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Volumn 19, Issue 3, 2007, Pages 265-271

Osteochondral repair in synovial joints

Author keywords

Arthritis; Osteochondral repair; Tumor necrosis factor

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CYTOKINE; INFLIXIMAB; OSTEOCLAST DIFFERENTIATION FACTOR; PLACEBO; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 34247103694     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/BOR.0b013e3280be58ff     Document Type: Review
Times cited : (15)

References (63)
  • 1
    • 0032963536 scopus 로고    scopus 로고
    • Immunohistological analysis of cytokine expression in human osteoarthritic and healthy cartilage
    • Moos V, Fickert S, Muller B, et al. Immunohistological analysis of cytokine expression in human osteoarthritic and healthy cartilage. J Rheumatol 1999; 26:870-879.
    • (1999) J Rheumatol , vol.26 , pp. 870-879
    • Moos, V.1    Fickert, S.2    Muller, B.3
  • 2
    • 0024209843 scopus 로고
    • Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explants
    • Luyten FP, Hascall VC, Nissley SP, et al. Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explants. Arch Biochem Biophys 1988; 267:416-425.
    • (1988) Arch Biochem Biophys , vol.267 , pp. 416-425
    • Luyten, F.P.1    Hascall, V.C.2    Nissley, S.P.3
  • 3
    • 0029558871 scopus 로고
    • Standardization of nutrient media for isolated human articular chondrocytes in gelified agarose suspension culture
    • Verbruggen G, Malfait AM, Dewulf M, et al. Standardization of nutrient media for isolated human articular chondrocytes in gelified agarose suspension culture. Osteoarthritis Cartilage 1995; 3:249-259.
    • (1995) Osteoarthritis Cartilage , vol.3 , pp. 249-259
    • Verbruggen, G.1    Malfait, A.M.2    Dewulf, M.3
  • 4
    • 0031574479 scopus 로고    scopus 로고
    • Synergistic action of transforming growth factor-beta and insulin-like growth factor-I induces expression of type II collagen and aggrecan genes in adult human articular chondrocytes
    • Yaeger PC, Masi TL, de Ortiz JL, et al. Synergistic action of transforming growth factor-beta and insulin-like growth factor-I induces expression of type II collagen and aggrecan genes in adult human articular chondrocytes. Exp Cell Res 1997; 237:318-325.
    • (1997) Exp Cell Res , vol.237 , pp. 318-325
    • Yaeger, P.C.1    Masi, T.L.2    de Ortiz, J.L.3
  • 6
    • 0022383463 scopus 로고
    • Pig IL-1 (catabolin) induces resorption of cartilage proteoglycan and prevents synthesis of proteoglycan and collagen
    • Tyler JA, Saklatvala J. Pig IL-1 (catabolin) induces resorption of cartilage proteoglycan and prevents synthesis of proteoglycan and collagen. Br J Rheumatol 1985; 24 (Suppl 1):150-155.
    • (1985) Br J Rheumatol , vol.24 , Issue.SUPPL. 1 , pp. 150-155
    • Tyler, J.A.1    Saklatvala, J.2
  • 7
    • 0023037402 scopus 로고
    • Identification of a common class of high affinity receptors for both types of interleulin-1 on connective tissue cells
    • Bird TA, Saklatvala J. Identification of a common class of high affinity receptors for both types of interleulin-1 on connective tissue cells. Nature 1986; 324:263-266.
    • (1986) Nature , vol.324 , pp. 263-266
    • Bird, T.A.1    Saklatvala, J.2
  • 8
    • 0027181936 scopus 로고
    • Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4
    • Colotta F, Re F, MuzioM, et al. Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4. Science 1993; 261:472-475.
    • (1993) Science , vol.261 , pp. 472-475
    • Colotta, F.1    Re, F.2    MuzioM3
  • 9
    • 0038328889 scopus 로고    scopus 로고
    • IGF-1-induced IL-1RII overrules IL-1 activity and controls the homeostasis of the extracellular matrix of cartilage
    • Wang J, Elewaut D, Veys EM, Verbruggen G. IGF-1-induced IL-1RII overrules IL-1 activity and controls the homeostasis of the extracellular matrix of cartilage. Arthritis Rheum 2003; 48:1281-1291.
    • (2003) Arthritis Rheum , vol.48 , pp. 1281-1291
    • Wang, J.1    Elewaut, D.2    Veys, E.M.3    Verbruggen, G.4
  • 10
    • 0024338070 scopus 로고
    • Insulin-like growth factor 1 can decrease degradation and promote synthesis of proteoglycan in cartilage exposed to cytokines
    • Tyler JA. Insulin-like growth factor 1 can decrease degradation and promote synthesis of proteoglycan in cartilage exposed to cytokines. Biochem J 1989; 260:543-548.
    • (1989) Biochem J , vol.260 , pp. 543-548
    • Tyler, J.A.1
  • 11
    • 0023857232 scopus 로고
    • Growth hormone dependent stimulation of osteoblast-like cells in serum-free cultures via local synthesis of insulin-like growth factor I
    • Ernst M, Froesch ER. Growth hormone dependent stimulation of osteoblast-like cells in serum-free cultures via local synthesis of insulin-like growth factor I. Biochem Biophys Res Commun 1988; 151:142-147.
    • (1988) Biochem Biophys Res Commun , vol.151 , pp. 142-147
    • Ernst, M.1    Froesch, E.R.2
  • 12
    • 0027414899 scopus 로고
    • Differential effects of transforming growth factor-beta 1 and bone morphogenetic protein 4 on gene expression and differentiated function of preosteoblasts
    • Zhou H, Hammonds RG Jr, Findlay DM, et al. Differential effects of transforming growth factor-beta 1 and bone morphogenetic protein 4 on gene expression and differentiated function of preosteoblasts. J Cell Physiol 1993; 155:112-119.
    • (1993) J Cell Physiol , vol.155 , pp. 112-119
    • Zhou, H.1    Hammonds Jr, R.G.2    Findlay, D.M.3
  • 13
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
    • Yasuda H, Shima N, Nakagawa N, et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 1998; 95:3597-3602.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3597-3602
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3
  • 14
    • 0031005576 scopus 로고    scopus 로고
    • Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
    • Simonet WS, Lacey DL, Dunstan CR, et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 1997; 89:309-319.
    • (1997) Cell , vol.89 , pp. 309-319
    • Simonet, W.S.1    Lacey, D.L.2    Dunstan, C.R.3
  • 15
    • 0024041998 scopus 로고
    • Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats
    • Guler HP, Zapf J, Scheiwiller E, Froesch ER. Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats. Proc Natl Acad Sci USA 1988; 85:4889-4893.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4889-4893
    • Guler, H.P.1    Zapf, J.2    Scheiwiller, E.3    Froesch, E.R.4
  • 16
    • 0033848680 scopus 로고    scopus 로고
    • Importance of membrane- or matrix-associated forms of M-CSF and RANKL/ODF in osteoclastogenesis supported by SaOS-4/3 cells expressing recombinant PTH/PTHrP receptors
    • Itoh K, Udagawa N, Matsuzaki K, et al. Importance of membrane- or matrix-associated forms of M-CSF and RANKL/ODF in osteoclastogenesis supported by SaOS-4/3 cells expressing recombinant PTH/PTHrP receptors. J Bone Miner Res 2000; 15:1766-1775.
    • (2000) J Bone Miner Res , vol.15 , pp. 1766-1775
    • Itoh, K.1    Udagawa, N.2    Matsuzaki, K.3
  • 17
    • 0021962820 scopus 로고
    • The effect of calcium-regulating hormones and prostaglandins on bone resorption by osteoclasts disaggregated from neonatal rabbit bones
    • Chambers TJ, McSheely PM, Thomson BM, Fuller K. The effect of calcium-regulating hormones and prostaglandins on bone resorption by osteoclasts disaggregated from neonatal rabbit bones. Endocrinology 1985; 116:234-239.
    • (1985) Endocrinology , vol.116 , pp. 234-239
    • Chambers, T.J.1    McSheely, P.M.2    Thomson, B.M.3    Fuller, K.4
  • 18
    • 0028354091 scopus 로고
    • Comparative and combined effects of interleukin 6, interleukin 1 beta, and tumor necrosis factor alpha on proteoglycan metabolism of human articular chondrocytes cultured in agarose
    • Malfait AM, Verbruggen G, Veys EM, et al. Comparative and combined effects of interleukin 6, interleukin 1 beta, and tumor necrosis factor alpha on proteoglycan metabolism of human articular chondrocytes cultured in agarose. J Rheumatol 1994; 21:314-320.
    • (1994) J Rheumatol , vol.21 , pp. 314-320
    • Malfait, A.M.1    Verbruggen, G.2    Veys, E.M.3
  • 19
    • 8444234314 scopus 로고    scopus 로고
    • Role of NF-kappaB transcription factors in antiinflammatory and proinflammatory actions of mechanical signals
    • Agarwal S, Deschner J, Long P, et al. Role of NF-kappaB transcription factors in antiinflammatory and proinflammatory actions of mechanical signals. Arthritis Rheum 2004; 50:3541-3548.
    • (2004) Arthritis Rheum , vol.50 , pp. 3541-3548
    • Agarwal, S.1    Deschner, J.2    Long, P.3
  • 20
    • 0036033243 scopus 로고    scopus 로고
    • Hydrostatic pressure induces apoptosis in human chondrocytes from osteoarthritic cartilage through up-regulation of tumor necrosis factor-alpha, inducible nitric oxide synthase, p53, c-myc, and bax-alpha, and suppression of bcl-2
    • Islam N, Haqqi TM, Jepsen KJ, et al. Hydrostatic pressure induces apoptosis in human chondrocytes from osteoarthritic cartilage through up-regulation of tumor necrosis factor-alpha, inducible nitric oxide synthase, p53, c-myc, and bax-alpha, and suppression of bcl-2. J Cell Biochem 2002; 87:266-278.
    • (2002) J Cell Biochem , vol.87 , pp. 266-278
    • Islam, N.1    Haqqi, T.M.2    Jepsen, K.J.3
  • 22
    • 0034092320 scopus 로고    scopus 로고
    • Autocrine regulation of collagenase 3 (matrix metalloproteinase 13) during osteoarthritis
    • Shlopov BV, Gumanovskaya ML, Hasty KA. Autocrine regulation of collagenase 3 (matrix metalloproteinase 13) during osteoarthritis. Arthritis Rheum 2000; 43:195-205.
    • (2000) Arthritis Rheum , vol.43 , pp. 195-205
    • Shlopov, B.V.1    Gumanovskaya, M.L.2    Hasty, K.A.3
  • 23
    • 0242606952 scopus 로고    scopus 로고
    • Homeostasis of the extracellular matrix of normal and osteoarthritic human articular cartilage chondrocytes in vitro
    • Wang J, Verdonk P, Elewaut D, et al. Homeostasis of the extracellular matrix of normal and osteoarthritic human articular cartilage chondrocytes in vitro. Osteoarthritis Cartilage 2003; 11:801-809.
    • (2003) Osteoarthritis Cartilage , vol.11 , pp. 801-809
    • Wang, J.1    Verdonk, P.2    Elewaut, D.3
  • 24
    • 0020682296 scopus 로고
    • Collagenase and collagenolytic activity in human osteoarthritic cartilage
    • Pelletier JP, Martel-Pelletier J, Howell DS, et al. Collagenase and collagenolytic activity in human osteoarthritic cartilage. Arthritis Rheum 1983; 26:63-68.
    • (1983) Arthritis Rheum , vol.26 , pp. 63-68
    • Pelletier, J.P.1    Martel-Pelletier, J.2    Howell, D.S.3
  • 25
    • 0026538791 scopus 로고
    • Upregulation of insulin-like growth factor I gene expression in the lesions of osteoarthritic human articular cartilage
    • Middleton JF, Tyler JA. Upregulation of insulin-like growth factor I gene expression in the lesions of osteoarthritic human articular cartilage. Ann Rheum Dis 1992; 51:440-447.
    • (1992) Ann Rheum Dis , vol.51 , pp. 440-447
    • Middleton, J.F.1    Tyler, J.A.2
  • 26
    • 0033105652 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide causes rapid shedding, followed by inhibition of mRNA expression, of the IL-1 type II receptor, with concomitant up-regulation of the type I receptor and induction of incompletely spliced transcripts
    • Penton-Rol G, Orlando S, Polentarutti N, et al. Bacterial lipopolysaccharide causes rapid shedding, followed by inhibition of mRNA expression, of the IL-1 type II receptor, with concomitant up-regulation of the type I receptor and induction of incompletely spliced transcripts. Immunology 1999; 162:2931-2938.
    • (1999) Immunology , vol.162 , pp. 2931-2938
    • Penton-Rol, G.1    Orlando, S.2    Polentarutti, N.3
  • 27
    • 0024314554 scopus 로고
    • Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
    • Brennan FM, Chantry D, Jackson A, et al. Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet 1989; 2:244-247.
    • (1989) Lancet , vol.2 , pp. 244-247
    • Brennan, F.M.1    Chantry, D.2    Jackson, A.3
  • 28
    • 0036172368 scopus 로고    scopus 로고
    • Involvement of receptor activator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis
    • Romas E, Gillespie MT, Martin TJ. Involvement of receptor activator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis. Bone 2002; 30:340-346.
    • (2002) Bone , vol.30 , pp. 340-346
    • Romas, E.1    Gillespie, M.T.2    Martin, T.J.3
  • 29
    • 0034677177 scopus 로고    scopus 로고
    • Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction
    • Kobayashi K, Takahashi K, Jimi E, et al. Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med 2000; 191:275-285.
    • (2000) J Exp Med , vol.191 , pp. 275-285
    • Kobayashi, K.1    Takahashi, K.2    Jimi, E.3
  • 30
    • 0035043292 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha cooperates with receptor activator of nuclear factor kappaB ligand in generation of osteoclasts in stromal cell-depleted rat bone marrow cell culture
    • Komine M, Kukita A, Kukita T, et al. Tumor necrosis factor-alpha cooperates with receptor activator of nuclear factor kappaB ligand in generation of osteoclasts in stromal cell-depleted rat bone marrow cell culture. Bone 2001; 28:474-483.
    • (2001) Bone , vol.28 , pp. 474-483
    • Komine, M.1    Kukita, A.2    Kukita, T.3
  • 31
    • 14944371405 scopus 로고    scopus 로고
    • IL-1 mediates TNF-induced osteoclastogenesis
    • Wei S, Kitaura H, Zhou P, et al. IL-1 mediates TNF-induced osteoclastogenesis. J Clin Invest 2005; 115:282-290.
    • (2005) J Clin Invest , vol.115 , pp. 282-290
    • Wei, S.1    Kitaura, H.2    Zhou, P.3
  • 32
    • 0032588998 scopus 로고    scopus 로고
    • Interleukin-1 beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells
    • Hofbauer LC, Lacey DL, Dunstan CR, et al. Interleukin-1 beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells. Bone 1999; 25:255-259.
    • (1999) Bone , vol.25 , pp. 255-259
    • Hofbauer, L.C.1    Lacey, D.L.2    Dunstan, C.R.3
  • 33
    • 0035808458 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways
    • Zhang YH, Heulsmann A, Tondravi MM, et al. Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways. J Biol Chem 2001; 276:563-568.
    • (2001) J Biol Chem , vol.276 , pp. 563-568
    • Zhang, Y.H.1    Heulsmann, A.2    Tondravi, M.M.3
  • 34
    • 11144282704 scopus 로고    scopus 로고
    • TNF-alpha expression is transcriptionally regulated by RANK ligand
    • Zou W, Amcheslavsky A, Takeshita S, et al. TNF-alpha expression is transcriptionally regulated by RANK ligand. J Cell Physiol 2005; 202:371-378.
    • (2005) J Cell Physiol , vol.202 , pp. 371-378
    • Zou, W.1    Amcheslavsky, A.2    Takeshita, S.3
  • 35
    • 0025767355 scopus 로고
    • Differential effects of insulin-like growth factors I and II on growth, differentiation and glucoregulation in differentiating chondrocyte cells in culture
    • Bhaumick B, Bala RM. Differential effects of insulin-like growth factors I and II on growth, differentiation and glucoregulation in differentiating chondrocyte cells in culture. Acta Endocrinol (Copenh) 1991; 125:201-211.
    • (1991) Acta Endocrinol (Copenh) , vol.125 , pp. 201-211
    • Bhaumick, B.1    Bala, R.M.2
  • 36
    • 0022639704 scopus 로고    scopus 로고
    • D'Ercole AL, Hill DJ, Strain AJ, Underwood LE. Tissue and plasma somatomedin-C/insulin-like growth factor I concentrations in the human fetus during the first half of gestation. Pediatr Res 1986; 20:253-255.
    • D'Ercole AL, Hill DJ, Strain AJ, Underwood LE. Tissue and plasma somatomedin-C/insulin-like growth factor I concentrations in the human fetus during the first half of gestation. Pediatr Res 1986; 20:253-255.
  • 37
    • 0022355552 scopus 로고
    • Characterization of a specific insulin-like growth factor-I/somatomedin-C receptor on high density, primary monolayer cultures of bovine articular chondrocytes: Regulation of receptor concentration by somatomedin, insulin and growth hormone
    • Watanabe N, Rosenfeld RG, Hintz RL, et al. Characterization of a specific insulin-like growth factor-I/somatomedin-C receptor on high density, primary monolayer cultures of bovine articular chondrocytes: regulation of receptor concentration by somatomedin, insulin and growth hormone. J Endocrinol 1985; 107:275-283.
    • (1985) J Endocrinol , vol.107 , pp. 275-283
    • Watanabe, N.1    Rosenfeld, R.G.2    Hintz, R.L.3
  • 38
    • 0023038743 scopus 로고
    • Stimulation of proteoglycan synthesis by serum and insulin-like growth factor-1 in cultured bovine articular cartilage
    • McQuillan DL, Handley CJ, Campbell MA, et al. Stimulation of proteoglycan synthesis by serum and insulin-like growth factor-1 in cultured bovine articular cartilage. Biochem J 1986; 240:423-430.
    • (1986) Biochem J , vol.240 , pp. 423-430
    • McQuillan, D.L.1    Handley, C.J.2    Campbell, M.A.3
  • 39
    • 0034731378 scopus 로고    scopus 로고
    • The first two N-terminal immunoglobulin-like domains of soluble human IL-1 receptor type II are sufficient to bind and neutralize IL-1beta
    • Kollewe C, Neumann D, Martin MU. The first two N-terminal immunoglobulin-like domains of soluble human IL-1 receptor type II are sufficient to bind and neutralize IL-1beta. FEBS Lett 2000; 487:189-193.
    • (2000) FEBS Lett , vol.487 , pp. 189-193
    • Kollewe, C.1    Neumann, D.2    Martin, M.U.3
  • 40
    • 0031918202 scopus 로고    scopus 로고
    • Martel-Pelletier J, Di Battista JA, Lajeunesse D, Pelletier JP. IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis. Inflamm Res 1998; 47:90-100.
    • Martel-Pelletier J, Di Battista JA, Lajeunesse D, Pelletier JP. IGF/IGFBP axis in cartilage and bone in osteoarthritis pathogenesis. Inflamm Res 1998; 47:90-100.
  • 41
    • 0029088361 scopus 로고
    • Interleukin-1 and tumor necrosis factor-alpha increase insulin-like growth factor-binding protein-3 (IGFBP-3) production and IGFBP-3 protease activity in human articular chondrocytes
    • Olney RC, Wilson DM, Mohtai M, et al. Interleukin-1 and tumor necrosis factor-alpha increase insulin-like growth factor-binding protein-3 (IGFBP-3) production and IGFBP-3 protease activity in human articular chondrocytes. J Endocrinol 1995; 146:279-286.
    • (1995) J Endocrinol , vol.146 , pp. 279-286
    • Olney, R.C.1    Wilson, D.M.2    Mohtai, M.3
  • 42
    • 0021238506 scopus 로고
    • In vivo and in vitro stimulation of chondrocyte biosynthetic activity in early experimental osteoarthritis
    • Sandy JD, Adams ME, Billingham ME, et al. In vivo and in vitro stimulation of chondrocyte biosynthetic activity in early experimental osteoarthritis. Arthritis Rheum 1984; 27:388-397.
    • (1984) Arthritis Rheum , vol.27 , pp. 388-397
    • Sandy, J.D.1    Adams, M.E.2    Billingham, M.E.3
  • 43
    • 0021796612 scopus 로고
    • Structure of newly synthesised (35S)-proteoglycans and (35S)-proteoglycan turnover products of cartilage explant cultures from dogs with experimental osteoarthritis
    • Carney SL, Billingham ME, Muir H, Sandy JD. Structure of newly synthesised (35S)-proteoglycans and (35S)-proteoglycan turnover products of cartilage explant cultures from dogs with experimental osteoarthritis. J Orthop Res 1985; 3:140-147.
    • (1985) J Orthop Res , vol.3 , pp. 140-147
    • Carney, S.L.1    Billingham, M.E.2    Muir, H.3    Sandy, J.D.4
  • 44
    • 0021710204 scopus 로고
    • Demonstration of increased proteoglycan turnover in cartilage explants from dogs with experimental osteoarthritis
    • Carney SL, Billingham ME, Muir H, Sandy JD. Demonstration of increased proteoglycan turnover in cartilage explants from dogs with experimental osteoarthritis. J Orthop Res 1984; 2:201-206.
    • (1984) J Orthop Res , vol.2 , pp. 201-206
    • Carney, S.L.1    Billingham, M.E.2    Muir, H.3    Sandy, J.D.4
  • 46
    • 0024797336 scopus 로고
    • Changes in the sedimentation profile of proteoglycan aggregates in early experimental canine osteoarthritis
    • Manicourt DH, Thonar EJ, Pita JC, Howell DS. Changes in the sedimentation profile of proteoglycan aggregates in early experimental canine osteoarthritis. Connect Tissue Res 1989; 23:33-50.
    • (1989) Connect Tissue Res , vol.23 , pp. 33-50
    • Manicourt, D.H.1    Thonar, E.J.2    Pita, J.C.3    Howell, D.S.4
  • 47
    • 0022441214 scopus 로고
    • Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage
    • Saklatvala J. Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature 1986; 322:547-549.
    • (1986) Nature , vol.322 , pp. 547-549
    • Saklatvala, J.1
  • 48
    • 0018835865 scopus 로고
    • Antigen-induced arthritis. Studies on the inhibition of proteoglycan synthesis observed in articular cartilage during short-term joint inflammation
    • Sandy JD, Lowther DA, Brown HL. Antigen-induced arthritis. Studies on the inhibition of proteoglycan synthesis observed in articular cartilage during short-term joint inflammation. Arthritis Rheum 1980; 23:433-447.
    • (1980) Arthritis Rheum , vol.23 , pp. 433-447
    • Sandy, J.D.1    Lowther, D.A.2    Brown, H.L.3
  • 49
    • 0024348974 scopus 로고
    • Chondrocyte nonresponsiveness to insulin-like growth factor 1 in experimental arthritis
    • Schalkwijk J, Joosten LA, van den Berg WB, van de Putte LB. Chondrocyte nonresponsiveness to insulin-like growth factor 1 in experimental arthritis. Arthritis Rheum 1989; 32:894-900.
    • (1989) Arthritis Rheum , vol.32 , pp. 894-900
    • Schalkwijk, J.1    Joosten, L.A.2    van den Berg, W.B.3    van de Putte, L.B.4
  • 50
    • 0028936336 scopus 로고
    • Detection of insulin-like growth factor I and II in synovial tissue specimens of patients with rheumatoid arthritis and osteoarthritis by in situ hybridization
    • Keyszer GM, Heer AH, Kriegsmann J, et al. Detection of insulin-like growth factor I and II in synovial tissue specimens of patients with rheumatoid arthritis and osteoarthritis by in situ hybridization. J Rheumatol 1995; 22:275-281.
    • (1995) J Rheumatol , vol.22 , pp. 275-281
    • Keyszer, G.M.1    Heer, A.H.2    Kriegsmann, J.3
  • 51
    • 0030026363 scopus 로고    scopus 로고
    • Identification and characterization of insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), and IGFBP proteases in human synovial fluid
    • Matsumoto T, Gargoski SE, Iwasaki K, Rosenfeld RG. Identification and characterization of insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), and IGFBP proteases in human synovial fluid. J Clin Endocrinol Metab 1996; 81:150-155.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 150-155
    • Matsumoto, T.1    Gargoski, S.E.2    Iwasaki, K.3    Rosenfeld, R.G.4
  • 52
    • 0031013697 scopus 로고    scopus 로고
    • Dynamic expression of transforming growth factor-betas (TGF-beta) and their type I and type II receptors in the synovial tissue of arthritic rats
    • Mussener A, Funa K, Kleinau S, Klareskog L. Dynamic expression of transforming growth factor-betas (TGF-beta) and their type I and type II receptors in the synovial tissue of arthritic rats. Clin Exp Immunol 1997; 107:112-119.
    • (1997) Clin Exp Immunol , vol.107 , pp. 112-119
    • Mussener, A.1    Funa, K.2    Kleinau, S.3    Klareskog, L.4
  • 53
    • 0030915894 scopus 로고    scopus 로고
    • Elevated levels of insulin-like growth factor (IGF) binding protein-3 in rheumatoid arthritis synovial fluid inhibit stimulation by IGF-I of articular chondrocyte proteoglycan synthesis
    • Neidel J, Blum WF, Schaeffer HJ, et al. Elevated levels of insulin-like growth factor (IGF) binding protein-3 in rheumatoid arthritis synovial fluid inhibit stimulation by IGF-I of articular chondrocyte proteoglycan synthesis. Rheumatol Int 1997; 17:29-37.
    • (1997) Rheumatol Int , vol.17 , pp. 29-37
    • Neidel, J.1    Blum, W.F.2    Schaeffer, H.J.3
  • 54
    • 0023850683 scopus 로고
    • Effects of synovial fluid and synovial fluid cells on chondrocyte metabolism in short term tissue culture
    • Nuver-Zwart I, Schalkwijk J, Joosten LA, et al. Effects of synovial fluid and synovial fluid cells on chondrocyte metabolism in short term tissue culture. J Rheumatol 1988; 15:210-216.
    • (1988) J Rheumatol , vol.15 , pp. 210-216
    • Nuver-Zwart, I.1    Schalkwijk, J.2    Joosten, L.A.3
  • 55
    • 0023815126 scopus 로고
    • The influence of synovial fluids from patients with rheumatic diseases on chick embryo fibroblasts
    • Partsch G, Petera P, Dunky A, et al. The influence of synovial fluids from patients with rheumatic diseases on chick embryo fibroblasts. Int J Tissue React 1988; 10:67-77.
    • (1988) Int J Tissue React , vol.10 , pp. 67-77
    • Partsch, G.1    Petera, P.2    Dunky, A.3
  • 56
    • 0030041071 scopus 로고    scopus 로고
    • Numerical scoring systems for the anatomic evolution of osteoarthritis of the finger joints
    • Verbruggen G, Veys EM. Numerical scoring systems for the anatomic evolution of osteoarthritis of the finger joints. Arthritis Rheum 1996; 39:308-320.
    • (1996) Arthritis Rheum , vol.39 , pp. 308-320
    • Verbruggen, G.1    Veys, E.M.2
  • 57
    • 0034735842 scopus 로고    scopus 로고
    • Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group
    • Lipsky PE, van der Heijde DM, St Clair EW, et al. Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N Engl J Med 2000; 343:1594-1602.
    • (2000) N Engl J Med , vol.343 , pp. 1594-1602
    • Lipsky, P.E.1    van der Heijde, D.M.2    St Clair, E.W.3
  • 58
    • 33745593028 scopus 로고    scopus 로고
    • Bone metabolism changes during anti-TNF-alpha therapy in patients with active rheumatoid arthritis
    • Seriolo B, Paolino S, Sulli A, et al. Bone metabolism changes during anti-TNF-alpha therapy in patients with active rheumatoid arthritis. Ann N Y Acad Sci 2006; 1069:420-427.
    • (2006) Ann N Y Acad Sci , vol.1069 , pp. 420-427
    • Seriolo, B.1    Paolino, S.2    Sulli, A.3
  • 59
    • 8444239359 scopus 로고    scopus 로고
    • Active-controlled study of patients receiving Infliximab for the treatment of rheumatoid arthritis of early onset Study Group. Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: A randomized, controlled trial
    • St Clair EW, Van Der Heijde DM, Smolen JS, et al., Active-controlled study of patients receiving Infliximab for the treatment of rheumatoid arthritis of early onset Study Group. Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial. Arthritis Rheum 2004; 50:3432-3443.
    • (2004) Arthritis Rheum , vol.50 , pp. 3432-3443
    • St Clair, E.W.1    Van Der Heijde, D.M.2    Smolen, J.S.3
  • 60
    • 33644895018 scopus 로고    scopus 로고
    • Active-controlled study of patients receiving Infliximab for the treatment of rheumatoid arthritis of early onset (ASPIRE) Study Group. Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: Results from the ASPIRE trial
    • Smolen JS, Van Der Heijde DM, St Clair EW, et al., Active-controlled study of patients receiving Infliximab for the treatment of rheumatoid arthritis of early onset (ASPIRE) Study Group. Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: results from the ASPIRE trial. Arthritis Rheum 2006; 54:702-710.
    • (2006) Arthritis Rheum , vol.54 , pp. 702-710
    • Smolen, J.S.1    Van Der Heijde, D.M.2    St Clair, E.W.3
  • 61
    • 33646365588 scopus 로고    scopus 로고
    • TEMPO Study Investigators. Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis: Two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trial
    • Van der Heijde D, Klareskog L, Rodriguez-Valverde V, et al., TEMPO Study Investigators. Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis: two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trial. Arthritis Rheum 2006; 54:1063-1074.
    • (2006) Arthritis Rheum , vol.54 , pp. 1063-1074
    • Van der Heijde, D.1    Klareskog, L.2    Rodriguez-Valverde, V.3
  • 62
    • 33847077596 scopus 로고    scopus 로고
    • Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondyloarthritis
    • Lories RJ, Derese I, de Bari C, Luyten FP. Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondyloarthritis. Arthritis Rheum 2007; 56:489-497.
    • (2007) Arthritis Rheum , vol.56 , pp. 489-497
    • Lories, R.J.1    Derese, I.2    de Bari, C.3    Luyten, F.P.4
  • 63
    • 0036183028 scopus 로고    scopus 로고
    • Repeated infusions of infliximab, a chimeric anti-TNF alpha monoclonal antibody, in patients with active spondyloarthropathy: One year follow up
    • Kruithof E, Van den Bosch F, Baeten D, et al. Repeated infusions of infliximab, a chimeric anti-TNF alpha monoclonal antibody, in patients with active spondyloarthropathy: one year follow up. Ann Rheum Dis 2002; 61:207-212.
    • (2002) Ann Rheum Dis , vol.61 , pp. 207-212
    • Kruithof, E.1    Van den Bosch, F.2    Baeten, D.3


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