Effect of cervical spinal cord hemisection on the expression of axon growth markers

Neuroscience Letters

Volumn 462, Issue 3, 2009, Pages 276-280

  Vinit, Stéphane ^a   Darlot, Fannie ^a   Stamegna, Jean Claude ^a   Gauthier, Patrick ^a   Kastner, Anne ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Axon growth markers; GAP 43; Plasticity; Spinal cord injury

Indexed keywords

BETA TUBULIN; BIOLOGICAL MARKER; NEUROMODULIN;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CERVICAL SPINAL CORD INJURY; CONTROLLED STUDY; FEMALE; HISTOLOGY; IMMUNOHISTOCHEMISTRY; NERVE CELL PLASTICITY; NERVE FIBER GROWTH; NERVE SPROUTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD HEMISECTION; SPINAL CORD VENTRAL HORN; WESTERN BLOTTING;

ANIMALS; AXONS; BIOLOGICAL MARKERS; FEMALE; GAP-43 PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL CORD INJURIES; TUBULIN;

EID: 68049092909     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.06.058     Document Type: Article

References (39)

1. Arvanian V.L., Schnell L., Lou L., Golshani R., Hunanyan A., Ghosh A., Pearse D.D., Robinson J.K., Schwab M.E., Fawcett J.W., and Mendell L.M. Chronic spinal hemisection in rats induces a progressive decline in transmission in uninjured fibers to motoneurons. Exp. Neurol. 216 (2009) 471-480
2. Ballermann M., and Fouad K. Spontaneous locomotor recovery in spinal cord injured rats is accompanied by anatomical plasticity of reticulospinal fibers. Eur. J. Neurosci. 23 (2006) 1988-1996
3. Bareyre F.M., Haudenschild B., and Schwab M.E. Long-lasting sprouting and gene expression changes induced by the monoclonal antibody IN-1 in the adult spinal cord. J. Neurosci. 22 (2002) 7097-7110
4. Bareyre F.M., Kerschensteiner M., Raineteau O., Mettenleiter T.C., Weinmann O., and Schwab M.E. The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats. Nat. Neurosci. 7 (2004) 269-277
5. Benowitz L.I., and Routtenberg A. GAP-43: an intrinsic determinant of neuronal development and plasticity. Trends Neurosci. 20 (1997) 84-91
6. Blesch A., and Tuszynski M.H. Spinal cord injury: plasticity, regeneration and the challenge of translational drug development. Trends Neurosci. 32 (2009) 41-47
7. Boulenguez P., Gauthier P., and Kastner A. Respiratory neuron subpopulations and pathways potentially involved in the reactivation of phrenic motoneurons after C2 hemisection. Brain Res. 1148 (2007) 96-104
8. Bradbury E.J., Moo L.D.F., Popat R.J., King V.R., Bennett G.S., Patel P.N., Fawcett J.W., and McMahon S.B. Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature 416 (2002) 636-640
9. Carmel J.B., Galante A., Soteropoulos P., Tolias P., Recce M., Young W., and Hart R.P. Gene expression profiling of acute spinal cord injury reveals spreading inflammatory signals and neuron loss. Physiol. Genomics 7 (2001) 201-213
10. Ching Y.P., Averill S., Wilkin G.P., Wotherspoon G., and Priestley J.V. Serotoninergic terminals express a growth associated protein (GAP-43) in the adult rat spinal cord. Neurosci. Lett. 167 (1994) 67-72
11. Courtine G., Song B., Roy R.R., Zhong H., Herrmann J.E., Ao Y., Qi J., Edgerton V.R., and Sofroniew M.V. Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury. Nat. Med. 14 (2008) 69-74
12. Curtis R., Averill S., Priestley J.V., and Wilkin G.P. The distribution of GAP-43 in normal rat spinal cord. J. Neurocytol. 22 (1993) 39-50
13. Dergham P., Ellenzam B., Essagian C., Avedissian H., Lubell W.D., and McKerracher L. Rho signalling pathway targeted to promote spinal cord repair. J. Neurosci. 22 (2002) 6570-6577
14. Fernandes K.J.L., Fan D.P., Tsui B.J., Cassar S.L., and Tetzlaff W. Influence of the axotomy to the cell body distance in rat rubrospinal and spinal motoneurons: differential regulation of GAP-43, tubulins, and Neurofilament-M. J. Comp. Neurol. 414 (1999) 495-510
15. Fouad K., Pedersen V., Schwab M.E., and Brösamle C. Cervical sprouting of corticospinal fibers after thoracic spinal cord injury accompanies shifts in evoked motor responses. Curr. Biol. 11 (2001) 1766-1770
16. Goldstein B., Little J.W., and Harris R.M. Axonal sprouting following incomplete spinal cord injury: an experimental model. J. Spinal Cord Med. 20 (1997) 200-206
17. Gomez-Pinilla F., Ying Z., Roy R.R., Hodgson J., and Edgerton V.R. Afferent input modulates neurotrophins and synaptic plasticity in the spinal cord. J. Neurophysiol. 92 (2004) 3423-3432
18. Goshgarian H.G. The crossed phrenic phenomenon: a model for plasticity in the respiratory pathways following spinal cord injury. J. Appl. Physiol. 94 (2003) 795-810
19. Han P.J., Shukla S., Subramanian P.S., and Hoffman P.N. Cyclic AMP elevates tubulin expression without increasing intrinsic axon growth capacity. Exp. Neurol. 189 (2004) 293-302
20. Lane M.A., Fuller D.D., White T.E., and Reier P.J. Respiratory neuroplasticity and cervical spinal cord injury: translational perspectives. Trends Neurosci. 31 (2008) 538-547
21. Lipski J.X., Zhang B., Kruszewska B., and Kanjhan R. Morphological study of long axonal projections of ventral medullary inspiratory neurons in the rat. Brain Res. 640 (1994) 171-184
22. Liu H.H., and Brady S.T. cAMP, tubulin, axonal transport and regeneration. Exp. Neurol. 189 (2004) 199-203
23. Liu N.K., and Xu X.M. β tubulin is a more suitable internal control than β actin in western blot analysis of spinal cord tissues after traumatic injury. J. Neurotrauma 23 (2006) 1794-1801
24. Lund L.M., and McQuarrie I.G. Axonal regrowth upregulates beta-actin and Jun D mRNA expression. J. Neurobiol. 31 (1996) 476-486
25. Oestreicher A.B., De Graan P.N.E., Gispen W.H., Verhaagen J., and Schrama L.H. B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system. Prog. Neurobiol. 53 (1997) 627-686
26. Ondarza A.B., Ye Z., and Hulsebosch C.E. Direct evidence of primary afferent sprouting in distant segments following spinal cord injury in the rat: colocalization of GAP-43 and CGRP. Exp. Neurol. 184 (2003) 373-380
27. Pearse D.D., Pereira F.C., Marcillo A.E., Bates M.L., Berrocal Y.A., Filbin M.T., and Bunge M.B. cAMP and schwann cells promote axonal growth and functional recovery after spinal cord injury. Nat. Med. 10 (2004) 610-616
28. Schreyer D.J., and Skene J.H.P. Fate of GAP-43 in ascending spinal axons of DRG neurons after peripheral nerve injury: delayed accumulation and correlation with regenerative potential. J. Neurosci. 11 (1991) 3738-3751
29. Soares S., Barnat M., Salim C., von Boxberg Y., Ravaille-Veron M., and Nothias F. Extensive structural remodeling of the injured spinal cord revealed by phosphorylated MAP1B in sprouting axons and degenerating neurons. Eur. J. Neurosci. 26 (2007) 1446-1461
30. Steward O., Zheng B., Tessier-Lavigne M., Hofstadter M., Sharp K., and Yee K.M. Regenerative growth of corticospinal tract axons via the ventral column after spinal cord injury in mice. J. Neurosci. 28 (2008) 6836-6847
31. Vinit S., Boulenguez P., Efthimiadi L., Stamegna J.C., Gauthier P., and Kastner A. Axotomized bulbospinal neurons express c-jun after cervical spinal cord injury. Neuroreport 16 (2005) 1535-1539
32. Vinit S., Gauthier P., Stamegna J.C., and Kastner A. High cervical lateral spinal cord injury results in long-term ipsilateral hemidiaphragm paralysis. J. Neurotrauma 23 (2006) 1137-1146
33. Vinit S., Stamegna J.C., Boulenguez P., Gauthier P., and Kastner A. Restorative respiratory pathways after partial cervical spinal cord injury: role of ipsilateral phrenic afferents. Eur. J. Neurosci. 25 (2007) 3551-3560
34. Vinit S., Darlot F., Stamegna J.C., Sanchez P., Gauthier P., and Kastner A. Long-term reorganization of respiratory pathways after partial cervical spinal cord injury. Eur. J. Neurosci. 27 (2008) 897-908
35. Weidner N., Ner A., Salimi N., and Tuszynski M.H. Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 3513-3518
36. Xiao H.S., Huang Q.H., Zhang F.X., Bao L., Lu Y.J., Guo C., Yang L., Huang W.J., Fu G., Xu S.H., Cheng X.P., Yan Q., Zhu Z.D., Zhang X., Chen Z., Han Z.G., and Zhang X. Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 8360-8365
37. Yang Y., Xie Y., Chai H., Fan M., Liu S., Liu H., Bruce I., and Wu W. Microarray analysis of gene expression patterns in adult spinal motoneurons after differents types of injuries. Brain Res. 1075 (2006) 1-12
38. Ying Z., Roy R.R., Edgerton V.R., and Gomez-Pinilla F. Exercise restores levels of neurotrophins and synaptic plasticity following spinal cord injury. Exp. Neurol. 193 (2005) 411-419
39. Zhang K.H., Xiao H.S., Lu P.H., Shi J., Li G.D., Wang Y.T., Han S., Zhang F.X., Lu Y.J., Zhang X., and Xu X.M. Differential gene expression after complete spinal cord transection in adult rats: an analysis focused on a subchronic post-injury stage. Neuroscience 128 (2004) 375-388