Genetic biomonitoring of an urban population exposed to mutagenic airborne pollutants

Environment International

Volumn 35, Issue 7, 2009, Pages 1023-1029

  Coronas, Mariana V ^a,b   Pereira, Tatiana S ^a,b   Rocha, Jocelita A V ^a   Lemos, Andréia T ^a   Fachel, Jandyra M G ^b   Salvadori, Daisy M F ^c   Vargas, Vera M F ^a,b  

^a Fundacao Estadual de Protecao Ambiental Henrique Luis Roessler   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Air pollution; Biomonitoring; Comet assay; Genotoxicity; Micronucleus assay; Salmonella microsome assay

Indexed keywords

AIR POLLUTION; AMINES; CELL CULTURE; DICHLOROMETHANE; DNA; ELECTROPHORESIS; HEALTH RISKS; PETROLEUM REFINERIES; REFINING; SALMONELLA;

AIRBORNE PARTICULATE MATTERS; ATMOSPHERIC ENVIRONMENT; BIOMONITORING; COMET ASSAYS; ENVIRONMENTAL CONTAMINANT; ENVIRONMENTAL POLLUTIONS; GENOTOXICITIES; SINGLE CELL GEL ELECTROPHORESIS;

POLLUTION;

AROMATIC AMINE; AROMATIC NITRO COMPOUND; MUTAGENIC AGENT; ORGANIC MATTER;

ASSAY; ATMOSPHERIC POLLUTION; BIOMARKER; BIOMONITORING; DNA; GENOTOXICITY; MUTAGENICITY; PARTICULATE MATTER; POLLUTION EXPOSURE; URBAN POPULATION;

ADULT; AIR POLLUTION; ARTICLE; BIOLOGICAL MONITORING; BLOOD CELL; BRAZIL; CONTROLLED STUDY; DNA DAMAGE; DNA DETERMINATION; ENVIRONMENTAL EXPOSURE; GENOTOXICITY; HUMAN; HUMAN CELL; LYMPHOCYTE; MALE; MICROSOME; MUCOSA CELL; NONHUMAN; OIL INDUSTRY; PARTICULATE MATTER; PRIORITY JOURNAL; SMOKING HABIT; URBAN AREA; URBAN POPULATION;

BRAZIL; SOUTH AMERICA;

NICOTIANA TABACUM;

EID: 68049105275     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2009.05.001     Document Type: Article

References (54)

1. Bamford H.A., Bezabeh D.Z., Schantz S., Wise S.A., and Baker J.E. Determination and comparison of nitrated-polycyclic aromatic hydrocarbons measured in air and diesel particulate reference materials. Chemosphere 50 (2003) 575-587
2. Bernstein L., Kaldor J., McCann J., and Pike M.C. An empirical approach to the statistical analysis of mutagenesis data from the Salmonella test. Mutat Res 97 (1982) 267-281
3. Binková B., Lewtas J., Miskova I., Pössner P., Cerná M., Mráckova G., et al. Biomarker studies in Northern Bohemia. Environ Health Perspect 4 (1996) 591-597
4. Bonassi S., Neri M., Lando C., Ceppi M., Lin Y.P., Chang W.P., et al. Effect of smoking habit on the frequency of micronuclei in human lymphocytes: results from the human micronucleus project. Mutat Res 543 (2003) 155-166
5. BRASIL. Conselho Nacional do Meio Ambiente. Resolução CONAMA n○ 003. Padrões Nacionais de Qualidade do Ar. Diário Oficial da República Federativa do Brasil. Brasília. 28 June 1990. 15937-15939.
6. Bräuner E.V., Forchhammer L., Möller P., Simonsen J., Glasius M., Wåhlin P., et al. Exposure to ultrafine particles from ambient air and oxidative stress-induced DNA damage. Environ Health Perspect 115 (2007) 1177-1182
7. Chen C., Arjomandi M., Qin H., Balmes J., Tager I., and Holland N. Cytogenetic damage in buccal epithelia and peripheral lymphocytes of young healthy individuals exposed to ozone. Mutagenesis 21 (2006) 131-137
8. Claxton L.D., and Woodall Jr. G.M. A review of the mutagenicity and rodent carcinogenicity of ambient air. Mutat Res 636 (2007) 36-94
9. Claxton L.D., Matthews P.P., and Warren S.H. The genotoxicity of ambient outdoor air, a review: Salmonella mutagenicity. Mutat Res 567 (2004) 347-399
10. Collins A.R. The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol 26 (2004) 249-261
11. Collins A.R., Dobson V.L., Dusinska M., Kennedy G., and Stetina R. The comet assay: what can it really tell us?. Mutat Res 375 (1997) 183-193
12. Coronas M.V., Horn R.C., Ducatti A., Rocha J.A.V., and Vargas V.M.F. Mutagenic activity of airborne particulate matter in petrochemical industrial area. Mutat Res 650 (2008) 196-201
13. Costa C., Teixeira J.P., Silva S., Roma-Torres J., Coelho P., Gaspar J., et al. Cytogenetic and molecular biomonitoring of a Portuguese population exposed to pesticides. Mutagenesis 21 (2006) 343-350
14. Curtis L., Rea W., Smith-Willis P., Fenyves E., and Pan Y. Adverse health effects of outdoor air pollutants. Environ Int 32 (2006) 815-830
15. De Martinis B.S., Kado N.Y., Carvalho L.R.F., Okamoto R.A., and Gundel L.A. Genotoxicity of fractionated organic material in airborne particles from São Paulo, Brazil. Mutat Res 446 (1999) 83-94
16. Ducatti A., and Vargas V.M.F. Mutagenic activity of airborne particulate matter as an indicative measure of atmospheric pollution. Mutat Res 540 (2003) 67-77
17. Dusinska M., and Collins A.R. The comet assay in human biomonitoring: gene-environment interactions. Mutagenesis 23 (2008) 191-205
18. Faust F., Kassie F., Knasmuller S., Boedecker R.H., Mann M., and Mersch-Sundermann V. The use of the alkaline comet assay with lymphocytes in human biomonitoring studies. Mutat Res 566 (2004) 209-229
19. Fenech M., Holland N., Chang W.P., Zeiger E., and Bonassi S. The HUman MicroNucleus Project - an international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans. Mutat Res 428 (1999) 271-283
20. Finlayson-Pitts B.J., and Pitts J.N. Tropospheric air pollution: ozone, airborne toxics, polycyclic aromatic hydrocarbons, and particles. Science 276 (1997) 1045-1052
21. Holland N., Bolognesi C., Kirsch-Volders M., Bonassi S., Zeiger E., Knasmueller S., et al. The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps. Mutat Res 659 (2008) 1-193
22. Kado N.Y., Guirguis N., Guirguis C., Flessel P., Chan R.C., Chang K., et al. Mutagenicity of fine (< 2.5 μm) airborne particles: diurnal variation in community air determined by a Salmonella micro preincubation (microsuspension) procedure. Environ Mutagen 8 (1986) 53-66
23. Kassie F., Parzefall W., and Knasmüller S. Single cell gel electrophoresis assay: a new technique for human biomonitoring studies. Mutat Res 463 (2000) 13-31
24. Lewtas J. Air pollution combustion emissions: characterization of causative agents and mechanisms associated with cancer, reproductive, and cardiovascular effects. Mutat Res 636 (2007) 95-133
25. Majer B.J., Laky B., Knasmüller S., and Kassie F. Use of the micronucleus assay with exfoliated epithelial cells as a biomarker for monitoring individuals at elevated risk of genetic damage and in chemoprevention trials. Mutat Res 489 (2001) 147-172
26. Maluf S.W., Passos D.F., Bacelar A., Speit G., and Erdtmann B. Assessment of DNA damage in lymphocytes of workers exposed to X-radiation using the micronucleus test and the comet assay. Environ Mol Mutagen 38 (2001) 311-315
27. Maron D.M., and Ames B.N. Revised methods for the Salmonella mutagenicity test. Mutat Res 113 (1983) 173-215
28. Marvin C.H., and Hewitt L.M. Analytical methods in bioassay-directed investigations of mutagenicity of air particulate material. Mutat Res 636 (2007) 4-35
29. Möller P. The alkaline comet assay: towards validation in biomonitoring of DNA damaging exposures. Basic Clin Pharmacol Toxicol 98 (2006) 336-345
30. Möller P., Knudsen L.E., Loft S., and Wallin H. The comet assay as a rapid test in biomonitoring occupational exposure to DNA-damaging agents and effect of confounding factors. Cancer Epidemiol Biomark Prev 9 (2000) 1005-1015
31. Nadal M., Mari M., Schuhmacher M., and Domingo J.L. Multi-compartmental environmental surveillance of a petrochemical area: levels of micropollutants. Environ Int 35 (2009) 227-235
32. Nersesyan A., Kundi M., Atefie K., Schulte-Hermann R., and Kanasmüller S. Effect of staining procedures on the results of micronucleus assays with exfoliated oral mucosa cells. Cancer Epidemiol Biomarkers Prev 15 (2006) 1835-1840
33. Novotna B., Topinka J., Solansky I., Chvatalova I., Lnenickova Z., and Sram R.J. Impact of air pollution and genotype variability on DNA damage in Prague policemen. Toxicol Lett 172 (2007) 37-47
34. Peluso M., Srivatanakul P., Munnia A., Jedpiyawongse A., Meunier A., Sangrajrang Piro S., et al. DNA adduct formation among workers in a Thai industrial estate and nearby residents. Sci Total Environ 389 (2008) 283-288
35. Proia N.K., Paszkiewicz G.M., Nasca M.A.S., Franke G.E., and Pauly J.L. Smoking and smokeless tobacco-associated human buccal cell mutations and their association with oral cancer-a review. Cancer Epidemiol Biomarkers Prev 15 (2006) 1061-1077
36. Remor A.P., Totti C.C., Moreira D.A., Dutra G.P., Heuser V.D., and Boeira J.M. Occupational exposure of farm workers to pesticides: Biochemical parameters and evaluation of genotoxicity. Environ Int 35 (2009) 273-278
37. Rojas E., Lopez M.C., and Valverde M. Single cell gel electrophoresis assay: methodology and applications. J Chromatogr B 722 (1999) 225-254
38. Roma-Torres J., Teixeira J.P., Silva S., Laffon B., Cunha L.M., Méndez J., et al. Evaluation of genotoxicity in a group of workers from a petroleum refinery aromatics plant. Mutat Res 604 (2006) 19-27
39. Singh N.P., Mccoy M.T., Tice R.R., and Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175 (1988) 184-191
40. Skarek M., Janosek J., Cupr P., Kohoutek J., Novotna-Rychetska A., and Holoubek I. Evaluation of genotoxic and non-genotoxic effects of organic air pollution using in vitro bioassays. Environ Int 33 (2007) 859-866
41. Sram R.J., Podrazilova K., Dejmek J., Mrackova G., and Pilcik T. Single cell gel electrophoresis assay: sensitivity of peripheral white blood cells in human population studies. Mutagenesis 13 (1998) 99-103
42. Tice R.R., Agurell E., Anderson D., Burlinson B., Hartmann A., Kobayashi H., et al. Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 35 (2000) 206-221
43. Tolbert P., Shy C., and Allen J. Micronuclei and other nuclear anomalies in buccal smears: methods development. Mutat Res 271 (1992) 69-77
44. Tovalin H., Valverde M., Morandi M.T., Blanco S., Whitehead L., and Rojas E. DNA damage in outdoor workers occupationally exposed to environmental air pollutants. Occup Environ Med 63 (2006) 230-236
45. Traversi D., Degan R., De Marco R., Gilli G., Pignata C., Ponzio M., et al. Mutagenic properties of PM2.5 air pollution in the Padana Plain (Italy) before and in the course of XX Winter Olympic Games of "Torino 2006". Environ Int 34 (2008) 966-970
46. Valverde M., and Rojas E. Environmental and occupational biomonitoring using the Comet assay. Mutat Res 681 (2009) 93-109
47. Valverde M., Delcarmenlopez M., Lopez I., Sanchez I., Fortoul T.I., Ostrosky-Wegman P., et al. DNA damage in leukocytes and buccal and nasal epithelial cells of individuals exposed to air pollution in Mexico City. Environ Mol Mutagen 30 (1997) 147-152
48. Vargas V.M.F. Mutagenic activity as a parameter to assess ambient air quality for protection of the environment and human health. Mutat Res 544 (2003) 313-319
49. Vargas V.M.F., Horn R.C., Guidobono R.R., Mittelstaedt A.B., and Azevedo I.G. Mutagenic activity of airborne particulate matter from the urban area of Porto Alegre. Genet Mol Biol 21 (1998) 247-253
50. Vineis P., and Husgafvel-Pursiainen K. Air pollution and cancer: biomarker studies in human populations. Carcinogenesis 26 (2005) 1846-1855
51. Watanabe M., Ishidate Jr. M., and Nohmi T. A sensitive method for the detection of mutagenic nitroarenes: construction of nitroreductase-overproducing derivates of Salmonella typhimurium strains TA98 and TA100. Mutat Res 216 (1989) 211-220
52. Watanabe M., Ishidate Jr. M., and Nohmi T. Sensitive method for the detection of mutagenic nitroarenes and aromatic amines: new derivates of Salmonella typhimurium tester strains possessing elevated O-acetyltransferase levels. Mutat Res 234 (1990) 337-348
53. WHO World Health Organization. Air quality guidelines for particulate matter, ozone, nitrogen dioxide and sulfur dioxide; Global update 2005 (2006), WHO, Geneva
54. Zwozdziak J., Jadczyk P., and Kucharczyk J. Seasonal variability of the mutagenicity of airborne particles in the town center. J Aerosol Sci 32 (2001) 409-423