Crude cacao Theobroma cacao extract reduces mutagenicity induced by benzo[a]pyrene through inhibition of CYP1A activity in vitro

Phytotherapy Research

Volumn 23, Issue 8, 2009, Pages 1134-1139

  Ohno, Marumi ^a   Sakamoto, Kentaro Q ^a   Ishizuka, Mayumi ^a   Fujita, Shoichi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Antimutagenic effect; Cacao; Cytochrome P450; Metabolic activation; Polyphenol; Radical scavenging

Indexed keywords

BENZO[A]PYRENE; CACAO EXTRACT; CYTOCHROME P450 1A; ETHOXYRESORUFIN DEETHYLASE; FREE RADICAL; PLANT EXTRACT; POLYPHENOL DERIVATIVE; REACTIVE OXYGEN METABOLITE; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG;

AMES TEST; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; CACAO; CONTROLLED STUDY; DNA DAMAGE; DNA SEQUENCE; ENZYME ACTIVITY; IN VITRO STUDY; MALE; METABOLIC ACTIVATION; MUTAGENICITY; NONHUMAN; RAT; SALMONELLA TYPHIMURIUM;

ANIMALS; BENZO(A)PYRENE; CACAO; CYTOCHROME P-450 CYP1A1; FREE RADICAL SCAVENGERS; MALE; MUTAGENICITY TESTS; PLANT EXTRACTS; RATS; RATS, WISTAR; SALMONELLA TYPHIMURIUM; TERT-BUTYLHYDROPEROXIDE;

SALMONELLA TYPHIMURIUM; THEOBROMA CACAO;

EID: 68049084442     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2762     Document Type: Article

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