Cell biology of stem cells: An enigma of asymmetry and self-renewal

Journal of Cell Biology

Volumn 180, Issue 2, 2008, Pages 257-260

  Lin, Haifan ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

ANIMAL CELL; CELL CYCLE; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL DIVISION; CELL MATURATION; CELL MEMBRANE; CELL POLARITY; CELL POPULATION; CELL REGENERATION; CELL RENEWAL; CELL TYPE; CELLULAR DISTRIBUTION; CENTROSOME; CONTROLLED STUDY; CYTOLOGY; DROSOPHILA MELANOGASTER; EMBRYONIC STEM CELL; MITOSIS; NEUROBLAST; NEUROEPITHELIUM; NONHUMAN; NOTE; PRIORITY JOURNAL; SPINDLE CELL; STEM CELL;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; HUMANS; STEM CELLS;

DROSOPHILA MELANOGASTER; HARNESS; MAMMALIA;

EID: 38749108081     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200712159     Document Type: Note

References (16)

1. Cai, Y., F. Yu, S. Lin, W. Chia, and X. Yang. 2003. Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions. Cell. 112:51-62.
2. Chen, D., and D. McKearin. 2005. Gene circuitry controlling a stem cell niche. Curr. Biol. 15:179-184.
3. Chia, W., W.G. Somers, and H. Wang. 2008. Drosophila neuroblast asymmetric divisions: cell cycle regulators, asymmetric protein localization, and tumorigenesis. J. Cell Biol. 180:267-272.
4. Deng, W., and H. Lin. 1997. Spectrosomes and fusomes are essential for anchoring mitotic spindles during asymmetric germ cell divisions and for the microtubule-based RNA transport during oocyte specification in Drosophila. Dev. Biol. 189:79-94.
5. Fuchs, E. 2008. Skin stem cells: rising to the surface. J. Cell Biol. 180:273-284.
6. King, F.J., A. Szakmary, D.N. Cox, and H. Lin. 2001. Yb modulates the divisions of both germline and somatic stem cells through piwi - and hh-mediated mechanisms in the Drosophila ovary. Mol. Cell. 7:497-508.
7. Kosodo, Y., K. Roper, W. Haubensak, A.M. Marzesco, D. Corbeil, and W.B. Huttner. 2004. Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells. EMBO J. 23:2314-2324.
8. Lechler, T., and E. Fuchs. 2005. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature. 437:275-280.
9. Lee, C.Y., K.J. Robinson, and C.Q. Doe. 2006. Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation. Nature. 439:594-598.
10. Lin, H. 2002. The stem-cell niche theory: lessons from flies. Nat. Rev. Genet. 3:931-940.
11. Lin, H. 2003. To be and not to be. Nature. 425:353-355.
12. McGrail, M., and T.S. Hays. 1997. The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila. Development. 124:2409-2419.
13. Song, X., C.H. Zhu, C. Doan, and T. Xie. 2 002. G ermline stem cells anchored by adherens junctions in the Drosophila ovary niches. Science. 296:1855-1857.
14. Szakmary, A., D.N. Cox, Z. Wang, and H. Lin. 2005. Regulatory relationship among piwi, pumilio, and bag-of-marbles in Drosophila germline stem cell self-renewal and differentiation. Curr. Biol. 15:171-178.
15. Wu, M., H.Y. Kwon, F. Rattis, J. Blum, C. Zhao, R. Ashkenazi, T.L. Jackson, N. Gaiano, T. Oliver, and T. Reya. 2007. Imaging hematopoietic precursor division in real time. Cell Stem Cell. 1:541-554.
16. Yamashita, Y.M., and M.T. Fuller. 2008. Asymmetric centrosome behavior and the mechanisms of stem cell division. J. Cell Biol. 180:261-266.