Social regulation of human gene expression

Current Directions in Psychological Science

Volumn 18, Issue 3, 2009, Pages 132-137

  Cole, Steve W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gene environment interactions; Genetics; Genomics; Social factors

Indexed keywords

EID: 68049133023     PISSN: 09637214     EISSN: 14678721     Source Type: Journal    
DOI: 10.1111/j.1467-8721.2009.01623.x     Document Type: Article

References (22)

1. Cole, S.W., et al. (2007). (See References). This study provided the first indication that social factors might systematically regulate human genome activity in the immune system, and it pioneered novel strategies for identifying the social signal transduction pathways involved.
2. Caspi, A., et al. (2003). (See References). A landmark paper identifying a transcription-regulating DNA polymorphism as a molecular vulnerability factor for the development of depression in response to psychological stress.
3. Sloan, E.K., et al. (2007). (See References). A key experimental study showing that social stress can activate neural growth genes in non-human primates, and thereby remodel the neural structures that transmit social influences into gene expression in the immune system and viral pathogens.
4. Miller, G., Chen, E., & Cole, S.W. (2009). Health psychology: Developing biologically plausible models linking the social world and physical health. Annual Review of Psychology, 60, 501-524. This article provides a deeper review of recent research on psychological regulation of gene expression in human health.
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