Fluorinated quinine alkaloids: Synthesis, X-ray structure analysis and antimalarial parasite chemotherapy

Chemistry - A European Journal

Volumn 15, Issue 31, 2009, Pages 7637-7647

  Bucher, Christoph ^a   Sparr, Christof ^a   Schweizer, W Bernd ^a   Gilmour, Ryan ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Alkaloids; Fluorine; Gauche effect; Malaria; Medicinal chemistry; Parasite chemotherapy

Indexed keywords

ALKALOIDS; GAUCHE EFFECT; MALARIA; MEDICINAL CHEMISTRY; PARASITE CHEMOTHERAPY;

AMINES; AMMONIUM COMPOUNDS; ATOMS; CHEMOTHERAPY; COMPLEXATION; FLUORINE; ORGANIC POLYMERS;

X RAY DIFFRACTION ANALYSIS;

ALKALOID; ANTIMALARIAL AGENT; DRUG DERIVATIVE; FLUORINATED HYDROCARBON; QUININE;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; CONFORMATION; DRUG EFFECT; GENETICS; PLASMODIUM FALCIPARUM; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ALKALOIDS; ANIMALS; ANTIMALARIALS; COMBINATORIAL CHEMISTRY TECHNIQUES; CRYSTALLOGRAPHY, X-RAY; HYDROCARBONS, FLUORINATED; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PLASMODIUM FALCIPARUM; QUININE;

EID: 67949094197     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200900505     Document Type: Article

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