Electrostatic binding of nanoparticles to mesenchymal stem cells via high molecular weight polyelectrolyte chains

Journal of Tissue Engineering and Regenerative Medicine

Volumn 3, Issue 4, 2009, Pages 243-254

  Heng, Boon C ^a   Cowan, Catherine M ^a   Davalian, Dariush ^a   Stankus, John ^a   Duong Hong, Duc ^a   Ehrenreich, Kevin ^a   Basu, Shubhayu ^b  

^a ABBOTT VASCULAR   (United States)

^b Global Cardiovascular Innovation Center   (United States)

Author keywords

Chitosan; Hyaluronan; Mesenchymal; Nanoparticle; Poly L lysine; Stem cells

Indexed keywords

BIOCOMPATIBILITY; CARDIOVASCULAR SYSTEM; CELL CULTURE; CELL DEATH; CELL MEMBRANES; CHAINS; CONTROLLED DRUG DELIVERY; HYALURONIC ACID; MOLECULAR BIOLOGY; MOLECULAR WEIGHT; MOLECULES; NANOPARTICLES; POLYELECTROLYTES; STEM CELLS; TARGETED DRUG DELIVERY;

CYTOKINES; EXTRACELLULAR MATRICES; GROWTH FACTOR; HIGH MOLECULAR WEIGHT POLYELECTROLYTES; HYALURONAN; MESENCHYMAL; MESENCHYMAL STEM CELL; POLY-L-LYSINE; POLYELECTROLYTE CHAIN; STEM-CELL;

CHITOSAN;

CHITOSAN; HERMES ANTIGEN; HYALURONIC ACID; NANOPARTICLE; POLYELECTROLYTE; POLYLYSINE; ELECTROLYTE;

ARTICLE; BIOCOMPATIBILITY; CELL ADHESION; CELL INTERACTION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONJUGATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MOLECULAR WEIGHT; MONOLAYER CULTURE; PRIORITY JOURNAL; CELL CULTURE; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOLOGY; METABOLISM; STATIC ELECTRICITY;

CELL ADHESION; CELLS, CULTURED; CHITOSAN; ELECTROLYTES; HUMANS; HYALURONIC ACID; MESENCHYMAL STEM CELLS; MICROSCOPY, CONFOCAL; MOLECULAR WEIGHT; NANOPARTICLES; STATIC ELECTRICITY;

EID: 68049127993     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.160     Document Type: Article

References (38)

1. Aiba S. 1989; Studies on chitosan: 2. Solution stability and reactivity of partially N-acetylated chitosan derivatives in aqueous media. Int J Biol Macromol 11(4): 249-252.
2. Bajada S, Mazakova I, Richardson JB, et al. 2008; Updates on stem cells and their applications in regenerative medicine. J Tissue Eng Regen Med 2(4): 169-183.
3. Brohede U, Atluri R, Garcia-Bennett AE, et al. 2008; Sustained release from mesoporous nanoparticles: evaluation of structural properties associated with release rate. Curr Drug Deliv 5(3): 177-185.
4. Chiellini F, Piras AM, Errico C, et al. 2008; Micro/nanostructured polymeric systems for biomedical and pharmaceutical applications. Nanomedicine 3(3): 367-393.
5. Ciofani G, Raffa V, Menciassi A, et al. 2008; Alginate and chitosan particles as drug delivery system for cell therapy. Biomed Microdevices 10(2): 131-140.
6. de Jong WH, Borm PJ. 2008; Drug delivery and nanoparticles: applications and hazards. Int J Nanomed 3(2): 133-149.
7. Di Martino A, Sittinger M, Risbud MV. 2005; Chitosan: a versatile biopolymer for orthopaedic tissue-engineering. Biomaterials 26(30): 5983-5990.
8. Goldberg M, Langer R, Jia X. 2007; Nanostructured materials for applications in drug delivery and tissue engineering. J Biomater Sci Polym Ed 18(3): 241-268.
9. Kadl A, Bochkov VN, Huber J, et al. 2004; Apoptotic cells as sources for biologically active oxidized phospholipids. Antioxid Redox Signal 6(2): 311-320.
10. Kalantar-Zadeh K, Anker SD, Horwich TB, et al. 2008; Nutritional and anti-inflammatory interventions in chronic heart failure. Am J Cardiol 101(11A): 89-103E.
11. Kogan G, Solt́es L, Stern R, et al. 2007; Hyaluronic acid: a natural biopolymer with a broad range of biomedical and industrial applications. Biotechnol Lett 29(1): 17-25.
12. Lee M, Vasioukhin V. 2008; Cell polarity and cancer - cell and tissue polarity as a non-canonical tumor suppressor. J Cell Sci 121(8): 1141-1150.
13. Lesley J, Hyman R, Kincade PW. 1993; CD44 and its interaction with extracellular matrix. Adv Immunol 54: 271-335.
14. Li GR, Sun H, Deng X, et al. 2005; Characterization of ionic currents in human mesenchymal stem cells from bone marrow. Stem Cells 23(3): 371-382.
15. Lin H. 2008; Cell biology of stem cells: an enigma of asymmetry and self-renewal. J Cell Biol 180(2): 257-260.
16. Liu D, Liu T, Li R, et al. 1998a; Mechanisms regulating the binding activity of CD44 to hyaluronic acid. Front Biosci 3: d631-636.
17. Liu D, Liu T, Sy MS. 1998b; Identification of two regions in the cytoplasmic domain of CD44 through which PMA, calcium, and foskolin differentially regulate the binding of CD44 to hyaluronic acid. Cell Immunol 190(2): 132-140.
18. Liu Y, Miyoshi H, Nakamura M. 2007; Nanomedicine for drug delivery and imaging: a promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles. Int J Cancer 120(12): 2527-2537.
19. Marcato PD, Duŕan N. 2008; New aspects of nanopharmaceutical delivery systems. J Nanosci Nanotechnol 8(5): 2216-2229.
20. Marhaba R, Zöller M. 2004; CD44 in cancer progression: adhesion, migration and growth regulation. J Mol Histol 35(3): 211-231.
21. Mooney DJ, Vandenburgh H. 2008; Cell delivery mechanisms for tissue repair. Cell Stem Cell 2(3): 205-213.
22. Moreau E, Domurado M, Chapon P, et al. 2002; Biocompatibility of polycations: in vitro agglutination and lysis of red blood cells and in vivo toxicity. J Drug Target 10(2): 161-173.
23. Mosmann T. 1983; Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65(1-2): 55-63.
24. Nakase T, Yamazaki T, Ogura N, et al. 2008; The impact of inflammation on the pathogenesis and prognosis of ischemic stroke. J Neurol Sci 271(1-2): 104-109.
25. Naor D, Wallach-Dayan SB, Zahalka MA, et al. 2008; Involvement of CD44, a molecule with a thousand faces, in cancer dissemination. Semin Cancer Biol 18(4): 260-267.
26. Orive G, Tam SK, Pedraz JL, et al. 2006; Biocompatibility of alginatepoly-L-lysine microcapsules for cell therapy. Biomaterials 27(20): 3691-3700.
27. Park JS, Park K, Woo DG, et al. 2008; PLGA microsphere construct coated with TGF-β3 loaded nanoparticles for neocartilage formation. Biomacromolecules 9(8): 2162-2169.
28. Payne AG. 2004; Using immunomagnetic technology and other means to facilitate stem cell homing. Med Hypotheses 62(5): 718-720.
29. Ponta H, Sherman L, Herrlich PA. 2003; CD44: from adhesion molecules to signalling regulators. Nat Rev Mol Cell Biol 4(1): 33-45.
30. Slemmer JE, Shacka JJ, Sweeney MI, et al. 2008; Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging. Curr Med Chem 15(4): 404-414.
31. Tae SK, Lee SH, Park JS, et al. 2006; Mesenchymal stem cells for tissue engineering and regenerative medicine. Biomed Mater 1(2): 63-71.
32. Tharanathan RN, Kittur FS. 2003; Chitin - the undisputed biomolecule of great potential. Crit Rev Food Sci Nutr 43(1): 61-87.
33. Vanlangenakker N, Berghe TV, Krysko DV, et al. 2008; Molecular mechanisms and pathophysiology of necrotic cell death. Curr Mol Med 8(3): 207-220.
34. Vats A, Tolley NS, Bishop AE, et al. 2005; Embryonic stem cells and tissue engineering: delivering stem cells to the clinic. J R Soc Med 98(8): 346-350.
35. Vereb G, Szöllosi J, Matkó J, et al. 2003; Dynamic, yet structured: the cell membrane three decades after the Singer-Nicolson model. Proc Natl Acad Sci USA 100(14): 8053-8058.
36. Wodarz A, Näthke I. 2007; Cell polarity in development and cancer. Nat Cell Biol 9(9): 1016-1024.
37. Yao EH, Yu Y, Fukuda N. 2006; Oxidative stress on progenitor and stem cells in cardiovascular diseases. Curr Pharm Biotechnol 7(2): 101-108.
38. Zhang XG, Teng DY, Wu ZM, et al. 2008; PEG-grafted chitosan nanoparticles as an injectable carrier for sustained protein release. J Mater Sci Mater Med 19(12): 3525-3533.