Early childhood obesity is associated with compromised cerebellar development

Developmental Neuropsychology

Volumn 34, Issue 3, 2009, Pages 272-283

  Miller, Jennifer L ^a,b   Couch, Jessica ^a   Schwenk, Krista ^b   Long, Michelle ^b   Towler, Stephen ^b   Theriaque, Douglas W ^b   He, Guojun ^a   Liu, Yijun ^a   Driscoll, Daniel J ^a   Leonard, Christiana M ^b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; BRAIN SIZE; CEREBELLUM CORTEX; CHILD; CHILD DEVELOPMENT; CHILDHOOD DISEASE; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; COGNITIVE DEVELOPMENT; CONTROLLED STUDY; FEMALE; GENOME IMPRINTING; HUMAN; INTELLIGENCE; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; PRADER WILLI SYNDROME; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SIBLING; ADOLESCENT; ANALYSIS OF VARIANCE; CEREBELLUM; CROSS-SECTIONAL STUDY; GROWTH, DEVELOPMENT AND AGING; METHODOLOGY; NEUROPSYCHOLOGICAL TEST; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADOLESCENT; ANALYSIS OF VARIANCE; CEREBELLUM; CEREBRAL CORTEX; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INTELLIGENCE; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; OBESITY; PRADER-WILLI SYNDROME; YOUNG ADULT;

EID: 68149096833     PISSN: 87565641     EISSN: None     Source Type: Journal    
DOI: 10.1080/87565640802530961     Document Type: Article

References (25)

1. Belichenko, N. P., Belichenko, P. V., Li, H. H., Mobley, W. C., & Francke, U. (2008). Comparative study of brain morphology in Mecp2 mutant mouse models of Rett syndrome. Journal of Comparative Neurology, 508(1),184-195.
2. Bittel, D. C., & Butler, M.G. (2005). Prader-Willi syndrome: Clinical genetics, cytogenetics and molecular biology. Expert Reviews in Molecular Medicine, 7(14),1-20.
3. Crnic, K. A., Sulzbacher, S., Snow, J., & Holm, V. A. (1980). Preventing mental retardation associated with gross obesity in the Prader-Willi syndrome. Pediatrics, 6(5),787-789.
4. Elenkov, I. J. (2008). Neurohormonal-cytokine interactions: Implications for inflammation, common human diseases, and well-being. Neurochemistry International, 2(1-2):40-51.
5. Floeter, M. K., & Greenough, W. T. (1979). Cerebellar plasticity: Modification of Purkinje cells by differential rearing in monkeys. Science, 6(12), 227-229.
6. Glenn, C. G., Driscoll, D. J., Thomas, P. Y.,&Nicholls, R. D. (1997). Genomic imprinting: Potential function and mechanisms revealed by the Prader-Willi and Angelman syndromes. Molecular Human Reproduction, 3, 321-332.
7. Goldstone, A. P. (2004). Prader-Willi syndrome: Advances in genetics, pathophysiology and treatment. Trends in Endocrinology and Metabolism, 5(1),12-20.
8. Hayashi, M., Itoh, M., Kabasawa, Y., Hayashi, H., Satoh, J.,&Morimatsu, Y. (1992). A neuropathological study of a case of the Prader-Willi syndrome with an interstitial deletion of the proximal long arm of chromosome 15. Brain and Development, 4(1), 58-62.
9. Huber, K. M. (2006). The fragile X-cerebellum connection. Trends in Neurosciences, 9(4), 183-185.
10. Jernigan, T. L., Bellugi, U., Sowell, E., Doherty, S., & Hesselink, J. R. (1993). Cerebral morphologic distinctions between Williams and Down syndromes. Archives of Neurology, 50(2), 186-191.
11. Lee, S., Walker, C. L., & Wevrick, R. (2003). Prader-Willi syndrome transcripts are expressed in phenotypically significant regions of the developing mouse brain. Gene Expression Patterns, 3(5), 599-609.
12. Lee, S., Walker, C. L., Karten, B., Kuny, S. L., Tennese, A. A., O'Neill, M. A.,&Wevrick, R. (2005). Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth. Human Molecular Genetics, 14(5), 627-637.
13. Miller, J. L., Couch, J. A., Schmalfuss, I., He, G., Liu, Y., & Driscoll, D. J. (2007). Intracranial abnormalities detected by three-dimensional magnetic resonance imaging in Prader-Willi syndrome. American Journal of Medical Genetics Part A, 143(5), 476-483.
14. Miller, J., Kranzler, J., Liu, Y., Schmalfuss, I., Theriaque, D. W., Shuster, J. J., Hatfield, A., Mueller, O. T., Goldstone, A. P., Sahoo, T., Beaudet, A. L., & Driscoll, D. J. (2006). Neurocognitive findings in Prader-Willi syndrome and early-onset morbid obesity. The Journal of Pediatrics, 149(2), 192-198.
15. Moldrich, R. X., Dauphinot, L., Laffaire, J., Rossier, J., & Potier, M. C. (2007). Down syndrome gene dosage imbalance on cerebellum development. Progress in Neurobiology, 82(2), 87-94.
16. Niccols, A. (2007). Fetal alcohol syndrome and the developing socio-emotional brain. Brain and Cognition, 65(1), 135-142.
17. Nicholls, R. D., & Knepper, J. L. (2001). Genome organization, function and imprinting in Prader-Willi and Angelman syndromes. Annual Review of Genomics and Human Genetics, 2, 153-175.
18. Pae, E. K., Chien, P., & Harper, R. M. (2005). Intermittent hypoxia damages cerebellar cortex and deep nuclei. Neuroscience Letters, 375(2), 123-128.
19. Rapoport, M., van Reekum, R., & Mayberg, H.(2000). The role of the cerebellum in cognition and behavior: A selective review. The Journal of Neuropsychiatry and Clinical Neurosciences, 12(2), 193-198.
20. Smith, S. M., Jenkinson, M., Johansen-Berg, H., Rueckert, D., Nichols, T. E., Mackay, C. E., Watkins, K. E., Ciccarelli, O., Zaheer Cader, M., Matthews, P., & Behrens, T. E. J. (2006). Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data. Neuroimage 31, 1487-1505.
21. Sriram, K., Benkovic, S. A., Miller, D. B., & O'Callaghan, J. P. (2002). Obesity exacerbates chemically induced neurodegeneration. Neuroscience, 115(4), 1335-1346.
22. Steinlin, M. (2007). The cerebellum in cognitive processes: Supporting studies in children. Cerebellum 6(3), 237-241.
23. Titomanlio, L., De Brasi, D., Romano, A., Genesio, R., Diano, A. A., & Del Giudice, E. (2006). Partial cerebellar hypoplasia in a patient with Prader-Willi syndrome. Acta Paediatrica, 95(7), 861-863.
24. Whitmer, R. A., Gunderson, E. P., Barrett-Connor, E., Quesenberry, C. P. Jr., & Yaffe, K. (2005). Obesity in middle age and the future risk of dementia. British Medical Journal, 330, 1360.
25. Woodcock, R. W., McGrew, K. S., & Mather, N. (2001). Woodcock-Johnson Psycho-Educational Battery III. Itasca, IL: Riverside Publishing.