Long-term reorganization of respiratory pathways after partial cervical spinal cord injury

European Journal of Neuroscience

Volumn 27, Issue 4, 2008, Pages 897-908

  Vinit, Stéphane ^a,b   Darlot, Fannie ^a   Stamegna, Jean Claude ^a   Sanchez, Patrick ^a   Gauthier, Patrick ^a   Kastner, Anne ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Crossed phrenic pathways; Plasticity; Rat; Respiratory network; Rewiring; Spinal cord injury

Indexed keywords

GALLAMINE; NEUROMUSCULAR BLOCKING AGENT; NICOTINIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CERVICAL SPINAL CORD INJURY; CONTROLLED STUDY; FEMALE; INNERVATION; MOTONEURON; NEUROPATHOLOGY; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL; RAT; RESPIRATORY NERVE CELL;

AFFERENT PATHWAYS; ANIMALS; CERVICAL VERTEBRAE; DIAPHRAGM; ELECTROPHYSIOLOGY; FEMALE; FUNCTIONAL LATERALITY; PHRENIC NERVE; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY PARALYSIS; SPINAL CORD INJURIES; TIME;

EID: 40549102232     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2008.06072.x     Document Type: Article

References (34)

1. Aoki, M., Fujito, Y., Satomi, H., Kurosawa, Y. Kasaba, T. (1986) The possible role of collateral sprouting in the functional restitution of corticospinal connections after spinal hemisection. Neurosci. Res., 3, 617 627.
2. Bareyre, F.M. (2008) Neuronal repair and replacement in spinal cord injury. J. Neurol. Sci., 265, 63 72.
3. Bareyre, F.M., Kerschensteiner, M., Raineteau, O., Mettenleiter, T.C., Weinmann, O. Schwab, M.E. (2004) The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats. Nat. Neurosci., 7, 269 277.
4. Boulenguez, P., Gauthier, P. Kastner, A. (2007) Respiratory neuron subpopulations and pathways potentially involved in the reactivation of phrenic motoneurons after C2 hemisection. Brain Res., 1148, 96 104.
5. Dobbins, E.G. Feldman, J.L. (1994) Brainstem network controlling descending drive to phrenic motoneurons in rat. J. Comp. Neurol., 347, 64 86.
6. Duffin, J. Li, Y.M. (2006) Transmission of respiratory rhythm: midline-crossing connections at the level of the phrenic motor nucleus? Respir. Physiol. Neurobiol., 153, 139 147.
7. Feldman, J.L., Loewy, A.D. Speck, D.F. (1985) Projections from the ventral respiratory group to phrenic and intercostals motoneurons in cat: an autoradiographic study. J. Neurosci., 5, 1993 2000.
8. Forster, H.V. (2003) Plasticity in the control of breathing following sensory denervation. J. Appl. Physiol., 94, 784 794.
9. Fouad, K., Pedersen, V., Schwab, M.E. Brösamle, C. (2001) Cervical sprouting of corticospinal fibers after thoracic spinal cord injury accompanies shifts in evoked motor responses. Curr. Biol., 11, 1766 1770.
10. Fuller, D.D., Golder, F.J., Olson, E.B. Jr. Mitchell, G.S. (2006) Recovery of phrenic activity and ventilation after cervical spinal hemisection in rats. J. Appl. Physiol., 100, 800 806.
11. Golder, F.J., Fuller, D.D., Davenport, P.W., Johnson, R.D., Reier, P.J. Bolser, D.C. (2003) Respiratory motor recovery after unilateral spinal cord injury: eliminating crossed phrenic activity decreases tidal volume and increases contralateral respiratory motor output. J. Neurosci., 23, 2494 2501.
12. Golder, F.J. Mitchell, G.S. (2005) Spinal synaptic enhancement with acute intermittent hypoxia improves respiratory function after chronic cervical spinal cord injury. J. Neurosci., 25, 2925 2932.
13. Golder, F.J., Reier, P.J. Bolser, D.C. (2001) Altered respiratory motor drive after spinal cord injury: supraspinal and bilateral effects of a unilateral lesion. J. Neurosci., 21, 8680 8689.
14. Goshgarian, H.G. (2003) The crossed phrenic phenomenon: a model for plasticity in the respiratory pathways following spinal cord injury. J. Appl. Physiol., 94, 795 810.
15. Goshgarian, H.G., Ellenberger, H.H. Feldman, J.L. (1991) Decussation of bulbospinal respiratory axons at the level of the phrenic nuclei in adult rats: a possible substrate for the crossed phrenic phrenomenon. Exp. Neurol., 111, 135 139.
16. Hagg, T. (2006) Collateral sprouting as a target for improved function after spinal cord injury. J. Neurotrauma, 23, 281 294.
17. Hagg, T. Oudega, M. (2006) Degenerative and spontaneous regenerative processes after spinal cord injury. J. Neurotrauma, 3/4, 264 280.
18. Li, Y., Decherchi, P. Raisman, G. (2003) Transplantation of olfactory ensheathing cells into spinal cord lesions restores breathing and climbing. J. Neurosci., 23, 727 731.
19. Li, W.W.Y., Yem, D.T.W., Chuah, M.I., Leung, P.C. Tsang, D.S.C. (1994) Axonal sprouting in the hemisected adult rat spinal cord. Neuroscience, 61, 133 139.
20. Lipski, J.X., Zhang, B., Kruszewska, B. Kanjhan, R. (1994) Morphological study of long axonal projections of ventral medullary inspiratory neurons in the rat. Brain Res., 640, 171 184.
21. Mantilla, C.B., Rowley, K.L., Zhan, W.Z., Fahim, M.A. Sieck, G.C. (2007) Synaptic vesicle pools at diaphragm neuromuscular junctions vary with motoneuron soma, not axon terminal inactivity. Neuroscience, 146, 178 189.
22. Minor, H.K., Akison, L.K., Goshgarian, H.G. Seeds, N.W. (2006) Spinal cord injury-induced plasticity in the mouse: the crossed phrenic phenomenon. Exp. Neurol., 200, 486 495.
23. Mitchell, G.S. Johnson, S.M. (2003) Neuroplasticity in respiratory motor control. J. Appl. Physiol., 94, 358 374.
24. Miyata, H., Zhan, W.Z., Prakash, Y.S. Sieck, G.C. (1995) Myoneural interactions affect diaphragm muscle adaptations to inactivity. J. Appl. Physiol., 79, 1640 1649.
25. Moreno, D.E., Yu, X. J. Goshgarian, H.G. (1992) Identification of the axon pathways which mediate functional recovery of a paralyzed hemidiaphragm following spinal cord hemisection in the adult rat. Exp. Neurol., 116, 219 228.
26. Morris, K.F., Baekey, D.M., Nuding, S.C., Dick, T.E., Shannon, R. Lindsey, B.G. (2003) Neural network plasticity in respiratory control. J. Appl. Physiol., 94, 1242 1252.
27. Nantwi, K.D., El-Bohy, A.A., Schrimsher, G.W., Reier, P.J. Goshgarian, H.G. (1999) Spontaneous functional recovery in a paralyzed hemidiaphragm following upper cervical spinal cord injury in adult rats. Neurorehab. Neural Report, 13, 225 234.
28. O'Hara, T.E. Goshgarian, H.G. (1991) Quantitative assessment of phrenic nerve functional recovery mediated by the crossed phrenic reflex at various time intervals after spinal cord injury. Exp. Neurol., 111, 244 250.
29. Oo, T., Watt, J.W., Soni, B.M. Sett, P.K. (1999) Delayed diaphragm recovery in 12 patients after high cervical spinal cord injury. A retrospective review of the diaphragm status of 107 patients ventilated after acute spinal cord injury. Spinal Cord, 37, 117 122.
30. Porter, W.T. (1895) The path of the respiratory impulse from the bulb to the phrenic nuclei. J. Physiol., 17, 455 485.
31. Vinit, S., Gauthier, P., Stamegna, J.C. Kastner, A. (2006) High cervical lateral spinal cord injury results in long-term ipsilateral hemidiaphragm paralysis. J. Neurotrauma, 23, 1137 1146.
32. Vinit, S., Stamegna, J.C., Boulenguez, P., Gauthier, P. Kastner, A. (2007) Restorative respiratory pathways after partial cervical spinal cord injury: role of ipsilateral phrenic afferents. Eur. J. Neurosci., 25, 3551 3560.
33. Weidner, N., Ner, A., Salimi, N. Tuszynski, M.H. (2001) Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury. P.N.A.S., 98, 3513 3518.
34. Winslow, C. Rozovsky, J. (2003) Effect of spinal cord injury on the respiratory system. Am. J. Phys. Med. Rehabil., 82, 803 814.