Synthesis and biological evaluation of some new N4-substituted isatin-3-thiosemicarbazones

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 24, Issue 2, 2009, Pages 437-446

  Pervez, Humayun ^a   Chohan, Zahid Hussain ^a   Ramzan, Muhammad ^a   Nasim, Faiz Ul Hassan ^b   Khan, Khalid Mohammed ^c  

^a BAHAUDDIN ZAKARIYA UNIVERSITY   (Pakistan)

^b THE ISLAMIA UNIVERSITY OF BAHAWALPUR   (Pakistan)

^c UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

Cytotoxicity; Isatin; Phytotoxicity; Soil ureases inhibitors; Thiosemicarbazones; Urease inhibition

Indexed keywords

2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) N (2,4,6 TRICHLOROPHENYL) 1 HYDRAZINECARBOTHIOAMIDE; 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) N [2 (TRIFLUOROMETHOXY)PHENYL] 1 HYDRAZINECARBOTHIOAMIDE; 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) N [2 (TRIFLUOROMETHYL)PHENYL] 1 HYDRAZINECARBOTHIOAMIDE; 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) N [3 (TRIFLUOROMETHYL)PHENYL] 1 HYDRAZINECARBOTHIOAMIDE; 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) N [4 (TRIFLUOROMETHOXY)PHENYL] 1 HYDRAZINECARBOTHIOAMIDE; 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) N [4 (TRIFLUOROMETHYL)PHENYL] 1 HYDRAZINECARBOTHIOAMIDE; ISATIN 3 THIOSEMICARBAZONE DERIVATIVE; ISATIN DERIVATIVE; N (2 FLUOROPHENYL) 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) 1 HYDRAZINECARBOTHIOAMIDE; N (2,4 DIFLUOROPHENYL) 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) 1 HYDRAZINECARBOTHIOAMIDE; N (2,5 DIFLUOROPHENYL) 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) 1 HYDRAZINECARBOTHIOAMIDE; N (2,6 DIFLUOROPHENYL) 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) 1 HYDRAZINECARBOTHIOAMIDE; N (3 FLUOROPHENYL) 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) 1 HYDRAZINECARBOTHIOAMIDE; N (3,5 DIFLUOROPHENYL) 2 (2 OXO 1,2 DIHYDRO 3H INDOL 3 YLIDENE) 1 HYDRAZINECARBOTHIOAMIDE; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG; UREASE INHIBITOR; ENZYME INHIBITOR; ISATIN; UREASE;

ARTEMIA; ARTICLE; BIOASSAY; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ASSAY; ENZYME INHIBITION; IC 50; IN VITRO STUDY; LD 50; NONHUMAN; PHYTOTOXICITY; PRIORITY JOURNAL; ANIMAL; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; METABOLISM; SYNTHESIS;

ARTEMIA;

ANIMALS; ARTEMIA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; ISATIN; THIOSEMICARBAZONES; UREASE;

EID: 68049106216     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360802188420     Document Type: Article

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