Experimental study of the effects of marrow mesenchymal stem cells transfected with hypoxia-inducible factor-1 Gene

Journal of Biomedicine and Biotechnology

Volumn 2009, Issue , 2009, Pages

  Tang, Tao ^a   Yang, Jinfu ^a   Li, Feng ^a   Zhou, Wenwu ^b   Liu, Jian ^b   Tan, Zhiping ^a   Zheng, Wei ^c   Yang, Yifeng ^a   Zhou, Xinmin ^a   Hu, Jianguo ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b HUNAN CHILDREN'S HOSPITAL   (China)

^c HUNAN PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; CALCIUM; LEUKOCYTE ANTIGEN;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CD34 SELECTION; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC TRANSFECTION; HEART MUSCLE CELL; IN VITRO STUDY; MESENCHYMAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; POLYMERASE CHAIN REACTION; RAT; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BONE MARROW CELL; CELL HYPOXIA; CELL SHAPE; CYTOLOGY; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; PHYSIOLOGY; PLASMID; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WISTAR RAT;

EUKARYOTA; RATTUS NORVEGICUS;

ANIMALS; ANTIGENS, CD; BLOTTING, WESTERN; BONE MARROW CELLS; CALCIUM; CELL DIFFERENTIATION; CELL HYPOXIA; CELL SHAPE; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MESENCHYMAL STEM CELLS; PLASMIDS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFECTION;

EID: 68149149068     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2009/128627     Document Type: Article

References (22)

1. Haizheng Z., Jihong G., Epidemiology and primary prevention of coronary artery disease Chinese Journal of Practical Internal Medicine 2002 22 8 449 451
2. Kastrup J., Jrgensen E., Rck A., Direct intramyocardial plasmid vascular endothelial growth factor- A 165 gene therapy in patients with stable severe angina pectoris: a randomized double-blind placebo-controlled study: the Euroinject One trial Journal of the American College of Cardiology 2005 45 7 982 988
3. Ripa R. S., Wang Y., Jrgensen E., Johnsen H. E., Hesse B., Kastrup J., Intramyocardial injection of vascular endothelial growth factor- A 165 plasmid followed by granulocyte-colony stimulating factor to induce angiogenesis in patients with severe chronic ischaemic heart disease European Heart Journal 2006 27 15 1785 1792
4. Kido M., Du L., Sullivan C. C., Hypoxia-inducible factor 1- reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse Journal of the American College of Cardiology 2005 46 11 2116 2124
5. Lee S. H., Wolf P. L., Escudero R., Deutsch R., Jamieson S. W., Thistlethwaite P. A., Early expression of angiogenesis factors in acute myocardial ischemia and infarction The New England Journal of Medicine 2000 342 9 626 633
6. Orlic D., Kajstura J., Chimenti S., Bone marrow cells regenerate infarcted myocardium Nature 2001 410 6829 701 705
7. Takano H., Ohtsuka M., Akazawa H., Pleiotropic effects of cytokines on acute myocardial infarction: G-CSF as a novel therapy for acute myocardial infarction Current Pharmaceutical Design 2003 9 14 1121 1127
8. Orlic D., Kajstura J., Chimenti S., Mobilized bone marrow cells repair the infarcted heart, improving function and survival Proceedings of the National Academy of Sciences of the United States of America 2001 98 18 10344 10349
9. Arbeit J. M., Quiescent hypervascularity mediated by gain of HIF-1 function Cold Spring Harbor Symposia on Quantitative Biology 2002 67 133 142
10. Sambrook J., Fritsch E. F., Maniatis T., Molecular Cloning: A Laboratory Manual 1989 New York, NY, USA Cold Spring Harbor Laboratory
11. Wen-Wu Z., Jian-Guo H., Yan-Ling M., Experimental study of the transfection of human VEGF165 gene into rat bone mes enchymal stem cells in vitro Life Science Research 2005 9 4 301 307
12. Lehrman S., Virus treatment questioned after gene therapy death Nature 1999 401 6753 517 518
13. Marshall E., Clinical research: gene therapy a suspect in leukemia-like disease Science 2002 298 5591 34 35
14. Eastman S. J., Tousignant J. D., Lukason M. J., Optimization of formulations and conditions for the aerosol delivery of functional cationic lipid: DNA complexes Human Gene Therapy 1997 8 3 313 322
15. Felgner P. L., Improvements in cationic liposomes for in vivo gene transfer Human Gene Therapy 1996 7 15 1791 1793
16. Zanta M. A., Belguise-Valladier P., Behr J.-P., Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus Proceedings of the National Academy of Sciences of the United States of America 1999 96 1 91 96
17. Zhang P., Zhang H., Hu S. S., Chen L. G., Wei Y. J., Plasmid transfection of rat bone marrow mesenchymal stem cells by cationic lipid for gene-modified cell transplantation therapy Acta Academiae Medicinae Sinicae 2005 27 4 504 508
18. Forsythe J. A., Jiang B. H., Iyer N. V., Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 Molecular and Cellular Biology 1996 16 9 4606 4613
19. Waltenberger J., Mayr U., Pentz S., Hombach V., Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia Circulation 1996 94 7 1647 1654
20. Mller-Ehmsen J., Whittaker P., Kloner R. A., Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium Journal of Molecular and Cellular Cardiology 2002 34 2 107 116
21. Tang Y. L., Tang Y., Zhang Y. C., Qian K., Shen L., Phillips M. I., Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vector Journal of the American College of Cardiology 2005 46 7 1339 1350
22. Carmo V. A. S., De Oliveira M. C., Reis E. C. O., Physicochemical characterization and study of in vitro interactions of pH-sensitive liposomes with the complement system Journal of Liposome Research 2008 18 1 59 70