Affinity and specificity of levamlodipine-human serum albumin interactions: Insights into its carrier function

Biophysical Journal

Volumn 96, Issue 10, 2009, Pages 3917-3925

  Liu, Zuojia ^a   Zheng, Xiliang ^a   Yang, Xiurong ^a   Wang, Erkang ^a   Wang, Jin ^a,b  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE; HUMAN SERUM ALBUMIN; LEVAMLODIPINE; UNCLASSIFIED DRUG; 2 ((2 AMINOETHOXY)METHYL) 4 (2 CHLOROPHENYL) 3 ETHOXY CARBONYL 5 METHOXYCARBONYL 6 METHYL 1,4 DIHYDROPYRIDINE; 2-((2-AMINOETHOXY)METHYL)-4-(2-CHLOROPHENYL)-3-ETHOXY-CARBONYL-5-METHOXYCARBONYL-6-METHYL-1,4-DIHYDROPYRIDINE; CARRIER PROTEIN; DRUG DERIVATIVE; NICOTINIC ACID; SERUM ALBUMIN;

ARTICLE; CHROMATOGRAPHY; DRUG ACTIVITY; DRUG BINDING; DRUG BINDING SITE; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG TARGETING; ENERGY TRANSFER; FLUORESCENCE; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR RECOGNITION; PROTEIN DNA INTERACTION; PROTEIN PROTEIN INTERACTION; THERMODYNAMICS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; ENZYME SPECIFICITY; HUMAN; METABOLISM; PROTEIN BINDING; SPECTROFLUOROMETRY; ULTRAVIOLET SPECTROPHOTOMETRY;

CARRIER PROTEINS; COMPUTER SIMULATION; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NIACIN; PROTEIN BINDING; SERUM ALBUMIN; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 68049128000     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2008.12.3965     Document Type: Article

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