-
2
-
-
0032839614
-
-
Williams, N. H.; Takasaki, B.; Wall, M.; Chin, J. Acc. Chem. Res. 1999, 32, 485-493.
-
(1999)
Acc. Chem. Res
, vol.32
, pp. 485-493
-
-
Williams, N.H.1
Takasaki, B.2
Wall, M.3
Chin, J.4
-
6
-
-
20444439223
-
-
Mancin, F.; Scrimin, P.; Tecilla, P.; Tonellato, U. Chem. Commun. 2005, 2540-2548.
-
(2005)
Chem. Commun
, pp. 2540-2548
-
-
Mancin, F.1
Scrimin, P.2
Tecilla, P.3
Tonellato, U.4
-
8
-
-
0002421061
-
-
Komiyama, M.; Shiiba, T.; Takahashi, Y.; Takeda, N.; Matsumura, K.; Kodama, T. Supramol. Chem. 1994, 4, 31-34.
-
(1994)
Supramol. Chem
, vol.4
, pp. 31-34
-
-
Komiyama, M.1
Shiiba, T.2
Takahashi, Y.3
Takeda, N.4
Matsumura, K.5
Kodama, T.6
-
10
-
-
0348223916
-
-
Zelder, F. H.; Mokhir, A. A.; Kramer, R. Inorg. Chem. 2003, 42, 8618-8620.
-
(2003)
Inorg. Chem
, vol.42
, pp. 8618-8620
-
-
Zelder, F.H.1
Mokhir, A.A.2
Kramer, R.3
-
11
-
-
0025797398
-
-
For this purpose, naturally occurring nucleases were combined with DNA-binding molecules. Alternatively, restriction enzyme sites in substrate DNA, except for the target site, were protected by methylation, and then this substrate was treated with the enzyme. See:(a). Strobel, S. A.; Dervan, P. E. Nature 1991, 350, 172-174.
-
For this purpose, naturally occurring nucleases were combined with DNA-binding molecules. Alternatively, restriction enzyme sites in substrate DNA, except for the target site, were protected by methylation, and then this substrate was treated with the enzyme. See:(a). Strobel, S. A.; Dervan, P. E. Nature 1991, 350, 172-174.
-
-
-
-
12
-
-
0029989057
-
-
(b). Veselkov, A. G.; Demidov, V. V.; Nielsen, P. E.; Frank-Kamenetskii, M. D. Nucleic Acids Res. 1996, 24, 2483-2487.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 2483-2487
-
-
Veselkov, A.G.1
Demidov, V.V.2
Nielsen, P.E.3
Frank-Kamenetskii, M.D.4
-
13
-
-
0034066219
-
-
Arimondo, P. B.; Moreau, P.; Boutorine, A.; Bailly, C.; Prudhomme, M.; Sun, J.-S.; Garestier, T.; Hélène, C. Bioorg. Med. Chem. 2000, 8, 777-784.
-
(2000)
Bioorg. Med. Chem
, vol.8
, pp. 777-784
-
-
Arimondo, P.B.1
Moreau, P.2
Boutorine, A.3
Bailly, C.4
Prudhomme, M.5
Sun, J.-S.6
Garestier, T.7
Hélène, C.8
-
14
-
-
31144471228
-
-
Eisen-schmidt, K.; Lanio, T.; Simoncsits, A.; Jeltsch, A.; Pingoud, V.; Wende, W.; Pingoud, A. Nucleic Acids Res. 2005, 33, 7039-7047.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 7039-7047
-
-
Eisen-schmidt, K.1
Lanio, T.2
Simoncsits, A.3
Jeltsch, A.4
Pingoud, V.5
Wende, W.6
Pingoud, A.7
-
15
-
-
34447319080
-
-
(e). Miller, J. C.; Holmes, M. C.; Wang, J.; Guschin, D. Y.; Lee, Y. L.; Rupniewski, I.; Beausejour, C. M.; Waite, A. J.; Wang, N. S.; Kim, K. A.; Gregory, P. D.; Pabo, C. O.; Rebar, E. J. Nat. Biotechnol. 2007, 25, 778-785.
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 778-785
-
-
Miller, J.C.1
Holmes, M.C.2
Wang, J.3
Guschin, D.Y.4
Lee, Y.L.5
Rupniewski, I.6
Beausejour, C.M.7
Waite, A.J.8
Wang, N.S.9
Kim, K.A.10
Gregory, P.D.11
Pabo, C.O.12
Rebar, E.J.13
-
16
-
-
42049094396
-
-
Komiyama, M.; Aiba, Y.; Ishizuka, T.; Sumaoka, J. Nat. Protoc. 2008, 3, 646-654.
-
(2008)
Nat. Protoc
, vol.3
, pp. 646-654
-
-
Komiyama, M.1
Aiba, Y.2
Ishizuka, T.3
Sumaoka, J.4
-
17
-
-
42049106385
-
-
Komiyama, M.; Aiba, Y.; Yamamoto, Y.; Sumaoka, J. Nat. Protoc. 2008, 3, 655-662.
-
(2008)
Nat. Protoc
, vol.3
, pp. 655-662
-
-
Komiyama, M.1
Aiba, Y.2
Yamamoto, Y.3
Sumaoka, J.4
-
18
-
-
54349092387
-
-
Tanaka, K.; Katada, H.; Shigi, N.; Kuzuya, A.; Komiyama, M. ChemBioChem 2008, 9, 2120-2126.
-
(2008)
ChemBioChem
, vol.9
, pp. 2120-2126
-
-
Tanaka, K.1
Katada, H.2
Shigi, N.3
Kuzuya, A.4
Komiyama, M.5
-
19
-
-
41149158074
-
-
Ishizuka, T.; Yoshida, J.; Yamamoto, Y.; Sumaoka, J.; Tedeschi, T.; Corradini, R.; Sforza, S.; Komiyama, M. Nucleic Acids Res. 2008, 36, 1464-1471.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 1464-1471
-
-
Ishizuka, T.1
Yoshida, J.2
Yamamoto, Y.3
Sumaoka, J.4
Tedeschi, T.5
Corradini, R.6
Sforza, S.7
Komiyama, M.8
-
20
-
-
34249847680
-
-
A monophosphate group was attached to the N-terminus of each of these two pcPNAs to improve the scission efficiency. See: Yamamoto, Y, Mori, M, Aiba, Y, Tomita, T, Chen, W, Zhou, J.-M, Uehara, A, Ren, Y, Kitamura, Y, Komiyama, M. Nucleic Acids Res. 2007, 35, e53
-
A monophosphate group was attached to the N-terminus of each of these two pcPNAs to improve the scission efficiency. See: Yamamoto, Y.; Mori, M.; Aiba, Y.; Tomita, T.; Chen, W.; Zhou, J.-M.; Uehara, A.; Ren, Y.; Kitamura, Y.; Komiyama, M. Nucleic Acids Res. 2007, 35, e53.
-
-
-
-
21
-
-
34347267230
-
-
Aiba, Y.; Yamamoto, Y.; Komiyama, M. Chem. Lett. 2007, 36, 780-781.
-
(2007)
Chem. Lett
, vol.36
, pp. 780-781
-
-
Aiba, Y.1
Yamamoto, Y.2
Komiyama, M.3
-
22
-
-
33748125140
-
-
Yamamoto, Y.; Miura, K.; Komiyama, M. Chem. Lett. 2006, 35, 594-595.
-
(2006)
Chem. Lett
, vol.35
, pp. 594-595
-
-
Yamamoto, Y.1
Miura, K.2
Komiyama, M.3
-
23
-
-
33645754215
-
-
Yamamoto, Y.; Uehara, A.; Watanabe, A.; Aburatani, H.; Komiyama, M. ChemBioChem 2006, 7, 673-677.
-
(2006)
ChemBioChem
, vol.7
, pp. 673-677
-
-
Yamamoto, Y.1
Uehara, A.2
Watanabe, A.3
Aburatani, H.4
Komiyama, M.5
-
24
-
-
15444370270
-
-
Yamamoto, Y.; Uehara, A.; Tomita, T.; Komiyama, M. Nucleic Acids Res. 2004, 32, e153.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Yamamoto, Y.1
Uehara, A.2
Tomita, T.3
Komiyama, M.4
-
25
-
-
0026341239
-
-
Nielsen, P. E.; Egholm, M.; Berg, R. H.; Buchardt, O. Science 1991, 254, 1497-1500.
-
(1991)
Science
, vol.254
, pp. 1497-1500
-
-
Nielsen, P.E.1
Egholm, M.2
Berg, R.H.3
Buchardt, O.4
-
26
-
-
0027364174
-
-
Egholm, M.; Buchardt, O.; Christensen, L.; Behrens, C.; Freier, S. M.; Driver, D. A.; Berg, R. H.; Kim, S. K.; Norden, B.; Nielsen, P. E. Nature 1993, 365, 566-568.
-
(1993)
Nature
, vol.365
, pp. 566-568
-
-
Egholm, M.1
Buchardt, O.2
Christensen, L.3
Behrens, C.4
Freier, S.M.5
Driver, D.A.6
Berg, R.H.7
Kim, S.K.8
Norden, B.9
Nielsen, P.E.10
-
27
-
-
0032738421
-
-
Induction of local structural changes in double-stranded DNA by PNA invasion has been clearly evidenced. See: a, Lohse, J, Dahl, O, Nielsen, P. E. Proc. Natl. Acad. Sci. U.S.A. 1999, 96, 11804-11808
-
Induction of local structural changes in double-stranded DNA by PNA invasion has been clearly evidenced. See: (a). Lohse, J.; Dahl, O.; Nielsen, P. E. Proc. Natl. Acad. Sci. U.S.A. 1999, 96, 11804-11808.
-
-
-
-
28
-
-
2442672906
-
-
(b). Kuhn, H.; Cherny, D. I.; Demidov, V. V.; Frank-Kamenetskii, M. D. Proc. Natl. Acad. Sci. U.S.A. 2004,101, 7548-7553.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A
, vol.101
, pp. 7548-7553
-
-
Kuhn, H.1
Cherny, D.I.2
Demidov, V.V.3
Frank-Kamenetskii, M.D.4
-
29
-
-
0030780913
-
-
Haaima, G.; Hansen, H. F.; Christensen, L.; Dahl, O.; Nielsen, P. E. Nucleic Acids Res. 1997, 25, 4639-4643.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4639-4643
-
-
Haaima, G.1
Hansen, H.F.2
Christensen, L.3
Dahl, O.4
Nielsen, P.E.5
-
30
-
-
37849040469
-
-
Rapireddy, S.; He, G.; Roy, S.; Armitage, B. A.; Ly, D. H. J. Am. Chem. Soc. 2007, 129, 1559615600 Furthermore, enzymatic reactions were controlled by PNA invasion. See:
-
Rapireddy, S.; He, G.; Roy, S.; Armitage, B. A.; Ly, D. H. J. Am. Chem. Soc. 2007, 129, 1559615600) Furthermore, enzymatic reactions were controlled by PNA invasion. See:
-
-
-
-
31
-
-
0034609587
-
-
(e). Izvolsky, K. I.; Demidov, V. V.; Nielsen, P. E.; FrankKamenetskii, M. D Biochemistry 2000, 39, 10908-10913.
-
(2000)
Biochemistry
, vol.39
, pp. 10908-10913
-
-
Izvolsky, K.I.1
Demidov, V.V.2
Nielsen, P.E.3
FrankKamenetskii, M.D.4
-
32
-
-
0043148263
-
-
(f). Protozanova, E.; Demidov, V. V.; Nielsen, P. E.; Frank-Kamenetskii, M. D. Nucleic Acids Res. 2003, 31, 3929-3935.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3929-3935
-
-
Protozanova, E.1
Demidov, V.V.2
Nielsen, P.E.3
Frank-Kamenetskii, M.D.4
-
34
-
-
4143153938
-
-
Chen, W.; Kitamura, Y.; Zhou, J.-M.; Sumaoka, J.; Komiyama, M. J. Am. Chem. Soc. 2004, 126, 10285-10291.
-
(2004)
J. Am. Chem. Soc
, vol.126
, pp. 10285-10291
-
-
Chen, W.1
Kitamura, Y.2
Zhou, J.-M.3
Sumaoka, J.4
Komiyama, M.5
-
35
-
-
29544452462
-
-
Kitamura, Y.; Mori, S.; Chen, W.; Sumaoka, J.; Komiyama, M. J. Biol. Inorg. Chem. 2006, 11, 13-16.
-
(2006)
J. Biol. Inorg. Chem
, vol.11
, pp. 13-16
-
-
Kitamura, Y.1
Mori, S.2
Chen, W.3
Sumaoka, J.4
Komiyama, M.5
-
36
-
-
52149096527
-
-
Lonnberg, T.; Suzuki, Y.; Komiyama, M. Org. Biomol. Chem. 2008, 6, 3580-3587.
-
(2008)
Org. Biomol. Chem
, vol.6
, pp. 3580-3587
-
-
Lonnberg, T.1
Suzuki, Y.2
Komiyama, M.3
-
37
-
-
84925567853
-
-
The scission bands in lanes 3-5, if present, were at least 100-fold weaker than those in lane 2
-
The scission bands in lanes 3-5, if present, were at least 100-fold weaker than those in lane 2.
-
-
-
-
38
-
-
84925567852
-
-
The gel mobilities of the invasion complexes in Figure 6 differed from lane to lane. It is probable that the magnitude of the bending of the substrate DNA induced by the invasion is dependent on the kind of mismatch incorporated at the invasion site.
-
The gel mobilities of the invasion complexes in Figure 6 differed from lane to lane. It is probable that the magnitude of the bending of the substrate DNA induced by the invasion is dependent on the kind of mismatch incorporated at the invasion site.
-
-
-
-
39
-
-
84925561456
-
-
It should be noted that the invasion complex has pseudo-C 2 symmetry when the difference in sequence is neglected see Figure 1
-
2 symmetry when the difference in sequence is neglected (see Figure 1).
-
-
-
|