Association between monoamine oxidase (MAO)-A gene variants and schizophrenia in a Chinese population

Brain Research

Volumn 1287, Issue , 2009, Pages 67-73

  Qiu, Hai Tang ^a   Meng, Hua Qing ^a   Song, Cai ^b   Xiu, Mei Hong ^c   Chen, Da Chun ^c   Zhu, Feng Yan ^c   Wu, Gui Ying ^d   Kosten, Therese A ^d   Kosten, Thomas R ^d   Zhang, Xiang Yang ^c,d  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

^c BEIJING HUILONGGUAN HOSPITAL   (China)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Association; Case control; Haplotype; MAO; Polymorphism; Schizophrenia

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A;

ADULT; ALLELE; ARTICLE; CHINESE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHIZOPHRENIA; TANDEM REPEAT;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; LINKAGE (GENETICS); LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MONOAMINE OXIDASE; POLYMORPHISM, GENETIC; SCHIZOPHRENIA; SEX FACTORS;

EID: 68049091868     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.06.072     Document Type: Article

References (30)

1. Baron M., Risch N., Levitt M., and Gruen R. Genetic analysis of platelet monoamine oxidase activity in families of schizophrenic patients. J. Psychiatr. Res. 19 (1985) 9-21
2. Cardon L.R., and Bell J.I. Association study designs for complex diseases. Nat. Rev., Genet. 2 (2001) 91-99
3. Chen Z.Y., Hotamisligil G.S., Huang J.K., Wen L., Ezzeddine D., Aydin-Muderrisoglu N., Powell J.F., Huang R.H., Breakefield X.O., and Craig I. Structure of the human gene for monoamine oxidase type A. Nucleic Acids Res. 19 (1991) 4537-4541
4. Davis K.L., Kahn R.S., Ko G., and Davidson M. Dopamine in schizophrenia: a review and reconceptualization. Am. J. Psychiatry 148 (1991) 1471-1486
5. Deckert J., Catalano M., Syagailo Y.V., Bosi M., Okladnova O., Di Bella D., Nothen M.M., Maffei P., Franke P., Fritze J., Maier W., Propping P., Beckmann H., Bellodi L., and Lesch K.P. Excess of high activity monoamine oxidase A gene promoter alleles in female patients with panic disorder. Hum. Mol. Genet. 8 (1999) 621-624
6. Fowler J.S., MacGregor R.R., Wolf A.P., Arnett C.D., Dewey S.L., Schlyer D., Christman D., Logan J., Smith M., Sachs H., Aquilonius S.M., Bjurling P., Halldin C., Hartvig P., Leenders K.L., Lundqvist H., Oreland L., Stalnacke C.G., and Langstrom B. Mapping human brain monoamine oxidase A and B with 11C-labeled suicide inactivators and PET. Science 235 (1987) 481-485
7. Furlong R.A., Ho L., Rubinsztein J.S., Walsh C., Paykel E.G., and Rubinsztein D.C. Analysis of the monoamine oxidase A (MAOA) gene in bipolar affective disorder by association studies, meta-analyses, and sequencing of the promoter. Am. J. Med. Genet. 88 (1999) 398-406
8. Gabriel S.B., Schaffner S.F., Nguyen H., Moore J.M., Roy J., Blumenstiel B., Higgins J., DeFelice M., Lochner A., Faggart M., Liu-Cordero S.N., Rotimi C., Adeyemo A., Cooper R., Ward R., Lander E.S., Daly M.J., and Altshuler D. The structure of haplotype blocks in the human genome. Science 296 (2002) 2225-2229
9. Gauderman W.J. Sample size requirements for association studies of gene-gene interaction. Am. J. Epidemiol. 155 (2002) 478-484
10. Hotamisligil G.S., and Breakefield X.O. Human monoamine oxidase A gene determines levels of enzyme activity. Am. J. Hum. Genet. 49 (1991) 383-392
11. Jonsson E.G., Norton N., Forslund K., Mattila-Evenden M., Rylander G., Asberg M., Owen M.J., and Sedvall G.C. Association between a promoter variant in the monoamine oxidase A gene and schizophrenia. Schizophr. Res. 61 (2003) 31-37
12. Karayiorgou M., Sobin C., Blundell M.L., Galke B.L., Malinova L., Goldberg P., Ott J., and Gogos J.A. Family-based association studies support a sexually dimorphic effect of COMT and MAOA on genetic susceptibility to obsessive-compulsive disorder. Biol. Psychiatry 45 (1999) 1178-1189
13. Lan N.C., Heinzmann C., Gal A., Klisak I., Orth U., Lai E., Grimsby J., Sparkes R.S., Mohandas T., and Shih J.C. Human monoamine oxidase A and B genes map to Xp 11.23 and are deleted in a patient with Norrie disease. Genomics 4 (1989) 552-559
14. Lang, U.E., Puls, I., Muller, D.J., Strutz-Seebohm, N., Gallinat, J., 2007. Molecular mechanisms of schizophrenia. Cell. Physiol. Biochem. 20, 687-702.
15. Lee W.C. Detecting population stratification using a panel of single nucleotide polymorphisms. Int. J. Epidemiol. 32 (2003) 1120
16. Lohmueller K.E., Pearce C.L., Pike M., Lander E.S., and Hirschhorn J.N. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat. Genet. 33 (2003) 177-182
17. Luo X., Kranzler H.R., Zuo L., Yang B.Z., Lappalainen J., and Gelernter J. ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies. Pharmacogenet. Genomics 15 (2005) 755-768
18. Muller D.J., Serretti A., Sicard T., Tharmalingam S., King N., Artioli P., Mandelli L., Lorenzi C., and Kennedy J.L. Further evidence of MAO-A gene variants associated with bipolar disorder. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144 (2007) 37-40
19. Murphy D.L., and Wyatt R.J. Reduced monoamine oxidase activity in blood platelets from schizophrenic patients. Nature 238 (1972) 225-226
20. Norton N., Kirov G., Zammit S., Jones G., Jones S., Owen R., Krawczak M., Williams N.M., O'Donovan M.C., and Owen M.J. Schizophrenia and functional polymorphisms in the MAOA and COMT genes: no evidence for association or epistasis. Am. J. Med. Genet. 114 (2002) 491-496
21. Pedersen N.L., Oreland L., Reynolds C., and McClearn G.E. Importance of genetic effects for monoamine oxidase activity in thrombocytes in twins reared apart and twins reared together. Psychiatry Res. 46 (1993) 239-251
22. Rubinsztein D.C., Leggo J., Goodburn S., Walsh C., Jain S., and Paykel E.S. Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: analysis and meta-analysis. Hum. Mol. Genet. 5 (1996) 779-782
23. Sabol S.Z., Hu S., and Hamer D. A functional polymorphism in the monoamine oxidase A gene promoter. Hum. Genet. 103 (1998) 273-279
24. Sham P.C., and Curtis D. Monte Carlo tests for associations between disease and alleles at highly polymorphic loci. Ann. Hum. Genet. 59 (1995) 97-105
25. Shih J.C., and Thompson R.F. Monoamine oxidase in neuropsychiatry and behavior. Am. J. Hum. Genet. 65 (1999) 593-598
26. Syagailo Y.V., Stober G., Grassle M., Reimer E., Knapp M., Jungkunz G., Okladnova O., Meyer J., and Lesch K.P. Association analysis of the functional monoamine oxidase A gene promoter polymorphism in psychiatric disorders. Am. J. Med. Genet. 105 (2001) 168-171
27. Wei J., and Hemmings G.P. A study of linkage disequilibrium between polymorphic loci for monamine oxidases A and B in schizophrenia. Psychiatr. Genet. 9 (1999) 177-181
28. Williams N.M., Rees M.I., Holmans P., Norton N., Cardno A.G., Jones L.A., Murphy K.C., Sanders R.D., McCarthy G., Gray M.Y., Fenton I., McGuffin P., and Owen M.J. A two-stage genome scan for schizophrenia susceptibility genes in 196 affected sibling pairs. Hum. Mol. Genet. 8 (1999) 1729-1739
29. Zalsman G., Huang Y.Y., Harkavy-Friedman J.M., Oquendo M.A., Ellis S.P., and Mann J.J. Relationship of MAO-A promoter (u-VNTR) and COMT (V158M) gene polymorphisms to CSF monoamine metabolites levels in a psychiatric sample of Caucasians: a preliminary report. Am. J. Med. Genet. B Neuropsychiatr. Genet. 132 (2005) 100-103
30. Zhu Q.S., Grimsby J., Chen K., and Shih J.C. Promoter organization and activity of human monoamine oxidase (MAO) A and B genes. J. Neurosci. 12 (1992) 4437-4446