Investigation and prediction of the severity of p53 mutants using parameters from structural calculations

FEBS Journal

Volumn 276, Issue 15, 2009, Pages 4142-4155

  Carlsson, Jonas ^a   Soussi, Thierry ^b,c   Persson, Bengt ^a,b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c SORBONNE UNIVERSITÉ   (France)

Author keywords

Cancer; Molecular modelling; Mutations; P53; Structural prediction

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; MUTANT PROTEIN; PROTEIN AIP; PROTEIN BAX; PROTEIN GAD45; PROTEIN MDM2; PROTEIN NOXA; PROTEIN P53; STRATIFIN; UNCLASSIFIED DRUG;

ALGORITHM; ARTICLE; AUTOMATION; DISABILITY SEVERITY; ENERGY YIELD; HEAT TOLERANCE; HUMAN; HYDROPHOBICITY; MOLECULAR MECHANICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN STABILITY; RNA TRANSLATION; SEQUENCE ANALYSIS; STRUCTURAL PROTEOMICS; TUMOR SUPPRESSOR GENE;

ALGORITHMS; BREAST NEOPLASMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FEMALE; HUMANS; MODELS, MOLECULAR; MUTATION; NEOPLASMS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN CONFORMATION; SEVERITY OF ILLNESS INDEX; TUMOR SUPPRESSOR PROTEIN P53;

EID: 68149169706     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07124.x     Document Type: Article

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