Discriminating foot-and-mouth disease virus-infected and vaccinated animals by use of β-galactosidase allosteric biosensors

Clinical and Vaccine Immunology

Volumn 16, Issue 8, 2009, Pages 1228-1235

  Sánchez Aparicio, M Teresa ^a   Rosas, María Flora ^a   Ferraz, Rosa Maria ^b,c   Delgui, Laura ^a,f   Veloso, Juan J ^d   Blanco, Esther ^e   Villaverde, Antonio ^b,c   Sobrino, Francisco ^a,e  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^d Tecn Para Diagnostico e Invest SA   (Spain)

^e Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria   (Spain)

^f CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 3B; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BIOSENSOR; CATTLE; CONTROLLED STUDY; ENZYME ACTIVITY; FOOT AND MOUTH DISEASE; NONHUMAN; PRIORITY JOURNAL; SHEEP; SWINE;

ANIMALS; ANTIBODIES, VIRAL; BETA-GALACTOSIDASE; BIOSENSING TECHNIQUES; CATTLE; CATTLE DISEASES; DIAGNOSIS, DIFFERENTIAL; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; MICE; RABBITS; SHEEP; SHEEP DISEASES; SWINE; SWINE DISEASES; VIRAL VACCINES;

EID: 68149170658     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00139-09     Document Type: Article

References (54)

1. Anonymous. 2003. Council Directive 2003/85/EC on Community measures for the control of foot-and-mouth disease repealing Directive 85/511/EEC and Decisions 89/531/EEC and 91/665/EEC and amending Directive 92/46/ EEC. J. Eur. Union L306:1-87.
2. Belsham, G. J., and E. Martinez-Salas. 2004. Genome organization, translation and replication of foot-and-mouth disease virus, p. 19-52. In F. Sobrino and E. Domingo (ed.), Foot-and-mouth disease. Current perspectives. Horizon Bioscience, Norfolk, United Kingdom.
3. Benito, A., J. X. Feliu, and A. Villaverde. 1996. Beta-galactosidase enzymatic activity as a molecular probe to detect specific antibodies. J. Biol. Chem. 271:21251-21256.
4. Benito, A., and M. H. Van Regenmortel. 1998. Biosensor characterization of antigenic site A of foot-and-mouth disease virus presented in different vector systems. FEMS Immunol. Med. Microbiol. 21:101-115.
5. Benito, A., M. Vidal, and A. Villaverde. 1993. Enhanced production of pL-controlled recombinant proteins and plasmid stability in Escherichia coli RecA+ strains. J. Biotechnol. 29:299-306. (Pubitemid 23178110)
6. Benito, A., and A. Villaverde. 1994. Insertion of a 27 amino acid viral peptide in different zones of Escherichia coli beta-galactosidase: effects on the enzyme activity. FEMS Microbiol. Lett. 123:107-112.
7. Blanco, E., L. J. Romero, M. El Harrach, and J. M. Sanchez-Vizcaino. 2002. Serological evidence of FMD subclinical infection in sheep population during the 1999 epidemic in Morocco. Vet. Microbiol. 85:13-21.
8. Brocchi, E. 2003. Proc. 6th Int. Congr. Eur. Soc. Vet. Virol., abstr. 118. St. Malo, France, 24 to 27 August 2003.
9. Brocchi, E., I. E. Bergmann, A. Dekker, D. J. Paton, D. J. Sammin, M. Greiner, S. Grazioli, F. De Simone, H. Yadin, B. Haas, N. Bulut, V. Malirat, E. Neitzert, N. Goris, S. Parida, K. Sorensen, and K. De Clercq. 2006. Comparative evaluation of six ELISAs for the detection of antibodies to the non-structural proteins of foot-and-mouth disease virus. Vaccine 24:6966-6979. (Pubitemid 46131395)
10. Clavijo, A., K. Hole, M. Li, and B. Collignon. 2006. Simultaneous detection of antibodies to foot-and-mouth disease non-structural proteins 3ABC, 3D, 3A and 3B by a multiplexed Luminex assay to differentiate infected from vaccinated cattle. Vaccine 24:1693-1704. (Pubitemid 43238247)
11. Cornish-Bowden, A. 2004. Fundamentals of enzyme kinetics. Portland Press, London, United Kingdom.
12. Cowan, K. M., and J. H. Graves. 1966. A third antigenic component associated with foot-and-mouth disease infection. Virology 30:528-540.
13. De Diego, M., E. Brocchi, D. Mackay, and F. De Simone. 1997. The nonstructural polyprotein 3ABC of foot-and-mouth disease virus as a diagnostic antigen in ELISA to differentiate infected from vaccinated cattle. Arch. Virol. 142:2021-2033.
14. Doel, T. R. 2003. FMD vaccines. Virus Res. 91:81-99.
15. Domingo, E., M. G. Mateu, M. A. Martínez, J. Dopazo, A. Moya, and F. Sobrino (ed.). 1990. Genetic variability and antigenic diversity of foot-andmouth disease virus, vol.2. Academic Press Inc., London, United Kingdom.
16. Domingo, E., N. Verdaguer, W. F. Ochoa, C. M. Ruiz-Jarabo, N. Sevilla, E. Baranowski, M. G. Mateu, and I. Fita. 1999. Biochemical and structural studies with neutralizing antibodies raised against foot-and-mouth disease virus. Virus Res. 62:169-175. (Pubitemid 29393117)
17. Feliu, J. X., N. Ferrer-Miralles, E. Blanco, D. Cazorla, F. Sobrino, and A. Villaverde. 2002. Enhanced response to antibody binding in engineered beta-galactosidase enzymatic sensors. Biochim. Biophys. Acta 1596:212-224.
18. Feliu, J. X., E. Ramirez, and A. Villaverde. 1998. Distinct mechanisms of antibody-mediated enzymatic reactivation in beta-galactosidase molecular sensors. FEBS Lett. 438:267-271.
19. Feliu, J. X., and A. Villaverde. 1998. Engineering of solvent-exposed loops in Escherichia coli beta-galactosidase. FEBS Lett. 434:23-27. (Pubitemid 28404655)
20. Ferraz, R. M., A. Aris, M. A. Martinez, and A. Villaverde. 2006. Highthroughput, functional screening of the anti-HIV-1 humoral response by an enzymatic nanosensor. Mol. Immunol. 43:2119-2123.
21. Ferraz, R. M., A. Aris, G. González, J. López- Santín, A. Villaverde, and G. Alvaro. 2007. Allosteric molecular sensing of anti-HIV antibodies by an immobilized, engineered beta-galactosidase. Enzyme Microb. Technol. 41: 492-497.
22. Ferraz, R. M., M. A. Martinez, R. Cubarsi, and A. Villaverde. 2008. Antiretroviral therapy-induced functional modification of IgG4 and IgM responses in HIV-1-infected individuals screened by an allosteric biosensor. J. Biomol. Screen. 13:817-821.
23. Ferraz, R. M., A. Vera, A. Aris, and A. Villaverde. 2006. Insertional protein engineering for analytical molecular sensing. Microb. Cell Fact. 5:15.
24. Ferrer-Miralles, N., J. X. Feliu, S. Vandevuer, A. Muller, J. Cabrera-Crespo, I. Ortmans, F. Hoffmann, D. Cazorla, U. Rinas, M. Prevost, and A. Villaverde. 2001. Engineering regulable Escherichia coli beta-galactosidases as biosensors for anti-HIV antibody detection in human sera. J. Biol. Chem. 276:40087-40095.
25. Ferrer-Miralles, N., J. X. Feliu, and A. Villaverde. 2000. Molecular mechanisms for antibody-mediated modulation of peptide-displaying enzyme sensors. Biochem. Biophys. Res. Commun. 275:360-364.
26. Forss, S., K. Strebel, E. Beck, and H. Schaller. 1984. Nucleotide sequence and genome organization of foot-and-mouth disease virus. Nucleic Acids Res. 12:6587-6601.
27. García-Briones, M., M. F. Rosas, M. Gonzalez-Magaldi, M. A. Martin- Acebes, F. Sobrino, and R. Armas-Portela. 2006. Differential distribution of non-structural proteins of foot-and-mouth disease virus in BHK-21 cells. Virology 349:409-421. (Pubitemid 44208678)
28. Hamblin, C., I. T. Barnett, and R. S. Hedger. 1986. A new enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies against footand- mouth disease virus. I. Development and method of ELISA. J. Immunol. Methods 93:115-121.
29. Kalnins, A., K. Otto, U. Ruther, and B. Muller-Hill. 1983. Sequence of the lacZ gene of Escherichia coli. EMBO J. 2:593-597.
30. Kitching, R. P. 2004. Diagnosis and control of foot-and-mouth disease. In F. Sobrino and E. Domingo (ed.), Foot-and-mouth disease. Current perspectives. Horizon Bioscience, Norfolk, United Kingdom.
31. Lubroth, J., and F. Brown. 1995. Identification of native foot-and-mouth disease virus non-structural protein 2C as a serological indicator to differentiate infected from vaccinated livestock. Res. Vet. Sci. 59:70-78.
32. Mackay, D. K. 1998. Differentiating infection from vaccination in foot-andmouth disease. Vet. Q. 20(Suppl. 2):S2-S5.
33. Martínez-Salas, E. M., M. Sáiz, and F. Sobrino. 2008. Foot-and-mouth disease virus. In T. C. Mettenleiter and F. Sobrino (ed.), Animal viruses. Molecular biology. Caister Academic Press, Norfolk, United Kingdom.
34. Mason, P. W., M. J. Grubman, and B. Baxt. 2003. Molecular basis of pathogenesis of FMDV. Virus Res. 91:9-32.
35. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
36. Neitzert, E., E. Beck, P. A. de Mello, I. Gomes, and I. E. Bergmann. 1991. Expression of the aphthovirus RNA polymerase gene in Escherichia coli and its use together with other bioengineered nonstructural antigens in detection of late persistent infections. Virology 184:799-804.
37. Núñez, J. I., E. Baranowski, N. Molina, C. M. Ruiz-Jarabo, C. Sanchez, E. Domingo, and F. Sobrino. 2001. A single amino acid substitution in nonstructural protein 3A can mediate adaptation of foot-and-mouth disease virus to the guinea pig. J. Virol. 75:3977-3983.
38. Pereira, H. G. 1981. Foot-and-mouth disease. Academic Press Inc., London, United Kingdom.
39. Pinto, A. A., and A. J. Garland. 1979. Immune response to virus-infectionassociated (VIA) antigen in cattle repeatedly vaccinated with foot-andmouth disease virus inactivated by formalin or acetylethyleneimine. J. Hyg. (London) 82:41-50.
40. Rodríguez, A., J. Dopazo, J. C. Saiz, and F. Sobrino. 1994. Immunogenicity of non-structural proteins of foot-and-mouth disease virus: differences between infected and vaccinated swine. Arch. Virol. 136:123-131.
41. Salt, J. S. 1993. The carrier state in foot and mouth disease-an immunological review. Br. Vet. J. 149:207-223.
42. Samuel, A. R., and N. J. Knowles. 2001. Foot-and-mouth disease virus: cause of the recent crisis for the UK livestock industry. Trends Genet. 17:421-424.
43. Schauder, B., H. Blocker, R. Frank, and J. E. McCarthy. 1987. Inducible expression vectors incorporating the Escherichia coli atpE translational initiation region. Gene 52:279-283. (Pubitemid 17090755)
44. Shen, F., P. D. Chen, A. M. Walfield, J. Ye, J. House, F. Brown, and C. Y. Wang. 1999. Differentiation of convalescent animals from those vaccinated against foot-and-mouth disease by a peptide ELISA. Vaccine 17:3039-3049. (Pubitemid 29366984)
45. Sobrino, F., and E. Domingo (ed.). 2004. Foot-and-mouth disease. Current perspectives. Horizon Bioscience, Norfolk, United Kingdom.
46. Sobrino, F., M. Davila, J. Ortin, and E. Domingo. 1983. Multiple genetic variants arise in the course of replication of foot-and-mouth disease virus in cell culture. Virology 128:310-318.
47. Sobrino, F., M. Saiz, M. A. Jimenez-Clavero, J. I. Nunez, M. F. Rosas, E. Baranowski, and V. Ley. 2001. Foot-and-mouth disease virus: a long known virus, but a current threat. Vet. Res. 32:1-30.
48. Sørensen, K. J., K. de Stricker, K. C. Dyrting, S. Grazioli, and B. Haas. 2005. Differentiation of foot-and-mouth disease virus infected animals from vaccinated animals using a blocking ELISA based on baculovirus expressed FMDV 3ABC antigen and a 3ABC monoclonal antibody. Arch. Virol. 150: 805-814.
49. Studier, F. W., and B. A. Moffatt. 1986. Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol. 189:113-130.
50. Sutmoller, P., S. S. Barteling, R. C. Olascoaga, and K. J. Sumption. 2003. Control and eradication of foot-and-mouth disease. Virus Res. 91:101-144.
51. Thomson, G. R., W. Vosloo, and A. D. Bastos. 2003. Foot and mouth disease in wildlife. Virus Res. 91:145-161.
52. Toja, M., C. Escarmis, and E. Domingo. 1999. Genomic nucleotide sequence of a foot-and-mouth disease virus clone and its persistent derivatives. Implications for the evolution of viral quasispecies during a persistent infection. Virus Res. 64:161-171.
53. Villaverde, A. 2003. Allosteric enzymes as biosensors for molecular diagnosis. FEBS Lett. 554:169-172. (Pubitemid 37324834)
54. Villinger, F., H. K. Mueller, L. Bruckner, M. Ackermann, and U. Kihm. 1989. Antibodies to foot-and-mouth disease virus infection associated (VIA) antigen: use of a bioengineered VIA protein as antigen in an ELISA. Vet. Microbiol. 20:235-246.