-
1
-
-
27644549042
-
State of the art: IBD therapy and clinical trials in IBD
-
Isaacs, K. L.; Lewis, J. D.; Sandborn, W. J.; Sands, B. E.; Targan, S. R. State of the art: IBD therapy and clinical trials in IBD. Inflammatory Bowel Dis. 2005, S3-12.
-
(2005)
Inflammatory Bowel Dis.
-
-
Isaacs, K.L.1
Lewis, J.D.2
Sandborn, W.J.3
Sands, B.E.4
Targan, S.R.5
-
2
-
-
84891456522
-
-
Springer: New York
-
Targan, S. R.; Shanahan, F.; Karp, L. C. Inflammatory Bowel Disease: From Bench to Bedside, 2nd ed.; Springer: New York, 2005; p 903.
-
(2005)
Inflammatory Bowel Disease: From Bench to Bedside, 2nd Ed.
, pp. 903
-
-
Targan, S.R.1
Shanahan, F.2
Karp, L.C.3
-
3
-
-
4344702394
-
Recent advances in biological therapy for inflammatory bowel disease
-
Kurtovic, J.; Segal, I. Recent advances in biological therapy for inflammatory bowel disease. Trop. Gastroenterol. 2004, 25, 9-14.
-
(2004)
Trop. Gastroenterol.
, vol.25
, pp. 9-14
-
-
Kurtovic, J.1
Segal, I.2
-
4
-
-
0142187683
-
Biological therapy in IBD: Anti-tumor necrosis factor-alpha and others
-
DOI 10.1159/000073249
-
Scholmerich, J.; Huber, G. Biological therapy in IBD. Anti-tumor necrosis factor-alpha and others. Dig. Dis. 2003, 21, 180-191. (Pubitemid 37323495)
-
(2003)
Digestive Diseases
, vol.21
, Issue.2
, pp. 180-191
-
-
Scholmerich, J.1
Huber, G.2
-
5
-
-
33749038012
-
Current limitations of IBD treatment: Where do we go from here?
-
DOI 10.1196/annals.1326.032, Inflammatory Bowel Disease: Genetics, Barrier Function, Immunologic Mechanisms, and Microbial Pathways
-
Targan, S. R. Current limitations of IBD treatment: where do we go from here? Ann. N.Y. Acad. Sci. 2006, 1072, 1-8. (Pubitemid 44448438)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1072
, pp. 1-8
-
-
Targan, S.R.1
-
6
-
-
0036230391
-
New steroids and new salicylates in inflammatory bowel disease: A critical appraisal
-
Campieri, M. New steroids and new salicylates in inflammatory bowel disease: a critical appraisal. Gut 2002, 50, III43-III46. (Pubitemid 34413562)
-
(2002)
Gut
, vol.50
, Issue.SUPPL. 3
-
-
Campieri, M.1
-
7
-
-
40149093576
-
Review article: Evolving concepts in treatment and disease modification in ulcerative colitis
-
Hanauer, S. B. Review article: evolving concepts in treatment and disease modification in ulcerative colitis. Aliment. Pharmacol. Ther. 2008, 27, 15-21.
-
(2008)
Aliment. Pharmacol. Ther.
, vol.27
, pp. 15-21
-
-
Hanauer, S.B.1
-
8
-
-
28044454331
-
Novel drug delivery strategies for the treatment of inflammatory bowel disease
-
DOI 10.1517/17425247.2.3.451
-
Kesisoglou, F.; Zimmermann, E. M. Novel drug delivery strategies for the treatment of inflammatory bowel disease. Expert Opin. Drug Delivery 2005, 2, 451-463. (Pubitemid 41683221)
-
(2005)
Expert Opinion on Drug Delivery
, vol.2
, Issue.3
, pp. 451-463
-
-
Kesisoglou, F.1
Zimmermann, E.M.2
-
10
-
-
0034714188
-
Treatment of murine colitis by Lactococcus lactis secreting interleukin-10
-
DOI 10.1126/science.289.5483.1352
-
Steidler, L.; Hans, W.; Schotte, L.; Neirynck, S.; Obermeier, F.; Falk, W.; Fiers, W.; Remaut, E. Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. Science 2000, 289, 1352-1355. (Pubitemid 30656052)
-
(2000)
Science
, vol.289
, Issue.5483
, pp. 1352-1355
-
-
Steidler, L.1
Hans, W.2
Schotte, L.3
Neirynck, S.4
Obermeier, F.5
Falk, W.6
Fiers, W.7
Remaut, E.8
-
11
-
-
33745069019
-
Local treatment of experimental colitis in the rat by negatively charged liposomes of catalase, TMN and SOD
-
DOI 10.1080/10611860600648429, PII N45877633586
-
Jubeh, T. T.; Nadler-Milbauer, M.; Barenholz, Y.; Rubinstein, A. Local treatment of experimental colitis in the rat by negatively charged liposomes of catalase, TMN and SOD. J. Drug Targeting 2006, 14, 155-163. (Pubitemid 43878824)
-
(2006)
Journal of Drug Targeting
, vol.14
, Issue.3
, pp. 155-163
-
-
Jubeh, T.T.1
Nadler-Milbauer, M.2
Barenholz, Y.3
Rubinstein, A.4
-
12
-
-
1542406587
-
Differential adhesion of normal and inflamed rat colonic mucosa by charged liposomes
-
DOI 10.1023/B:PHAM.0000019298.29561.cd
-
Jubeh, T. T.; Barenholz, Y.; Rubinstein, A. Differential adhesion of normal and inflamed rat colonic mucosa by charged liposomes. Pharm. Res. 2004, 21, 447-453. (Pubitemid 38338980)
-
(2004)
Pharmaceutical Research
, vol.21
, Issue.3
, pp. 447-453
-
-
Jubeh, T.T.1
Barenholz, Y.2
Rubinstein, A.3
-
13
-
-
0035084176
-
Intestinal luminal pH in inflammatory bowel disease: Possible determinants and implications for therapy with aminosalicylates and other drugs
-
Nugent, S. G.; Kumar, D.; Rampton, D. S.; Evans, D. F. Intestinal luminal pH in inflammatory bowel disease: possible determinants and implications for therapy with aminosalicylates and other drugs. Gut 2001, 48, 571-577
-
(2001)
Gut
, vol.48
, pp. 571-577
-
-
Nugent, S.G.1
Kumar, D.2
Rampton, D.S.3
Evans, D.F.4
-
14
-
-
0032999413
-
Intraluminal pH of the human gastrointestinal tract
-
Fallingborg, J. Intraluminal pH of the human gastrointestinal tract. Dan. Med. Bull. 1999, 46, 183-196
-
(1999)
Dan. Med. Bull.
, vol.46
, pp. 183-196
-
-
Fallingborg, J.1
-
15
-
-
0027490263
-
Very low intraluminal colonic pH in patients with active ulcerative colitis
-
DOI 10.1007/BF01297074
-
Fallingborg, J.; Christensen, L. A.; Jacobsen, B. A.; Rasmussen, S. N. Very low intraluminal colonic pH in patients with active ulcerative colitis. Dig. Dis. Sci. 1993, 38, 1989-1993 (Pubitemid 23336560)
-
(1993)
Digestive Diseases and Sciences
, vol.38
, Issue.11
, pp. 1989-1993
-
-
Fallingborg, J.1
Christensen, L.A.2
Jacobsen, B.A.3
Rasmussen, S.N.4
-
16
-
-
0034020873
-
Secretion and tissue content of eosinophil cationic protein in Crohn's disease
-
Winterkamp, S.; Raithel, M.; Hahn, E. G. Secretion and tissue content of eosinophil cationic protein in Crohn's disease. J. Clin. Gastroenterol. 2000, 30, 170-175.
-
(2000)
J. Clin. Gastroenterol.
, vol.30
, pp. 170-175
-
-
Winterkamp, S.1
Raithel, M.2
Hahn, E.G.3
-
17
-
-
28144450660
-
Eosinophil granulocytes are activated during the remission phase of ulcerative colitis
-
DOI 10.1136/gut.2005.066423
-
Lampinen, M.; Ronnblom, A.; Amin, K.; Kristjansson, G.; Rorsman, F.; Sangfelt, P.; Safsten, B.; Wagner, M.; Wanders, A.; Winqvist, O.; Carlson, M. Eosinophil granulocytes are activated during the remission phase of ulcerative colitis. Gut 2005, 54, 1714-1720 (Pubitemid 41697669)
-
(2005)
Gut
, vol.54
, Issue.12
, pp. 1714-1720
-
-
Lampinen, M.1
Ronnblom, A.2
Amin, K.3
Kristjansson, G.4
Rorsman, F.5
Sangfelt, P.6
Safsten, B.7
Wagner, M.8
Wanders, A.9
Winqvist, O.10
Carlson, M.11
-
18
-
-
0030028796
-
Inflammatory bowel disease is associated with increased mucosal levels of bactericidal/permeability-increasing protein
-
DOI 10.1053/gast.1996.v110.pm8608882
-
Monajemi, H.; Meenan, J.; Lamping, R.; Obradov, D. O.; Radema, S. A.; Trown, P. W.; Tytgat, G. N.; Van Deventer, S. J. Inflammatory bowel disease is associated with increased mucosal levels of bactericidal/permeability-increasing protein. Gastroenterology 1996, 110, 733-739 (Pubitemid 26071840)
-
(1996)
Gastroenterology
, vol.110
, Issue.3
, pp. 733-739
-
-
Monajemi, H.1
Meenan, J.2
Lamping, R.3
Obradov, D.O.4
Radema, S.A.5
Trown, P.W.6
Tytgat, G.N.7
Van Deventer, S.J.H.8
-
20
-
-
19744375307
-
Effect of grafted PEG on liposome size and on compressibility and packing of lipid bilayer
-
DOI 10.1016/j.chemphyslip.2005.02.003, PII S0009308405000356
-
Garbuzenko, O.; Barenholz, Y.; Priev, A. Effect of grafted PEG on liposome size and on compressibility and packing of lipid bilayer. Chem. Phys. Lipids 2005, 135, 117-129 (Pubitemid 40744733)
-
(2005)
Chemistry and Physics of Lipids
, vol.135
, Issue.2
, pp. 117-129
-
-
Garbuzenko, O.1
Barenholz, Y.2
Priev, A.3
-
21
-
-
0029117162
-
Heptan-induced chronic colitis in the rat: Alternatives to trinitrobenzene sulfonic acid
-
Wallace, J. L.; Le, T.; Carter, L.; Appleyard, C. B.; Beck, P. L. Heptan-induced chronic colitis in the rat: alternatives to trinitrobenzene sulfonic acid. J. Pharmacol. Toxicol. Methods 1995, 33, 237-239.
-
(1995)
J. Pharmacol. Toxicol. Methods
, vol.33
, pp. 237-239
-
-
Wallace, J.L.1
Le, T.2
Carter, L.3
Appleyard, C.B.4
Beck, P.L.5
-
22
-
-
0034049804
-
Relation between colonic inflammation severity and total low-molecular- Weight antioxidant profiles in experimental colitis
-
DOI 10.1023/A:1005510321278
-
Blau, S.; Kohen, R.; Bass, P.; Rubinstein, A. Relation between colonic inflammation severity and total low molecular weight antioxidant profiles in experimental colitis. Dig. Dis. Sci. 2000, 45, 1180-1187. (Pubitemid 30409464)
-
(2000)
Digestive Diseases and Sciences
, vol.45
, Issue.6
, pp. 1180-1187
-
-
Blau, S.1
Kohen, R.2
Bass, P.3
Rubinstein, A.4
-
23
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
24
-
-
0242317879
-
Enzymatic Assays for Quality Control and Pharmacokinetics of Liposome Formulations: Comparison with Nonenzymatic Conventional Methodologies
-
DOI 10.1016/S0076-6879(03)67017-5
-
Shmeeda, H.; Even-Chen, S.; Honen, R.; Cohen, R.; Weintraub, C.; Barenholz, Y. Enzymatic assays for quality control and pharmacokinetics of liposome formulations: comparison with nonenzymatic conventional methodologies. Methods Enzymol. 2003, 367, 272-292. (Pubitemid 37337839)
-
(2003)
Methods in Enzymology
, vol.367
, pp. 272-292
-
-
Shmeeda, H.1
Even-Chen, S.2
Honen, R.3
Cohen, R.4
Weintraub, C.5
Barenholz, Y.6
-
25
-
-
0031659639
-
An improved everted gut sac as a simple and accurate technique to measure paracellular transport across the small intestine
-
Bartthe, L.; Woodley, J. F.; Kenworthy, S.; Houin, G. An improved everted gut sac as a simple and accurate technique to measure paracellular transport across the small intestine. Eur. J. Drug Metab. Pharmacokinet. 1998, 23, 313-323. (Pubitemid 28401125)
-
(1998)
European Journal of Drug Metabolism and Pharmacokinetics
, vol.23
, Issue.2
, pp. 313-323
-
-
Barthe, L.1
Woodley, J.F.2
Kenworthy, S.3
Houin, G.4
-
26
-
-
0033850139
-
Mucosal 5-aminosalicylic acid concentration inversely correlates with severity of colonic inflammation in patients with ulcerative colitis
-
DOI 10.1136/gut.47.3.410
-
Frieri, G.; Giacomelli, R.; Pimpo, M.; Palumbo, G.; Passacantando, A.; Pantaleoni, G.; Caprilli, R. Mucosal 5-aminosalicylic acid concentration inversely correlates with severity of colonic inflammation in patients with ulcerative colitis. Gut 2000, 47, 410-414 (Pubitemid 30670837)
-
(2000)
Gut
, vol.47
, Issue.3
, pp. 410-414
-
-
Frieri, G.1
Giacomelli, R.2
Pimpo, M.3
Palumbo, G.4
Passacantando, A.5
Pantaleoni, G.6
Caprilli, R.7
-
27
-
-
53149084948
-
The efficacy of probiotics in IBS
-
Quigley, E. M. The efficacy of probiotics in IBS. J. Clin. Gastroenterol. 2008, 42, S85-90.
-
(2008)
J. Clin. Gastroenterol.
, vol.42
-
-
Quigley, E.M.1
-
28
-
-
18544408493
-
Development of an oral drug delivery system targeting immune-regulating cells in experimental inflammatory bowel disease: A new therapeutic strategy
-
Nakase, H.; Okazaki, K.; Tabata, Y.; Uose, S.; Ohana, M.; Uchida, K.; Matsushima, Y.; Kawanami, C.; Oshima, C.; Ikada, Y.; Chiba, T. Development of an oral drug delivery system targeting immune-regulating cells in experimental inflammatory bowel disease: a new therapeutic strategy. J. Pharmacol. Exp. Ther. 2000, 292, 15-21. (Pubitemid 30026351)
-
(2000)
Journal of Pharmacology and Experimental Therapeutics
, vol.292
, Issue.1
, pp. 15-21
-
-
Nakase, H.1
Okazaki, K.2
Tabata, Y.3
Uose, S.4
Ohana, M.5
Uchida, K.6
Matsushima, Y.7
Kawanami, C.8
Oshima, C.9
Ikada, Y.10
Chiba, T.11
-
29
-
-
0037255898
-
Biodegradable microspheres targeting mucosal immune-regulating cells: New approach for treatment of inflammatory bowel disease
-
Nakase, H.; Okazaki, K.; Tabata, Y.; Chiba, T. Biodegradable microspheres targeting mucosal immune-regulating cells: new approach for treatment of inflammatory bowel disease. J. Gastroenterol. 2003, 38, 59-62. (Pubitemid 36442889)
-
(2003)
Journal of Gastroenterology
, vol.38
, Issue.SUPPL. 15
, pp. 59-62
-
-
Nakase, H.1
Okazaki, K.2
Tabata, Y.3
Chiba, T.4
-
30
-
-
25644442467
-
Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats
-
DOI 10.1124/jpet.105.088146
-
Lamprecht, A.; Yamamoto, H.; Takeuchi, H.; Kawashima, Y. Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats. J. Pharmacol. Exp. Ther. 2005, 315, 196-202. (Pubitemid 41380512)
-
(2005)
Journal of Pharmacology and Experimental Therapeutics
, vol.315
, Issue.1
, pp. 196-202
-
-
Lamprecht, A.1
Yamamoto, H.2
Takeuchi, H.3
Kawashima, Y.4
-
31
-
-
0034756945
-
Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease
-
Lamprecht, A.; Ubrich, N.; Yamamoto, H.; Schafer, U.; Takeuchi, H.; Maincent, P.; Kawashima, Y.; Lehr, C. M. Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease. J. Pharmacol. Exp. Ther. 2001, 299, 775-781.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.299
, pp. 775-781
-
-
Lamprecht, A.1
Ubrich, N.2
Yamamoto, H.3
Schafer, U.4
Takeuchi, H.5
Maincent, P.6
Kawashima, Y.7
Lehr, C.M.8
-
32
-
-
0033995923
-
Plasma exudation, hyperaemia, and epithelial permeability in rats with oxazolone-induced colitis: Modulatory effects of budesonide
-
Ekstrom, G. M.; Andersson, S. E. Plasma exudation, hyperaemia, and epithelial permeability in rats with oxazolone-induced colitis: modulatory effects of budesonide. Scand. J. Gastroenterol. 2000, 35, 190-197
-
(2000)
Scand. J. Gastroenterol.
, vol.35
, pp. 190-197
-
-
Ekstrom, G.M.1
Andersson, S.E.2
-
33
-
-
34249933089
-
Altered permeability in inflammatory bowel disease: Pathophysiology and clinical implications
-
DOI 10.1097/MOG.0b013e32816aa392, PII 0000157420070700000005
-
Mankertz, J.; Schulzke, J. D. Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications. Curr. Opin. Gastroenterol. 2007, 23, 379-383 (Pubitemid 46878948)
-
(2007)
Current Opinion in Gastroenterology
, vol.23
, Issue.4
, pp. 379-383
-
-
Mankertz, J.1
Schulzke, J.-D.2
-
34
-
-
34648828230
-
Molecular mechanisms involved in intestinal iron absorption
-
Sharp, P.; Srai, S. K. Molecular mechanisms involved in intestinal iron absorption. World J. Gastroenterol. 2007, 13, 4716-4724 (Pubitemid 47455562)
-
(2007)
World Journal of Gastroenterology
, vol.13
, Issue.35
, pp. 4716-4724
-
-
Sharp, P.1
Srai, S.K.2
-
35
-
-
34047130786
-
Evidence for a sequential transfer of iron amongst ferritin, transferrin and transferrin receptor during duodenal absorption of iron in rat and human
-
Kolachala, V. L.; Sesikeran, B.; Nair, K. M. Evidence for a sequential transfer of iron amongst ferritin, transferrin and transferrin receptor during duodenal absorption of iron in rat and human. World J. Gastroenterol. 2007, 13, 1042-1052
-
(2007)
World J. Gastroenterol.
, vol.13
, pp. 1042-1052
-
-
Kolachala, V.L.1
Sesikeran, B.2
Nair, K.M.3
-
36
-
-
0027233827
-
The role of protein charge in protein-lipid interactions. pH-dependent changes of the electrophoretic mobility of liposomes through adsorption of watersoluble, globular proteins
-
Bergers, J. J.; Vingerhoeds, M. H.; van Bloois, L.; Herron, J. N.; Janssen, L. H.; Fischer, M. J.; Crommelin, D. J. The role of protein charge in protein-lipid interactions. pH-dependent changes of the electrophoretic mobility of liposomes through adsorption of watersoluble, globular proteins. Biochemistry 1993, 32, 4641-4649
-
(1993)
Biochemistry
, vol.32
, pp. 4641-4649
-
-
Bergers, J.J.1
Vingerhoeds, M.H.2
Van Bloois, L.3
Herron, J.N.4
Janssen, L.H.5
Fischer, M.J.6
Crommelin, D.J.7
-
37
-
-
0023441536
-
Transport of iron and transferrin synthesis by the seminiferous epithelium of the rat in vivo
-
Morales, C.; Sylvester, S. R.; Griswold, M. D. Transport of iron and transferrin synthesis by the seminiferous epithelium of the rat in vivo. Biol. Reprod. 1987, 37, 995-1005.
-
(1987)
Biol. Reprod.
, vol.37
, pp. 995-1005
-
-
Morales, C.1
Sylvester, S.R.2
Griswold, M.D.3
-
38
-
-
69249122534
-
In vitro and in vivo analysis of pulsatile biodegradation of mucoadhesive hydrogels
-
in press
-
Nadler-Milbauer, M.; Azab, A. K.; Kleinstern, J.; Barenholz, Y.; Rubinstein, A. In vitro and in vivo analysis of pulsatile biodegradation of mucoadhesive hydrogels. J. Drug Delivery Sci. Technol., in press.
-
J. Drug Delivery Sci. Technol.
-
-
Nadler-Milbauer, M.1
Azab, A.K.2
Kleinstern, J.3
Barenholz, Y.4
Rubinstein, A.5
|