRONIC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; JOINT BIOPSY; KNEE; KNEE INJURY; NONHUMAN; OSTEOCHONDRAL INJURY; OSTEOCHONDRITIS DISSECANS; PRIORITY JOURNAL; SHEEP;

ADOLESCENT; ADULT; ANIMALS; ARTHROSCOPY; CARTILAGE, ARTICULAR; FEMALE; HUMANS; MALE; MIDDLE AGED; OSTEOCHONDRITIS; PATELLA; SHEEP; YOUNG ADULT;

EID: 68249091542     PISSN: 0301620X     EISSN: None     Source Type: Journal    
DOI: 10.1302/0301-620X.91B8.22057     Document Type: Article

References (56)

1. Tuan RS. Skeletal tissue engineering in cartilage replacement: future perspectives and the new age of regenerative medicine. In: Hendrich C, Nöth U, Eulert J, eds. Cartilage surgery and future perspectives. Berlin: Springer, 2003:185-197
2. Steadman JR, Rodkey WG, Singleton SB, Briggs KK. Microfracture technique for full thickness chondral defects: technique and clinical results. Operat Tech Orthop 1997;7:300-304
3. Kim HK, Moran ME, Salter RB. The potential for regeneration of articular cartilage in defects created by chondral shaving and subchondral abrasion: an experimental investigation in rabbits. J Bone Joint Surg [Am] 1991;73-A:1301-1315
4. Hangody L, Kish G, Kárpati Z, et al. Mosaicplasty for the treatment of articular cartilage defects: application in clinical practice. Orthopedics 1998;21:751-756 (Pubitemid 28334555)
5. Hunziker EB. Articular cartilage repair: basic science and clinical progress: a review of the current status and prospects. Osteoarthritis Cartilage 2002;10:432-463
6. Brittberg M, Lindahl A, Nilsson A, et al. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 1994;331:889-895 (Pubitemid 24299869)
7. Reinholz GG, Lu L, Saris DB, Yaszemski MJ, O'Driscoll SW. Animal models for cartilage reconstruction. Biomaterials 2004;25:1511-1521
8. Buma P, Schreurs W, Verdonschot N. Skeletal tissue engineering: from in vitro studies to large animal models. Biomaterials 2004;25:1487-1495 (Pubitemid 38091528)
9. Munirah S, Samsudin OC, Chen HC, et al. Articular cartilage restoration in loadbearing osteochondral defects by implantation of autologous chondrocyte-fibrin constructs: an experimental study in sheep. J Bone Joint Surg [Br] 2007;89-B:1099-1109 (Pubitemid 47492809)
10. Barnewitz D, Endres M, Kruger I, et al. Treatment of articular cartilage defects in horses with polymer-based cartilage tissue engineering grafts. Biomaterials 2006;27:2882-2889 (Pubitemid 43165757)
11. Chiang H, Kuo TF, Tsai CC, et al. Repair of porcine articular cartilage defect with autologous chondrocyte transplantation. J Orthop Res 2005;23:584-593 (Pubitemid 40631330)
12. Guo X, Wang C, Zhang Y, et al. Repair of large articular cartilage defects with implants of autologous mesenchymal stem cells seeded into beta-tricalcium phosphate in a sheep model. Tissue Eng 2004;10:1818-1829 (Pubitemid 40054223)
13. Jiang CC, Chiang H, Liao CJ, et al. Repair of porcine articular cartilage defect with a biphasic osteochondral composite. J Orthop Res 2007;25:1277-1290 (Pubitemid 47523357)
14. Liu Y, Chen F, Liu W, et al. Repairing large porcine full-thickness defects of articular cartilage using autologous chondrocyte-engineered cartilage. Tissue Eng 2002;8:709-721 (Pubitemid 34857806)
15. Russlies M, Behrens P, Ehlers EM, et al. Periosteum stimulates subchondral bone densification in autologous chondrocyte transplantation in a sheep model. Cell Tissue Res 2005;319:133-142 (Pubitemid 40104644)
16. Goodrich LR, Hidaka C, Robbins PD, Evans CH, Nixon AJ. Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine model. J Bone Joint Surg [Br] 2007;89-B:672-685 (Pubitemid 46958780)
17. Saris DB, Dhert WJ, Verbout AJ. Joint homeostasis: the discrepancy between old and fresh defects in cartilage repair. J Bone Joint Surg [Br] 2003;85-B:1067-1076
18. Verbruggen G, Wittoek R, Groenboer S, et al. Osteochondral repair in synovial joints. Curr Opin Rheumatol 2007;19:265-271
19. Horas U, Pelinkovic D, Herr G, Aigner T, Schnettler R. Autologous chondrocyte implantation and osteochondral cylinder transplantation in cartilage repair of the knee joint: a prospective, comparative trial. J Bone Joint Surg [Am] 2003;85-A:185-192 (Pubitemid 36538777)
20. Knutsen G, Engebretsen L, Ludvigsen TC, et al. Autologous chondrocyte implantation compared with microfracture in the knee: a randomized trial. J Bone Joint Surg [Am] 2004;86-A:455-464 (Pubitemid 38269014)
21. Krishman SP, Skinner JA, Carrington RW, et al. Collagen-covered autologous chondrocyte implantation for osteochondritis dissecans of the knee: two- to sevenyear results. J Bone Joint Surg [Br] 2006;88-B:203-205
22. Ruano-Ravina A, Jato Diaz M. Autologous chondrocyte implantation: a systematic review. Osteoarthritis Cartilage 2006;14:47-51. (Pubitemid 43034089)
23. Wasiak J, Clar C, Villaneuva E. Autologous cartilage implantation for full thickness articular cartilage defects of the knee. Cochrane Database Syst Rev 2006;3:CD003323.
24. Strauss EJ, Goodrich LR, Chen CT, Hidaka C, Nixon AJ. Biochemical and biomechanical properties of lesion and adjacent articular cartilage after chondral defect repair in an equine model. Am J Sports Med 2005;33:1647-1653 (Pubitemid 41546737)
25. No authors listed. ETS 123 - Multilateral consultation of parties to the european convention for the protection of vertebrate animals used for experimential and other scientific purposes CONS Strasburg, 1997.
26. Green CJ, Knight J, Precious S, Simpkin S. Ketamine alone and combined with diazepam or xylaxine in laboratory animals: a 10 year experience. Lab Anim 1981;15:163-170 (Pubitemid 11073500)
27. Nowrouzian I, Schels HF, Ghodsian I, Karimi H. Evaluation of the anaesthetic properties of ketamine/xylazine/atropine combination in sheep. Vet Rec 1981;108:354-356 (Pubitemid 11116270)
28. Mama R, Wagner AE, Steffey EP, et al. Evaluation of xylazine and ketamine for total intravenous anesthesia in horses. Am J Vet Res 2005;66:3617-3629
29. Dorotka R, Windberger U, Macfelds K, et al. Repair of articular cartilage defects treated by microfracture and a three-dimensional collagen matrix. Biomaterials 2005;26:3617-3629 (Pubitemid 40038156)
30. Duda GN, Maldonado ZM, Klein P, et al. On the influence of mechanical conditions in osteochondral defect healing. J Biomech 2005;38:843-851 (Pubitemid 40248471)
31. Brittberg M, Winalski CS. Evaluation of cartilage injuries and repair. J Bone Joint Surg [Am] 2003;85-A(Suppl 2):58-69.
32. Romeis B. Mikroskopische Technik, 17th ed. Munich: Urban and Schwarzenberg, 1989.
33. Mainil-Varlet P, Aigner T, Brittberg M, et al. Histological assessment of cartilage repair: a report by the Histology Endpoint Committee of the International Cartilage Repair Society (ICRS). J Bone Joint Surg [Am] 2003;85-A(Suppl 2):45-57. (Pubitemid 36535045)
34. Rudert M. Histological evaluation of osteochondral defects: consideration of animal models with emphasis on the rabbit, experimental setup, follow-up and applied methods. Cells Tissues Organs 2002;171:229-240 (Pubitemid 34920701)
35. Mankin HJ, Dorfman H, Lippiello L, Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritis human hips. II: correlation of morphology with biochemical and metabolic data. J Bone Joint Surg [Am] 1971;53-A:523-537
36. Colwell CW Jr, D'Lima DD, Hoenecke HR, et al. In vivo changes after mechanical injury. Clin Orthop 2001;391 (Suppl):116-123
37. van der Sluijs JA, Geesink RG, van der Linden AJ, et al. The reliability of the Mankin score for osteoarthritis. J Orthop Res 1992;10:58-61.
38. Bail H, Klein P, Kolbeck S, et al. Systemic application of growth hormone enhances the early healing phase of osteochondral defects: a preliminary study in micropigs. Bone 2003;32:457-467 (Pubitemid 39665704)
39. Jackson DW, Lalor PA, Aberman HM, Simon TM. Spontaneous repair of fullthickness defects of articular cartilage in a goat model: a preliminary study. J Bone Joint Surg [Am] 2001;83-A:53-64.
40. Aroen A, Loken S, Heir S, et al. Articular cartilage lesions in 993 consecutive knee arthroscopies. Am J Sports Med 2004;32:211-215 (Pubitemid 38141444)
41. Convery FR, Akeson WH, Keown GH. The repair of large osteochondral defects: an experimental study in horses. Clin Orthop 1972;82:253-262
42. Hurtig MB, Fretz PB, Doige CE, Schnurr DL. Effects of lesion size and location on equine articular cartilage repair. Can J Vet Surg 1988;52:137-146
43. Vasara AI, Hyttinen MM, Lammi MJ, et al. Subchondral bone reaction associated with chondral defect and attempted cartilage repair in goats. Calcif Tissue Int 2004;74:107-114
44. Spahn G, Plettenberg H, Nagel H, et al. Evaluation of cartilage defects with nearinfrared spectroscopu (NIR): an ex vivo study. Med Eng Phys 2008;30:285-292 (Pubitemid 351324876)
45. Guettler JH, Demetropoulos CK, Yang KH, Jurist KA. Osteochondral defects in the human knee: influence of defect size on cartilage rim stress and load redistribution to surrounding cartilage. Am J Sports Med 2004;32:1451-1458
46. Burr DB, Schaffler MB. The involvement of subchondral mineralized tissues in osteoarthrosis: quantitative microscopic evidence. Microsc Res Tech 1997;37:343-357
47. Yang JP, Bogoch ER, Woodside TD, Hearn TC. Stiffness of trabecular bone of the tibia plateau in patients with rheumatoid arthritis of the knee. J Arthroplasty 1997;12:798-803.
48. Buckwalter JA, Mankin HJ. Articular cartilage. Part II: degeneration and osteoarthrosis, repair, regeneration, and transplantation. J Bone Joint Surg [Am] 1997;79-A:612-632
49. Goldring MB, Goldring SR. Osteoarthritis. J Cell Physiol 2007;213:626-634
50. Mastbergen SC, Marijnissen AC, Vianen ME, et al. The canine 'groove' model of osteoarthritis is more than simply the expression of surgically applied damage. Osteoarthritis Cartilage 2006;14:39-46.
51. Wei L, Svensson O, Hjerpe A. Correlation of morphologic and biochemical changes in the natural history of spontaneous osteoarthrosis in guinea pigs. Arthritis Rheum 1997;40:2075-2083 (Pubitemid 27494669)
52. Kleemann RU, Krocker D, Cedraro A, Tuischer J, Duda GN. Altered cartilage mechanics and histology in knee osteoarthritis: relation to clinical assessment (ICRS Grade). Osteoarthritis Cartilage 2005;13:958-963 (Pubitemid 41536127)
53. Matsui H,. Shimizu M, Tsuji H. Cartilage and subchondral bone interaction in osteoarthrosis of human knee joint: a histological and histomorphometric study. Microsc Res Tech 1997;37:333-342 (Pubitemid 27247061)
54. O'Driscoll SW. The healing and regeneration of articular cartilage. J Bone Joint Surg [Am] 1998;80-A:1795-1812
55. Rand JS, Ilstrup DM. Survivorship analysis of total knee arthroplasty: cumulative rates of survival of 9200 total knee arthroplasties. J Bone Joint Surg [Am] 1991;73-A:397-409.
56. Biant LC, Bentley G. Stem cells and debrided waste: two alternative sources of cells for transplantation of cartilage. J Bone Joint Surg [Br] 2007;89-B:1110-1114 (Pubitemid 47492810)