The vasorelaxant effect of caffeic acid phenethyl ester on porcine coronary artery ring segments

Vascular Pharmacology

Volumn 51, Issue 2-3, 2009, Pages 78-83

  Long, Yuan ^a   Han, Min ^a   Chen, Juan ^a   Tian, Xiao Zhu ^a   Chen, Qiang ^a   Wang, Rui ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

adrenoceptor; CAPE; Coronary artery; Endothelium; NO

Indexed keywords

9 (TETRAHYDRO 2 FURYL)ADENINE; BETA ADRENERGIC RECEPTOR; CAFFEIC ACID PHENETHYL ESTER; CALCIUM CHLORIDE; CYCLIC AMP; CYCLIC GMP; INDOMETACIN; METHYLENE BLUE; N(G) NITROARGININE; NITRIC OXIDE; POTASSIUM CHLORIDE; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENDOTHELIUM; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SECOND MESSENGER; SWINE; VASCULAR RING; VASODILATATION;

ADENYLATE CYCLASE; ADRENERGIC BETA-ANTAGONISTS; ANALYSIS OF VARIANCE; ANIMALS; CAFFEIC ACIDS; CALCIUM SIGNALING; CORONARY ARTERY DISEASE; CORONARY VESSELS; CYCLIC GMP; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE SYNTHASE; PHENYLETHYL ALCOHOL; SWINE; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 68049126237     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2009.03.002     Document Type: Article

References (59)

1. Agnisola C. Role of nitric oxide in the control of coronary resistance in teleosts. Comp. Biochem. Physiol. A. Mol. Integr. Physiol. 142 (2005) 178-187
2. Akpinar M.B., Erdogan H., Sahin S., Ucar F., and Ilhan A. Protective effects of caffeic acid phenethyl ester on rotenone-induced myocardial oxidative injury. Pestic. Biochem. Physiol. 82 (2005) 233-239
3. Alderton W.K., Cooper C.E., and Knowles R.G. Nitric oxide synthases: structure, function and inhibition. Biochem. J. 357 (2001) 593-615
4. Ahlquist R.P. A study of the adrenotropic receptors. Am. J. Physiol. 153 (1948) 586-600
5. Chen Y.J., Shiao M.S., and Wang S.Y. The antioxidant caffeic acid phenethyl ester induces apoptosis associated with selective scavenging of hydrogen peroxide in human leukemic HL-60 cells. Anticancer Drugs 12 (2001) 143-149
6. Cheng J.T., Liu I.M., Tzeng T.F., Chen W.C., Hayakawa S., and Yamamoto T. Release of beta-endorphin by caffeic acid to lower plasma glucose in streptozotocin-induced diabetic rats. Horm. Metab. Res. 35 (2003) 251-258
7. Cicala C., Morello S., Iorio C., Capasso R., Borrelli F., and Mascolo N. Vascular effects of caffeic acid phenethyl ester (CAPE) on isolated rat thoracic aorta. Life Sci. 73 (2003) 73-80
8. 2. Role in vasodilatation. Cardiovasc. Res. 73 (2007) 424-431
9. Fesen M.R., Kohn K.W., Leteurtre F., and Pommier Y. Inhibitors of human immunodeficiency virus integrase. Proc. Natl. Acad. Sci. USA 90 (1993) 2399-2403
10. Fesen M.R., Pommier Y., Leteurtre E., Hiroguchi S., Yung J., and Kohn K.W. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem. Pharmacol. 48 (1994) 595-608
11. Ferreira S.H., Moncada S., and Vane J.R. Further experiments to establish that the analgesic action of asprin-like drugs depends on the inhibition of prostaglandin biosynthesis. Br. J. Pharmacol. 47 (1973) 629-630
12. Gerd W. The β-adrenergic receptors. Herz 27 (2002) 683-690
13. Govers R., and Rabelink T.J. Cellular regulation of endothelial nitric oxide synthase. Am. J. Physiol., Renal Physiol. 280 (2001) 193-206
14. Grunberger D., Banerjee R., Eisinger K., Oltz E.M., Efros L., Caldwell M., Estevez V., and Nakanishi K. Preferential cytotoxicity on tumor cells by caffeic acid phenethyl ester isolated from propolis. Experientia 44 (1988) 230-232
15. Hattori R., Sase K., Eizawa H., Kosuga K., Aoyama T., Inoue R., Sasayama S., Kawai C., Yui Y., Miyahara K., et al. Structure and function of nitric oxide synthases. Int. J. Cardiol. 51 (1995) 107
16. Howell R.E., Albeda S.M., Daise M.L., and Levine E.M. Characterization of β-adrenergic receptors in cultured human and bovine endothelial cells. J. Appl. Physiol. 65 (1988) 1251-1257
17. Huang S.S., Liu S.M., Lin S.M., Liao P.H., Lin R.H., Chen Y.C., Chih C.L., and Tsai S.K. Antiarrhythmic effect of caffeic acid phenethyl ester (CAPE) on myocardial ischemia/reperfusion injury in rats. Clin. Biochem. 38 (2005) 943-947
18. Ignarro L.J., Buga G.M., Wood K.S., Byrns R.E., and Chaudhuri G. Endothelium derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Natl. Acad. Sci. USA 84 (1987) 9265-9269
19. Ilhan A., Koltuksuz U., Ozen S., Uz E., Ciralik H., and Akyol O. The effects of caffeic acid phenethyl ester (CAPE) on spinal cord ischemia/reperfusion injury in rabbits. Eur. J. Cardio-thorac. Surg. 16 (1999) 458-463
20. Jiang C., Sarrel P.M., Lindsay D.C., Poole-Wilson P.A., and Collins P. Endothelium-independent relaxation of rabbit coronary artery by 17-oestradiol in vitro. Br. J. Pharmacol. 104 (1991) 1033-1037
21. 2+ channels by cAMP and cGMP in vascular smooth muscle cells. Circ. Res. 73 (1993) 1128-1137
22. Kelly R.A., Balligand J.L., and Smith T.W. Nitric oxide and cardiac function. Circ. Res. 79 (1996) 363-380
23. Kobilka B. Molecular and cellular biology of adrenergic receptors. Trends Cardiovasc. Med. 1 (1991) 189-194
24. Koltuksuz U., Ozen S., Uz E., Aydinc M., Karaman A., Gultek A., Akyol O., Gursoy M.H., and Aydin E. Caffeic acid phenethyl ester prevents intestinal reperfusion injury in rats. J. Pediatr. Surg. 34 (1999) 1458-1462
25. Kuriyama H., Ito Y., Suzuki H., Kitamura K., and Itoh T. Factors modifying contraction-relaxation cycle in vascular smooth muscles. Am. J. Physiol. 243 (1982) 641-642
26. Lee Y.J., Liao W.K., Chen W.K., and Yang C.C. Preferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells. Cancer Lett. 153 (2000) 51-56
27. + current in pituitary GH3 cells. J. Biol. Chem. 279 (2004) 26885-26892
28. Liu I.M. Stimulatory effect of caffeic acid on alpha1A-adrenoceptors to increase glucose uptake into cultured C2C12 cells. Naunyn-Schmiedeberg's Arch. Pharmacol. 362 (2000) 122-127
29. Martin W., Villani G.M., Jothianandan D., and Furchgott R.F. Selective blockage of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta. J. Pharmacol. Exp. Ther. 232 (1985) 708-716
30. Mazumder A., Raghavan K., Weinstein J., Kohn K.W., and Pommier Y. Inhibition of human immunodeficiency virus type-l integrase by curcumin. Biochem. Pharmacol. 49 (1995) 1165-1170
31. Michaluart P., Masferrer J.L., Carothrs A.M., Subbaramaiah K., Zweifeil B.S., Koboldt C., Mestre J.R., Grunberger D., Sacks P.G., Tanabe T., and Dannenberg A.J. Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation. Cancer Res. 59 (1999) 2347-2352
32. Miura H., Liu Y., and Gutterman D.D. Human coronary arteriolar dilation to bradykinin depends on membrane hyperpolarization. Circulation 99 (1999) 3132-3138
33. Molenaar P., Malta E., Jones C.R., Buxton B.F., and Summers R.J. Autoradiographic localization and function of β-adrenoceptors on the human internal mammary artery and sapharous vein. Br. J. Pharmacol. 95 (1988) 225-233
34. Mollaoglu H., Gokcimen A., Ozguner F., Oktemd F., Koyu A., Kocak A., Demirin H., Gokalp O., and Cicek E. Caffeic acid phenethyl ester prevents cadmium-induced cardiac impairment in rat. Toxicology 227 (2006) 15-20
35. Najibi S., and Cohen R.A. Enhanced role of potassium channels in relaxation of hypercholesterolemic rabbit carotid artery to nitric oxide. Am. J. Physiol. 38 (1995) H805-H811
36. Natarajan K., Singh S., Burke T.R., Grunberger D., and Aggarwal B.B. Caffeic acid phenethyl ester is a potent specific inhibitor of activation of nuclear transcription factor NF-κB. Immunology 93 (1996) 9090-9095
37. Nelson M.T., and Quayle J.M. Physiological roles and properties of potassium channels in arterial smooth muscle. Am. J. Physiol. 268 (1995) 799-822
38. Nelson M.T., Cheng H., Rubart M., Santana L.F., Bonev A.D., Knot H.J., and Lederer W.J. Relaxation of arterial smooth muscle by calcium sparks. Science 270 (1995) 633-637
39. Nishimura J., Kanaide H., and Nakamura M. Characteristics of adrenoceptors and [3H]nitrendipine receptors of porcine vascular smooth muscle: differences between coronary artery and aorta. Circ. Res. 60 (1987) 837-844
40. Noelker C., Bacher M., Gocke P., Weib X., Klockgether T., Du Y., and Dodel R. The flavanoide caffeic acid phenethyl ester blocks 6-hydroxydopamine-induced neurotoxicity. Neurosci. Lett. 383 (2005) 39-43
41. Orban Z., Mitsiades N., Burke T.R., Tsokos M., and Chrousos G.P. Caffeic acid phenethyl ester induces leukocyte apoptosis modulates nuclear factor-kappa B and suppresses acute inflammation. Neuroimmunomodulation 7 (2000) 99-105
42. Otter D., and Austin C. Effects of 17 β-oestradiol on rat isolated coronary and mesenteric artery tone: involvement of nitric oxide. J. Pharm. Pharmacol. 50 (1990) 531-538
43. Ozyurt H., Irmak M.K., Akyol O., and Sogut S. Caffeic acid phenethyl ester changes the indices of oxidative stress in serum of rats with renal ischaemia-reperfusion injury. Cell Biochem. Funct. 19 (2001) 259-263
44. Park E.H., and Kahng J.H. Suppressive effects of propolis in rat adjuvant arthritis. Arch. Pharm. Res. 22 (1999) 554-558
45. Park J.H., Lee J.K., Kim H.S., Chung S.T., Eom J.H., Kim K.A., Chung S.J., Paik S.Y., and Oh H.Y. Immunomodulatory effect of caffeic acid phenethyl ester in Balb/c mice. Int. Immunopharmacol. 4 (2004) 429-436
46. Pascual C., Gonzales R., and Torricella R.G. Scavenging action of propolis extract agents oxygen radicals. J. Ethnopharmacol. 41 (1994) 9-13
47. Perez G.J., Bonev A.D., Patlak J.B., and Nelson M.T. Functional coupling of ryanodine receptors to KCa channels in smooth muscle cells from rat cerebral arteries. J. Gen. Physiol. 113 (1999) 229-238
48. Rao C., Desai D., Kaul B., Amin S., and Reddy B.S. Effect of caffeic acid esters on carcinogen-induced mutagenicity and human colon adenocarcinoma cell growth. Chem. Biol. Interact. 84 (1992) 277-290
49. Rees D.D., Palmer R.M., Schulz R., Hodson H.F., and Moncada S. Charaterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br. J. Pharmacol. 101 (1990) 746-752
50. Rezzani R., Giugno L., Buffoli B., Bonomini F., and Bianchi R. The protective effect of caffeic acid phenethyl ester against cyclosporine A-induced cardiotoxicity in rats. Toxicology 212 (2005) 155-164
51. Schwartz J., and Velly J. The beta-adrenoceptor of pig coronary arteries: determination of beta 1 and beta 2 subtypes by radioligand binding. Br. J. Pharmacol. 79 (1983) 409-414
52. Ca channels in oral keratinocytes. J. Dent. Res. 84 (2005) 468-473
53. Song Y.S., Park E.H., Hur G.M., Ryu Y.S., Lee Y.S., Lee J.Y., Kim Y.M., and Jin C. Caffeic acid phenethyl ester inhibits nitric oxide synthase gene expression and enzyme activity. Cancer Lett. 175 (2002) 53-61
54. Sud'ina G.F., Mirzoeva O.K., Pushkareva G.A., Korshunova G.A., Sumbatyan N.V., and Varfolomeev S.D. Caffeic acid phenetyl ester as a lipoxygenase inhibitor with antioxidant properties. FEBS Lett. 329 (1993) 21-24
55. Takeda H., Tsuji M., Miyamoto J., Masuya J., Iimori M., and Matsumiya T. Caffeic acid produces antidepressive- and/or anxiolytic-like effects through indirect modulation of the alpha 1A-adrenoceptor system in mice. Neuroreport 23 (2003) 1067-1070
56. Xu P.H., Long Y., Dai F., and Liu Z.L. The relaxant effect of curcumin on porcine coronary arterial ring segments. Vasc. Pharmacol. 47 (2007) 25-30
57. Wang Y., and Marsden P.A. Nitric oxide synthases: gene structure and regulation. Adv. Pharmacol. 34 (1995) 71-90
58. Wei X., Zhao L., Ma Z., Holtzman D.M., Yan C., Dodel R.C., Hampel H., Oertel W., Farlow M.R., and Du Y. Caffeic acid phenethyl ester prevents neonatal hypoxic-ischaemic brain injury. Brain 127 (2004) 2629-2635
59. Yamada S., Kashiwabara T., Yamazawa T., Harada Y., and Nakayama K. Demonstration of beta 1-adrenoceptor mediating relaxation of porcine coronary artery by radioligand binding and pharmacological methods. Life Sci. 43 (1988) 1999-2006